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Search results 1 to 97 out of 97 for Pcdhgc3

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
5098 | PCDHGC3
Type: gene
Organism: human
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Gene
114678923 | PCDHGC3
Type: gene
Organism: macaque, rhesus
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Gene
116782 | Pcdhgc3
Type: gene
Organism: rat
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Gene
100034695 | PCDHGC3
Type: gene
Organism: chimpanzee
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Gene
100125301 | PCDHGC3
Type: gene
Organism: cattle
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Gene
408051 | PCDHGC3
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:1935201 | Pcdhgc3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR030728 | PCDHGC3
Type: Family
Description: The clustered protocadherin (Pcdh) family is the largest subgroup of the cadherin superfamily. In mammals, the clustered Pcdh family consists of three gene clusters: Pcdh-alpha, Pcdh-beta, and Pcdh-gamma (Pcdhg) []. The genomic organisation of the human protocadherin gene clusters is remarkably similar to that of immunoglobulin and T-cell receptor genes. The extracellular and transmembrane domains of each protocadherin protein are encoded by an unusually large "variable"region exon, while the intracellular domains are encoded by three small "constant"region exons located downstream from a tandem array of variable region exons [, ]. The clustered Pcdh proteins are predominantly expressed in the brain []. Pcdh cluster genes may contribute to specifying the identity and diversity of individual neurons [].The 22 isoforms of the Pcdhg gene cluster are diversified into A-, B-, and C-types, and the C-type isoforms differ from all other clustered Pcdhs in sequence and expression. Mice lacking the three C-type isoforms (Pcdhgc3, Pcdhgc4, Pcdhgc5) display cellular and synaptic alterations resulting from neuronal apoptosis [].This entry represents protocadherin gamma-C3.
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GXD Expression
GXD Expression
   
Probe: MGI:7712166
Assay Type: RT-PCR
Annotation Date: 2024-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7712928
Age: postnatal day 30
Image: 1
Specimen Label: Pcdhgc3
Detected: true
Specimen Num: 1
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Publication
11230163 | J:67989
First Author: Wu Q
Year: 2001
Journal: Genome Res
Title: Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.
Volume: 11
Issue: 3
Pages: 389-404
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Publication
22884324 | J:188341
First Author: Chen WV
Year: 2012
Journal: Neuron
Title: Functional significance of isoform diversification in the protocadherin gamma gene cluster.
Volume: 75
Issue: 3
Pages: 402-9
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Protein
Q4KMN6
Organism: Mus musculus/domesticus
Length: 570  
Fragment?: false
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Publication
10380929 | J:86878
First Author: Wu Q
Year: 1999
Journal: Cell
Title: A striking organization of a large family of human neural cadherin-like cell adhesion genes.
Volume: 97
Issue: 6
Pages: 779-90
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Protein
A0A0A6YWM6
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: false
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Protein
Q91XX1
Organism: Mus musculus/domesticus
Length: 934  
Fragment?: false
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Publication
18430161 | -
 
First Author: Yagi T
Year: 2008
Journal: Dev Growth Differ
Title: Clustered protocadherin family.
Volume: 50 Suppl 1
Pages: S131-40
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Publication
22969705 | J:312046
 
First Author: Hirano K
Year: 2012
Journal: Front Mol Neurosci
Title: Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems.
Volume: 5
Pages: 90
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Protein Coding Gene
MGP_CAROLIEiJ_G0022199 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0024351 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024318 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024287 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024318 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0024084 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1935201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023559 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0024054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024184 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0024150 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024268 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024181 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024809 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023303 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023622 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018932 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0023108 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8719883 | J:30668
 
First Author: Obata S
Year: 1995
Journal: J Cell Sci
Title: Protocadherin Pcdh2 shows properties similar to, but distinct from, those of classical cadherins.
Volume: 108 ( Pt 12)
Pages: 3765-73
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GXD Expression
GXD Expression
     
