Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Hart AW |
Year: |
2005 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Genotype-phenotype correlation of mouse pde6b mutations. |
Volume: |
46 |
Issue: |
9 |
Pages: |
3443-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Muradov H |
Year: |
2012 |
Journal: |
Vision Res |
Title: |
Atypical retinal degeneration 3 in mice is caused by defective PDE6B pre-mRNA splicing. |
Volume: |
57 |
|
Pages: |
1-8 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
61
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Allocca M |
Year: |
2011 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
AAV-mediated gene replacement, either alone or in combination with physical and pharmacological agents, results in partial and transient protection from photoreceptor degeneration associated with betaPDE deficiency. |
Volume: |
52 |
Issue: |
8 |
Pages: |
5713-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamoah A |
Year: |
2023 |
Journal: |
Cells |
Title: |
Early Alterations of RNA Binding Protein (RBP) Homeostasis and ER Stress-Mediated Autophagy Contributes to Progressive Retinal Degeneration in the rd10 Mouse Model of Retinitis Pigmentosa (RP). |
Volume: |
12 |
Issue: |
7 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Sánchez-Cruz A |
Year: |
2018 |
Journal: |
Mol Neurodegener |
Title: |
Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa. |
Volume: |
13 |
Issue: |
1 |
Pages: |
19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vidal-Gil L |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
Poly ADP ribosylation and extracellular vesicle activity in rod photoreceptor degeneration. |
Volume: |
9 |
Issue: |
1 |
Pages: |
3758 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berkowitz BA |
Year: |
2020 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Rod Photoreceptor Neuroprotection in Dark-Reared Pde6brd10 Mice. |
Volume: |
61 |
Issue: |
13 |
Pages: |
14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang B |
Year: |
2007 |
Journal: |
Vision Res |
Title: |
Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene. |
Volume: |
47 |
Issue: |
5 |
Pages: |
624-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang T |
Year: |
2018 |
Journal: |
J Biol Chem |
Title: |
The PDE6 mutation in the rd10 retinal degeneration mouse model causes protein mislocalization and instability and promotes cell death through increased ion influx. |
Volume: |
293 |
Issue: |
40 |
Pages: |
15332-15346 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheong SK |
Year: |
2018 |
Journal: |
PLoS One |
Title: |
All-optical recording and stimulation of retinal neurons in vivo in retinal degeneration mice. |
Volume: |
13 |
Issue: |
3 |
Pages: |
e0194947 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barone I |
Year: |
2014 |
Journal: |
Mol Vis |
Title: |
Long-term preservation of cone photoreceptors and visual acuity in rd10 mutant mice exposed to continuous environmental enrichment. |
Volume: |
20 |
|
Pages: |
1545-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Corrochano S |
Year: |
2008 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Attenuation of vision loss and delay in apoptosis of photoreceptors induced by proinsulin in a mouse model of retinitis pigmentosa. |
Volume: |
49 |
Issue: |
9 |
Pages: |
4188-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gargini C |
Year: |
2007 |
Journal: |
J Comp Neurol |
Title: |
Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: a morphological and ERG study. |
Volume: |
500 |
Issue: |
2 |
Pages: |
222-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kutsyr O |
Year: |
2021 |
Journal: |
Sci Rep |
Title: |
Retinitis pigmentosa is associated with shifts in the gut microbiome. |
Volume: |
11 |
Issue: |
1 |
Pages: |
6692 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang J |
Year: |
2020 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Comparison of Sigma 1 Receptor Ligands SA4503 and PRE084 to (+)-Pentazocine in the rd10 Mouse Model of RP. |
Volume: |
61 |
Issue: |
13 |
Pages: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Narcisse D |
Year: |
2021 |
Journal: |
Front Neurosci |
Title: |
Monitoring Visual Cortical Activities During Progressive Retinal Degeneration Using Functional Bioluminescence Imaging. |
Volume: |
15 |
|
Pages: |
