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Search results 1 to 100 out of 1144 for Pax5

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Type Details Score
Gene
5079 | PAX5
Type: gene
Organism: human
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Gene
500453 | Pax5
Type: gene
Organism: rat
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Gene
538371 | PAX5
Type: gene
Organism: cattle
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Gene
387330 | PAX5
Type: gene
Organism: chicken
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Gene
60636 | pax5
Type: gene
Organism: zebrafish
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Gene
716839 | PAX5
Type: gene
Organism: macaque, rhesus
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Gene
100493222 | pax5
Type: gene
Organism: frog, western clawed
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Gene
612021 | PAX5
Type: gene
Organism: dog, domestic
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Gene
747452 | PAX5
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:97489 | Pax5
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
108254682 | LOC108254682
Type: gene
Organism: human
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GXD Expression
GXD Expression
Probe: MGI:1345492
Assay Type: RNA in situ
Annotation Date: 1999-12-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:1349190
Age: embryonic day 9.5
Image: 6O Pax5 wild type
Note: Expression spans the caudal midbrain and the rostral hindbrain. These results are shown schematically in Fig. 8.
Specimen Label: 6O Pax5 wild type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7492074
Assay Type: RNA in situ
Annotation Date: 2023-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7492123
Age: embryonic day 10.5
Image: S2 pax5 +/+
Specimen Label: S2 pax5 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7492074
Assay Type: RNA in situ
Annotation Date: 2023-06-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7492123
Age: embryonic day 10.5
Image: S2 pax5 -/-
Note: Authors report non-aberrant expression pattern.
Specimen Label: S2 pax5 -/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1345492
Assay Type: RNA in situ
Annotation Date: 1999-12-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:1349190
Age: embryonic day 9.5
Image: 6O Pax5 wild type
Note: Expression spans the caudal midbrain and the rostral hindbrain. These results are shown schematically in Fig. 8.
Specimen Label: 6O Pax5 wild type
Detected: true
Specimen Num: 1
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Gene
108254684 | LOC108254684
Type: gene
Organism: human
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Publication
10192389 | J:54106
First Author: Nutt SL
Year: 1999
Journal: Nat Genet
Title: Independent regulation of the two Pax5 alleles during B-cell development.
Volume: 21
Issue: 4
Pages: 390-5
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Publication
16618805 | J:108330
First Author: Holmes ML
Year: 2006
Journal: Genes Dev
Title: Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment.
Volume: 20
Issue: 8
Pages: 933-8
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Publication
12098702 | J:129163
First Author: Mikkola I
Year: 2002
Journal: Science
Title: Reversion of B cell commitment upon loss of Pax5 expression.
Volume: 297
Issue: 5578
Pages: 110-3
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Publication
25855603 | J:224649
First Author: Dang J
Year: 2015
Journal: Blood
Title: PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia.
Volume: 125
Issue: 23
Pages: 3609-17
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Publication
- | J:306017
     
First Author: Boast B
Year: 2021
Journal: bioRxiv
Title: Dysregulation of PAX5 causes uncommittedB cell development and tumorigenesisin mice.
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Publication
16482219 | J:106689
First Author: Tagoh H
Year: 2006
Journal: EMBO J
Title: The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction.
Volume: 25
Issue: 5
Pages: 1070-80
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Publication
29490943 | J:262298
First Author: Martín-Lorenzo A
Year: 2018
Journal: Cancer Res
Title: Loss of Pax5 Exploits Sca1-BCR-ABLp190 Susceptibility to Confer the Metabolic Shift Essential for pB-ALL.
Volume: 78
Issue: 10
Pages: 2669-2679
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Publication
9705955 | J:110957
First Author: Thévenin C
Year: 1998
Journal: J Exp Med
Title: Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis.
Volume: 188
Issue: 4
Pages: 735-44
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Publication
33154497 | J:300414
First Author: Isidro-Hernández M
Year: 2020
Journal: Sci Rep
Title: Inhibition of inflammatory signaling in Pax5 mutant cells mitigates B-cell leukemogenesis.
