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Search results 1 to 100 out of 930 for Pax9

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0.037s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: PAX9 belongs to the Pax family. It is essential to generate a pool of taste bud progenitors and to maintain their competence towards prosensory cell fate induction []. It is involved in palate []and tooth morphogenesis [].PAX family members are transcription factors characterised by a ~128-amino-acid DNA-binding paired domain that makes sequence specific contacts with DNA []. In mammals, there are nine Pax proteins (PAX1-9). They regulate the morphogenesis of a wide range of organs and are key factors for the development of mammalian sensory organs such as the eye (Pax6, Pax2), nose (Pax6) and ears (Pax2, Pax8) [, ].
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Nakatomi M
Year: 2010
Journal: Dev Biol
Title: Genetic interactions between Pax9 and Msx1 regulate lip development and several stages of tooth morphogenesis.
Volume: 340
Issue: 2
Pages: 438-49
Publication
First Author: Zhou J
Year: 2013
Journal: Development
Title: Pax9 regulates a molecular network involving Bmp4, Fgf10, Shh signaling and the Osr2 transcription factor to control palate morphogenesis.
Volume: 140
Issue: 23
Pages: 4709-18
Publication
First Author: Kist R
Year: 2014
Journal: PLoS Genet
Title: The formation of endoderm-derived taste sensory organs requires a Pax9-dependent expansion of embryonic taste bud progenitor cells.
Volume: 10
Issue: 10
Pages: e1004709
Gene
Type: gene
Organism: human
GXD Expression
Probe: MGI:7587796
Assay Type: RNA in situ
Annotation Date: 2024-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775621
Pattern: Ubiquitous
Stage: TS21
Assay Id: MGI:7587815
Age: embryonic day 13.0
Image: 1C Pax9
Note: Expression uniformly distributed.
Specimen Label: 1C Pax9
Detected: true
Specimen Num: 1
Publication
First Author: Narasimhan K
Year: 2014
Journal: Acta Crystallogr F Struct Biol Commun
Title: Crystallization and preliminary X-ray diffraction analysis of the Pax9 paired domain bound to a DC5 enhancer DNA element.
Volume: 70
Issue: Pt 10
Pages: 1357-61
GXD Expression  
Probe: MGI:1326918
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6391094
Age: embryonic day 10.5
Image: 7A Pax9 E10.5 WT
Specimen Label: 7A Pax9 E10.5 WT
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1326918
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:6391094
Age: embryonic day 9.5
Image: 7A Pax9 E9.5 WT
Specimen Label: 7A Pax9 E9.5 WT
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6436656
Assay Type: RT-PCR
Annotation Date: 2020-06-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3673015
Stage: TS15
Assay Id: MGI:6436693
Age: embryonic day 9.5
Image: 1
Specimen Label: Pax9
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1326918
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1675216
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:6391094
Age: embryonic day 10.0
Image: 7A Pax9 E10 Pbx1-/-;Pbx1-/- (left)
Note: Low levels of expression most caudally in pre-somitic mesoderm.
Specimen Label: 7A Pax9 E10 Pbx1-/-;Pbx1-/- (left)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1326918
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3116916
Stage: TS16
Assay Id: MGI:6391094
Age: embryonic day 10.0
Image: 7A Pax9 E10 Pbx1-/-;Pbx1-/- (right)
Specimen Label: 7A Pax9 E10 Pbx1-/-;Pbx1-/- (right)
Detected: false
Specimen Num: 4
GXD Expression
Probe: MGI:1326918
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1675216
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:6391094
Age: embryonic day 10.0
Image: 7A Pax9 E10 Pbx1-/-;Pbx1-/- (right)
Note: Low levels of expression most caudally in pre-somitic mesoderm.
Specimen Label: 7A Pax9 E10 Pbx1-/-;Pbx1-/- (right)
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1326918
Assay Type: RNA in situ
Annotation Date: 2020-02-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3116916
Stage: TS16
Assay Id: MGI:6391094
Age: embryonic day 10.0
Image: 7A Pax9 E10 Pbx1-/-;Pbx1-/- (left)
Specimen Label: 7A Pax9 E10 Pbx1-/-;Pbx1-/- (left)
Detected: false
Specimen Num: 3
Publication
First Author: Kozmik Z
Year: 2005
Journal: Curr Opin Genet Dev
Title: Pax genes in eye development and evolution.
Volume: 15
Issue: 4
Pages: 430-8
Publication
First Author: Blake JA
Year: 2014
Journal: Development
Title: Pax genes: regulators of lineage specification and progenitor cell maintenance.
