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Search results 1 to 49 out of 49 for Pcdhac1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: Pcdhs-alpha are involved in axonal coalescence of olfactory sensory neurons []and visual acuity in mice []. The Pcdh-alpha gene cluster contains 14 members in mouse. This entry represents protocadherin alpha-C1.The clustered protocadherin (Pcdh) family is the largest subgroup of the cadherin superfamily. In mammals, the clustered Pcdh family consists of three gene clusters: Pcdh-alpha, Pcdh-beta, and Pcdh-gamma (Pcdhg) []. The genomic organisation of the human protocadherin gene clusters is remarkably similar to that of immunoglobulin and T-cell receptor genes. The extracellular and transmembrane domains of each protocadherin protein are encoded by an unusually large "variable"region exon, while the intracellular domains are encoded by three small "constant"region exons located downstream from a tandem array of variable region exons [, ]. The clustered Pcdh proteins are predominantly expressed in the brain []. Pcdh cluster genes may contribute to specifying the identity and diversity of individual neurons [].
Publication
First Author: Wu Q
Year: 2001
Journal: Genome Res
Title: Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.
Volume: 11
Issue: 3
Pages: 389-404
Publication
First Author: Wu Q
Year: 1999
Journal: Cell
Title: A striking organization of a large family of human neural cadherin-like cell adhesion genes.
Volume: 97
Issue: 6
Pages: 779-90
Protein
Organism: Mus musculus
Length: 964  
Fragment?: false
Publication  
First Author: Yagi T
Year: 2008
Journal: Dev Growth Differ
Title: Clustered protocadherin family.
Volume: 50 Suppl 1
Pages: S131-40
Publication  
First Author: Hirano K
Year: 2012
Journal: Front Mol Neurosci
Title: Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems.
Volume: 5
Pages: 90
Publication
First Author: Hasegawa S
Year: 2008
Journal: Mol Cell Neurosci
Title: The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse.
Volume: 38
Issue: 1
Pages: 66-79
Publication
First Author: Meguro R
Year: 2015
Journal: J Neurochem
Title: Impaired clustered protocadherin-α leads to aggregated retinogeniculate terminals and impaired visual acuity in mice.
Volume: 133
Issue: 1
Pages: 66-72
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Esumi S
Year: 2005
Journal: Nat Genet
Title: Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.
Volume: 37
Issue: 2
Pages: 171-6
Publication    
First Author: Fan L
Year: 2018
Journal: Elife
Title: Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.
Volume: 7
Publication
First Author: Morishita H
Year: 2004
Journal: Neuroreport
Title: CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.
Volume: 15
Issue: 17
Pages: 2595-9
Publication
First Author: Wu S
Year: 2007
Journal: Nat Genet
Title: Toward simpler and faster genome-wide mutagenesis in mice.
Volume: 39
Issue: 7
Pages: 922-30
Publication
First Author: Toyoda S
Year: 2014
Journal: Neuron
Title: Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.
Volume: 82
Issue: 1
Pages: 94-108
Publication    
First Author: Mancia Leon WR
Year: 2020
Journal: Elife
Title: Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.
Volume: 9
Publication
First Author: Elbert A
Year: 2019
Journal: J Neurosci
Title: CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.
Volume: 39
Issue: 1
Pages: 177-192
Publication      
First Author: Lo C
Year: 2011
Journal: MGI Direct Data Submission (B2B/CvDC)
Title: Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC)
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication
First Author: Noguchi Y
Year: 2009
Journal: J Biol Chem
Title: Total expression and dual gene-regulatory mechanisms maintained in deletions and duplications of the Pcdha cluster.
Volume: 284
Issue: 46
Pages: 32002-14