Volume: 10
Issue: 1
Pages: 19189
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Publication
9159136 | J:40910
First Author: Urbánek P
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Cooperation of Pax2 and Pax5 in midbrain and cerebellum development.
Volume: 94
Issue: 11
Pages: 5703-8
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Publication
10934015 | J:63683
First Author: Bouchard M
Year: 2000
Journal: Development
Title: Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development.
Volume: 127
Issue: 17
Pages: 3703-13
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Publication
26056231 | J:226364
First Author: Ungerbäck J
Year: 2015
Journal: J Exp Med
Title: Combined heterozygous loss of Ebf1 and Pax5 allows for T-lineage conversion of B cell progenitors.
Volume: 212
Issue: 7
Pages: 1109-23
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Publication
24939936 | J:211775
First Author: Liu GJ
Year: 2014
Journal: Genes Dev
Title: Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia.
Volume: 28
Issue: 12
Pages: 1337-50
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Publication
33672551 | J:311648
 
First Author: Yu J
Year: 2021
Journal: Int J Mol Sci
Title: Pax5 Negatively Regulates Osteoclastogenesis through Downregulation of Blimp1.
Volume: 22
Issue: 4
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Publication
12479824 | J:80815
First Author: Souabni A
Year: 2002
Journal: Immunity
Title: Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1.
Volume: 17
Issue: 6
Pages: 781-93
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Publication
30089192 | J:266478
First Author: Grundström C
Year: 2018
Journal: Eur J Immunol
Title: ETS1 and PAX5 transcription factors recruit AID to Igh DNA.
Volume: 48
Issue: 10
Pages: 1687-1697
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Publication
25838350 | J:224653
First Author: Prasad MA
Year: 2015
Journal: Blood
Title: Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency.
Volume: 125
Issue: 26
Pages: 4052-9
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Publication
16680144 | J:112673
First Author: Zhang Z
Year: 2006
Journal: Nat Immunol
Title: Transcription factor Pax5 (BSAP) transactivates the RAG-mediated V(H)-to-DJ(H) rearrangement of immunoglobulin genes.
Volume: 7
Issue: 6
Pages: 616-24
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Publication
9042861 | J:38813
First Author: Nutt SL
Year: 1997
Journal: Genes Dev
Title: Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.
Volume: 11
Issue: 4
Pages: 476-91
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Publication
21552207 | J:173158
First Author: McManus S
Year: 2011
Journal: EMBO J
Title: The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells.
Volume: 30
Issue: 12
Pages: 2388-404
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Publication
17671180 | J:123916
First Author: Balasenthil S
Year: 2007
Journal: Cancer Res
Title: Identification of Pax5 as a target of MTA1 in B-cell lymphomas.
Volume: 67
Issue: 15
Pages: 7132-8
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Publication
16968900 | J:118111
First Author: Souabni A
Year: 2007
Journal: Blood
Title: Oncogenic role of Pax5 in the T-lymphoid lineage upon ectopic expression from the immunoglobulin heavy-chain locus.
Volume: 109
Issue: 1
Pages: 281-9
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Publication
10662641 | J:60092
First Author: Pfeffer PL
Year: 2000
Journal: Development
Title: Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the midbrain-hindbrain boundary.
Volume: 127
Issue: 5
Pages: 1017-28
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Publication
15356142 | J:92741
First Author: Höflinger S
Year: 2004
Journal: J Immunol
Title: Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors.
Volume: 173
Issue: 6
Pages: 3935-44
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Publication
32612238 | J:294166
First Author: Hill L
Year: 2020
Journal: Nature
Title: Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion.
Volume: 584
Issue: 7819
Pages: 142-147
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Publication
19345119 | J:147974
First Author: Decker T
Year: 2009
Journal: Immunity
Title: Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis.
Volume: 30
Issue: 4
Pages: 508-20
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Publication
21349430 | J:168973
First Author: Ebert A
Year: 2011
Journal: Immunity
Title: The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells.
