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Search results 1 to 100 out of 205 for Pcf11

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein
Organism: Mus musculus
Length: 1254  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1254  
Fragment?: true
Gene
Type: gene
Organism: Homo sapiens
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Protein
Organism: Mus musculus
Length: 78  
Fragment?: false
Protein
Organism: Mus musculus
Length: 300  
Fragment?: true
Protein
Organism: Mus musculus
Length: 546  
Fragment?: true
Protein
Organism: Mus musculus
Length: 814  
Fragment?: true
Protein
Organism: Mus musculus
Length: 508  
Fragment?: true
Publication
First Author: Ghazy MA
Year: 2012
Journal: Nucleic Acids Res
Title: The interaction of Pcf11 and Clp1 is needed for mRNA 3'-end formation and is modulated by amino acids in the ATP-binding site.
Volume: 40
Issue: 3
Pages: 1214-25
Publication
First Author: Sadowski M
Year: 2003
Journal: EMBO J
Title: Independent functions of yeast Pcf11p in pre-mRNA 3' end processing and in transcription termination.
Volume: 22
Issue: 9
Pages: 2167-77
Protein Domain
Type: Family
Description: Pcf11 is a subunit of an essential polyadenylation factor in Saccharomyces cerevisiae, CFIA. Pcf11 binds to Clp1, another subunit of CFIA whose interaction is responsible for maintaining a tight coupling between the Clp1 nucleotide binding subunit and the other components of the polyadenylation machinery [, ]. Pcf11 is a bifunctional protein involved in pre-mRNA 3' end processing and transcription termination [, ].
Protein
Organism: Mus musculus
Length: 1553  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1476  
Fragment?: true
Publication
First Author: Noble CG
Year: 2005
Journal: Nat Struct Mol Biol
Title: Key features of the interaction between Pcf11 CID and RNA polymerase II CTD.
Volume: 12
Issue: 2
Pages: 144-51
Allele    
Name: PCF11 cleavage and polyadenylation factor subunit; wild type
Allele Type: Not Specified
ProxyCollection
Allele  
Name: PCF11 cleavage and polyadenylation factor subunit; gene trap RRP157, BayGenomics
Allele Type: Gene trapped
Publication categories: ProxyCollection
Publication
First Author: Gross S
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I.
Volume: 98
Issue: 11
Pages: 6080-5
Allele  
Name: PCF11 cleavage and polyadenylation factor subunit; gene trap OST207987, Lexicon Genetics
Allele Type: Gene trapped
Publication categories: ProxyCollection
Allele  
Name: PCF11 cleavage and polyadenylation factor subunit; gene trap OST267717, Lexicon Genetics
Allele Type: Gene trapped
Publication categories: ProxyCollection
Allele  
Name: PCF11 cleavage and polyadenylation factor subunit; gene trap OST375724, Lexicon Genetics
Allele Type: Gene trapped
Publication categories: ProxyCollection
Allele  
Name: PCF11 cleavage and polyadenylation factor subunit; gene trap OST456677, Lexicon Genetics
Allele Type: Gene trapped
Publication categories: ProxyCollection
Allele  
Name: PCF11 cleavage and polyadenylation factor subunit; gene trap PST5967, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
Publication categories: ProxyCollection
Allele  
Name: PCF11 cleavage and polyadenylation factor subunit; gene trap EUCE0015g09, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
Publication categories: ProxyCollection
Allele
Name: PCF11 cleavage and polyadenylation factor subunit; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Publication categories: ProxyCollection
Allele
Name: PCF11 cleavage and polyadenylation factor subunit; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Publication categories: ProxyCollection
Allele  
Name: PCF11 cleavage and polyadenylation factor subunit; gene trap S13-2G1, Philippe Soriano
Allele Type: Gene trapped
Publication categories: ProxyCollection
Publication
First Author: Noble CG
Year: 2007
Journal: Nucleic Acids Res
Title: Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor.