Volume: 141
Issue: 4
Pages: 737-51
Protein
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
GXD Expression  
Probe: MGI:3506125
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3507620
Age: postnatal newborn
Note: Expression was detected in non-neural olfactory tissue.
Specimen Label: S8 Pax9
Detected: true
Specimen Num: 3
Publication  
First Author: Peters H
Year: 1998
Journal: Eur J Oral Sci
Title: Pax genes and organogenesis: Pax9 meets tooth development.
Volume: 106 Suppl 1
Pages: 38-43
Publication
First Author: Peters H
Year: 1999
Journal: Development
Title: Pax1 and Pax9 synergistically regulate vertebral column development.
Volume: 126
Issue: 23
Pages: 5399-408
Publication
First Author: Rodrigo I
Year: 2003
Journal: Development
Title: Pax1 and Pax9 activate Bapx1 to induce chondrogenic differentiation in the sclerotome.
Volume: 130
Issue: 3
Pages: 473-82
Publication
First Author: Hetzer-Egger C
Year: 2002
Journal: Eur J Immunol
Title: Thymopoiesis requires Pax9 function in thymic epithelial cells.
Volume: 32
Issue: 4
Pages: 1175-81
Publication
First Author: Sweat YY
Year: 2020
Journal: Dev Biol
Title: Six2 regulates Pax9 expression, palatogenesis and craniofacial bone formation.
Volume: 458
Issue: 2
Pages: 246-256
Publication
First Author: Li C
Year: 2017
Journal: J Dent Res
Title: Modulating Wnt Signaling Rescues Palate Morphogenesis in Pax9 Mutant Mice.
Volume: 96
Issue: 11
Pages: 1273-1281
Publication
First Author: Peters H
Year: 1997
Journal: Mamm Genome
Title: Isolation of the Pax9 cDNA from adult human esophagus.
Volume: 8
Issue: 1
Pages: 62-4
Publication
First Author: Xiong Z
Year: 2018
Journal: J Pathol
Title: PAX9 regulates squamous cell differentiation and carcinogenesis in the oro-oesophageal epithelium.
Volume: 244
Issue: 2
Pages: 164-175
Publication
First Author: Zhou J
Year: 2011
Journal: Dev Biol
Title: Osr2 acts downstream of Pax9 and interacts with both Msx1 and Pax9 to pattern the tooth developmental field.
Volume: 353
Issue: 2
Pages: 344-53
Publication
First Author: Kist R
Year: 2005
Journal: Hum Mol Genet
Title: Reduction of Pax9 gene dosage in an allelic series of mouse mutants causes hypodontia and oligodontia.
Volume: 14
Issue: 23
Pages: 3605-17
Publication
First Author: Hamachi T
Year: 2003
Journal: Arch Oral Biol
Title: Association between palatal morphogenesis and Pax9 expression pattern in CL/Fr embryos with clefting during palatal development.
Volume: 48
Issue: 8
Pages: 581-7
Publication
First Author: Mensah JK
Year: 2004
Journal: J Biol Chem
Title: Functional analysis of a mutation in PAX9 associated with familial tooth agenesis in humans.
Volume: 279
Issue: 7
Pages: 5924-33
Publication
First Author: McGlinn E
Year: 2005
Journal: Mech Dev
Title: Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development.
Volume: 122
Issue: 11
Pages: 1218-33
Publication
First Author: Ogawa T
Year: 2006
Journal: J Biol Chem
Title: Functional consequences of interactions between Pax9 and Msx1 genes in normal and abnormal tooth development.
Volume: 281
Issue: 27
Pages: 18363-9
Publication
First Author: Jonker L
Year: 2004
Journal: Mech Dev
Title: Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium.
Volume: 121
Issue: 11
Pages: 1313-22
Publication
First Author: Seki D
Year: 2015
Journal: Stem Cells Transl Med
Title: Differentiation of Odontoblast-Like Cells From Mouse Induced Pluripotent Stem Cells by Pax9 and Bmp4 Transfection.
Volume: 4
Issue: 9
Pages: 993-7
Publication
First Author: Santagati F
Year: 2001
Journal: Mamm Genome
Title: Comparative analysis of the genomic organization of Pax9 and its conserved physical association with Nkx2-9 in the human, mouse, and pufferfish genomes.
