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Search results 1 to 100 out of 1030 for Pax8

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0.019s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression  
Probe: MGI:5000874
Assay Type: RNA in situ
Annotation Date: 2013-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2775623
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5448145
Age: embryonic day 15.5
Image: 3A Pax8
Specimen Label: 3A Pax8
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5000874
Assay Type: RNA in situ
Annotation Date: 2013-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2767823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5448145
Age: embryonic day 15.5
Image: 6 Pax8
Specimen Label: 6 Pax8
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7571530
Assay Type: Immunohistochemistry
Annotation Date: 2024-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3675817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7571564
Age: embryonic day 10.5
Image: 9E Pax8
Note: Virtually all expressing cells senescent placode cells in epibranchial placode 2 are predominantly weakly Pax8-expressing progenitors.
Specimen Label: 9E Pax8
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5000874
Assay Type: RNA in situ
Annotation Date: 2013-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2775623
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5448145
Age: embryonic day 15.5
Image: 6 Pax8
Specimen Label: 6 Pax8
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5000874
Assay Type: RNA in situ
Annotation Date: 2013-01-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2767823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5448145
Age: embryonic day 15.5
Image: 3A Pax8
Specimen Label: 3A Pax8
Detected: true
Specimen Num: 1
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Bouchard M
Year: 2004
Journal: Genesis
Title: Tissue-specific expression of cre recombinase from the Pax8 locus.
Volume: 38
Issue: 3
Pages: 105-9
Publication
First Author: Bouchard M
Year: 2002
Journal: Genes Dev
Title: Nephric lineage specification by Pax2 and Pax8.
Volume: 16
Issue: 22
Pages: 2958-70
GXD Expression    
Probe: MGI:7578917
Assay Type: RNA in situ
Annotation Date: 2024-01-30
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7578921
Age: embryonic day 13.5
Specimen Label: S7e Pax8
Detected: true
Specimen Num: 1
Publication
First Author: Damante G
Year: 1998
Journal: Eur J Endocrinol
Title: Thyroid defects due to Pax8 gene mutations.
Volume: 139
Issue: 6
Pages: 563-6
Publication
First Author: Mansouri A
Year: 1998
Journal: Nat Genet
Title: Follicular cells of the thyroid gland require Pax8 gene function.
Volume: 19
Issue: 1
Pages: 87-90
Publication
First Author: Marotta P
Year: 2014
Journal: Mol Cell Endocrinol
Title: The paired box transcription factor Pax8 is essential for function and survival of adult thyroid cells.
Volume: 396
Issue: 1-2
Pages: 26-36
Publication
First Author: Di Palma T
Year: 2003
Journal: J Biol Chem
Title: The paired domain-containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcription.
Volume: 278
Issue: 5
Pages: 3395-402
Publication  
First Author: Bouchard M
Year: 2010
Journal: BMC Dev Biol
Title: Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation.
Volume: 10
Pages: 89
Publication
First Author: de Cristofaro T
Year: 2012
Journal: Mol Endocrinol
Title: An essential role for Pax8 in the transcriptional regulation of cadherin-16 in thyroid cells.
Volume: 26
Issue: 1
Pages: 67-78
Publication
First Author: Christ S
Year: 2004
Journal: Audiol Neurootol
Title: Hearing loss in athyroid pax8 knockout mice and effects of thyroxine substitution.
Volume: 9
Issue: 2
Pages: 88-106
Publication
First Author: Di Palma T
Year: 2009
Journal: Exp Cell Res
Title: TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation.
Volume: 315
Issue: 2
Pages: 162-75
Publication
First Author: Wu Y
Year: 2016
Journal: J Cell Mol Med
Title: Pax8 plays a pivotal role in regulation of cardiomyocyte growth and senescence.
Volume: 20
Issue: 4
Pages: 644-54
Publication
First Author: Narlis M
Year: 2007
Journal: J Am Soc Nephrol
Title: Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney.
Volume: 18
Issue: 4
Pages: 1121-9
Publication
First Author: Glaschke A
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: Developmental changes of cone opsin expression but not retinal morphology in the hypothyroid Pax8 knockout mouse.
Volume: 51
Issue: 3
Pages: 1719-27
Publication
First Author: Pfeffer PL
Year: 1998
Journal: Development
Title: Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function.
Volume: 125
Issue: 16
Pages: 3063-74
Publication  
First Author: Fu DJ
Year: 2020
Journal: Dis Model Mech
Title: Cells expressing PAX8 are the main source of homeostatic regeneration of adult mouse endometrial epithelium and give rise to serous endometrial carcinoma.
