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Search results 1 to 100 out of 1365 for Pax1

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Type Details Score
Gene
5075 | PAX1
Type: gene
Organism: human
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Gene
537696 | PAX1
Type: gene
Organism: cattle
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Gene
100859138 | PAX1
Type: gene
Organism: chicken
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Gene
706866 | PAX1
Type: gene
Organism: macaque, rhesus
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Gene
100038212 | pax1
Type: gene
Organism: frog, western clawed
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Gene
311505 | Pax1
Type: gene
Organism: rat
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Gene
485743 | PAX1
Type: gene
Organism: dog, domestic
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Gene
458132 | PAX1
Type: gene
Organism: chimpanzee
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Protein Domain
IPR033206 | PAX1
Type: Family
Description: PAX1 belongs to the PAX family. PAX1 and PAX9 synergistically act in the proper formation of the vertebral column and play an important role in the formation of the vertebrate axial skeleton, regulating cell proliferation and chondrogenic specification in the sclerotome []. PAX1 also functions as a negative regulator of chondrocyte maturation [].PAX family members are transcription factors characterised by a ~128-amino-acid DNA-binding paired domain that makes sequence specific contacts with DNA []. In mammals, there are nine Pax proteins (PAX1-9). They regulate the morphogenesis of a wide range of organs and are key factors for the development of mammalian sensory organs such as the eye (Pax6, Pax2), nose (Pax6) and ears (Pax2, Pax8) [, ].
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Protein Coding Gene
MGI:97485 | Pax1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
12490554 | J:81151
First Author: Rodrigo I
Year: 2003
Journal: Development
Title: Pax1 and Pax9 activate Bapx1 to induce chondrogenic differentiation in the sclerotome.
Volume: 130
Issue: 3
Pages: 473-82
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Protein
Q548R5
Organism: Mus musculus/domesticus
Length: 361  
Fragment?: false
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Protein
Q8K4Q1
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: true
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Publication
24080012 | -
First Author: Takimoto A
Year: 2013
Journal: Exp Cell Res
Title: Pax1 acts as a negative regulator of chondrocyte maturation.
Volume: 319
Issue: 20
Pages: 3128-39
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GXD Expression
GXD Expression
   
