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Search results 1 to 100 out of 777 for Pdgfb

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Wang Y
Year: 2017
Journal: Development
Title: Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity.
Volume: 144
Issue: 19
Pages: 3590-3601
Publication  
First Author: Bonney S
Year: 2018
Journal: Front Cell Neurosci
Title: Retinoic Acid Regulates Endothelial β-catenin Expression and Pericyte Numbers in the Developing Brain Vasculature.
Volume: 12
Pages: 476
Publication
First Author: Arnold TD
Year: 2014
Journal: Development
Title: Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain.
Volume: 141
Issue: 23
Pages: 4489-99
Publication
First Author: Bovay E
Year: 2018
Journal: J Exp Med
Title: Multiple roles of lymphatic vessels in peripheral lymph node development.
Volume: 215
Issue: 11
Pages: 2760-2777
Publication
First Author: Ren X
Year: 2014
Journal: Circ Res
Title: FOXF1 transcription factor is required for formation of embryonic vasculature by regulating VEGF signaling in endothelial cells.
Volume: 115
Issue: 8
Pages: 709-20
Publication
First Author: Bjarnegård M
Year: 2004
Journal: Development
Title: Endothelium-specific ablation of PDGFB leads to pericyte loss and glomerular, cardiac and placental abnormalities.
Volume: 131
Issue: 8
Pages: 1847-57
Publication
First Author: Vanlandewijck M
Year: 2015
Journal: PLoS One
Title: Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification.
Volume: 10
Issue: 11
Pages: e0143407
Publication
First Author: Ohlsson R
Year: 1999
Journal: Dev Biol
Title: PDGFB regulates the development of the labyrinthine layer of the mouse fetal placenta.
Volume: 212
Issue: 1
Pages: 124-36
Publication
First Author: Malek TR
Year: 1993
Journal: Immunogenetics
Title: The IL-2 receptor beta chain gene (Il-2rb) is closely linked to the Pdgfb locus on mouse chromosome 15.
Volume: 38
Issue: 2
Pages: 154-6
Allele
Name: transgene insertion 1, Marcus Fruttiger
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Publication
First Author: Claxton S
Year: 2008
Journal: Genesis
Title: Efficient, inducible Cre-recombinase activation in vascular endothelium.
Volume: 46
Issue: 2
Pages: 74-80
Publication
First Author: Perbellini F
Year: 2018
Journal: Cardiovasc Res
Title: Investigation of cardiac fibroblasts using myocardial slices.
Volume: 114
Issue: 1
Pages: 77-89
Genotype
Symbol: Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
Publication  
First Author: Sewduth RN
Year: 2017
Journal: Sci Signal
Title: PDZRN3 destabilizes endothelial cell-cell junctions through a PKCζ-containing polarity complex to increase vascular permeability.
Volume: 10
Issue: 464
Genotype
Symbol: Krit1/Krit1 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pdzrn3/Pdzrn3 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: C57BL/6 * C57BL/6NCrlj * CBA * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
Publication  
First Author: Issitt T
Year: 2019
Journal: iScience
Title: Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress.
Volume: 11
Pages: 205-223
Publication
First Author: Bruning U
Year: 2018
Journal: Cell Metab
Title: Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation.
Volume: 28
Issue: 6
Pages: 866-880.e15
Publication
First Author: Castillo SD
Year: 2016
Journal: Sci Transl Med
Title: Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans.
Volume: 8
Issue: 332
Pages: 332ra43
Publication
First Author: Lopez-Ramirez MA
Year: 2017
Journal: J Exp Med
Title: Thrombospondin1 (TSP1) replacement prevents cerebral cavernous malformations.
Volume: 214
Issue: 11
Pages: 3331-3346
Publication
First Author: Bats ML
Year: 2020
Journal: FASEB J
Title: Therapies targeting Frizzled-7/β-catenin pathway prevent the development of pathological angiogenesis in an ischemic retinopathy model.
Volume: 34
Issue: 1
Pages: 1288-1303
Publication
First Author: Park H
Year: 2019
Journal: Nat Commun
Title: Integrin-linked kinase controls retinal angiogenesis and is linked to Wnt signaling and exudative vitreoretinopathy.