Volume: 13
Issue: 10
GXD Expression    
Probe: MGI:6180112
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191026
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pax8
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6180112
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191026
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pax8
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6180112
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191026
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pax8
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6180112
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191026
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pax8
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6180112
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191026
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pax8
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6180112
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191026
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pax8
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6180112
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191026
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pax8
Detected: true
Specimen Num: 7
Publication
First Author: Martin-Montalvo A
Year: 2019
Journal: Diabetes
Title: Transient PAX8 Expression in Islets During Pregnancy Correlates With β-Cell Survival, Revealing a Novel Candidate Gene in Gestational Diabetes Mellitus.
Volume: 68
Issue: 1
Pages: 109-118
Publication  
First Author: Albano F
Year: 2021
Journal: Int J Mol Sci
Title: ZFP36L2 Role in Thyroid Functionality.
Volume: 22
Issue: 17
Publication
First Author: Iervolino A
Year: 2015
Journal: PLoS One
Title: Selective dicer suppression in the kidney alters GSK3β/β-catenin pathways promoting a glomerulocystic disease.
Volume: 10
Issue: 3
Pages: e0119142
Publication  
First Author: Bartram MP
Year: 2016
Journal: BMC Mol Biol
Title: Mice lacking microRNAs in Pax8-expressing cells develop hypothyroidism and end-stage renal failure.
Volume: 17
Pages: 11
Publication
First Author: Koumarianou P
Year: 2017
Journal: J Cell Sci
Title: Pax8 controls thyroid follicular polarity through cadherin-16.
Volume: 130
Issue: 1
Pages: 219-231
Publication
First Author: Verissimo T
Year: 2023
Journal: Am J Physiol Renal Physiol
Title: PCK1 is a key regulator of metabolic and mitochondrial functions in renal tubular cells.
Volume: 324
Issue: 6
Pages: F532-F543
Publication
First Author: Cullen PF
Year: 2024
Journal: Glia
Title: Transcriptional profiling of retinal astrocytes identifies a specific marker and points to functional specialization.
Volume: 72
Issue: 9
Pages: 1604-1628
Publication  
First Author: Iervolino A
Year: 2018
Journal: Front Physiol
Title: Integrin Beta 1 Is Crucial for Urinary Concentrating Ability and Renal Medulla Architecture in Adult Mice.
Volume: 9
Pages: 1273
Publication
First Author: Zhao XP
Year: 2023
Journal: Diabetologia
Title: Hedgehog interacting protein activates sodium-glucose cotransporter 2 expression and promotes renal tubular epithelial cell senescence in a mouse model of type 1 diabetes.
Volume: 66
Issue: 1
Pages: 223-240
Publication
First Author: Lo CS
Year: 2019
Journal: Sci Rep
Title: Tubular Deficiency of Heterogeneous Nuclear Ribonucleoprotein F Elevates Systolic Blood Pressure and Induces Glycosuria in Mice.
Volume: 9
Issue: 1
Pages: 15765
Publication
First Author: Fenton RA
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3.
Volume: 308
Issue: 12
Pages: F1409-20
Publication
First Author: Fenton RA
Year: 2017
Journal: Kidney Int
Title: Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis.
Volume: 92
Issue: 2
Pages: 397-414
Publication
First Author: Reale C
Year: 2016
Journal: J Biol Chem
Title: NF-κB Essential Modulator (NEMO) Is Critical for Thyroid Function.
Volume: 291
Issue: 11
Pages: 5765-73
Publication
First Author: Harris AN
Year: 2021
Journal: Am J Physiol Renal Physiol
Title: Role of the renal androgen receptor in sex differences in ammonia metabolism.
Volume: 321
Issue: 5
Pages: F629-F644
Publication
First Author: Lee HW
Year: 2022
Journal: Am J Physiol Renal Physiol
Title: Acid-base effects of combined renal deletion of NBCe1-A and NBCe1-B.
Volume: 322
Issue: 2
Pages: F208-F224
Publication
First Author: Marsching C
Year: 2014
Journal: J Lipid Res
Title: Quantitative imaging mass spectrometry of renal sulfatides: validation by classical mass spectrometric methods.
Volume: 55
Issue: 11
Pages: 2343-53
Publication
First Author: Hayashi S
Year: 2011
Journal: Mol Biol Evol
Title: Lack of in vivo functional compensation between Pax family groups II and III in rodents.
Volume: 28
Issue: 10
Pages: 2787-98
Publication
First Author: Stransky LA
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: Toward a CRISPR-based mouse model of Vhl-deficient clear cell kidney cancer: Initial experience and lessons learned.
Volume: 121
Issue: 41
Pages: e2408549121
Publication
First Author: Mittag J
Year: 2007
Journal: Endocrinology
Title: Congenital hypothyroid female pax8-deficient mice are infertile despite thyroid hormone replacement therapy.