Probe: MGI:5754370
Assay Type: RNA in situ
Annotation Date: 2016-03-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1675215
Stage: TS15
Assay Id: MGI:5754408
Age: embryonic day 9.5
Image: 3C Pax1
Specimen Label: 3C Pax1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5754370
Assay Type: RNA in situ
Annotation Date: 2016-03-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116915
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:5754408
Age: embryonic day 9.5
Image: 3C Pax1
Specimen Label: 3C Pax1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:28160
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116914
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:6391093
Age: embryonic day 9.0
Image: 7A Pax1 E9 WT
Specimen Label: 7A Pax1 E9 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:28160
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6391093
Age: embryonic day 9.5
Image: 7A Pax1 E9.5 WT
Specimen Label: 7A Pax1 E9.5 WT
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:28160
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3116917
Stage: TS17
Assay Id: MGI:6391093
Age: embryonic day 10.5
Image: 7A Pax1 E10.5 Pbx1-/-;Pbx1-/-
Specimen Label: 7A Pax1 E10.5 Pbx1-/-;Pbx1-/-
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:28160
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3116917
Stage: TS17
Assay Id: MGI:6391093
Age: embryonic day 10.75
Image: 7A Pax1 E10.75 Pbx1-/-;Pbx1-/-
Specimen Label: 7A Pax1 E10.75 Pbx1-/-;Pbx1-/-
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:28160
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6391093
Age: embryonic day 10.5
Image: 7A Pax1 E10.5 WT
Specimen Label: 7A Pax1 E10.5 WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6436655
Assay Type: RT-PCR
Annotation Date: 2020-06-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3673015
Stage: TS15
Assay Id: MGI:6436692
Age: embryonic day 9.5
Image: 1
Specimen Label: Pax1
Detected: true
Specimen Num: 1
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Publication
25286939 | -
First Author: Narasimhan K
Year: 2014
Journal: Acta Crystallogr F Struct Biol Commun
Title: Crystallization and preliminary X-ray diffraction analysis of the Pax9 paired domain bound to a DC5 enhancer DNA element.
Volume: 70
Issue: Pt 10
Pages: 1357-61
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Publication
15950457 | -
First Author: Kozmik Z
Year: 2005
Journal: Curr Opin Genet Dev
Title: Pax genes in eye development and evolution.
Volume: 15
Issue: 4
Pages: 430-8
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Publication
24496612 | -
First Author: Blake JA
Year: 2014
Journal: Development
Title: Pax genes: regulators of lineage specification and progenitor cell maintenance.
Volume: 141
Issue: 4
Pages: 737-51
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Publication
14504237 | J:85847
First Author: Kokubu C
Year: 2003
Journal: Genetics
Title: Undulated short-tail deletion mutation in the mouse ablates Pax1 and leads to ectopic activation of neighboring Nkx2-2 in domains that normally express Pax1.
Volume: 165
Issue: 1
Pages: 299-307
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Gene
108228202 | LOC108228202
Type: gene
Organism: human
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Gene
108228200 | LOC108228200
Type: gene
Organism: human
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Protein
A2ALK0
Organism: Mus musculus/domesticus
Length: 384  
Fragment?: true
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Protein
P09084
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: false
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Protein
Q3UZ60
Organism: Mus musculus/domesticus
Length: 361  
Fragment?: false
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Publication
8565834 | J:30819
First Author: Wallin J
Year: 1996
Journal: Development
Title: Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation.
Volume: 122
Issue: 1
Pages: 23-30
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Publication
11900462 | J:75823
First Author: Aubin J
Year: 2002
Journal: Dev Biol
Title: Cooperation of Hoxa5 and Pax1 genes during formation of the pectoral girdle.
Volume: 244
Issue: 1
Pages: 96-113
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Publication
10556064 | J:44517
First Author: Peters H
Year: 1999
Journal: Development
Title: Pax1 and Pax9 synergistically regulate vertebral column development.
Volume: 126
Issue: 23
Pages: 5399-408
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Publication
9671740 | J:49339
First Author: Wilm B
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Targeted disruption of Pax1 defines its null phenotype and proves haploinsufficiency.
Volume: 95
Issue: 15
Pages: 8692-7
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Publication
11476574 | J:71183
First Author: Su D
Year: 2001
Journal: Dev Biol
Title: Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis.
Volume: 236
Issue: 2
Pages: 316-29
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GXD Expression
GXD Expression
   
Probe: MGI:5883231
Assay Type: RNA in situ
Annotation Date: 2017-04-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3115915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:5883248
Age: embryonic day 9.5
Specimen Label: 1B PAX1 E9.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5883231
Assay Type: RNA in situ
Annotation Date: 2017-04-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3115917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5883248
Age: embryonic day 10.5
Specimen Label: 1B PAX1 E10.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5883231
Assay Type: RNA in situ
Annotation Date: 2017-04-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3115919
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5883248
Age: embryonic day 11.5
Specimen Label: 1B PAX1 E11.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5883231
Assay Type: RNA in situ
Annotation Date: 2017-04-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752321
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5883248
Age: embryonic day 13.5
Specimen Label: 1C PAX1 E13.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:5883231
Assay Type: RNA in situ
Annotation Date: 2017-04-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3567620
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5883248
Age: embryonic day 12.5
Note: Expression in perichondrium of developing vertebral body, with peak expression at E12.5.
Specimen Label: 1B PAX1 E12.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5883231
Assay Type: RNA in situ
Annotation Date: 2017-04-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3567621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5883248
Age: embryonic day 13.5
Note: Expression in perichondrium of developing vertebral body.
Specimen Label: 1B PAX1 E13.5
Detected: true
Specimen Num: 5
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Publication
8535079 | J:29091
First Author: Otsen M
Year: 1995
Journal: Mamm Genome
Title: Assignment of the paired box gene Pax1 to rat chromosome 3.
Volume: 6
Issue: 9
Pages: 666-7
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Publication
10364424 | J:55575
First Author: Furumoto TA
Year: 1999
Journal: Dev Biol
Title: Notochord-dependent expression of MFH1 and PAX1 cooperates to maintain the proliferation of sclerotome cells during the vertebral column development.
Volume: 210
Issue: 1
Pages: 15-29
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Publication
10820253 | J:62238
First Author: Su DM
Year: 2000
Journal: J Immunol
Title: Hoxa3 and pax1 transcription factors regulate the ability of fetal thymic epithelial cells to promote thymocyte development.
Volume: 164
Issue: 11
Pages: 5753-60
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GXD Expression
GXD Expression
     
