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Search results 1 to 84 out of 84 for Pcdha1

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
56147 | PCDHA1
Type: gene
Organism: human
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Gene
393085 | Pcdha1
Type: gene
Organism: rat
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Gene
487164 | PCDHA1
Type: gene
Organism: dog, domestic
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Gene
737736 | PCDHA1
Type: gene
Organism: chimpanzee
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Gene
497211 | PCDHA1
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:2150982 | Pcdha1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR030740 | PCDHA1
Type: Family
Description: The clustered protocadherin (Pcdh) family is the largest subgroup of the cadherin superfamily. In mammals, the clustered Pcdh family consists of three gene clusters: Pcdh-alpha, Pcdh-beta, and Pcdh-gamma (Pcdhg) []. The genomic organisation of the human protocadherin gene clusters is remarkably similar to that of immunoglobulin and T-cell receptor genes. The extracellular and transmembrane domains of each protocadherin protein are encoded by an unusually large "variable"region exon, while the intracellular domains are encoded by three small "constant"region exons located downstream from a tandem array of variable region exons [, ]. The clustered Pcdh proteins are predominantly expressed in the brain []. Pcdh cluster genes may contribute to specifying the identity and diversity of individual neurons [].Pcdhs-alpha are involved in axonal coalescence of olfactory sensory neurons []and visual acuity in mice []. The Pcdh-alpha gene cluster contains 14 members in mouse. This entry represents protocadherin alpha-1.
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GXD Expression
GXD Expression
   
Probe: MGI:7712142
Assay Type: RT-PCR
Annotation Date: 2024-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7712852
Age: postnatal day 30
Image: 1
Specimen Label: Pcdha1
Detected: true
Specimen Num: 1
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Publication
11230163 | J:67989
First Author: Wu Q
Year: 2001
Journal: Genome Res
Title: Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.
Volume: 11
Issue: 3
Pages: 389-404
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Protein
Q91Y12
Organism: Mus musculus/domesticus
Length: 946  
Fragment?: false
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Publication
10380929 | J:86878
First Author: Wu Q
Year: 1999
Journal: Cell
Title: A striking organization of a large family of human neural cadherin-like cell adhesion genes.
Volume: 97
Issue: 6
Pages: 779-90
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Protein
Q91Y21
Organism: Mus musculus/domesticus
Length: 948  
Fragment?: false
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Protein
Q641K6
Organism: Mus musculus/domesticus
Length: 902  
Fragment?: false
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Publication
18430161 | -
 
First Author: Yagi T
Year: 2008
Journal: Dev Growth Differ
Title: Clustered protocadherin family.
Volume: 50 Suppl 1
Pages: S131-40
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Publication
22969705 | J:312046
 