Volume: 148
Issue: 2
Pages: 719-25
Protein
Organism: Mus musculus/domesticus
Length: 251  
Fragment?: true
Publication
First Author: Antonica F
Year: 2012
Journal: Nature
Title: Generation of functional thyroid from embryonic stem cells.
Volume: 491
Issue: 7422
Pages: 66-71
Publication
First Author: Grieco G
Year: 2018
Journal: Sci Rep
Title: Vps34/PI3KC3 deletion in kidney proximal tubules impairs apical trafficking and blocks autophagic flux, causing a Fanconi-like syndrome and renal insufficiency.
Volume: 8
Issue: 1
Pages: 14133
Publication
First Author: Possik E
Year: 2015
Journal: PLoS Genet
Title: FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores.
Volume: 11
Issue: 10
Pages: e1005520
Publication
First Author: Poleev A
Year: 1992
Journal: Development
Title: PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors.
Volume: 116
Issue: 3
Pages: 611-23
Publication
First Author: Dalghi MG
Year: 2024
Journal: Physiol Rep
Title: Expression and localization of the mechanosensitive/osmosensitive ion channel TMEM63B in the mouse urinary tract.
Volume: 12
Issue: 9
Pages: e16043
Publication  
First Author: Prakasam G
Year: 2024
Journal: J Clin Invest
Title: Comparative genomics incorporating translocation renal cell carcinoma mouse model reveals molecular mechanisms of tumorigenesis.
Volume: 134
Issue: 7
Publication
First Author: Ford MJ
Year: 2021
Journal: Cell Rep
Title: Oviduct epithelial cells constitute two developmentally distinct lineages that are spatially separated along the distal-proximal axis.
Volume: 36
Issue: 10
Pages: 109677
Publication
First Author: Nørgård MØ
Year: 2022
Journal: Sci Rep
Title: A new transgene mouse model using an extravesicular EGFP tag enables affinity isolation of cell-specific extracellular vesicles.
Volume: 12
Issue: 1
Pages: 496
Publication
First Author: Ziros PG
Year: 2018
Journal: Thyroid
Title: NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland.
Volume: 28
Issue: 6
Pages: 780-798
Publication
First Author: Poulsen SB
Year: 2018
Journal: Clin Sci (Lond)
Title: Adenylyl cyclase 6 is required for maintaining acid-base homeostasis.
Volume: 132
Issue: 16
Pages: 1779-1796
Publication  
First Author: Collier JB
Year: 2024
Journal: Mol Metab
Title: GLIS3: A novel transcriptional regulator of mitochondrial functions and metabolic reprogramming in postnatal kidney and polycystic kidney disease.
Volume: 90
Pages: 102052
Publication
First Author: Hick AC
Year: 2013
Journal: Dev Biol
Title: Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation.
Volume: 381
Issue: 1
Pages: 227-40
Publication
First Author: Westerlund J
Year: 2008
Journal: Dev Dyn
Title: Expression of Islet1 in thyroid development related to budding, migration, and fusion of primordia.
Volume: 237
Issue: 12
Pages: 3820-9
Publication
First Author: Bassett JH
Year: 2008
Journal: Mol Endocrinol
Title: A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism.
Volume: 22
Issue: 2
Pages: 501-12
Publication
First Author: Reale C
Year: 2018
Journal: Sci Rep
Title: Genetic background and window of exposure contribute to thyroid dysfunction promoted by low-dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice.
Volume: 8
Issue: 1
Pages: 16324
Publication
First Author: D'Amico E
Year: 2013
Journal: J Mol Endocrinol
Title: Thyroid-specific inactivation of KIF3A alters the TSH signaling pathway and leads to hypothyroidism.
Volume: 50
Issue: 3
Pages: 375-87
Publication
First Author: Dehbi M
Year: 1996
Journal: EMBO J
Title: PAX8-mediated activation of the wt1 tumor suppressor gene.
Volume: 15
Issue: 16
Pages: 4297-306
Publication
First Author: Ni Y
Year: 2022
Journal: Int J Biol Sci
Title: Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation.
Volume: 18
Issue: 13
Pages: 5168-5184
Publication
First Author: Spina A
Year: 2011
Journal: Anat Rec (Hoboken)
Title: Fate map of serotonin transporter-expressing cells in developing mouse thyroid.
Volume: 294
Issue: 3
Pages: 384-90
Publication
First Author: Trajkovic-Arsic M
Year: 2010
Journal: Endocrinology
Title: Impact of monocarboxylate transporter-8 deficiency on the hypothalamus-pituitary-thyroid axis in mice.