Probe: MGI:5779331
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:5779373
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5779331
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5779373
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5779331
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5779373
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5779331
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779373
Age: postnatal day 6
Specimen Label: P6
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5779331
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779373
Age: postnatal day 9
Specimen Label: P9
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5779331
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779373
Age: postnatal day 14
Specimen Label: P14
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:5779331
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779373
Age: postnatal day 21
Specimen Label: P21
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:5779331
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779373
Age: postnatal day 29
Specimen Label: P29
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:5779331
Assay Type: Northern blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779373
Age: postnatal adult
Specimen Label: ad
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:5779322
Assay Type: Western blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:5779376
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:5779322
Assay Type: Western blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5779376
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5779322
Assay Type: Western blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779376
Age: postnatal day 6
Specimen Label: P6
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5779322
Assay Type: Western blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779376
Age: postnatal day 15
Specimen Label: P15
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:5779322
Assay Type: Western blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779376
Age: postnatal day 24
Specimen Label: P24
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:5779322
Assay Type: Western blot
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5779376
Age: postnatal adult
Specimen Label: ad
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:7489715
Assay Type: RT-PCR
Annotation Date: 2023-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7489738
Age: embryonic day 13.5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7489715
Assay Type: RT-PCR
Annotation Date: 2023-06-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:7489738
Age: embryonic day 13.5
Specimen Label: Dnmt3b-KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7711061
Assay Type: RT-PCR
Annotation Date: 2024-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:7711323
Age: embryonic day 14.0
Image: 1
Specimen Label: control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7711061
Assay Type: RT-PCR
Annotation Date: 2024-08-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691022
Stage: TS22
Assay Id: MGI:7711323
Age: embryonic day 14.0
Image: 1
Specimen Label: CtcfNesCre
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5779324
Assay Type: Immunohistochemistry
Annotation Date: 2016-06-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3525728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779378
Age: postnatal day 21
Note: Some major dendritic branches of the cortical neurons were diffusely outlined.
Specimen Label: 8B/B'/B"
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4428785
Assay Type: RNA in situ
Annotation Date: 2023-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7522944
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5779324
Assay Type: Immunohistochemistry
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779378
Age: postnatal day 21
Specimen Label: 8B/B'/B"
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5779324
Assay Type: Immunohistochemistry
Annotation Date: 2016-06-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779378
Age: postnatal day 21
Note: Some major dendritic branches of the cortical neurons were diffusely outlined.
Specimen Label: 8B/B'/B"
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5779324
Assay Type: Immunohistochemistry
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779378
Age: postnatal day 21
Specimen Label: 8B/B'/B"
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5779331
Assay Type: RNA in situ
Annotation Date: 2016-06-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779345
Age: postnatal day 9
Note: Very prominent.
Specimen Label: 5D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5779331
Assay Type: RNA in situ
Annotation Date: 2016-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521628
Pattern: Single cells
Stage: TS28
Assay Id: MGI:5779345
Age: postnatal day 9
Note: Present in a subset of cells.
Specimen Label: 5D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4428785
Assay Type: RNA in situ
Annotation Date: 2023-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7522944
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5779324
Assay Type: Immunohistochemistry
Annotation Date: 2016-06-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5779378
Age: postnatal day 21
Specimen Label: 8B/B'/B"
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5779331
Assay Type: RNA in situ
Annotation Date: 2016-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:5779345
Age: postnatal
Specimen Label: not shown
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5779331
Assay Type: RNA in situ
Annotation Date: 2016-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Widespread
Stage: TS28
Assay Id: MGI:5779345
Age: postnatal adult
Specimen Label: not shown
Detected: true
Specimen Num: 3
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Publication
22542181 | J:188387
First Author: Garrett AM
Year: 2012
Journal: Neuron
Title: γ-protocadherins control cortical dendrite arborization by regulating the activity of a FAK/PKC/MARCKS signaling pathway.
Volume: 74
Issue: 2
Pages: 269-76
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Publication
36604170 | J:338247
First Author: Steffen DM
Year: 2023
Journal: J Neurosci
Title: A Unique Role for Protocadherin γC3 in Promoting Dendrite Arborization through an Axin1-Dependent Mechanism.
Volume: 43
Issue: 6
Pages: 918-935
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Publication
16751190 | J:116465
First Author: Reiss K
Year: 2006
Journal: J Biol Chem
Title: Regulated ADAM10-dependent ectodomain shedding of gamma-protocadherin C3 modulates cell-cell adhesion.
Volume: 281
Issue: 31
Pages: 21735-44
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Publication
8575755 | J:29362
First Author: Sago H
Year: 1995
Journal: Genomics
Title: Cloning, expression, and chromosomal localization of a novel cadherin-related protein, protocadherin-3.
Volume: 29
Issue: 3
Pages: 631-40
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Publication
15964765 | J:100649
First Author: Frank M
Year: 2005
Journal: Mol Cell Neurosci
Title: Differential expression of individual gamma-protocadherins during mouse brain development.
Volume: 29
Issue: 4
Pages: 603-16
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Publication
23515096 | J:195283
 
First Author: Ledderose J
Year: 2013
Journal: Sci Rep
Title: Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression.
Volume: 3
Pages: 1514
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Publication
24698270 | J:259654
First Author: Toyoda S
Year: 2014
Journal: Neuron
Title: Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.
Volume: 82
Issue: 1
Pages: 94-108
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Publication
15347688 | J:94992
First Author: Murata Y
Year: 2004
Journal: J Biol Chem
Title: Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.
Volume: 279
Issue: 47
Pages: 49508-16
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Publication
32633719 | J:293992
   
First Author: Mancia Leon WR
Year: 2020
Journal: Elife
Title: Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.
Volume: 9
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Publication
19029045 | J:142349
First Author: Prasad T
Year: 2008
Journal: Development
Title: A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene cluster.
Volume: 135
Issue: 24
Pages: 4153-64
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Publication
30377227 | J:269929
First Author: Elbert A
Year: 2019
Journal: J Neurosci
Title: CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.
Volume: 39
Issue: 1
Pages: 177-192
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
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Pages: 130-136
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First Author: MGD Nomenclature Committee
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Title: Nomenclature Committee Use
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12466851 | J:80000
First Author: Okazaki Y
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Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
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First Author: Diez-Roux G
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Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
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First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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First Author: Allen Institute for Brain Science
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Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
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Journal: Database Download
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First Author: Mouse Genome Informatics Group
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Journal: Database Procedure
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Journal: Database Release
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Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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First Author: Mouse Genome Informatics Scientific Curators
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Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Journal: Neuron
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Pages: 1776-1794.e10
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Journal: Genome Res
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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