750684 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arroba AI |
Year: |
2011 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Microglia-mediated IGF-I neuroprotection in the rd10 mouse model of retinitis pigmentosa. |
Volume: |
52 |
Issue: |
12 |
Pages: |
9124-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Della Santina L |
Year: |
2010 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Effect of HCN channel inhibition on retinal morphology and function in normal and dystrophic rodents. |
Volume: |
51 |
Issue: |
2 |
Pages: |
1016-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qin H |
Year: |
2023 |
Journal: |
J Exp Med |
Title: |
Vision rescue via unconstrained in vivo prime editing in degenerating neural retinas. |
Volume: |
220 |
Issue: |
5 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Puthussery T |
Year: |
2009 |
Journal: |
Eur J Neurosci |
Title: |
Differential loss and preservation of glutamate receptor function in bipolar cells in the rd10 mouse model of retinitis pigmentosa. |
Volume: |
29 |
Issue: |
8 |
Pages: |
1533-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jae SA |
Year: |
2013 |
Journal: |
Korean J Physiol Pharmacol |
Title: |
Electrophysiological and Histologic Evaluation of the Time Course of Retinal Degeneration in the rd10 Mouse Model of Retinitis Pigmentosa. |
Volume: |
17 |
Issue: |
3 |
Pages: |
229-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim TH |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
Longitudinal OCT and OCTA monitoring reveals accelerated regression of hyaloid vessels in retinal degeneration 10 (rd10) mice. |
Volume: |
9 |
Issue: |
1 |
Pages: |
16685 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ivanova E |
Year: |
2019 |
Journal: |
JCI Insight |
Title: |
Blood-retina barrier failure and vision loss in neuron-specific degeneration. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Berkowitz BA |
Year: |
2018 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Dark Rearing Does Not Prevent Rod Oxidative Stress In Vivo in Pde6brd10 Mice. |
Volume: |
59 |
Issue: |
3 |
Pages: |
1659-1665 |
|
•
•
•
•
•
|
Publication |
First Author: |
Phillips MJ |
Year: |
2008 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Tauroursodeoxycholic acid preservation of photoreceptor structure and function in the rd10 mouse through postnatal day 30. |
Volume: |
49 |
Issue: |
5 |
Pages: |
2148-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2018 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Light-Dependent OCT Structure Changes in Photoreceptor Degenerative rd 10 Mouse Retina. |
Volume: |
59 |
Issue: |
2 |
Pages: |
1084-1094 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chrenek MA |
Year: |
2012 |
Journal: |
Adv Exp Med Biol |
Title: |
Analysis of the RPE sheet in the rd10 retinal degeneration model. |
Volume: |
723 |
|
Pages: |
641-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weh E |
Year: |
2022 |
Journal: |
Exp Eye Res |
Title: |
Dark-reared rd10 mice experience rapid photoreceptor degeneration with short exposure to room-light during in vivo retinal imaging. |
Volume: |
215 |
|
Pages: |
108913 |
|
•
•
•
•
•
|
Publication |
First Author: |
Popova EY |
Year: |
2021 |
Journal: |
J Neurosci |
Title: |
Inhibition of Epigenetic Modifiers LSD1 and HDAC1 Blocks Rod Photoreceptor Death in Mouse Models of Retinitis Pigmentosa. |
Volume: |
41 |
Issue: |
31 |
Pages: |
6775-6792 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang Y |
Year: |
2013 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Functional principal component analysis reveals discriminating categories of retinal pigment epithelial morphology in mice. |
Volume: |
54 |
Issue: |
12 |
Pages: |
7274-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Piano I |
Year: |
2013 |
Journal: |
Eur J Neurosci |
Title: |
Cone survival and preservation of visual acuity in an animal model of retinal degeneration. |
Volume: |
37 |
Issue: |
11 |
Pages: |
1853-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Samardzija M |
Year: |
2012 |
Journal: |
Exp Eye Res |
Title: |
Activation of survival pathways in the degenerating retina of rd10 mice. |
Volume: |
99 |
|
Pages: |
17-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rincón Montes V |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Development and in vitro validation of flexible intraretinal probes. |
