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Search results 1 to 100 out of 2458 for Pcna

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Type Details Score
Gene
5111 | PCNA
Type: gene
Organism: human
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Gene
458081 | PCNA
Type: gene
Organism: chimpanzee
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Gene
515499 | PCNA
Type: gene
Organism: cattle
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Gene
373984 | PCNA
Type: gene
Organism: chicken
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Gene
30678 | pcna
Type: gene
Organism: zebrafish
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Gene
718006 | PCNA
Type: gene
Organism: macaque, rhesus
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Gene
493302 | pcna
Type: gene
Organism: frog, western clawed
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Gene
25737 | Pcna
Type: gene
Organism: rat
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Gene
477166 | PCNA
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:97503 | Pcna
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:6476670
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910625
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:7432402
Age: embryonic day 17.5
Image: 2B Pcna
Note: Co-expressed with Cdc5l in ~75% of chondrocytes.
Specimen Label: 2B Pcna
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6476670
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910625
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:7432402
Age: embryonic day 17.5
Image: 2C Pcna
Note: Co-expressed with Cdc5l in ~75% of chondrocytes.
Specimen Label: 2C Pcna
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6476670
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910625
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:7432401
Age: embryonic day 17.5
Image: 2A Pcna
Note: Expression in round chondrocytes of humeral head .
Specimen Label: 2A Pcna
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6476670
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7432401
Age: embryonic day 17.5
Image: 2A Pcna
Note: Expression in columnar proliferating chondrocytes.
Specimen Label: 2A Pcna
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1314837
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-08
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:160699
Stage: TS09
Assay Id: MGI:7284266
Age: embryonic day 6.5
Image: 3B Nczf-/- PCNA
Specimen Label: 3B Nczf-/- PCNA
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1314837
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160699
Pattern: Widespread
Stage: TS09
Assay Id: MGI:7284266
Age: embryonic day 6.5
Image: 3B Nczf+/+ PCNA
Note: Expression throughout epiblast.
Specimen Label: 3B Nczf+/+ PCNA
Detected: true
Specimen Num: 1
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Gene
9768 | PCLAF
Type: gene
Organism: human
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Gene
100302739 | PCNA-AS1
Type: gene
Organism: human
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GO Term
GO:0043626 | PCNA complex
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Gene
105682749 | CCEPR
Type: gene
Organism: human
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Publication
35628489 | J:325280
 
First Author: Wang YL
Year: 2022
Journal: Int J Mol Sci
Title: The Functions of PCNA in Tumor Stemness and Invasion.
Volume: 23
Issue: 10
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Publication
19023449 | J:142927
 
First Author: Chen X
Year: 2008
Journal: Mol Vis
Title: PCNA interacts with Prox1 and represses its transcriptional activity.
Volume: 14
Pages: 2076-86
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GXD Expression
GXD Expression
   
Probe: MGI:1314837
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6358710
Age: embryonic day 15.5
Specimen Label: 2B Control PCNA
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1314837
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6358710
Age: embryonic day 15.5
Specimen Label: 2B Xrcc1 Nes-Cre PCNA
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:1314837
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6358710
Age: embryonic day 15.5
Specimen Label: 2B Pnkp Nes-Cre PCNA
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:1314837
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6358710
Age: embryonic day 13.5
Specimen Label: 6C control PCNA
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:1314837
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6358710
Age: embryonic day 13.5
Specimen Label: 6C Pnkp Neo/Neo PCNA
Detected: true
Specimen Num: 5
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Protein
P17918
Organism: Mus musculus/domesticus
Length: 261  
Fragment?: false
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GO Term
GO:0090618 | DNA clamp unloading
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Publication
8968049 | J:37955
First Author: Woloschak GE
Year: 1996
Journal: Carcinogenesis
Title: Regulation of thymus PCNA expression is altered in radiation-sensitive wasted mice.
Volume: 17
Issue: 11
Pages: 2357-65
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Publication
18854411 | J:141098
First Author: Roa S
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression.
Volume: 105
Issue: 42
Pages: 16248-53
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Publication
7911661 | J:18660
First Author: Charollais RH
Year: 1994
Journal: Biochem Biophys Res Commun
Title: Introns determine the time of appearance of PCNA mRNA in 3T3 cells stimulated by growth factors.
Volume: 201
Issue: 2
Pages: 841-7
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Publication
22393258 | J:185754
First Author: Postnikov YV
Year: 2012
Journal: Mol Cell Biol
Title: The nucleosome binding protein HMGN1 interacts with PCNA and facilitates its binding to chromatin.
Volume: 32
Issue: 10
Pages: 1844-54
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Publication
15890234 | J:98388
First Author: Motiwale L
Year: 2005
Journal: Cancer Lett
Title: Mouse skin tumor promotion by sodium arsenate is associated with enhanced PCNA expression.
Volume: 223
Issue: 1
Pages: 27-35
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GXD Expression
GXD Expression
 
