Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The clustered protocadherin (Pcdh) family is the largest subgroup of the cadherin superfamily. In mammals, the clustered Pcdh family consists of three gene clusters: Pcdh-alpha, Pcdh-beta, and Pcdh-gamma (Pcdhg) []. The genomic organisation of the human protocadherin gene clusters is remarkably similar to that of immunoglobulin and T-cell receptor genes. The extracellular and transmembrane domains of each protocadherin protein are encoded by an unusually large "variable"region exon, while the intracellular domains are encoded by three small "constant"region exons located downstream from a tandem array of variable region exons [, ]. The clustered Pcdh proteins are predominantly expressed in the brain []. Pcdh cluster genes may contribute to specifying the identity and diversity of individual neurons [].The 22 isoforms of the Pcdhg gene cluster are diversified into A-, B-, and C-types []. This entry represents protocadherin gamma-A1. |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7712172 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-08-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7712897 |
Age: |
postnatal day 30 |
Image: |
1 |
|
Specimen Label: |
Pcdhga1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu Q |
Year: |
2001 |
Journal: |
Genome Res |
Title: |
Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. |
Volume: |
11 |
Issue: |
3 |
Pages: |
389-404 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen WV |
Year: |
2012 |
Journal: |
Neuron |
Title: |
Functional significance of isoform diversification in the protocadherin gamma gene cluster. |
Volume: |
75 |
Issue: |
3 |
Pages: |
402-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu Q |
Year: |
1999 |
Journal: |
Cell |
Title: |
A striking organization of a large family of human neural cadherin-like cell adhesion genes. |
Volume: |
97 |
Issue: |
6 |
Pages: |
779-90 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
931
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
810
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Yagi T |
Year: |
2008 |
Journal: |
Dev Growth Differ |
Title: |
Clustered protocadherin family. |
Volume: |
50 Suppl 1 |
|
Pages: |
S131-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hirano K |
Year: |
2012 |
Journal: |
Front Mol Neurosci |
Title: |
Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems. |
Volume: |
5 |
|
Pages: |
90 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
Northern blot |
Annotation Date: |
2016-06-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689425 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5779369 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
E17 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
Northern blot |
Annotation Date: |
2016-06-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689427 |
|
Stage: |
TS27 |
Assay Id: |
MGI:5779369 |
Age: |
postnatal day 0 |
|
|
Specimen Label: |
P0 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
Northern blot |
Annotation Date: |
2016-06-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689427 |
|
Stage: |
TS27 |
Assay Id: |
MGI:5779369 |
Age: |
postnatal day 3 |
|
|
Specimen Label: |
P3 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
Northern blot |
Annotation Date: |
2016-06-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5779369 |
Age: |
postnatal day 6 |
|
|
Specimen Label: |
P6 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
Northern blot |
Annotation Date: |
2016-06-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5779369 |
Age: |
postnatal day 9 |
|
|
Specimen Label: |
P9 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
Northern blot |
Annotation Date: |
2016-06-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5779369 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
P14 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
Northern blot |
Annotation Date: |
2016-06-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5779369 |
Age: |
postnatal day 21 |
|
|
Specimen Label: |
P21 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
Northern blot |
Annotation Date: |
2016-06-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5779369 |
Age: |
postnatal day 29 |
|
|
Specimen Label: |
P29 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
Northern blot |
Annotation Date: |
2016-06-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5779369 |
Age: |
postnatal adult |
|
|
Specimen Label: |
ad |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
RNA in situ |
Annotation Date: |
2016-06-27 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3521928 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5779343 |
Age: |
postnatal day 9 |
|
|
Specimen Label: |
5B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779317 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-06-28 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3525728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5779404 |
Age: |
postnatal day 21 |
|
Note: |
Strong expression in the cell bodies and intense punctate staining in the neuropil. |
Specimen Label: |
8D/D'/D" |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779317 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-06-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5779404 |
Age: |
postnatal day 21 |
|
|
Specimen Label: |
8D/D'/D" |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779317 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-06-28 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5779404 |
Age: |
postnatal day 21 |
|
Note: |
Strong expression in the cell bodies and intense punctate staining in the neuropil. |
Specimen Label: |
8D/D'/D" |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
RNA in situ |
Annotation Date: |
2016-06-27 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3522128 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5779343 |
Age: |
postnatal day 9 |
|
|
Specimen Label: |
5B |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
RNA in situ |
Annotation Date: |
2016-06-27 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3523528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5779343 |
Age: |
postnatal day 9 |
|
|
Specimen Label: |
5B |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779317 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-06-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3284528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5779404 |
Age: |
postnatal day 21 |
|
|
Specimen Label: |
8D/D'/D" |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
RNA in situ |
Annotation Date: |
2016-06-27 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3522328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5779343 |
Age: |
postnatal day 9 |
|
|
Specimen Label: |
5B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
RNA in situ |
Annotation Date: |
2016-06-27 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3521628 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5779343 |
Age: |
postnatal day 9 |
|
|
Specimen Label: |
5B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779317 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-06-28 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3280928 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5779404 |
Age: |
postnatal day 21 |
|
|
Specimen Label: |
8D/D'/D" |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
RNA in situ |
Annotation Date: |
2016-06-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
Pattern: |
Widespread |
Stage: |
TS28 |
Assay Id: |
MGI:5779343 |
Age: |
postnatal |
|
|
Specimen Label: |
not shown |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
RNA in situ |
Annotation Date: |
2016-06-27 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
Pattern: |
Widespread |
Stage: |
TS28 |
Assay Id: |
MGI:5779343 |
Age: |
postnatal adult |
|
|
Specimen Label: |
not shown |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5779327 |
Assay Type: |
RNA in situ |
Annotation Date: |
2016-06-27 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689425 |
Pattern: |
Not Specified |
Stage: |
TS25 |
Assay Id: |
MGI:5779343 |
Age: |
embryonic day 17.0 |
|
|
Specimen Label: |
not shown |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bonn S |
Year: |
2007 |
Journal: |
Mol Cell Biol |
Title: |
Combinatorial expression of alpha- and gamma-protocadherins alters their presenilin-dependent processing. |
Volume: |
27 |
Issue: |
11 |
Pages: |
4121-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Frank M |
Year: |
2005 |
Journal: |
Mol Cell Neurosci |
Title: |
Differential expression of individual gamma-protocadherins during mouse brain development. |
Volume: |
29 |
Issue: |
4 |
Pages: |
603-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ledderose J |
Year: |
2013 |
Journal: |
Sci Rep |
Title: |
Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression. |
Volume: |
3 |
|
Pages: |
1514 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu S |
Year: |
2007 |
Journal: |
Nat Genet |
Title: |
Toward simpler and faster genome-wide mutagenesis in mice. |
Volume: |
39 |
Issue: |
7 |
Pages: |
922-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Murata Y |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha. |
Volume: |
279 |
Issue: |
47 |
Pages: |
49508-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mancia Leon WR |
Year: |
2020 |
Journal: |
Elife |
Title: |
Clustered gamma-protocadherins regulate cortical interneuron programmed cell death. |
Volume: |
9 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Prasad T |
Year: |
2008 |
Journal: |
Development |
Title: |
A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene cluster. |
Volume: |
135 |
Issue: |
24 |
Pages: |
4153-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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