Probe: MGI:6180098
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191019
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pax1
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6180098
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6191019
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pax1
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6180098
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6191019
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pax1
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6180098
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6191019
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pax1
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6180098
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191019
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pax1
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6180098
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191019
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pax1
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:6180098
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191019
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pax1
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:6403312
Assay Type: RNA in situ
Annotation Date: 2020-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3115919
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6403315
Age: embryonic day 11.5
Image: 5H
Note: There was no detectable difference in Pax1 expression between wild type and mutant embryos.
Specimen Label: 5H
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1333908
Assay Type: Immunohistochemistry
Annotation Date: 1999-07-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3114419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:1339565
Age: embryonic day 11.5
Image: 1.Q,R
Note: Pax1 and Fkh14 (Mfh1) are coexpressed in sclerotome cells in the ventrolateral region.
Specimen Label: 1.Q,R
Detected: true
Specimen Num: 1
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Publication
28011632 | J:239547
First Author: Sivakamasundari V
Year: 2017
Journal: Biol Open
Title: A developmental transcriptomic analysis of Pax1 and Pax9 in embryonic intervertebral disc development.
Volume: 6
Issue: 2
Pages: 187-199
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GXD Expression
GXD Expression
Probe: MGI:1333908
Assay Type: Immunohistochemistry
Annotation Date: 1999-04-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3115122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:1334713
Age: embryonic day 14.5
Image: 7H
Note: In mutant embryos, the lateral lumbosacral sclerotome domains are altered and dense layers of cells expressing Pax1 are found surrounding the spinal nerve.
Specimen Label: 7H
Detected: true
Specimen Num: 9
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Protein
Q8K4Q2
Organism: Mus musculus/domesticus
Length: 88  
Fragment?: true
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Publication
16093716 | J:100951
First Author: Adham IM
Year: 2005
Journal: Cytogenet Genome Res
Title: The scoliosis (sco) mouse: a new allele of Pax1.
Volume: 111
Issue: 1
Pages: 16-26
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Publication
1889089 | J:31264
First Author: Chalepakis G
Year: 1991
Journal: Cell
Title: The molecular basis of the undulated/Pax-1 mutation.
Volume: 66
Issue: 5
Pages: 873-84
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Publication
- | J:314
First Author: Wright ME
Year: 1947
Journal: Heredity
Title: Undulated: a new genetic factor in Mus musculus affecting the spine and tail.
Volume: 1
Issue: 1
Pages: 137-41
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Publication
24538930 | J:13037
First Author: GRUNEBERG H
Year: 1950
Journal: J Genet
Title: Genetical studies on the skeleton of the mouse. II. Undulated and its 'modifiers'.
Volume: 50
Issue: 1
Pages: 142-73
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Publication
10705344 | J:61387
First Author: Quondamatteo F
Year: 2000
Journal: Anat Rec
Title: Extensive glycosylation changes revealed by lectin histochemistry in morphologically normal prenatal tissues of the mouse mutant undulated (un/un).
Volume: 258
Issue: 3
Pages: 243-51
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Publication
7649395 | J:28311
First Author: Neubüser A
Year: 1995
Journal: Dev Biol
Title: Characterization and developmental expression of Pax9, a paired-box-containing gene related to Pax1.
Volume: 170
Issue: 2
Pages: 701-16
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Publication
16315099 | J:103567
First Author: Joosten PH
Year: 2005
Journal: Transgenic Res
Title: Pax1/E2a double-mutant mice develop non-lethal neural tube defects that resemble human malformations.
Volume: 14
Issue: 6
Pages: 983-7
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Publication
10656775 | J:60410
First Author: Bialek P
Year: 2000
Journal: Dev Biol
Title: Characterization of a novel insertional mouse mutation, kkt: A closely linked modifier of Pax1.
Volume: 218
Issue: 2
Pages: 354-66
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Publication
3180219 | J:9424
First Author: Balling R
Year: 1988
Journal: Cell
Title: undulated, a mutation affecting the development of the mouse skeleton, has a point mutation in the paired box of Pax 1.
Volume: 55
Issue: 3
Pages: 531-5
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Publication
- | J:13467
 