Probe: MGI:5140186
Assay Type: Immunohistochemistry
Annotation Date: 2011-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3514928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5140408
Age: postnatal month 2
Note: Intracellular protein was detected in the uncalcified articular cartilage in the proximal tibial head.
Specimen Label: 5B PCNA 2 mo top
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5140186
Assay Type: Immunohistochemistry
Annotation Date: 2011-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5140408
Age: postnatal month 2
Note: Proximal tibial head samples were used.
Specimen Label: 5B PCNA 2 mo bottom
Detected: true
Specimen Num: 2
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Publication
21931560 | J:177283
First Author: Hendel A
Year: 2011
Journal: PLoS Genet
Title: PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells.
Volume: 7
Issue: 9
Pages: e1002262
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Publication
21383776 | J:317232
First Author: Zheng L
Year: 2011
Journal: Cell Res
Title: Fen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancer.
Volume: 21
Issue: 7
Pages: 1052-67
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Publication
21269891 | J:177630
First Author: Krijger PH
Year: 2011
Journal: DNA Repair (Amst)
Title: HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: existence of an alternative E3 ligase.
Volume: 10
Issue: 4
Pages: 438-44
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Gene
300795 | Pclaf
Type: gene
Organism: rat
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Gene
540737 | PCLAF
Type: gene
Organism: cattle
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Gene
100614685 | PCLAF
Type: gene
Organism: chimpanzee
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Gene
100333229 | pclaf
Type: gene
Organism: zebrafish
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Gene
100423080 | PCLAF
Type: gene
Organism: macaque, rhesus
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Gene
101748248 | PCLAF
Type: gene
Organism: chicken
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Gene
448713 | pclaf
Type: gene
Organism: frog, western clawed
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Gene
106557458 | PCLAF
Type: gene
Organism: dog, domestic
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GXD Expression
GXD Expression
 