Volume: 35
Issue: 1
Pages: 87-99
Allele  
Name: PCF11 cleavage and polyadenylation factor subunit; gene trap IST11922H9, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Publication categories: ProxyCollection
Allele  
Name: PCF11 cleavage and polyadenylation factor subunit; gene trap IST13129D10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Publication categories: ProxyCollection
Protein Domain
Type: Homologous_superfamily
Description: The C-terminal section of cleavage stimulation and termination factor CstF-64 (CSTF2) and its yeast orthologue Rna15 form a discreet structure that is crucial for mRNA 3'-end processing []. This domain interacts with Pcf11 and possibly PC4, thus linking CSTF2 to transcription, transcriptional termination, and cell growth [].
Publication
First Author: Qu X
Year: 2007
Journal: J Biol Chem
Title: The C-terminal domains of vertebrate CstF-64 and its yeast orthologue Rna15 form a new structure critical for mRNA 3'-end processing.
Volume: 282
Issue: 3
Pages: 2101-15
Publication
First Author: Dheur S
Year: 2003
Journal: EMBO J
Title: Pti1p and Ref2p found in association with the mRNA 3' end formation complex direct snoRNA maturation.
Volume: 22
Issue: 11
Pages: 2831-40
Protein Domain
Type: Domain
Description: The C-terminal section of cleavage stimulation and termination factor CstF-64 (CSTF2) and its yeast orthologue Rna15 form a discreetstructure that is crucial for mRNA 3'-end processing []. This domain interacts with Pcf11 and possibly PC4, thus linking CSTF2 to transcription, transcriptional termination, and cell growth [].Proteins containing this domain also include Pti1 protein from budding yeast. Pti1 is an essential component of CPF (cleavage and polyadenylation factor) involved in 3' end formation of snoRNA and mRNA [].
Publication
First Author: Hockert JA
Year: 2010
Journal: J Biol Chem
Title: The hinge domain of the cleavage stimulation factor protein CstF-64 is essential for CstF-77 interaction, nuclear localization, and polyadenylation.
Volume: 285
Issue: 1
Pages: 695-704
Publication
First Author: Meinhart A
Year: 2004
Journal: Nature
Title: Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors.
Volume: 430
Issue: 6996
Pages: 223-6
Protein Domain
Type: Domain
Description: The C-terminal domain (CTD) of the large subunit of RNA polymerase II is aplatform for mRNA processing factors and links gene transcription to mRNAcapping, splicing and polyadenylation. CTD recognition is dependent on thephosphorylation state of the CTD itself, which varies during the course oftranscription but has also been linked to the isomerization state of the CTD'sproline residues. Several RNA-processing factors recognise the CTD by means ofa conserved CTD-interacting domain (CID). Factors with CID domains include theserine/arginine-rich-like factors SCAF4 and SCAF8, Nrd1 (which is implicatedin polyadenylation-independent RNA 3'-end formation) and Pcf11. Pcf11 is aconserved and essential subunit of the yeast cleavage factor 1A, which isrequired for 3'-RNA processing and transcription termination [, ].The CID domain is a right-handed superhelix of eight alpha-helices forming acompact domain. The CID fold closely resembles that of VHSdomains and is related to armadillo-repeat proteins , except for the two amino-terminal helices. Amino acid residuesin the hydrophobic core of the domain are highly conserved across CID domains[, ].
Protein
Organism: Mus musculus
Length: 312  
Fragment?: false
Protein
Organism: Mus musculus
Length: 326  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1469  
Fragment?: false
Protein
Organism: Mus musculus
Length: 632  
Fragment?: false
Protein
Organism: Mus musculus
Length: 251  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1641  
Fragment?: true
Protein
Organism: Mus musculus
Length: 533  
Fragment?: true
Protein
Organism: Mus musculus
Length: 279  
Fragment?: true
Protein
Organism: Mus musculus
Length: 514  
Fragment?: true
Protein
Organism: Mus musculus
Length: 159  
Fragment?: false
Protein
Organism: Mus musculus
Length: 473  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1553  
Fragment?: false
Protein
Organism: Mus musculus
Length: 325  
Fragment?: false