Volume: 10
Issue: 1
Pages: 5243
Publication
First Author: Huang H
Year: 2017
Journal: EMBO J
Title: Role of glutamine and interlinked asparagine metabolism in vessel formation.
Volume: 36
Issue: 16
Pages: 2334-2352
Publication
First Author: Ham A
Year: 2014
Journal: Kidney Int
Title: Selective deletion of the endothelial sphingosine-1-phosphate 1 receptor exacerbates kidney ischemia-reperfusion injury.
Volume: 85
Issue: 4
Pages: 807-23
Publication
First Author: Fernández-Robredo P
Year: 2017
Journal: PLoS One
Title: Neuropilin 1 Involvement in Choroidal and Retinal Neovascularisation.
Volume: 12
Issue: 1
Pages: e0169865
Publication
First Author: Stone OA
Year: 2018
Journal: Nat Commun
Title: Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells.
Volume: 9
Issue: 1
Pages: 4077
Publication
First Author: Cai Y
Year: 2016
Journal: Sci Signal
Title: FOXF1 maintains endothelial barrier function and prevents edema after lung injury.
Volume: 9
Issue: 424
Pages: ra40
Publication
First Author: Bolte C
Year: 2017
Journal: Sci Rep
Title: FOXF1 transcription factor promotes lung regeneration after partial pneumonectomy.
Volume: 7
Issue: 1
Pages: 10690
Publication  
First Author: Yamamoto H
Year: 2015
Journal: Nat Commun
Title: Integrin β1 controls VE-cadherin localization and blood vessel stability.
Volume: 6
Pages: 6429
Genotype
Symbol: Jag1/Jag1 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Adgra2/Adgra2 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: 129/Sv * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Foxf1/Foxf1 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: 129 * C57BL/6 * CBA * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pfkfb3/Pfkfb3 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * CBA
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Eelen G
Year: 2018
Journal: Nature
Title: Role of glutamine synthetase in angiogenesis beyond glutamine synthesis.
Volume: 561
Issue: 7721
Pages: 63-69
Publication
First Author: van Lessen M
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Regulation of vascular endothelial growth factor receptor function in angiogenesis by numb and numb-like.
Volume: 35
Issue: 8
Pages: 1815-25
Publication
First Author: Hendrikx S
Year: 2019
Journal: Cell Rep
Title: Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2.
Volume: 26
Issue: 5
Pages: 1227-1241.e6
Publication
First Author: Stenzel D
Year: 2011
Journal: EMBO Rep
Title: Endothelial basement membrane limits tip cell formation by inducing Dll4/Notch signalling in vivo.
Volume: 12
Issue: 11
Pages: 1135-43
Publication
First Author: Gibson CC
Year: 2015
Journal: Circulation
Title: Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation.
Volume: 131
Issue: 3
Pages: 289-99
Publication
First Author: Ito TK
Year: 2014
Journal: PLoS One
Title: A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis.
Volume: 9
Issue: 7
Pages: e102186
Publication
First Author: Lopez-Ramirez MA
Year: 2019
Journal: Blood
Title: Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice.
Volume: 133
Issue: 3
Pages: 193-204
Publication
First Author: Yokoyama M
Year: 2014
Journal: Cell Rep
Title: Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity.
Volume: 7
Issue: 5
Pages: 1691-1703
Publication
First Author: Heinolainen K
Year: 2017
Journal: Circ Res
Title: VEGFR3 Modulates Vascular Permeability by Controlling VEGF/VEGFR2 Signaling.
Volume: 120
Issue: 9
Pages: 1414-1425
Publication
First Author: Raimondi C
Year: 2014
Journal: J Exp Med
Title: Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells.
Volume: 211
Issue: 6
Pages: 1167-83
Publication
First Author: Steri V
Year: 2014
Journal: Circ Res
Title: Acute depletion of endothelial β3-integrin transiently inhibits tumor growth and angiogenesis in mice.
Volume: 114
Issue: 1
Pages: 79-91
Publication
First Author: Tavora B
Year: 2014
Journal: Nature
Title: Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy.
Volume: 514
Issue: 7520
Pages: 112-6
Publication
First Author: Tavora B
Year: 2010
Journal: EMBO Mol Med
Title: Endothelial FAK is required for tumour angiogenesis.