Probe: MGI:7336714
Assay Type: Immunohistochemistry
Annotation Date: 2022-09-20
Strength: Present
Sex: Female
Emaps: EMAPS:1760628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7336727
Age: postnatal week 8-11
Note: Expression of Pcna in female mutant mice did not significantly differ from female wild type mice.
Specimen Label: not shown female IL15ra-/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:1314837
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1792322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6287290
Age: embryonic day 14.5
Note: Authors state that Pcna expression copied that of Ki67 (see assay MGI:6287285).
Specimen Label: E14.5 not shown
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1314837
Assay Type: Immunohistochemistry
Annotation Date: 2019-04-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1792323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6287290
Age: embryonic day 15.5
Note: Authors state that Pcna expression copied that of Ki67 (see assay MGI:6287285).
Specimen Label: E15.5 not shown
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1314837
Assay Type: Immunohistochemistry
Annotation Date: 2019-02-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6276638
Age: embryonic day 12.5
Note: Expression was detected in dividing cells, mainly from G1-phase through S-phase. Many cells in the subventricular zone were co-labelled with Pcna and Cux2.
Specimen Label: 4A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5700543
Assay Type: Immunohistochemistry
Annotation Date: 2016-01-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1668819
Pattern: Widespread
Stage: TS19
Assay Id: MGI:5701415
Age: embryonic day 11.5
Note: Expressed in almost all atrial cells, but only a few of the cells of the myocardial sinus horns revealed PCNA expression.
Specimen Label: 3P/Q/S
Detected: true
Specimen Num: 1
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Protein Coding Gene
MGI:1915276 | Pclaf
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
16340005 | J:126595
First Author: Langerak P
Year: 2005
Journal: Nucleic Acids Res
Title: Rapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA.
Volume: 33
Issue: 22
Pages: e188
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Publication
34433039 | J:311101
First Author: Wang YL
Year: 2021
Journal: Cell Rep
Title: Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA.
Volume: 36
Issue: 8
Pages: 109537
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Protein Domain
IPR000730 | Pr_cel_nuc_antig
Type: Family
Description: Proliferating cell nuclear antigen (PCNA), or cyclin, is a non-histone acidic nuclear protein []that plays a key role in the control of eukaryotic DNA replication []. It acts as a co-factor for DNA polymerase delta, which is responsible for leading strand DNAreplication []. The sequence of PCNA is well conserved between plants and animals, indicating a strong selective pressure for structure conservation, and suggesting that this type of DNA replication mechanism is conserved throughout eukaryotes []. In Saccharomyces cerevisiae (Baker's yeast), POL30, is associated with polymerase III, the yeast analog of polymerase delta.Homologues of PCNA have also been identified in the archaea (known as DNA polymerase sliding clamp) [, ]and in Paramecium bursaria Chlorella virus 1 (PBCV-1) and in nuclear polyhedrosis viruses.
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Publication
32814343 | J:297409
First Author: Kulkarni DS
Year: 2020
Journal: Nature
Title: PCNA activates the MutLγ endonuclease to promote meiotic crossing over.
Volume: 586
Issue: 7830
Pages: 623-627
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Publication
21415862 | J:186955
First Author: Logette E
Year: 2011
Journal: Cell Death Differ
Title: PIDD orchestrates translesion DNA synthesis in response to UV irradiation.
Volume: 18
Issue: 6
Pages: 1036-45
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Publication
16857592 | J:111225
First Author: Guo C
Year: 2006
Journal: Mol Cell
Title: REV1 protein interacts with PCNA: significance of the REV1 BRCT domain in vitro and in vivo.
Volume: 23
Issue: 2
Pages: 265-71
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Publication
1353383 | J:1305
First Author: Abbott C
Year: 1992
Journal: Mamm Genome
Title: The gene for proliferating cell nuclear antigen (Pcna) maps to mouse chromosome 2.
Volume: 3
Issue: 5
Pages: 286-9
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Publication
1726365 | J:22042
First Author: Shipman-Appasamy PM
Year: 1991
Journal: DNA Seq
Title: Nucleotide sequence of murine PCNA: interspecies comparison of the cDNA and the 5' flanking region of the gene.
Volume: 2
Issue: 3
Pages: 181-91
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Publication
1674997 | J:11220
First Author: Yamaguchi M
Year: 1991
Journal: Nucleic Acids Res
Title: Molecular cloning and structural analysis of mouse gene and pseudogenes for proliferating cell nuclear antigen.
Volume: 19
Issue: 9
Pages: 2403-10
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Publication
23201573 | J:193874
First Author: Lo YH
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Phosphorylation at tyrosine 114 of Proliferating Cell Nuclear Antigen (PCNA) is required for adipogenesis in response to high fat diet.
Volume: 430
Issue: 1
Pages: 43-8
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Publication
28761001 | J:243839
First Author: Pilzecker B
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: DNA damage tolerance in hematopoietic stem and progenitor cells in mice.
Volume: 114
Issue: 33
Pages: E6875-E6883
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Publication
7902277 | J:71314
First Author: Matsuoka S
Year: 1993
Journal: Eur J Biochem
Title: Nucleotide sequence and promoter-specific effect of a negative regulatory region located upstream of the mouse proliferating cell nuclear antigen gene.
Volume: 218
Issue: 1
Pages: 173-81
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Publication
10891596 | J:63627
First Author: Ino H
Year: 2000
Journal: Brain Res Mol Brain Res
Title: Expression of proliferating cell nuclear antigen (PCNA) in the adult and developing mouse nervous system.
Volume: 78
Issue: 1-2
Pages: 163-74
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Publication
7910946 | J:18505
First Author: Huang D
Year: 1994
Journal: Mol Cell Biol
Title: Promoter activity of the proliferating-cell nuclear antigen gene is associated with inducible CRE-binding proteins in interleukin 2-stimulated T lymphocytes.
Volume: 14
Issue: 6
Pages: 4233-43
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Publication
9038370 | J:38496
First Author: Kelman Z
Year: 1997
Journal: Oncogene
Title: PCNA: structure, functions and interactions.
Volume: 14
Issue: 6
Pages: 629-40
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Publication
20975039 | J:177022
First Author: Witko-Sarsat V
Year: 2010
Journal: J Exp Med
Title: Proliferating cell nuclear antigen acts as a cytoplasmic platform controlling human neutrophil survival.
Volume: 207
Issue: 12
Pages: 2631-45
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Publication
18162470 | J:132156
First Author: Guo C
Year: 2008
Journal: J Biol Chem
Title: Requirements for the interaction of mouse Polkappa with ubiquitin and its biological significance.
Volume: 283
Issue: 8
Pages: 4658-64
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Publication
10681000 | J:59095
First Author: Takai N
Year: 1999
Journal: Reprod Fertil Dev
Title: Expression of polo-like kinase (PLK) in the mouse placenta and ovary.
Volume: 11
Issue: 1
Pages: 31-5
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Publication
20097160 | J:157857
First Author: Min H
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Proliferating cell nuclear antigen (Pcna) as a direct downstream target gene of Hoxc8.
Volume: 392
Issue: 4
Pages: 543-7
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Publication
22679001 | J:191344
First Author: Zhang X
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Cytosolic sulfotransferase 2B1b promotes hepatocyte proliferation gene expression in vivo and in vitro.
Volume: 303
Issue: 3
Pages: G344-55
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Publication
9042536 | J:39032
First Author: Vela Hernández JM
Year: 1997
Journal: Brain Res
Title: Abnormal expression of the proliferating cell nuclear antigen (PCNA) in the spinal cord of the hypomyelinated Jimpy mutant mice.
Volume: 747
Issue: 1
Pages: 130-9
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Publication
21253613 | J:180831
First Author: Xu B
Year: 2011
Journal: PLoS One
Title: Proliferating cell nuclear antigen (PCNA) regulates primordial follicle assembly by promoting apoptosis of oocytes in fetal and neonatal mouse ovaries.
Volume: 6
Issue: 1
Pages: e16046
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Publication
21304913 | J:169551
First Author: Wit N
Year: 2011
Journal: PLoS One
Title: Lysine residue 185 of Rad1 is a topological but not a functional counterpart of lysine residue 164 of PCNA.
Volume: 6
Issue: 1
Pages: e16669
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Publication
12509454 | J:127027
First Author: Engel FB
Year: 2003
Journal: Mol Cell Biol
Title: p21(CIP1) Controls proliferating cell nuclear antigen level in adult cardiomyocytes.
Volume: 23
Issue: 2
Pages: 555-65
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Publication
17283043 | J:121378
First Author: Zheng L
Year: 2007
Journal: Mol Cell Biol
Title: Disruption of the FEN-1/PCNA interaction results in DNA replication defects, pulmonary hypoplasia, pancytopenia, and newborn lethality in mice.
Volume: 27
Issue: 8
Pages: 3176-86
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Publication
35799276 | J:338152
First Author: Wang W
Year: 2022
Journal: Stem Cell Res Ther
Title: KAP1 phosphorylation promotes the survival of neural stem cells after ischemia/reperfusion by maintaining the stability of PCNA.
Volume: 13
Issue: 1
Pages: 290
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Publication
35101837 | J:320853
 