Volume: |
10 |
Issue: |
1 |
Pages: |
19836 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trachsel-Moncho L |
Year: |
2018 |
Journal: |
Cell Death Dis |
Title: |
Oxidative stress and autophagy-related changes during retinal degeneration and development. |
Volume: |
9 |
Issue: |
8 |
Pages: |
812 |
|
•
•
•
•
•
|
Publication |
First Author: |
Makabe K |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Microglia dynamics in retinitis pigmentosa model: formation of fundus whitening and autofluorescence as an indicator of activity of retinal degeneration. |
Volume: |
10 |
Issue: |
1 |
Pages: |
14700 |
|
•
•
•
•
•
|
Publication |
First Author: |
Garcia-Delgado AB |
Year: |
2018 |
Journal: |
CNS Neurosci Ther |
Title: |
Rasagiline delays retinal degeneration in a mouse model of retinitis pigmentosa via modulation of Bax/Bcl-2 expression. |
Volume: |
24 |
Issue: |
5 |
Pages: |
448-455 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kutsyr O |
Year: |
2020 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Gradual Increase in Environmental Light Intensity Induces Oxidative Stress and Inflammation and Accelerates Retinal Neurodegeneration. |
Volume: |
61 |
Issue: |
10 |
Pages: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barone I |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Environmental enrichment extends photoreceptor survival and visual function in a mouse model of retinitis pigmentosa. |
Volume: |
7 |
Issue: |
11 |
Pages: |
e50726 |
|
•
•
•
•
•
|
Publication |
First Author: |
Murakami Y |
Year: |
2012 |
Journal: |
Am J Pathol |
Title: |
MutT homolog-1 attenuates oxidative DNA damage and delays photoreceptor cell death in inherited retinal degeneration. |
Volume: |
181 |
Issue: |
4 |
Pages: |
1378-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Picard E |
Year: |
2010 |
Journal: |
Mol Vis |
Title: |
Overexpressed or intraperitoneally injected human transferrin prevents photoreceptor degeneration in rd10 mice. |
Volume: |
16 |
|
Pages: |
2612-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pang JJ |
Year: |
2008 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
AAV-mediated gene therapy for retinal degeneration in the rd10 mouse containing a recessive PDEbeta mutation. |
Volume: |
49 |
Issue: |
10 |
Pages: |
4278-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boatright JH |
Year: |
2006 |
Journal: |
Mol Vis |
Title: |
Tool from ancient pharmacopoeia prevents vision loss. |
Volume: |
12 |
|
Pages: |
1706-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rincón Montes V |
Year: |
2019 |
Journal: |
Front Neurosci |
Title: |
Toward a Bidirectional Communication Between Retinal Cells and a Prosthetic Device - A Proof of Concept. |
Volume: |
13 |
|
Pages: |
367 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kanan Y |
Year: |
2023 |
Journal: |
Free Radic Biol Med |
Title: |
Reduced inspired oxygen decreases retinal superoxide radicals and promotes cone function and survival in a model of retinitis pigmentosa. |
Volume: |
198 |
|
Pages: |
118-122 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guadagni V |
Year: |
2019 |
Journal: |
FASEB J |
Title: |
Rescuing cones and daylight vision in retinitis pigmentosa mice. |
Volume: |
33 |
Issue: |
9 |
Pages: |
10177-10192 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martínez-Fernández de la Cámara C |
Year: |
2015 |
Journal: |
Sci Rep |
Title: |
Adalimumab Reduces Photoreceptor Cell Death in A Mouse Model of Retinal Degeneration. |
Volume: |
5 |
|
Pages: |
11764 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakao T |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
The role of mislocalized phototransduction in photoreceptor cell death of retinitis pigmentosa. |
Volume: |
7 |
Issue: |
4 |
Pages: |
e32472 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roche SL |
Year: |
2019 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Norgestrel, a Progesterone Analogue, Promotes Significant Long-Term Neuroprotection of Cone Photoreceptors in a Mouse Model of Retinal Disease. |
Volume: |
60 |
Issue: |
8 |
Pages: |
3221-3235 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barhoum R |
Year: |
2008 |
Journal: |
Neuroscience |
Title: |
Functional and structural modifications during retinal degeneration in the rd10 mouse. |