First Author: Hirano K
Year: 2012
Journal: Front Mol Neurosci
Title: Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems.
Volume: 5
Pages: 90
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Publication
18353676 | J:136920
First Author: Hasegawa S
Year: 2008
Journal: Mol Cell Neurosci
Title: The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse.
Volume: 38
Issue: 1
Pages: 66-79
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Publication
25650227 | J:221160
First Author: Meguro R
Year: 2015
Journal: J Neurochem
Title: Impaired clustered protocadherin-α leads to aggregated retinogeniculate terminals and impaired visual acuity in mice.
Volume: 133
Issue: 1
Pages: 66-72
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Protein Coding Gene
MGP_CAROLIEiJ_G0022141 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024294 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024260 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024228 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024260 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024027 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2150982 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024701 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023502 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023995 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024127 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024094 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024209 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024122 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024750 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023246 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023565 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018875 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023054 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:2680981
Assay Type: Northern blot
Annotation Date: 2003-12-10
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:2680983
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2680981
Assay Type: Northern blot
Annotation Date: 2003-12-10
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2680983
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2680981
Assay Type: Northern blot
Annotation Date: 2003-12-10
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2680983
Age: postnatal day 10
Specimen Label: P10
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2680981
Assay Type: Northern blot
Annotation Date: 2003-12-10
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2680983
Age: postnatal day 30
Specimen Label: P30
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2680981
Assay Type: Northern blot
Annotation Date: 2003-12-10
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2680983
Age: postnatal day 56
Specimen Label: P56
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2682216
Assay Type: RT-PCR
Annotation Date: 2003-12-26
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:2682221
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2682216
Assay Type: RT-PCR
Annotation Date: 2003-12-26
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2682221
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2682216
Assay Type: RT-PCR
Annotation Date: 2003-12-26
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2682221
Age: postnatal day 10
Specimen Label: P10
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2682216
Assay Type: RT-PCR
Annotation Date: 2003-12-26
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2682221
Age: postnatal day 30
Specimen Label: P30
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2682216
Assay Type: RT-PCR
Annotation Date: 2003-12-26
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2682221
Age: postnatal day 56
Specimen Label: P56
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2682216
Assay Type: RT-PCR
Annotation Date: 2003-12-26
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:2682228
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2682216
Assay Type: RT-PCR
Annotation Date: 2003-12-26
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:2682228
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2682216
Assay Type: RT-PCR
Annotation Date: 2003-12-26
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2682228
Age: postnatal day 10
Specimen Label: P10
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2682216
Assay Type: RT-PCR
Annotation Date: 2003-12-26
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2682228
Age: postnatal day 30
Specimen Label: P30
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2682216
Assay Type: RT-PCR
Annotation Date: 2003-12-26
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2682228
Age: postnatal day 56
Specimen Label: P56
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:7489694
Assay Type: RT-PCR
Annotation Date: 2023-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7489717
Age: embryonic day 13.5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7489694
Assay Type: RT-PCR
Annotation Date: 2023-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7489717
Age: embryonic day 13.5
Specimen Label: Dnmt3b-KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7711013
Assay Type: RT-PCR
Annotation Date: 2024-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:7711188
Age: embryonic day 14.0
Image: 1
Specimen Label: control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7711013
Assay Type: RT-PCR
Annotation Date: 2024-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:7711188
Age: embryonic day 14.0
Image: 1
Specimen Label: CtcfNesCre
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:3232878
Assay Type: RNA in situ
Annotation Date: 2008-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:3817580
Age: embryonic day 15.5
Image: 1
Note: Expression is present in the enteric nervous system.
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3232878
Assay Type: RNA in situ
Annotation Date: 2008-11-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2692223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3817580
Age: embryonic day 15.5
Image: 1
Specimen Label: 1
Detected: true
Specimen Num: 1
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Publication
11401448 | J:68765
First Author: Takei Y
Year: 2001
Journal: Genomics
Title: Two novel CNRs from the CNR gene cluster have molecular features distinct from those of CNR1 to 8.
Volume: 72
Issue: 3
Pages: 321-30
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Publication
21917590 | J:183013
First Author: O'Leary R
Year: 2011
Journal: Mol Biol Cell
Title: A variable cytoplasmic domain segment is necessary for γ-protocadherin trafficking and tubulation in the endosome/lysosome pathway.
Volume: 22
Issue: 22
Pages: 4362-72
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Publication
15640798 | J:96434
First Author: Esumi S
Year: 2005
Journal: Nat Genet
Title: Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.
Volume: 37
Issue: 2
Pages: 171-6
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Publication
15570159 | J:103707
First Author: Morishita H
Year: 2004
Journal: Neuroreport
Title: CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.
Volume: 15
Issue: 17
Pages: 2595-9
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Publication
17572674 | J:123007
First Author: Wu S
Year: 2007
Journal: Nat Genet
Title: Toward simpler and faster genome-wide mutagenesis in mice.
Volume: 39
Issue: 7
Pages: 922-30
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Publication
24698270 | J:259654
First Author: Toyoda S
Year: 2014
Journal: Neuron
Title: Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.
Volume: 82
Issue: 1
Pages: 94-108
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Publication
29911975 | J:264145
   
First Author: Fan L
Year: 2018
Journal: Elife
Title: Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.
Volume: 7
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Publication
15347688 | J:94992
First Author: Murata Y
Year: 2004
Journal: J Biol Chem
Title: Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.
Volume: 279
Issue: 47
Pages: 49508-16
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Publication
32633719 | J:293992
   
First Author: Mancia Leon WR
Year: 2020
Journal: Elife
Title: Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.
Volume: 9
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Publication
23754746 | J:204566
First Author: Gendrel AV
Year: 2013
Journal: Mol Cell Biol
Title: Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes.
Volume: 33
Issue: 16
Pages: 3150-65
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Publication
30377227 | J:269929
First Author: Elbert A
Year: 2019
Journal: J Neurosci
Title: CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.
Volume: 39
Issue: 1
Pages: 177-192
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Publication
16632597 | J:109593
First Author: Heanue TA
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Expression profiling the developing mammalian enteric nervous system identifies marker and candidate Hirschsprung disease genes.
Volume: 103
Issue: 18
Pages: 6919-24
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Del(18Pcdha1-Pcdhb22)8Tyag | MGI:7530993
Name: deletion, Chr 18, Takeshi Yagi 8
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:6353892 | B6;CBA-Del(18Pcdha1-Pcdhb22)8Tyag/TyagRbrc
Attribute String: targeted mutation, mutant stock
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Publication
28066179 | J:244163
 
First Author: Hasegawa S
Year: 2016
Journal: Front Mol Neurosci
Title: Distinct and Cooperative Functions for the Protocadherin-α, -β and -γ Clusters in Neuronal Survival and Axon Targeting.
Volume: 9
Pages: 155
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom