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Search results 1 to 86 out of 86 for Pate2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: PATE proteins are secreted, small, cysteine-rich proteins selectively expressed in male reproductive tissues (prostate, testis, epididymis, seminal vesicle).This proteins include 10 cysteine residues conforms to a consensus cysteine pattern found in a well-conserved large family of three-fingered proteins (TFPs), characterised by a distinct disulfide bonding pattern between 8 and 10 cysteine residues []. Critical roles of the PATE (Pate)-like proteins in activities related not only to fertility and reproduction but also to neuronal activity. Neurons and sperm share many common "neuron specific"receptors. Nicotinic acetylcholine receptors (nACHR) subunits alpha7, 9, 3, 5 and beta 4 have all beendemonstrated to be present in human sperm and the alpha-7 subunit likely exists as a homomer in the posterior post-acrosomal and neck regions of sperm. Human acrosome reaction initiated by acetylcholine involves the alpha-7 nAChR []. Common functionality of nAChR in both reproductive and neuronal tissues thus reconciles the neuro-modulatory activity of the PATE (Pate)-like proteins.Prostate and testis expressed protein 2 (PATE2, also known as PATE-M) belongs to the PATE family and is expressed in prostate and testis [].
Publication
First Author: Levitin F
Year: 2008
Journal: J Biol Chem
Title: PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity.
Volume: 283
Issue: 24
Pages: 16928-39
Protein
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 108  
Fragment?: true
Publication
First Author: Margalit M
Year: 2012
Journal: Hum Reprod
Title: Involvement of the prostate and testis expression (PATE)-like proteins in sperm-oocyte interaction.
Volume: 27
Issue: 5
Pages: 1238-48
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863704
Specimen Label: UC Davis_1863704
Detected: true
Specimen Num: 9
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863712
Note: vas deferens
Specimen Label: UC Davis_1863712
Detected: true
Specimen Num: 17
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863702
Specimen Label: UC Davis_1863702
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1893928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863703
Specimen Label: UC Davis_1863703
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1718528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863705
Specimen Label: UC Davis_1863705
Detected: true
Specimen Num: 10
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1918028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863716
Note: vesicular gland
Specimen Label: UC Davis_1863716
Detected: true
Specimen Num: 21
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1918028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863713
Note: vesicular gland
Specimen Label: UC Davis_1863713
Detected: true
Specimen Num: 18
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1918028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863714
Note: vesicular gland
Specimen Label: UC Davis_1863714
Detected: true
Specimen Num: 19
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863715
Specimen Label: UC Davis_1863715
Detected: true
Specimen Num: 20
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863706
Specimen Label: UC Davis_1863706
Detected: true
Specimen Num: 11
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863707
Specimen Label: UC Davis_1863707
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863708
Specimen Label: UC Davis_1863708
Detected: true
Specimen Num: 13
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863711
Specimen Label: UC Davis_1863711
Detected: true
Specimen Num: 16
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1885228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863699
Specimen Label: UC Davis_1863699
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863698
Specimen Label: UC Davis_1863698
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863717
Specimen Label: UC Davis_1863717
Detected: true
Specimen Num: 22
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863709
Specimen Label: UC Davis_1863709
Detected: true
Specimen Num: 14
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863710
Specimen Label: UC Davis_1863710
Detected: true
Specimen Num: 15
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863700
Specimen Label: UC Davis_1863700
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863701
Specimen Label: UC Davis_1863701
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863719
Specimen Label: UC Davis_1863719
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1881228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692842
Age: postnatal adult
Image: UC Davis_1863696
Specimen Label: UC Davis_1863696
Detected: true
Specimen Num: 2
Publication
First Author: Kaplan N
Year: 2007
Journal: J Mol Biol
Title: Novel families of toxin-like peptides in insects and mammals: a computational approach.
Volume: 369
Issue: 2
Pages: 553-66
Publication
First Author: Noda T
Year: 2019
Journal: Andrology
Title: Nine genes abundantly expressed in the epididymis are not essential for male fecundity in mice.
Volume: 7
Issue: 5
Pages: 644-653
Publication  
First Author: Loughner CL
Year: 2016
Journal: Hum Genomics
Title: Organization, evolution and functions of the human and mouse Ly6/uPAR family genes.
Volume: 10
Pages: 10
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Allele
Name: prostate and testis expressed 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: deletion, Chr 9, Research Institute for Microbial Diseases, Osaka University 4
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: Research Institute for Microbial Diseases, Osaka University 5; deletion, Chr 9, Research Institute for Microbial Diseases, Osaka University 5
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Strain
Attribute String: endonuclease-mediated mutation, mutant stock
Strain
Attribute String: endonuclease-mediated mutation, mutant stock
Publication
First Author: Fujihara Y
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice.
Volume: 116
Issue: 37
Pages: 18498-18506