|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 92 out of 92 for Pcsk4

0.024s

Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Gyamera-Acheampong C
Year: 2006
Journal: Biol Reprod
Title: Sperm from mice genetically deficient for the PCSK4 proteinase exhibit accelerated capacitation, precocious acrosome reaction, reduced binding to egg zona pellucida, and impaired fertilizing ability.
Volume: 74
Issue: 4
Pages: 666-73
Publication
First Author: Mbikay M
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Impaired fertility in mice deficient for the testicular germ-cell protease PC4.
Volume: 94
Issue: 13
Pages: 6842-6
Publication
First Author: Gyamera-Acheampong C
Year: 2010
Journal: Fertil Steril
Title: PCSK4-null sperm display enhanced protein tyrosine phosphorylation and ADAM2 proteolytic processing during in vitro capacitation.
Volume: 93
Issue: 4
Pages: 1112-23
Publication
First Author: Iamsaard S
Year: 2011
Journal: J Cell Physiol
Title: Enzymatic activity of sperm proprotein convertase is important for mammalian fertilization.
Volume: 226
Issue: 11
Pages: 2817-26
Publication
First Author: Tardif S
Year: 2012
Journal: Mol Hum Reprod
Title: Alteration in the processing of the ACRBP/sp32 protein and sperm head/acrosome malformations in proprotein convertase 4 (PCSK4) null mice.
Volume: 18
Issue: 6
Pages: 298-307
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Nakayama K
Year: 1992
Journal: J Biol Chem
Title: Identification of the fourth member of the mammalian endoprotease family homologous to the yeast Kex2 protease. Its testis-specific expression.
Volume: 267
Issue: 9
Pages: 5897-900
Publication
First Author: Mbikay M
Year: 1994
Journal: Genomics
Title: Structure of the gene for the testis-specific proprotein convertase 4 and of its alternate messenger RNA isoforms.
Volume: 20
Issue: 2
Pages: 231-7
GXD Expression    
Probe: MGI:4947658
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:4947689
Age: embryonic day 1.0
Image: 2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4947658
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:4947689
Age: embryonic day 2.0
Image: 2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4947658
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:4947689
Age: embryonic day 3.0
Image: 2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:4947658
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:4947689
Age: embryonic day 0.5
Image: 2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4947658
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:4947689
Age: embryonic day 3.5
Image: 2
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:4947658
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:4947689
Age: postnatal
Image: 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4947658
Assay Type: RT-PCR
Annotation Date: 2011-04-22
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:4947689
Age: postnatal
Image: 2
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3584967
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3586285
Age: embryonic day 18.0
Note: Expression was detected in the outer neuroblastic layer.
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3584967
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3586285
Age: postnatal day 0-1
Note: Expression was detected in the outer neuroblastic layer.
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3584967
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3586285
Age: postnatal day 2-3
Note: Expression was detected in the outer neuroblastic layer.
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3584967
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586285
Age: postnatal day 4-5
Note: Expression was detected in the outer neuroblastic layer.
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3584967
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586285
Age: postnatal day 6-7
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3584967
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586285
Age: postnatal day 8-10
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:3584967
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3586285
Age: postnatal adult
Note: Expression was detected in the inner segment.
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:3584967
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1859224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3586285
Age: embryonic day 16.0
Note: Expression was detected in the outer neuroblastic layer.
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693173
Age: postnatal adult
Image: JAX_1800114
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3584967
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:3574228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3586285
Age: postnatal adult
Note: Expression was detected in bipolar cells.
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693173
Age: postnatal adult
Image: JAX_1800113
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693173
Age: postnatal adult
Image: JAX_1800112
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3584967
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3586285
Age: embryonic day 14.0
Note: Expression was detected in the outer neuroblastic layer.
Detected: true
Specimen Num: 1
Publication
First Author: Tadros H
Year: 2001
Journal: J Reprod Immunol
Title: The testicular germ-cell protease PC4 is also expressed in macrophage-like cells of the ovary.
Volume: 49
Issue: 2
Pages: 133-52
Publication
First Author: Torii S
Year: 1993
Journal: FEBS Lett
Title: Localization of Kex2-like processing endoproteases, furin and PC4, within mouse testis by in situ hybridization.
Volume: 316
Issue: 1
Pages: 12-6
Publication
First Author: Seidah NG
Year: 1999
Journal: Brain Res
Title: Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides.
Volume: 848
Issue: 1-2
Pages: 45-62
Publication
First Author: Knopp EA
Year: 1999
Journal: Mamm Genome
Title: Murine phospholipid hydroperoxide glutathione peroxidase: cDNA sequence, tissue expression, and mapping.
Volume: 10
Issue: 6
Pages: 601-5
Publication
First Author: Steiner DF
Year: 1992
Journal: J Biol Chem
Title: The new enzymology of precursor processing endoproteases.
Volume: 267
Issue: 33
Pages: 23435-8
Publication
First Author: Seidah NG
Year: 1994
Journal: Biochimie
Title: The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.
Volume: 76
Issue: 3-4
Pages: 197-209
Publication
First Author: Mbikay M
Year: 1995
Journal: Genomics
Title: Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human.
Volume: 26
Issue: 1
Pages: 123-9
Publication
First Author: Constam DB
Year: 1999
Journal: J Cell Biol
Title: Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.
Volume: 144
Issue: 1
Pages: 139-49
Publication
First Author: Constam DB
Year: 1996
Journal: J Cell Biol
Title: SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.
Volume: 134
Issue: 1
Pages: 181-91
Publication
First Author: St Germain C
Year: 2005
Journal: Mol Reprod Dev
Title: Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.
Volume: 72
Issue: 4
Pages: 483-93
Publication
First Author: Puttagunta R
Year: 2000
Journal: Genome Res
Title: Comparative maps of human 19p13.3 and mouse chromosome 10 allow identification of sequences at evolutionary breakpoints.
Volume: 10
Issue: 9
Pages: 1369-80
Publication
First Author: Scavuzzo MA
Year: 2018
Journal: Cell Rep
Title: Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA.
Volume: 25
Issue: 13
Pages: 3811-3827.e7
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication          
First Author: MGD Nomenclature Committee
Year: 1995
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication
First Author: Gyamera-Acheampong C
Year: 2011
Journal: Mol Cell Biochem
Title: The precursor to the germ cell-specific PCSK4 proteinase is inefficiently activated in transfected somatic cells: evidence of interaction with the BiP chaperone.
Volume: 348
Issue: 1-2
Pages: 43-52