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Search results 1 to 100 out of 131 for Pdgfd

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
80310 | PDGFD
Type: gene
Organism: human
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Gene
100492060 | pdgfd
Type: gene
Organism: frog, western clawed
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Gene
479460 | PDGFD
Type: gene
Organism: dog, domestic
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Gene
466765 | PDGFD
Type: gene
Organism: chimpanzee
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Gene
66018 | Pdgfd
Type: gene
Organism: rat
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Gene
525931 | PDGFD
Type: gene
Organism: cattle
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Gene
418978 | PDGFD
Type: gene
Organism: chicken
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Gene
100535718 | pdgfd
Type: gene
Organism: zebrafish
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Gene
704310 | PDGFD
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR027123 | PDGFD
Type: Family
Description: Platelet-derived growth factor (PDGF) belongs to the PDGF/VEGF growth factor family, which are major mitogens for many types of cells and play an important role in angiogenesis and wound healing []. There are four PDGF isoforms: PDGF-A, -B, -C, which form homodimers or heterodimers (PDGF-AA, -BB, -AB, -CC, and -DD).This entry presents PDGFD, which plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. PDGFD induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis [, ].
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Protein Coding Gene
MGI:1919035 | Pdgfd
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15271796 | J:94895
First Author: Uutela M
Year: 2004
Journal: Blood
Title: PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis.
Volume: 104
Issue: 10
Pages: 3198-204
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Publication
11331881 | J:133559
First Author: Bergsten E
Year: 2001
Journal: Nat Cell Biol
Title: PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor.
Volume: 3
Issue: 5
Pages: 512-6
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Gene
105369464 | PDGFDDN
Type: gene
Organism: human
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Publication
36792607 | J:336289
First Author: Kim HJ
Year: 2023
Journal: Nat Commun
Title: Molecular mechanisms of coronary artery disease risk at the PDGFD locus.
Volume: 14
Issue: 1
Pages: 847
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Publication
18055825 | -
First Author: Li R
Year: 2007
Journal: Invest Ophthalmol Vis Sci
Title: PDGF-C and -D induced proliferation/migration of human RPE is abolished by inflammatory cytokines.
Volume: 48
Issue: 12
Pages: 5722-32
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GXD Expression
GXD Expression
     
Probe: MGI:6180340
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191059
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pdgfd
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6180340
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6191059
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pdgfd
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6180340
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6191059
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pdgfd
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6180340
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6191059
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pdgfd
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6180340
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191059
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pdgfd
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6180340
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191059
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pdgfd
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6180340
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191059
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pdgfd
Detected: true
Specimen Num: 7
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Protein
Q925I7
Organism: Mus musculus/domesticus
Length: 370  
Fragment?: false
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Publication
27032083 | J:249014
First Author: Gladh H
Year: 2016
Journal: PLoS One
Title: Mice Lacking Platelet-Derived Growth Factor D Display a Mild Vascular Phenotype.
Volume: 11
Issue: 3
Pages: e0152276
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Publication
25391964 | J:217538
First Author: Lui JH
Year: 2014
Journal: Nature
Title: Radial glia require PDGFD-PDGFRβ signalling in human but not mouse neocortex.
Volume: 515
Issue: 7526
Pages: 264-8
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Protein Coding Gene
MGP_CAROLIEiJ_G0031746 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034315 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034292 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034222 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034286 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033998 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1919035 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034808 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033325 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033970 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034127 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034072 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034214 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034116 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034827 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033029 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033441 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014625 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032866 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
11331882 | J:75185
First Author: LaRochelle WJ
Year: 2001
Journal: Nat Cell Biol
Title: PDGF-D, a new protease-activated growth factor.
Volume: 3
Issue: 5
Pages: 517-21
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Publication
12890490 | J:84792
First Author: Zhuo Y
Year: 2003
Journal: Biochem Biophys Res Commun
Title: A novel murine PDGF-D splicing variant results in significant differences in peptide expression and function.
Volume: 308
Issue: 1
Pages: 126-32
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Publication
26924050 | J:325432
First Author: Buhl EM
Year: 2016
Journal: Kidney Int
Title: The role of PDGF-D in healthy and fibrotic kidneys.
Volume: 89
Issue: 4
Pages: 848-61
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Publication
19028801 | J:146330
First Author: Thomas JA
Year: 2009
Journal: Am J Physiol Heart Circ Physiol
Title: PDGF-DD, a novel mediator of smooth muscle cell phenotypic modulation, is upregulated in endothelial cells exposed to atherosclerosis-prone flow patterns.
Volume: 296
Issue: 2
Pages: H442-52
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Publication
25332166 | J:223577
First Author: Hye Kim J
Year: 2015
Journal: Stem Cells
Title: Functional regulation of adipose-derived stem cells by PDGF-D.
Volume: 33
Issue: 2
Pages: 542-56
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GXD Expression
GXD Expression
   