Volume: 12
Issue: 3
Pages: 232-7
GXD Expression      
Probe: MGI:6180113
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191027
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pax9
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6180113
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6191027
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pax9
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6180113
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6191027
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pax9
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6180113
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6191027
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pax9
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6180113
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191027
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pax9
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6180113
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191027
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pax9
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6180113
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6191027
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pax9
Detected: false
Specimen Num: 7
Publication
First Author: Sasaki Y
Year: 2007
Journal: Arch Oral Biol
Title: Temporal and spatial expression of Pax9 and Sonic hedgehog during development of normal mouse palates and cleft palates in TGF-beta3 null embryos.
Volume: 52
Issue: 3
Pages: 260-7
Publication
First Author: Jaskoll T
Year: 2002
Journal: Cells Tissues Organs
Title: Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice.
Volume: 170
Issue: 2-3
Pages: 83-98
GXD Expression
Probe: MGI:6256997
Assay Type: RNA in situ
Annotation Date: 2018-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3288121
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6257004
Age: embryonic day 13.5
Image: 1O
Note: Co-expression of Hey1 and Pax9 in the same cell population on the buccal side.
Specimen Label: 1O
Detected: true
Specimen Num: 1
Publication  
First Author: Stothard CA
Year: 2020
Journal: J Cardiovasc Dev Dis
Title: Pax9 and Gbx2 Interact in the Pharyngeal Endoderm to Control Cardiovascular Development.
Volume: 7
Issue: 2
Publication  
First Author: Phillips HM
Year: 2019
Journal: Development
Title: Pax9 is required for cardiovascular development and interacts with Tbx1 in the pharyngeal endoderm to control 4th pharyngeal arch artery morphogenesis.
Volume: 146
Issue: 18
Publication
First Author: Jia S
Year: 2017
Journal: Development
Title: Small-molecule Wnt agonists correct cleft palates in Pax9 mutant mice in utero.
Volume: 144
Issue: 20
Pages: 3819-3828
Publication
First Author: Sivakamasundari V
Year: 2017
Journal: Biol Open
Title: A developmental transcriptomic analysis of Pax1 and Pax9 in embryonic intervertebral disc development.
Volume: 6
Issue: 2
Pages: 187-199
Publication
First Author: Feng J
Year: 2016
Journal: Genesis
Title: Generation and characterization of tamoxifen-inducible Pax9-CreER knock-in mice using CrispR/Cas9.
Volume: 54
Issue: 9
Pages: 490-6
Publication
First Author: Khasawneh RR
Year: 2021
Journal: BMC Dev Biol
Title: Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype.
Volume: 21
Issue: 1
Pages: 14
Publication
First Author: Kist R
Year: 2007
Journal: Genesis
Title: Derivation of a mouse model for conditional inactivation of Pax9.
Volume: 45
Issue: 7
Pages: 460-4
Publication
First Author: Watanabe T
Year: 1994
Journal: Mamm Genome
Title: Fine genetic mapping defines the genetic order of Pax9, Tcf3a, and Acrodysplasia (Adp).
Volume: 5
Issue: 12
Pages: 768-70
Publication
First Author: Neubüser A
Year: 1997
Journal: Cell
Title: Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation.
Volume: 90
Issue: 2
Pages: 247-55
Publication
First Author: Ogawa T
Year: 2005
Journal: Arch Oral Biol
Title: Studies on Pax9-Msx1 protein interactions.
Volume: 50
Issue: 2
Pages: 141-5
Publication
First Author: Mansouri A
Year: 2000
Journal: Development
Title: Uncx4.1 is required for the formation of the pedicles and proximal ribs and acts upstream of Pax9.
Volume: 127
Issue: 11
Pages: 2251-8
Publication  
First Author: Madsen B
Year: 2002
Journal: Mech Dev
Title: Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer.
Volume: 119 Suppl 1
Pages: S239-46
Publication
First Author: Maguire S
Year: 2014
Journal: PLoS One
Title: Targeting of Slc25a21 is associated with orofacial defects and otitis media due to disrupted expression of a neighbouring gene.
Volume: 9
Issue: 3
Pages: e91807
Publication
First Author: Shi M
Year: 2021
Journal: J Pathol
Title: Alcohol drinking inhibits NOTCH-PAX9 signaling in esophageal squamous epithelial cells.
Volume: 253
Issue: 4
Pages: 384-395
Publication
First Author: Peters H
Year: 1999
Journal: Trends Genet
Title: Teeth. Where and how to make them.
Volume: 15
Issue: 2
Pages: 59-65
Publication
First Author: Li S
Year: 2016
Journal: Dev Biol
Title: Foxp transcription factors suppress a non-pulmonary gene expression program to permit proper lung development.