Volume: 2
Issue: 12
Pages: 516-28
Publication    
First Author: Rudnicki M
Year: 2018
Journal: Elife
Title: Endothelial-specific FoxO1 depletion prevents obesity-related disorders by increasing vascular metabolism and growth.
Volume: 7
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ccm2/Ccm2 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Benedito R
Year: 2012
Journal: Nature
Title: Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling.
Volume: 484
Issue: 7392
Pages: 110-4
Publication
First Author: Sabine A
Year: 2012
Journal: Dev Cell
Title: Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation.
Volume: 22
Issue: 2
Pages: 430-45
Publication
First Author: Nakayama M
Year: 2013
Journal: Nat Cell Biol
Title: Spatial regulation of VEGF receptor endocytosis in angiogenesis.
Volume: 15
Issue: 3
Pages: 249-60
Publication  
First Author: Shah AV
Year: 2017
Journal: Nat Commun
Title: The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability.
Volume: 8
Pages: 16002
Publication
First Author: Korhonen EA
Year: 2016
Journal: J Clin Invest
Title: Tie1 controls angiopoietin function in vascular remodeling and inflammation.
Volume: 126
Issue: 9
Pages: 3495-510
Publication
First Author: Izumi N
Year: 2012
Journal: PLoS One
Title: Fbxw7 controls angiogenesis by regulating endothelial Notch activity.
Volume: 7
Issue: 7
Pages: e41116
Publication
First Author: De Bock K
Year: 2013
Journal: Cell
Title: Role of PFKFB3-driven glycolysis in vessel sprouting.
Volume: 154
Issue: 3
Pages: 651-63
Publication    
First Author: Carvalho JR
Year: 2019
Journal: Elife
Title: Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration.
Volume: 8
Publication
First Author: Vandekeere S
Year: 2018
Journal: Cell Metab
Title: Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells.
Volume: 28
Issue: 4
Pages: 573-587.e13
Publication
First Author: Angulo-Urarte A
Year: 2018
Journal: Nat Commun
Title: Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility.
Volume: 9
Issue: 1
Pages: 4826
Publication
First Author: Poulsen LC
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Inhibition of Endothelial NOTCH1 Signaling Attenuates Inflammation by Reducing Cytokine-Mediated Histone Acetylation at Inflammatory Enhancers.
Volume: 38
Issue: 4
Pages: 854-869
Publication
First Author: Chapouly C
Year: 2016
Journal: Cardiovasc Res
Title: Impaired Hedgehog signalling-induced endothelial dysfunction is sufficient to induce neuropathy: implication in diabetes.
Volume: 109
Issue: 2
Pages: 217-27
Publication
First Author: Sakabe M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: YAP/TAZ-CDC42 signaling regulates vascular tip cell migration.
Volume: 114
Issue: 41
Pages: 10918-10923
Publication  
First Author: Yokoyama M
Year: 2019
Journal: J Mol Cell Cardiol
Title: p53 plays a crucial role in endothelial dysfunction associated with hyperglycemia and ischemia.
Volume: 129
Pages: 105-117
Publication
First Author: Bernier-Latmani J
Year: 2015
Journal: J Clin Invest
Title: DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport.
Volume: 125
Issue: 12
Pages: 4572-86
Publication  
First Author: Franco CA
Year: 2016
Journal: Elife
Title: Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling.
Volume: 5
Pages: e07727
Publication
First Author: Franco CA
Year: 2013
Journal: Development
Title: SRF selectively controls tip cell invasive behavior in angiogenesis.
Volume: 140
Issue: 11
Pages: 2321-33
Publication
First Author: Mleynek TM
Year: 2014
Journal: Hum Mol Genet
Title: Lack of CCM1 induces hypersprouting and impairs response to flow.
Volume: 23
Issue: 23
Pages: 6223-34
Publication
First Author: Bentley K
Year: 2014
Journal: Nat Cell Biol
Title: The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis.
Volume: 16
Issue: 4
Pages: 309-21
Publication
First Author: Fantin A
Year: 2015
Journal: Cell Rep
Title: NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells.
Volume: 11
Issue: 10
Pages: 1577-90
Publication
First Author: D'Amico G
Year: 2010
Journal: PLoS One
Title: Endothelial-Rac1 is not required for tumor angiogenesis unless alphavbeta3-integrin is absent.
