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Search results 1 to 94 out of 94 for Paxx

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
286257 | PAXX
Type: gene
Organism: human
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Gene
505435 | PAXX
Type: gene
Organism: cattle
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Gene
492631 | paxx
Type: gene
Organism: zebrafish
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Gene
707874 | PAXX
Type: gene
Organism: macaque, rhesus
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Gene
748817 | PAXX
Type: gene
Organism: chimpanzee
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Gene
480670 | PAXX
Type: gene
Organism: dog, domestic
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Gene
100579138 | paxx
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR027873 | PAXX
Type: Family
Description: Protein PAXX is involved in DNA double-strand break (DSB) repair. PAXX interacts directly with the DSB-repair protein Ku and is recruited to DNA-damage sites in cells [].
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Gene
296565 | Paxx
Type: gene
Organism: rat
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Protein Coding Gene
MGI:2442831 | Paxx
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8K0Y7
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: false
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Protein
A2AJ30
Organism: Mus musculus/domesticus
Length: 157  
Fragment?: true
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Publication
25574025 | -
First Author: Ochi T
Year: 2015
Journal: Science
Title: DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair.
Volume: 347
Issue: 6218
Pages: 185-188
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Publication
27798842 | J:236776
First Author: Balmus G
Year: 2016
Journal: Genes Dev
Title: Synthetic lethality between PAXX and XLF in mammalian development.
Volume: 30
Issue: 19
Pages: 2152-2157
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Publication
28051062 | J:238544
 
First Author: Liu X
Year: 2017
Journal: Nat Commun
Title: PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice.
Volume: 8
Pages: 13816
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Publication
29077092 | J:274050
First Author: Abramowski V
Year: 2018
Journal: Cell Death Differ
Title: PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice.
Volume: 25
Issue: 2
Pages: 444-452
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Publication
27601633 | J:238354
First Author: Kumar V
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line.
Volume: 113
Issue: 38
Pages: 10619-24
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Publication
29511619 | J:278790
First Author: Gago-Fuentes R
Year: 2018
Journal: FEBS Open Bio
Title: Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF.
Volume: 8
Issue: 3
Pages: 426-434
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Publication
30579708 | J:286916
 
First Author: Castañeda-Zegarra S
Year: 2019
Journal: DNA Repair (Amst)
Title: Synthetic lethality between DNA repair factors Xlf and Paxx is rescued by inactivation of Trp53.
Volume: 73
Pages: 164-169
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Publication
31915249 | J:285359
First Author: Musilli S
Year: 2020
Journal: J Biol Chem
Title: An in vivo study of the impact of deficiency in the DNA repair proteins PAXX and XLF on development and maturation of the hemolymphoid system.
Volume: 295
Issue: 8
Pages: 2398-2406
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Publication
33289702 | J:305955
First Author: Castañeda-Zegarra S
Year: 2020
Journal: Aging (Albany NY)
Title: Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI.
Volume: 12
Issue: 23
Pages: 23578-23597
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Protein Coding Gene
MGP_CAROLIEiJ_G0023275 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025447 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025424 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025420 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025181 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2442831 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025864 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024644 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025159 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025292 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025254 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025378 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025285 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025923 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024392 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024713 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024733 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024192 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2017-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5827956
Age: postnatal
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2017-03-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5827956
Age: postnatal
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2017-03-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5827956
Age: postnatal
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2017-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5827956
Age: postnatal
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2017-03-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5827956
Age: postnatal
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2017-03-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5827956
Age: postnatal
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2017-03-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5827956
Age: postnatal
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2017-03-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5827956
Age: postnatal
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2017-03-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5827956
Age: postnatal
Image: 1
Specimen Label: -/-
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6885896
Age: postnatal
Specimen Label: wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2022-03-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:6885896
Age: postnatal
Specimen Label: -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2022-03-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6885896
Age: postnatal
Specimen Label: wt
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5827950
Assay Type: Western blot
Annotation Date: 2022-03-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:6885896
Age: postnatal
Specimen Label: -/-
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:4416990
Assay Type: RNA in situ
Annotation Date: 2023-09-26
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7530868
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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Publication
34519267 | J:316933
   
First Author: Roch B
Year: 2021
Journal: Elife
Title: An XRCC4 mutant mouse, a model for human X4 syndrome, reveals interplays with Xlf, PAXX, and ATM in lymphoid development.
Volume: 10
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UniProt Feature
UniProt Feature
Begin: 1
Description: Protein PAXX
Type: chain
End: 205
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Publication
12477932 | J:82808
First Author: Strausberg RL
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Volume: 99
Issue: 26
Pages: 16899-903
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
29511621 | -
First Author: Dewan A
Year: 2018
Journal: FEBS Open Bio
Title: Robust DNA repair in PAXX-deficient mammalian cells.
Volume: 8
Issue: 3
Pages: 442-448
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Publication
27601299 | -
First Author: Lescale C
Year: 2016
Journal: Cell Rep
Title: Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination.
Volume: 16
Issue: 11
Pages: 2967-2979
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Publication
27830975 | -
First Author: Hung PJ
Year: 2017
Journal: Cell Cycle
Title: Deficiency of XLF and PAXX prevents DNA double-strand break repair by non-homologous end joining in lymphocytes.
Volume: 16
Issue: 3
Pages: 286-295
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Allele
Paxx<tm1.1Shzh> | MGI:5888857
Name: non-homologous end joining factor; targeted mutation 1.1, Shan Zha
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
31795137 | J:306598
 
First Author: Castañeda-Zegarra S
Year: 2019
Journal: Biomolecules
Title: Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren.
Volume: 9
Issue: 12
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Publication
28759779 | J:277029
 
First Author: Xing M
Year: 2017
Journal: DNA Repair (Amst)
Title: Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70.
Volume: 57
Pages: 133-138
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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