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Search results 1 to 93 out of 93 for Pdcd6

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
10016 | PDCD6
Type: gene
Organism: human
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Gene
493366 | pdcd6
Type: gene
Organism: frog, western clawed
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Gene
308061 | Pdcd6
Type: gene
Organism: rat
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Gene
609549 | PDCD6
Type: gene
Organism: dog, domestic
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Gene
471813 | PDCD6
Type: gene
Organism: chimpanzee
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Gene
100125927 | PDCD6
Type: gene
Organism: cattle
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Gene
420988 | PDCD6
Type: gene
Organism: chicken
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Gene
393925 | pdcd6
Type: gene
Organism: zebrafish
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Gene
723043 | PDCD6
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:109283 | Pdcd6
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
728613 | PDCD6P1
Type: gene
Organism: human
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Gene
102467073 | PDCD6-DT
Type: gene
Organism: human
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Publication
39578445 | J:359875
First Author: Sun L
Year: 2024
Journal: Nat Commun
Title: PDCD6 regulates lactate metabolism to modulate LC3-associated phagocytosis and antibacterial defense.
Volume: 15
Issue: 1
Pages: 10157
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Protein Coding Gene
MGP_CAROLIEiJ_G0018719 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020762 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020718 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020692 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020715 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020509 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_109283 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021152 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020026 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020468 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020593 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020573 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020601 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021191 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019780 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020084 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015799 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019603 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
2736249 | J:37099
First Author: Kageyama H
Year: 1989
Journal: Biochim Biophys Acta
Title: A partial cDNA for a novel protein which has a typical E-F hand structure.
Volume: 1008
Issue: 2
Pages: 255-7
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Publication
12024023 | J:76789
First Author: Jang IK
Year: 2002
Journal: Mol Cell Biol
Title: Apoptosis-linked gene 2-deficient mice exhibit normal T-cell development and function.
Volume: 22
Issue: 12
Pages: 4094-100
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Publication
27541325 | J:240322
First Author: Tanner JJ
Year: 2016
Journal: Biochemistry
Title: EF5 Is the High-Affinity Mg(2+) Site in ALG-2.
Volume: 55
Issue: 36
Pages: 5128-41
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Publication
8084497 | J:19534
First Author: Hirota M
Year: 1994
Journal: Neurosci Lett
Title: pS2 gene especially expressed in the late G1/S phase of mouse astrocytes.
Volume: 171
Issue: 1-2
Pages: 49-51
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Publication
10360947 | J:55623
First Author: Lo KW
Year: 1999
Journal: Biochemistry
Title: Apoptosis-linked gene product ALG-2 is a new member of the calpain small subunit subfamily of Ca2+-binding proteins.
Volume: 38
Issue: 23
Pages: 7498-508
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Publication
12445461 | J:80591
First Author: Krebs J
Year: 2002
Journal: Biochim Biophys Acta
Title: ALG-2: a Ca2+ -binding modulator protein involved in cell proliferation and in cell death.
Volume: 1600
Issue: 1-2
Pages: 68-73
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Publication
17214967 | J:127172
First Author: la Cour JM
Year: 2007
Journal: Biochem Biophys Res Commun
Title: ALG-2 oscillates in subcellular localization, unitemporally with calcium oscillations.
Volume: 353
Issue: 4
Pages: 1063-7
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Publication
10200558 | J:53664
First Author: Missotten M
Year: 1999
Journal: Cell Death Differ
Title: Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptosis-linked-gene 2 (ALG-2) protein.
Volume: 6
Issue: 2
Pages: 124-9
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Publication
8560270 | J:33763
First Author: Vito P
Year: 1996
Journal: Science
Title: Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3.
Volume: 271
Issue: 5248
Pages: 521-5
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Publication
11606059 | J:161035
First Author: Jung YS
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Apoptosis-linked gene 2 binds to the death domain of Fas and dissociates from Fas during Fas-mediated apoptosis in Jurkat cells.
Volume: 288
Issue: 2
Pages: 420-6
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Publication
17889823 | J:201254
First Author: Draeby I
Year: 2007
Journal: Arch Biochem Biophys
Title: The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane.