Volume: |
155 |
Issue: |
3 |
Pages: |
698-713 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hanif AM |
Year: |
2015 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Neuroprotective Effects of Voluntary Exercise in an Inherited Retinal Degeneration Mouse Model. |
Volume: |
56 |
Issue: |
11 |
Pages: |
6839-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sukkar B |
Year: |
2023 |
Journal: |
Glia |
Title: |
Inhibition of altered Orai1 channels in Müller cells protects photoreceptors in retinal degeneration. |
Volume: |
71 |
Issue: |
11 |
Pages: |
2511-2526 |
|
•
•
•
•
•
|
Publication |
First Author: |
Benlloch-Navarro S |
Year: |
2019 |
Journal: |
J Steroid Biochem Mol Biol |
Title: |
Progesterone anti-inflammatory properties in hereditary retinal degeneration. |
Volume: |
189 |
|
Pages: |
291-301 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roche SL |
Year: |
2016 |
Journal: |
Int J Dev Biol |
Title: |
Alterations to retinal architecture prior to photoreceptor loss in a mouse model of retinitis pigmentosa. |
Volume: |
60 |
Issue: |
4-6 |
Pages: |
127-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weiss ER |
Year: |
2019 |
Journal: |
Exp Eye Res |
Title: |
Broad spectrum metabolomics for detection of abnormal metabolic pathways in a mouse model for retinitis pigmentosa. |
Volume: |
184 |
|
Pages: |
135-145 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li B |
Year: |
2019 |
Journal: |
Exp Eye Res |
Title: |
Sex-related differences in the progressive retinal degeneration of the rd10 mouse. |
Volume: |
187 |
|
Pages: |
107773 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gayet-Primo J |
Year: |
2015 |
Journal: |
Front Cell Neurosci |
Title: |
Alterations in Kainate Receptor and TRPM1 Localization in Bipolar Cells after Retinal Photoreceptor Degeneration. |
Volume: |
9 |
|
Pages: |
486 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang K |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Carnosic acid slows photoreceptor degeneration in the Pde6b(rd10) mouse model of retinitis pigmentosa. |
Volume: |
6 |
|
Pages: |
22632 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang K |
Year: |
2017 |
Journal: |
Curr Eye Res |
Title: |
Protective effect of sulforaphane against retinal degeneration in the Pde6rd10 mouse model of retinitis pigmentosa. |
Volume: |
42 |
Issue: |
12 |
Pages: |
1684-1688 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kutsyr O |
Year: |
2021 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Short-term high-fat feeding exacerbates degeneration in retinitis pigmentosa by promoting retinal oxidative stress and inflammation. |
Volume: |
118 |
Issue: |
43 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Isiegas C |
Year: |
2016 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Intravitreal Injection of Proinsulin-Loaded Microspheres Delays Photoreceptor Cell Death and Vision Loss in the rd10 Mouse Model of Retinitis Pigmentosa. |
Volume: |
57 |
Issue: |
8 |
Pages: |
3610-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yee CW |
Year: |
2018 |
Journal: |
Neuroscience |
Title: |
Atypical Expression and Activation of GluN2A- and GluN2B-Containing NMDA Receptors at Ganglion Cells during Retinal Degeneration. |
Volume: |
393 |
|
Pages: |
61-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Biswas S |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Pharmacological analysis of intrinsic neuronal oscillations in rd10 retina. |
Volume: |
9 |
Issue: |
6 |
Pages: |
e99075 |
|
•
•
•
•
•
|
Publication |
First Author: |
Santiago CP |
Year: |
2018 |
Journal: |
Mol Ther |
Title: |
A Drug-Tunable Gene Therapy for Broad-Spectrum Protection against Retinal Degeneration. |
Volume: |
26 |
Issue: |
10 |
Pages: |
2407-2417 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiang Z |
Year: |
2018 |
Journal: |
Neuropharmacology |
Title: |
Inhibition of non-NMDA ionotropic glutamate receptors delays the retinal degeneration in rd10 mouse. |
Volume: |
139 |
|
Pages: |
137-149 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oveson BC |
Year: |
2011 |
Journal: |
J Neurochem |
Title: |
Constituents of bile, bilirubin and TUDCA, protect against oxidative stress-induced retinal degeneration. |
Volume: |
116 |
Issue: |
1 |
Pages: |
144-53 |
|
•
•
•
•
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