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Search results 1 to 68 out of 68 for Pcdhga1

0.026s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: The 22 isoforms of the Pcdhg gene cluster are diversified into A-, B-, and C-types []. This entry represents protocadherin gamma-A1.The clustered protocadherin (Pcdh) family is the largest subgroup of the cadherin superfamily. In mammals, the clustered Pcdh family consists of three gene clusters: Pcdh-alpha, Pcdh-beta, and Pcdh-gamma (Pcdhg) []. The genomic organisation of the human protocadherin gene clusters is remarkably similar to that of immunoglobulin and T-cell receptor genes. The extracellular and transmembrane domains of each protocadherin protein are encoded byan unusually large "variable"region exon, while the intracellular domains are encoded by three small "constant"region exons located downstream from a tandem array of variable region exons [, ]. The clustered Pcdh proteins are predominantly expressed in the brain []. Pcdh cluster genes may contribute to specifying the identity and diversity of individual neurons [].
Publication
First Author: Wu Q
Year: 2001
Journal: Genome Res
Title: Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.
Volume: 11
Issue: 3
Pages: 389-404
Publication
First Author: Chen WV
Year: 2012
Journal: Neuron
Title: Functional significance of isoform diversification in the protocadherin gamma gene cluster.
Volume: 75
Issue: 3
Pages: 402-9
Publication
First Author: Wu Q
Year: 1999
Journal: Cell
Title: A striking organization of a large family of human neural cadherin-like cell adhesion genes.
Volume: 97
Issue: 6
Pages: 779-90
Protein
Organism: Mus musculus
Length: 810  
Fragment?: false
Protein
Organism: Mus musculus
Length: 931  
Fragment?: false
Publication  
First Author: Yagi T
Year: 2008
Journal: Dev Growth Differ
Title: Clustered protocadherin family.
Volume: 50 Suppl 1
Pages: S131-40
Publication  
First Author: Hirano K
Year: 2012
Journal: Front Mol Neurosci
Title: Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems.
Volume: 5
Pages: 90
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Frank M
Year: 2005
Journal: Mol Cell Neurosci
Title: Differential expression of individual gamma-protocadherins during mouse brain development.
Volume: 29
Issue: 4
Pages: 603-16
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication  
First Author: Ledderose J
Year: 2013
Journal: Sci Rep
Title: Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression.
Volume: 3
Pages: 1514
Publication
First Author: Prasad T
Year: 2008
Journal: Development
Title: A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene cluster.
Volume: 135
Issue: 24
Pages: 4153-64
Publication    
First Author: Mancia Leon WR
Year: 2020
Journal: Elife
Title: Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.
Volume: 9
Publication
First Author: Wu S
Year: 2007
Journal: Nat Genet
Title: Toward simpler and faster genome-wide mutagenesis in mice.
Volume: 39
Issue: 7
Pages: 922-30
Publication
First Author: Murata Y
Year: 2004
Journal: J Biol Chem
Title: Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.
Volume: 279
Issue: 47
Pages: 49508-16
Publication
First Author: Bonn S
Year: 2007
Journal: Mol Cell Biol
Title: Combinatorial expression of alpha- and gamma-protocadherins alters their presenilin-dependent processing.
Volume: 27
Issue: 11
Pages: 4121-32
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
GXD Expression      
Probe: MGI:5779327
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:5779369
Age: embryonic day 17.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5779327
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5779369
Age: postnatal day 0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5779327
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5779369
Age: postnatal day 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5779327
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779369
Age: postnatal day 6
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5779327
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779369
Age: postnatal day 9
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5779327
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779369
Age: postnatal day 14
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5779327
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779369
Age: postnatal day 21
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5779327
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779369
Age: postnatal day 29
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5779327
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779369
Age: postnatal adult
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5779327
Assay Type: RNA in situ
Annotation Date: 2016-06-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3521928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779343
Age: postnatal day 9
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5779317
Assay Type: Immunohistochemistry
Annotation Date: 2016-06-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3525728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779404
Age: postnatal day 21
Note: Strong expression in the cell bodies and intense punctate staining in the neuropil.
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5779317
Assay Type: Immunohistochemistry
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779404
Age: postnatal day 21
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5779317
Assay Type: Immunohistochemistry
Annotation Date: 2016-06-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779404
Age: postnatal day 21
Note: Strong expression in the cell bodies and intense punctate staining in the neuropil.
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5779327
Assay Type: RNA in situ
Annotation Date: 2016-06-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3522128
Stage: TS28
Assay Id: MGI:5779343
Age: postnatal day 9
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5779327
Assay Type: RNA in situ
Annotation Date: 2016-06-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3523528
Stage: TS28
Assay Id: MGI:5779343
Age: postnatal day 9
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5779317
Assay Type: Immunohistochemistry
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779404
Age: postnatal day 21
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5779327
Assay Type: RNA in situ
Annotation Date: 2016-06-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779343
Age: postnatal day 9
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5779327
Assay Type: RNA in situ
Annotation Date: 2016-06-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3521628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779343
Age: postnatal day 9
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5779317
Assay Type: Immunohistochemistry
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779404
Age: postnatal day 21
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5779327
Assay Type: RNA in situ
Annotation Date: 2016-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:5779343
Age: postnatal
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5779327
Assay Type: RNA in situ
Annotation Date: 2016-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:5779343
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5779327
Assay Type: RNA in situ
Annotation Date: 2016-06-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5779343
Age: embryonic day 17.0
Detected: true
Specimen Num: 4
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database