Volume: 467
Issue: 1
Pages: 87-94
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Publication
9160754 | J:40365
First Author: Shen J
Year: 1997
Journal: Cell
Title: Skeletal and CNS defects in Presenilin-1-deficient mice.
Volume: 89
Issue: 4
Pages: 629-39
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Publication
10858458 | J:62902
First Author: Chen B
Year: 2000
Journal: J Biol Chem
Title: The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes.
Volume: 275
Issue: 25
Pages: 19275-81
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Publication
14561754 | J:87334
First Author: Rao RV
Year: 2004
Journal: J Biol Chem
Title: Molecular components of a cell death pathway activated by endoplasmic reticulum stress.
Volume: 279
Issue: 1
Pages: 177-87
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Publication
12522145 | J:177167
First Author: Tomsig JL
Year: 2003
Journal: J Biol Chem
Title: Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.
Volume: 278
Issue: 12
Pages: 10048-54
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Publication
11591653 | J:103507
First Author: Suzuki H
Year: 2001
Journal: Genome Res
Title: Protein-protein interaction panel using mouse full-length cDNAs.
Volume: 11
Issue: 10
Pages: 1758-65
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Pdcd6<em1Smoc> | MGI:7291573
Name: programmed cell death 6; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6429337 | C57BL/6JSmoc-Pdcd6<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
17045351 | -
First Author: Montaville P
Year: 2006
Journal: Biochim Biophys Acta
Title: Nuclear translocation of the calcium-binding protein ALG-2 induced by the RNA-binding protein RBM22.
Volume: 1763
Issue: 11
Pages: 1335-43
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Publication
9528778 | -
First Author: Xu D
Year: 1998
Journal: Mol Cell Biol
Title: Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing.
Volume: 18
Issue: 4
Pages: 2055-66
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Protein Domain
IPR039171 | Cwc2/Slt11
Type: Family
Description: This entry contains proteins involved in the first step of pre-mRNA splicing to remove introns. Splicing is performed by the spliceosome, which is a complex of snRNAs U1, U2, U4, U5, and U6 and proteins such as pre-mRNA-processing factor 19 (Prp19). The yeast protein Cwc2 contains motifs known to bind RNA, a zinc finger and an RNA recognition motif. Because mutations in the gene are lethal and lead to accumulation of pre-mRNA, and reduced levels of U1, U4, U5 and U6 snRNAs and U4/U6 snRNA complex levels, Cwc2 has been proposed to link the Prp19 complex to the spliceosome during pre-mRNA splicing []. Because Cwc2 is at the spliceosome catalytic centre, it induces an active conformation of the spliceosome's catalytic RNA elements []. Cwc2 is a component of the CWC complex []. The human homologue, known as RBM22 [], also translocates the protein SLU7 from the nucleus to the cytoplasm or vice versa in the case of the calcium-binding protein PDCD6 [].Also included in this entry is the pre-mRNA-splicing factor Slt11 (also known as Ecm2) [].
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Protein
A2RT18
Organism: Mus musculus/domesticus
Length: 1139  
Fragment?: false
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Protein
F6WNY1
Organism: Mus musculus/domesticus
Length: 1150  
Fragment?: true
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Protein
Q99MW8
Organism: Mus musculus/domesticus
Length: 1139  
Fragment?: false
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Publication
22246180 | -
First Author: Rasche N
Year: 2012
Journal: EMBO J
Title: Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre.
Volume: 31
Issue: 6
Pages: 1591-604
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Publication
19435883 | -
First Author: McGrail JC
Year: 2009
Journal: Nucleic Acids Res
Title: The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing.
Volume: 37
Issue: 13
Pages: 4205-17
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Protein
Q8BHS3
Organism: Mus musculus/domesticus
Length: 420  
Fragment?: false
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Publication
11884590 | -
First Author: Ohi MD
Year: 2002
Journal: Mol Cell Biol
Title: Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.
Volume: 22
Issue: 7
Pages: 2011-24
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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