First Author: Mitomo K
Year: 2022
Journal: Arch Oral Biol
Title: Hypoplasia of medial pterygoid process in sphenoid bone relates to decreased mesenchymal cell proliferation in the Runx2-haploinsufficient cleidocranial dysplasia mouse model.
Volume: 135
Pages: 105358
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Publication
18265020 | J:132131
First Author: Barton KM
Year: 2008
Journal: Dev Dyn
Title: Expression patterns and cell cycle profiles of PCNA, MCM6, cyclin D1, cyclin A2, cyclin B1, and phosphorylated histone H3 in the developing mouse retina.
Volume: 237
Issue: 3
Pages: 672-82
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Publication
11022036 | J:117431
First Author: Azam N
Year: 2001
Journal: J Biol Chem
Title: Interaction of CR6 (GADD45gamma ) with proliferating cell nuclear antigen impedes negative growth control.
Volume: 276
Issue: 4
Pages: 2766-74
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Publication
14703996 | J:88220
First Author: Amasaki H
Year: 2003
Journal: Ann Anat
Title: Distributional changes of BrdU, PCNA, E2F1 and PAL31 molecules in developing murine palatal rugae.
Volume: 185
Issue: 6
Pages: 517-23
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Publication
8645597 | J:29932
First Author: Fedtsova NG
Year: 1995
Journal: Mech Dev
Title: Brn-3.0 expression identifies early post-mitotic CNS neurons and sensory neural precursors.
Volume: 53
Issue: 3
Pages: 291-304
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Publication
15169903 | J:91026
First Author: Angus SP
Year: 2004
Journal: Mol Cell Biol
Title: RB reversibly inhibits DNA replication via two temporally distinct mechanisms.
Volume: 24
Issue: 12
Pages: 5404-20
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Publication
16611994 | J:108367
First Author: Bi X
Year: 2006
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