Volume: 5
Issue: 3
Pages: e9766
Publication  
First Author: Bromage DI
Year: 2019
Journal: J Mol Cell Cardiol
Title: Stromal cell-derived factor-1α signals via the endothelium to protect the heart against ischaemia-reperfusion injury.
Volume: 128
Pages: 187-197
Publication
First Author: Hakanpaa L
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Targeting β1-integrin inhibits vascular leakage in endotoxemia.
Volume: 115
Issue: 28
Pages: E6467-E6476
Publication
First Author: Vion AC
Year: 2018
Journal: J Cell Biol
Title: Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression.
Volume: 217
Issue: 5
Pages: 1651-1665
Publication
First Author: Fan J
Year: 2014
Journal: Development
Title: Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.
Volume: 141
Issue: 2
Pages: 448-59
Genotype
Symbol: Jag1/Jag1 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: 129S1/Sv * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pdcd10/Pdcd10 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/? Pdzrn3/Pdzrn3 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6NCrlj * CBA * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pfkfb3/Pfkfb3 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sdc2/Sdc2 Tg(Pdgfb-icre/ERT2)1Frut/?
Background: involves: C57BL/6J * C57BL/6N * CBA
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Kuhnert F
Year: 2010
Journal: Science
Title: Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124.
Volume: 330
Issue: 6006
Pages: 985-9
Publication    
First Author: Travisano SI
Year: 2019
Journal: Elife
Title: Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade.
Volume: 8
Publication    
First Author: Benz F
Year: 2019
Journal: Elife
Title: Low wnt/β-catenin signaling determines leaky vessels in the subfornical organ and affects water homeostasis in mice.
Volume: 8
Publication
First Author: Nedvetsky PI
Year: 2016
Journal: Development
Title: cAMP-dependent protein kinase A (PKA) regulates angiogenesis by modulating tip cell behavior in a Notch-independent manner.
Volume: 143
Issue: 19
Pages: 3582-3590
Publication
First Author: Mathivet T
Year: 2017
Journal: EMBO Mol Med
Title: Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth.
Volume: 9
Issue: 12
Pages: 1629-1645
Publication
First Author: Wang Y
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Interplay of the Norrin and Wnt7a/Wnt7b signaling systems in blood-brain barrier and blood-retina barrier development and maintenance.
Volume: 115
Issue: 50
Pages: E11827-E11836
Publication
First Author: Peghaire C
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Fzd7 (Frizzled-7) Expressed by Endothelial Cells Controls Blood Vessel Formation Through Wnt/β-Catenin Canonical Signaling.
Volume: 36
Issue: 12
Pages: 2369-2380
Publication
First Author: Zhang J
Year: 2020
Journal: Cell Metab
Title: Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization.
Volume: 31
Issue: 6
Pages: 1136-1153.e7
Publication
First Author: Bonney S
Year: 2016
Journal: J Neurosci
Title: Diverse Functions of Retinoic Acid in Brain Vascular Development.
Volume: 36
Issue: 29
Pages: 7786-801
Publication
First Author: Liebner S
Year: 2008
Journal: J Cell Biol
Title: Wnt/beta-catenin signaling controls development of the blood-brain barrier.
Volume: 183
Issue: 3
Pages: 409-17
Publication
First Author: Renault MA
Year: 2013
Journal: Circ Res
Title: Desert hedgehog promotes ischemia-induced angiogenesis by ensuring peripheral nerve survival.
Volume: 112
Issue: 5
Pages: 762-70
Publication
First Author: Lange C
Year: 2016
Journal: EMBO J
Title: Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis.
Volume: 35
Issue: 9
Pages: 924-41
Publication
First Author: Bharath LP
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial Cell Autophagy Maintains Shear Stress-Induced Nitric Oxide Generation via Glycolysis-Dependent Purinergic Signaling to Endothelial Nitric Oxide Synthase.
Volume: 37
Issue: 9
Pages: 1646-1656
Publication    
First Author: Hu X
Year: 2019
Journal: Elife
Title: GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients.
Volume: 8
Publication  
First Author: Serra H
Year: 2015
Journal: Nat Commun
Title: PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.
Volume: 6
Pages: 7935
Publication  
First Author: Sewduth RN
Year: 2014
Journal: Nat Commun
Title: The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling.
Volume: 5
Pages: 4832