First Author: Blandova ZK
Year: 1967
Journal: Mouse News Lett
Title: Un
Volume: 36
Pages: 57
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Publication
- | J:224656
     
First Author: Choi JH
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for wavy
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Publication
8026324 | J:18196
First Author: Wallin J
Year: 1994
Journal: Development
Title: The role of Pax-1 in axial skeleton development.
Volume: 120
Issue: 5
Pages: 1109-21
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Publication
- | J:13676
 
First Author: Blandova ZK
Year: 1975
Journal: Mouse News Lett
Title: Sut allelic with un
Volume: 52
Pages: 43
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Publication
9719926 | J:48723
First Author: Sakharova NIu
Year: 1998
Journal: Genetika
Title: [Non-Mendelian inheritance of the Un(s) mutant gene in mice].
Volume: 34
Issue: 6
Pages: 816-24
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Publication
- | J:13667
 
First Author: Ferguson JM
Year: 1975
Journal: Mouse News Lett
Title: cy linkage.
Volume: 52
Pages: 31
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Publication
8358169 | J:12925
First Author: Wallin J
Year: 1993
Journal: Mamm Genome
Title: A new Pax gene, Pax-9, maps to mouse chromosome 12.
Volume: 4
Issue: 7
Pages: 354-8
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Publication
8187635 | J:16332
First Author: Koseki H
Year: 1993
Journal: Development
Title: A role for Pax-1 as a mediator of notochordal signals during the dorsoventral specification of vertebrae.
Volume: 119
Issue: 3
Pages: 649-60
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Publication
7550316 | J:28396
First Author: Helwig U
Year: 1995
Journal: Nat Genet
Title: Interaction between undulated and Patch leads to an extreme form of spina bifida in double-mutant mice.
Volume: 11
Issue: 1
Pages: 60-3
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Publication
19633672 | J:151776
First Author: Kokubu C
Year: 2009
Journal: Nat Genet
Title: A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice.
Volume: 41
Issue: 8
Pages: 946-52
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Publication
7875377 | J:23331
First Author: Dietrich S
Year: 1995
Journal: Dev Biol
Title: undulated phenotypes suggest a role of Pax-1 for the development of vertebral and extravertebral structures.
Volume: 167
Issue: 2
Pages: 529-48
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Publication
- | J:13043
First Author: Gruneberg H
Year: 1954
Journal: J Genet
Title: Genetical studies on the skeleton of the mouse. XII. The development of undulated.
Volume: 52
Issue: 2
Pages: 441-455
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Publication
24514266 | J:208423
 
First Author: Stafford DA
Year: 2014
Journal: Mech Dev
Title: Follistatin interacts with Noggin in the development of the axial skeleton.
Volume: 131
Pages: 78-85
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Publication
1358810 | J:3073
First Author: Schnittger S
Year: 1992
Journal: Genomics
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