Volume: 34
Issue: 2
Pages: 175-87
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Publication
17658281 | J:123629
First Author: Schebesta A
Year: 2007
Journal: Immunity
Title: Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function.
Volume: 27
Issue: 1
Pages: 49-63
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Publication
22669466 | J:216790
First Author: Revilla-I-Domingo R
Year: 2012
Journal: EMBO J
Title: The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis.
Volume: 31
Issue: 14
Pages: 3130-46
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Publication
15007090 | J:90482
First Author: Hsu LY
Year: 2004
Journal: J Exp Med
Title: Pax5 activates immunoglobulin heavy chain V to DJ rearrangement in transgenic thymocytes.
Volume: 199
Issue: 6
Pages: 825-30
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Publication
11477548 | J:70486
First Author: Steinbach JP
Year: 2001
Journal: Int J Cancer
Title: Overexpression of Pax5 is not sufficient for neoplastic transformation of mouse neuroectoderm.
Volume: 93
Issue: 4
Pages: 459-67
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Publication
12514097 | J:81181
First Author: Hesslein DG
Year: 2003
Journal: Genes Dev
Title: Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments.
Volume: 17
Issue: 1
Pages: 37-42
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Publication
37725138 | J:340763
 
First Author: Gruenbacher S
Year: 2023
Journal: J Exp Med
Title: Essential role of the Pax5 C-terminal domain in controlling B cell commitment and development.
Volume: 220
Issue: 12
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GXD Expression
GXD Expression
 
Probe: MGI:3583711
Assay Type: RNA in situ
Annotation Date: 2005-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614814
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:3586674
Age: embryonic day 9.5
Image: S3B Pax5 +/-
Specimen Label: S3B Pax5 +/-
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:3583711
Assay Type: RNA in situ
Annotation Date: 2005-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3586674
Age: embryonic day 9.5
Image: S3B Pax5 -/-
Note: As in wild type, expression was detected in the mid-hindbrain region.
Specimen Label: S3B Pax5 -/-
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:3583711
Assay Type: RNA in situ
Annotation Date: 2005-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614014
Pattern: Not Specified
Stage: TS14
Assay Id: MGI:3586674
Age: embryonic day 9.5
Image: S3B Pax5 +/-
Specimen Label: S3B Pax5 +/-
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:3583711
Assay Type: RNA in situ
Annotation Date: 2005-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:3586674
Age: embryonic day 9.5
Image: S3B Pax5 -/-
Note: As in wild type, expression was detected in the mid-hindbrain region.
Specimen Label: S3B Pax5 -/-
Detected: true
Specimen Num: 9
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Publication
16546096 | J:113322
First Author: Delogu A
Year: 2006
Journal: Immunity
Title: Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.
Volume: 24
Issue: 3
Pages: 269-81
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Publication
14581609 | J:86463
First Author: Gonda H
Year: 2003
Journal: J Exp Med
Title: The balance between Pax5 and Id2 activities is the key to AID gene expression.
Volume: 198
Issue: 9
Pages: 1427-37
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Publication
33619557 | J:343860
First Author: Somasundaram R
Year: 2021
Journal: Blood
Title: EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene.
Volume: 137
Issue: 22
Pages: 3037-3049
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Publication
11799127 | J:114021
First Author: Emelyanov AV
Year: 2002
Journal: J Biol Chem
Title: The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells.
Volume: 277
Issue: 13
Pages: 11156-64
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Publication
18812467 | J:144261
First Author: Rafei M
Year: 2008
Journal: Blood
Title: Mesenchymal stromal cell-derived CCL2 suppresses plasma cell immunoglobulin production via STAT3 inactivation and PAX5 induction.
Volume: 112
Issue: 13
Pages: 4991-8
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Publication
17312149 | J:144100
First Author: Fuxa M
Year: 2007
Journal: J Immunol
Title: Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function.