Volume: 151
Issue: 10
Pages: 5053-62
Publication
First Author: Plachov D
Year: 1990
Journal: Development
Title: Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland.
Volume: 110
Issue: 2
Pages: 643-51
Publication
First Author: Kim YC
Year: 2023
Journal: Am J Physiol Renal Physiol
Title: Expression of leptin receptor in renal tubules is sparse but implicated in leptin-dependent kidney gene expression and function.
Volume: 324
Issue: 6
Pages: F544-F557
Publication
First Author: Wendl T
Year: 2002
Journal: Development
Title: Pax2.1 is required for the development of thyroid follicles in zebrafish.
Volume: 129
Issue: 15
Pages: 3751-60
Publication
First Author: Clarke JC
Year: 2006
Journal: Hum Mol Genet
Title: Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage.
Volume: 15
Issue: 23
Pages: 3420-8
Publication
First Author: Wistuba J
Year: 2007
Journal: J Endocrinol
Title: Male congenital hypothyroid Pax8-/- mice are infertile despite adequate treatment with thyroid hormone.
Volume: 192
Issue: 1
Pages: 99-109
Publication
First Author: Washausen S
Year: 2017
Journal: Brain Struct Funct
Title: Pax2/Pax8-defined subdomains and the occurrence of apoptosis in the posterior placodal area of mice.
Volume: 222
Issue: 6
Pages: 2671-2695
Publication  
First Author: Haerlingen B
Year: 2023
Journal: Development
Title: Mesodermal FGF and BMP govern the sequential stages of zebrafish thyroid specification.
Volume: 150
Issue: 10
Publication
First Author: Zhou L
Year: 2024
Journal: Sci Transl Med
Title: Glucocorticoids induce a maladaptive epithelial stress response to aggravate acute kidney injury.
Volume: 16
Issue: 767
Pages: eadk5005
Publication
First Author: Rodriguez W
Year: 2012
Journal: PLoS One
Title: Deletion of the RNaseIII enzyme dicer in thyroid follicular cells causes hypothyroidism with signs of neoplastic alterations.
Volume: 7
Issue: 1
Pages: e29929
Publication
First Author: Porubsky S
Year: 2014
Journal: J Pathol
Title: Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure.
Volume: 234
Issue: 1
Pages: 120-33
Publication
First Author: Kaminski MM
Year: 2016
Journal: Nat Cell Biol
Title: Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.
Volume: 18
Issue: 12
Pages: 1269-1280
Publication
First Author: Parlato R
Year: 2004
Journal: Dev Biol
Title: An integrated regulatory network controlling survival and migration in thyroid organogenesis.
Volume: 276
Issue: 2
Pages: 464-75
Publication
First Author: Amendola E
Year: 2005
Journal: Endocrinology
Title: A mouse model demonstrates a multigenic origin of congenital hypothyroidism.
Volume: 146
Issue: 12
Pages: 5038-47
Publication
First Author: Onishi A
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Effect of renal tubule-specific knockdown of the Na+/H+ exchanger NHE3 in Akita diabetic mice.
Volume: 317
Issue: 2
Pages: F419-F434
Publication
First Author: Asrani K
Year: 2022
Journal: Nat Commun
Title: An mTORC1-mediated negative feedback loop constrains amino acid-induced FLCN-Rag activation in renal cells with TSC2 loss.
Volume: 13
Issue: 1
Pages: 6808
Publication
First Author: Yu SM
Year: 2025
Journal: Am J Pathol
Title: A Newly Identified Protective Role of C5a Receptor 1 in Kidney Tubules against Toxin-Induced Acute Kidney Injury.
Volume: 195
Issue: 1
Pages: 126-142
Publication
First Author: Dobson ME
Year: 2011
Journal: Endocrinology
Title: Pioglitazone induces a proadipogenic antitumor response in mice with PAX8-PPARgamma fusion protein thyroid carcinoma.
Volume: 152
Issue: 11
Pages: 4455-65
Publication
First Author: Stettner P
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Sulfatides are required for renal adaptation to chronic metabolic acidosis.
Volume: 110
Issue: 24
Pages: 9998-10003
Publication      
First Author: Kulibin AY
Year: 2020
Journal: Dev Dyn
Title: Formation of the rete testis during mouse embryonic development.
Publication
First Author: Weiss RE
Year: 2002
Journal: J Endocrinol
Title: Thyroid function and effect of aging in combined hetero/homozygous mice deficient in thyroid hormone receptors alpha and beta genes.
Volume: 172
Issue: 1
Pages: 177-85
Publication
First Author: Frezzetti D
Year: 2011
Journal: PLoS One
Title: The microRNA-processing enzyme Dicer is essential for thyroid function.
Volume: 6
Issue: 11
Pages: e27648