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Search results 1 to 88 out of 88 for Parp3

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Hits by Category

Hits by Strain

Type Details Score
Gene
10039 | PARP3
Type: gene
Organism: human
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Gene
100145803 | parp3
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR031275 | PARP3
Type: Family
Description: PARP3 belongs to the poly-ADP-ribose polymerase (PARP) family. It plays a role in DSB (double-strand break) repair by promoting the recruitment of aprataxin-like factor (APLF) to sites of damage. It is preferentially activated by DNA breaks harbouring a 5' phosphate (5'P) [].Poly(ADP-ribosyl)ation (PARylation) is a post-translational modification of proteins []. PARP family members are PAR polymerases that initiate the reaction by converting the substrate nicotinamide adenine dinucleotide (NAD+) to ADP-ribose, and then catalyse ADP-ribose polymerisation on nuclear acceptor proteins [].
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Gene
300985 | Parp3
Type: gene
Organism: rat
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Gene
484745 | PARP3
Type: gene
Organism: dog, domestic
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Gene
460409 | PARP3
Type: gene
Organism: chimpanzee
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Gene
507426 | PARP3
Type: gene
Organism: cattle
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Gene
771158 | PARP3
Type: gene
Organism: chicken
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Gene
335495 | parp3
Type: gene
Organism: zebrafish
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Gene
699294 | PARP3
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1891258 | Parp3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
26000965 | J:274078
First Author: Robert I
Year: 2015
Journal: PLoS Genet
Title: Parp3 negatively regulates immunoglobulin class switch recombination.
Volume: 11
Issue: 5
Pages: e1005240
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Protein
Q3ULW8
Organism: Mus musculus/domesticus
Length: 533  
Fragment?: false
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Protein
A0A5H1ZRL8
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: true
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Protein
A0A5H1ZRL5
Organism: Mus musculus/domesticus
Length: 202  
Fragment?: true
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Publication
30213852 | J:336603
First Author: Layer JV
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Parp3 promotes long-range end joining in murine cells.
Volume: 115
Issue: 40
Pages: 10076-10081
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Publication
24928857 | -
First Author: Langelier MF
Year: 2014
Journal: Nucleic Acids Res
Title: PARP-2 and PARP-3 are selectively activated by 5' phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1.
Volume: 42
Issue: 12
Pages: 7762-75
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Publication
21840394 | -
First Author: Abd Elmageed ZY
Year: 2012
Journal: Cell Signal
Title: The poly(ADP-ribose) polymerases (PARPs): new roles in intracellular transport.
Volume: 24
Issue: 1
Pages: 1-8
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Publication
10455009 | -
 
First Author: D'Amours D
Year: 1999
Journal: Biochem J
Title: Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions.
Volume: 342 ( Pt 2)
Pages: 249-68
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Publication
21270334 | J:170941
First Author: Boehler C
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression.
Volume: 108
Issue: 7
Pages: 2783-8
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Protein
A0A5H1ZRP0
Organism: Mus musculus/domesticus
Length: 351  
Fragment?: true
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GXD Expression
GXD Expression
 
Probe: MGI:7544976
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-01
Strength: Present
Sex: Female
Emaps: EMAPS:1657819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7545029
Age: embryonic day 11.5
Note: There was no significant difference in the proportion of Parp3 positive cells compared with the wild-type (quantified in Fig 9D).
Specimen Label: 9C E11.5 -/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7544976
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-01
Strength: Present
Sex: Female
Emaps: EMAPS:1657820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7545029
Age: embryonic day 12.5
Note: There was no significant difference in the proportion of Parp3 positive cells compared with the wild-type (quantified in Fig 9D).
Specimen Label: 9C E12.5 -/-
Detected: true
Specimen Num: 4
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Publication
12448766 | J:79987
First Author: Urbánek P
Year: 2002
Journal: Folia Biol (Praha)
Title: Cloning and expression of PARP-3 (Adprt3) and U3-55k, two genes closely linked on mouse chromosome 9.
Volume: 48
Issue: 5
Pages: 182-91
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Protein Coding Gene
MGP_CAROLIEiJ_G0032625 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035234 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035213 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035145 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035207 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034917 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1891258 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035727 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034228 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034885 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035046 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034994 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035122 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035033 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035748 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033935 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034349 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015493 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033770 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:7544976
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-01
Strength: Present
Sex: Female
Emaps: EMAPS:1657819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7545029
Age: embryonic day 11.5
Specimen Label: 9C E11.5 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7544976
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-01
Strength: Present
Sex: Female
Emaps: EMAPS:1657820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7545029
Age: embryonic day 12.5
Specimen Label: 9C E12.5 +/+
Detected: true
Specimen Num: 3
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Publication
21211721 | J:168260
First Author: Rulten SL
Year: 2011
Journal: Mol Cell
Title: PARP-3 and APLF function together to accelerate nonhomologous end-joining.
Volume: 41
Issue: 1
Pages: 33-45
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Publication
37563658 | J:340875
First Author: Zhou Z
Year: 2023
Journal: J Ovarian Res
Title: Fance deficiency inhibits primordial germ cell proliferation associated with transcription-replication conflicts accumulate and DNA repair defects.
Volume: 16
Issue: 1
Pages: 160
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q3ULW8-2
Organism: Mus musculus/domesticus
Length: 528  
Fragment?: false
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Publication
24598253 | -
First Author: Beck C
Year: 2014
Journal: Nucleic Acids Res
Title: PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.
Volume: 42
Issue: 9
Pages: 5616-32
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UniProt Feature
UniProt Feature
Begin: 1
Description: Protein mono-ADP-ribosyltransferase PARP3
Type: chain
End: 533
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Publication
27550455 | J:236246
First Author: Oplustil O'Connor L
Year: 2016
Journal: Cancer Res
Title: The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models.
Volume: 76
Issue: 20
Pages: 6084-6094
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GXD Expression
GXD Expression
 
Probe: MGI:6694992
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-01
Strength: Present
Sex: Female
Emaps: EMAPS:1657819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7544998
Age: embryonic day 11.5
Note: There was no significant difference in the proportion of Parp3 positive cells compared with the wild-type (quantified in Fig 9D).
Specimen Label: 9C E11.5 -/-
Detected: true
Specimen Num: 42
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GXD Expression
GXD Expression
 
Probe: MGI:6694992
Assay Type: Immunohistochemistry
Annotation Date: 2023-11-01
Strength: Present
Sex: Female
Emaps: EMAPS:1657820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7544998
Age: embryonic day 12.5
Note: There was no significant difference in the proportion of Parp3 positive cells compared with the wild-type (quantified in Fig 9D).
Specimen Label: 9C E12.5 -/-
Detected: true
Specimen Num: 44
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Publication
28105679 | J:246409
First Author: Robert I
Year: 2017
Journal: Eur J Immunol
Title: Robust immunoglobulin class switch recombination and end joining in Parp9-deficient mice.
Volume: 47
Issue: 4
Pages: 665-676
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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