Probe: MGI:4416013
Assay Type: RNA in situ
Annotation Date: 2023-11-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270423
Stage: TS23
Assay Id: MGI:7548652
Age: embryonic day 15.5
Note: No expression in any cell type.
Specimen Label: 3d inset 2
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4416013
Assay Type: RNA in situ
Annotation Date: 2023-11-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284223
Stage: TS23
Assay Id: MGI:7548652
Age: embryonic day 15.5
Specimen Label: 3d
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4416013
Assay Type: RNA in situ
Annotation Date: 2023-11-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:7548652
Age: embryonic day 14.5
Specimen Label: ED7b
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11241
Specimen Label: GUDMAP:11241
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11276
Specimen Label: GUDMAP:11276
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2853323
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11241
Specimen Label: GUDMAP:11241
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11241
Specimen Label: GUDMAP:11241
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11276
Specimen Label: GUDMAP:11276
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11241
Specimen Label: GUDMAP:11241
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11276
Specimen Label: GUDMAP:11276
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1869223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11241
Specimen Label: GUDMAP:11241
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2854023
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11276
Specimen Label: GUDMAP:11276
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11241
Specimen Label: GUDMAP:11241
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11276
Specimen Label: GUDMAP:11276
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11241
Specimen Label: GUDMAP:11241
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11241
Specimen Label: GUDMAP:11241
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11276
Specimen Label: GUDMAP:11276
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4416013
Assay Type: RNA in situ
Annotation Date: 2023-11-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754723
Stage: TS23
Assay Id: MGI:7548652
Age: embryonic day 15.5
Note: No expression in any cell type.
Specimen Label: 3d inset 2
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11241
Specimen Label: GUDMAP:11241
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11276
Specimen Label: GUDMAP:11276
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11241
Specimen Label: GUDMAP:11241
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11276
Specimen Label: GUDMAP:11276
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11241
Specimen Label: GUDMAP:11241
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11276
Specimen Label: GUDMAP:11276
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11276
Specimen Label: GUDMAP:11276
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11241
Specimen Label: GUDMAP:11241
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11276
Specimen Label: GUDMAP:11276
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:5002176
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5542730
Age: embryonic day 15.5
Image: GUDMAP:11276
Specimen Label: GUDMAP:11276
Detected: false
Specimen Num: 2
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Publication
34236404 | J:321635
 
First Author: Cheng YW
Year: 2021
Journal: J Exp Med
Title: PDGF-D activation by macrophage-derived uPA promotes AngII-induced cardiac remodeling in obese mice.
Volume: 218
Issue: 9
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Publication
29794241 | J:264040
First Author: Zhang ZB
Year: 2018
Journal: Diabetes
Title: Perivascular Adipose Tissue-Derived PDGF-D Contributes to Aortic Aneurysm Formation During Obesity.
Volume: 67
Issue: 8
Pages: 1549-1560
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