Volume: 178
Issue: 5
Pages: 3031-7
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GXD Expression
GXD Expression
   
Probe: MGI:6180104
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191023
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pax5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6180104
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191023
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pax5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6180104
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191023
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pax5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6180104
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191023
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pax5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6180104
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191023
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pax5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6180104
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191023
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pax5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6180104
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191023
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pax5
Detected: true
Specimen Num: 7
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Publication
16407117 | J:105665
First Author: Hsu CL
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Antagonistic effect of CCAAT enhancer-binding protein-alpha and Pax5 in myeloid or lymphoid lineage choice in common lymphoid progenitors.
Volume: 103
Issue: 3
Pages: 672-7
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Publication
7777508 | J:26236
First Author: Neurath MF
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Pax5 (BSAP) regulates the murine immunoglobulin 3' alpha enhancer by suppressing binding of NF-alpha P, a protein that controls heavy chain transcription.
Volume: 92
Issue: 12
Pages: 5336-40
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Publication
18644860 | J:140359
First Author: Giambra V
Year: 2008
Journal: Mol Cell Biol
Title: Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3' regulatory region of the immunoglobulin heavy chain locus.
Volume: 28
Issue: 19
Pages: 6123-33
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Publication
10524622 | J:58040
First Author: Nutt SL
Year: 1999
Journal: Nature
Title: Commitment to the B-lymphoid lineage depends on the transcription factor Pax5.
Volume: 401
Issue: 6753
Pages: 556-62
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DO Term
DOID:0081411 | B acute lymphoblastic leukemia with PAX5 P80R mutation
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Publication
8790871 | J:113076
First Author: Reimer K
Year: 1996
Journal: Audiology
Title: Normal brainstem auditory evoked potentials in Pax5-deficient mice despite morphologic alterations in the auditory midbrain region.
Volume: 35
Issue: 1
Pages: 55-61
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Publication
8001127 | J:21935
First Author: Urbánek P
Year: 1994
Journal: Cell
Title: Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP.
Volume: 79
Issue: 5
Pages: 901-12
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Publication
35131871 | J:321830
First Author: Casado-García A
Year: 2022
Journal: Cancer Res
Title: Transient Inhibition of the JAK/STAT Pathway Prevents B-ALL Development in Genetically Predisposed Mice.
Volume: 82
Issue: 6
Pages: 1098-1109
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Publication
22927250 | J:192936
First Author: Simmons S
Year: 2012
Journal: Blood
Title: Biphenotypic B-lymphoid/myeloid cells expressing low levels of Pax5: potential targets of BAL development.
Volume: 120
Issue: 18
Pages: 3688-98
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Publication
22807655 | J:190068
First Author: Demczuk A
Year: 2012
Journal: PLoS Biol
Title: Regulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitment.
Volume: 10
Issue: 7
Pages: e1001360
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Publication
26408659 | J:231491
First Author: Martín-Lorenzo A
Year: 2015
Journal: Cancer Discov
Title: Infection Exposure is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility.
Volume: 5
Issue: 12
Pages: 1328-43
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Publication
30643249 | J:270049
First Author: Gu Z
Year: 2019
Journal: Nat Genet
Title: PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia.
Volume: 51
Issue: 2
Pages: 296-307
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Publication
27913602 | J:237409
First Author: Somasundaram R
Year: 2016
Journal: Genes Dev
Title: Clonal conversion of B lymphoid leukemia reveals cross-lineage transfer of malignant states.
Volume: 30
Issue: 22
Pages: 2486-2499
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Publication
24078629 | J:204995
First Author: Åhsberg J
Year: 2013
Journal: J Biol Chem
Title: Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner.
Volume: 288
Issue: 46
Pages: 33449-61
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Publication
17111353 | J:117084
First Author: Carotta S
Year: 2006
Journal: Eur J Immunol
Title: Transient Notch signaling induces NK cell potential in Pax5-deficient pro-B cells.
Volume: 36
Issue: 12
Pages: 3294-304
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Publication
15557148 | J:94372
First Author: Horowitz MC
Year: 2004
Journal: J Immunol
Title: Pax5-deficient mice exhibit early onset osteopenia with increased osteoclast progenitors.
Volume: 173
Issue: 11
Pages: 6583-91
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