Volume: 416
Issue: 2
Pages: 338-46
Publication
First Author: Neubüser A
Year: 1995
Journal: Dev Biol
Title: Characterization and developmental expression of Pax9, a paired-box-containing gene related to Pax1.
Volume: 170
Issue: 2
Pages: 701-16
Publication
First Author: Peters H
Year: 1998
Journal: Genes Dev
Title: Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities.
Volume: 12
Issue: 17
Pages: 2735-47
Publication
First Author: ten Berge D
Year: 1998
Journal: Development
Title: Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and limbs.
Volume: 125
Issue: 19
Pages: 3831-42
Publication  
First Author: Jia S
Year: 2020
Journal: Front Physiol
Title: Pax9's Interaction With the Ectodysplasin Signaling Pathway During the Patterning of Dentition.
Volume: 11
Pages: 581843
Publication
First Author: Lu MF
Year: 1999
Journal: Development
Title: prx-1 functions cooperatively with another paired-related homeobox gene, prx-2, to maintain cell fates within the craniofacial mesenchyme.
Volume: 126
Issue: 3
Pages: 495-504
Publication
First Author: Lin D
Year: 2007
Journal: Dev Dyn
Title: Expression survey of genes critical for tooth development in the human embryonic tooth germ.
Volume: 236
Issue: 5
Pages: 1307-12
Publication  
First Author: Nagasaka A
Year: 2022
Journal: Int J Mol Sci
Title: Spatiotemporal Gene Expression Regions along the Anterior-Posterior Axis in Mouse Embryos before and after Palatal Elevation.
Volume: 23
Issue: 9
Publication
First Author: Lan Y
Year: 2004
Journal: Development
Title: Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis.
Volume: 131
Issue: 13
Pages: 3207-16
Publication
First Author: Keränen SV
Year: 1999
Journal: Dev Genes Evol
Title: Gene expression patterns associated with suppression of odontogenesis in mouse and vole diastema regions.
Volume: 209
Issue: 8
Pages: 495-506
Publication
First Author: Sonnesen L
Year: 2008
Journal: Spine (Phila Pa 1976)
Title: Association between the development of the body axis and the craniofacial skeleton studied by immunohistochemical analyses using collagen II, Pax9, Pax1, and Noggin antibodies.
Volume: 33
Issue: 15
Pages: 1622-6
Publication  
First Author: Nakatomi M
Year: 2020
Journal: Development
Title: Msx1 deficiency interacts with hypoxia and induces a morphogenetic regulation during mouse lip development.
Volume: 147
Issue: 21
Publication  
First Author: Kano S
Year: 2022
Journal: Biochem Biophys Res Commun
Title: The role of the histone methyltransferase SET domain bifurcated 1 during palatal development.
Volume: 598
Pages: 74-80
Publication
First Author: Buttitta L
Year: 2003
Journal: Development
Title: Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction.
Volume: 130
Issue: 25
Pages: 6233-43
Publication
First Author: Okubo T
Year: 2011
Journal: Development
Title: Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice.
Volume: 138
Issue: 2
Pages: 339-48
Publication
First Author: Takahashi Y
Year: 2007
Journal: Dev Dyn
Title: Transcription factors Mesp2 and Paraxis have critical roles in axial musculoskeletal formation.
Volume: 236
Issue: 6
Pages: 1484-94
Publication
First Author: Chen J
Year: 2009
Journal: Dev Biol
Title: Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development.
Volume: 334
Issue: 1
Pages: 174-85
Publication
First Author: Stafford DA
Year: 2011
Journal: Development
Title: Cooperative activity of noggin and gremlin 1 in axial skeleton development.
Volume: 138
Issue: 5
Pages: 1005-14
Publication
First Author: Ivins S
Year: 2005
Journal: Dev Biol
Title: Microarray analysis detects differentially expressed genes in the pharyngeal region of mice lacking Tbx1.
Volume: 285
Issue: 2
Pages: 554-69
Publication
First Author: Jia S
Year: 2020
Journal: Dev Dyn
Title: Pax9's dual roles in modulating Wnt signaling during murine palatogenesis.
Volume: 249
Issue: 10
Pages: 1274-1284
Publication  
First Author: Almaidhan A
Year: 2014
Journal: BMC Dev Biol
Title: Neural crest-specific deletion of Ldb1 leads to cleft secondary palate with impaired palatal shelf elevation.
Volume: 14
Pages: 3
Publication
First Author: Jing J
Year: 2022
Journal: Nat Commun
Title: Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis.
Volume: 13
Issue: 1
Pages: 4803
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory