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Search results 1 to 100 out of 2787 for Pdgfra

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Type Details Score
Gene
5156 | PDGFRA
Type: gene
Organism: human
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Gene
461318 | PDGFRA
Type: gene
Organism: chimpanzee
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Gene
282301 | PDGFRA
Type: gene
Organism: cattle
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Gene
395509 | PDGFRA
Type: gene
Organism: chicken
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Gene
386856 | pdgfra
Type: gene
Organism: zebrafish
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Gene
697002 | PDGFRA
Type: gene
Organism: macaque, rhesus
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Gene
100124862 | pdgfra
Type: gene
Organism: frog, western clawed
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Gene
key_19524 | PDGFRA
Type: gene
Organism: pig, domestic
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Gene
key_36457 | PDGFRA
Type: gene
Organism: sheep
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Gene
25267 | Pdgfra
Type: gene
Organism: rat
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Gene
442860 | PDGFRA
Type: gene
Organism: dog, domestic
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Protein Domain
IPR027290 | PDGFRA
Type: Family
Description: Platelet-derived growth factor (PDGF) is a growth factor that plays a significant role in cell proliferation and embryonic develpment. It is regulated through the platelet-derived growth factor receptor (PDGFR), a tyrosine kinase (RTK) []. There are two types of PDGFR: alpha and beta. This entry represents the alpha type PDGFR (PDGFRA). In human, there are four genes expressing PDGF chains: PDGF-A, B, C and D. They can form isoforms with each other, such as PDGF-AA, AB, BB, CC and DD [, ]. PDGF isoforms bind twodistinct receptors, PDGF-alpha and -beta, and this mechanism induces receptor autophosphorylation and activates signal transduction []. PDGFR alpha acts as a receptor for homodimeric PDGF-AA, PDGF-BB and PDGF-CC and for heterodimers formed by PDGF-AB [, ]. The activities of the PDGFs have been extensively studied at the molecular and cellular level and in in vivo model systems [, , , , , , , , , ]. A chromosomal aberration involving PDGFRA is found in some cases of hypereosinophilic syndrome [, ]. Defects in PDGFRA are a cause of gastrointestinal stromal tumor [, ].
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Protein Coding Gene
MGI:97530 | Pdgfra
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:6196519
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6403333
Age: embryonic day 10.5-10.75
Image: 2B PDGFRa
Note: High levels of expression in core mesenchyme; lower levels in peripheral mesenchyme.
Specimen Label: 2B PDGFRa
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:2668508
Assay Type: RNA in situ
Annotation Date: 2018-02-21
Strength: Strong
Sex: Male
Emaps: EMAPS:1797220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6117304
Age: embryonic day 12.5
Image: 6 PDGFRa -/-
Note: Increased expression domain in region where the coelomic blood vessel is forming in mutant compared with wild-type.
Specimen Label: 6 PDGFRa -/-
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3718595
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6725809
Age: embryonic day 15.5
Image: S6A -/- PDGFRa
Specimen Label: S6A -/- PDGFRa
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3718595
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6725809
Age: embryonic day 15.5
Image: S6A R/- PDGFRa
Specimen Label: S6A R/- PDGFRa
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3718595
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6725809
Age: embryonic day 15.5
Image: S6A R/R PDGFRa
Specimen Label: S6A R/R PDGFRa
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3718595
Assay Type: Immunohistochemistry
Annotation Date: 2021-07-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:6725809
Age: embryonic day 15.5
Image: S6A R/+ PDGFRa
Specimen Label: S6A R/+ PDGFRa
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6196519
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752321
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7398225
Age: embryonic day 13.0-13.5
Image: 2C Pdgfra +/+
Note: Expression in capsular region.
Specimen Label: 2C Pdgfra +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6196519
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752321
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7398225
Age: embryonic day 13.0-13.5
Image: 2C Pdgfra +/neo2
Note: Expression in capsular region.
Specimen Label: 2C Pdgfra +/neo2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6196519
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752321
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7398225
Age: embryonic day 13.0-13.5
Image: 2C Pdgfra neo2/neo2 e.g.1
Note: Expression in capsular region.
Specimen Label: 2C Pdgfra neo2/neo2 e.g.1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6196519
Assay Type: Immunohistochemistry
Annotation Date: 2022-12-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752321
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7398225
Age: embryonic day 13.0-13.5
Image: 2C Pdgfra neo2/neo2 e.g.2
Note: Expression in capsular region.
Specimen Label: 2C Pdgfra neo2/neo2 e.g.2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6196519
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6403333
Age: embryonic day 10.5-10.75
Image: S2 PDGFRa E10.5-E10.75
Note: High levels of expression in core mesenchyme; lower levels in peripheral mesenchyme.
Specimen Label: S2 PDGFRa E10.5-E10.75
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6196519
Assay Type: Immunohistochemistry
Annotation Date: 2020-04-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6403333
Age: embryonic day 11.5
Image: S2 PDGFRa E11.5
Specimen Label: S2 PDGFRa E11.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:2668508
Assay Type: RNA in situ
Annotation Date: 2018-02-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6117304
Age: embryonic day 12.5
Image: 6 PDGFRa (right pane)
Specimen Label: 6 PDGFRa (right pane)
Detected: true
Specimen Num: 2
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Publication
12522257 | -
First Author: Heinrich MC
Year: 2003
Journal: Science
Title: PDGFRA activating mutations in gastrointestinal stromal tumors.
Volume: 299
Issue: 5607
Pages: 708-10
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Publication
15928335 | -
First Author: Corless CL
Year: 2005
Journal: J Clin Oncol
Title: PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib.
Volume: 23
Issue: 23
Pages: 5357-64
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Publication
20972453 | -
First Author: von Bubnoff N
Year: 2011
Journal: Oncogene
Title: The low frequency of clinical resistance to PDGFR inhibitors in myeloid neoplasms with abnormalities of PDGFRA might be related to the limited repertoire of possible PDGFRA kinase domain mutations in vitro.
Volume: 30
Issue: 8
Pages: 933-43
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Publication
33259802 | J:299739
First Author: Chen CCL
Year: 2020
Journal: Cell
Title: Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis.
Volume: 183
Issue: 6
Pages: 1617-1633.e22
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Publication
8586421 | -
First Author: Kawagishi J
Year: 1995
Journal: Genomics
Title: Structure, organization, and transcription units of the human alpha-platelet-derived growth factor receptor gene, PDGFRA.
Volume: 30
Issue: 2
Pages: 224-32
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Publication
12808148 | -
First Author: Griffin JH
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome.
Volume: 100
Issue: 13
Pages: 7830-5
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Publication
26971580 | J:232406
First Author: McCarthy N
Year: 2016
Journal: Dev Dyn
Title: Pdgfra and Pdgfrb genetically interact during craniofacial development.
Volume: 245
Issue: 6
Pages: 641-52
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Publication
36606407 | J:335804
First Author: Umar M
Year: 2023
Journal: Dev Dyn
Title: Characterizing the role of Pdgfra in calvarial development.
Volume: 252
Issue: 5
Pages: 589-604
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Publication
11331882 | J:75185
First Author: LaRochelle WJ
Year: 2001
Journal: Nat Cell Biol
Title: PDGF-D, a new protease-activated growth factor.
Volume: 3
Issue: 5
Pages: 517-21
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Publication
11331881 | J:133559
First Author: Bergsten E
Year: 2001
Journal: Nat Cell Biol
Title: PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor.
Volume: 3
Issue: 5
Pages: 512-6
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Publication
1653029 | -
First Author: Kazlauskas A
Year: 1991
Journal: Cell Regul
Title: Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit.
Volume: 2
Issue: 6
Pages: 413-25
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Publication
1709159 | -
First Author: Kelly JD
Year: 1991
Journal: J Biol Chem
Title: Platelet-derived growth factor (PDGF) stimulates PDGF receptor subunit dimerization and intersubunit trans-phosphorylation.
Volume: 266
Issue: 14
Pages: 8987-92
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Publication
9285559 | -
First Author: Chi KD
Year: 1997
Journal: Oncogene
Title: Integration of proviral DNA into the PDGF beta-receptor gene in HTLV-I-infected T-cells results in a novel tyrosine kinase product with transforming activity.
Volume: 15
Issue: 9
Pages: 1051-7
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Publication
2550144 | -
First Author: Kazlauskas A
Year: 1989
Journal: Cell
Title: Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins.
Volume: 58
Issue: 6
Pages: 1121-33
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Publication
2554309 | -
First Author: Matsui T
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Independent expression of human alpha or beta platelet-derived growth factor receptor cDNAs in a naive hematopoietic cell leads to functional coupling with mitogenic and chemotactic signaling pathways.
Volume: 86
Issue: 21
Pages: 8314-8
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Publication
1846866 | -
First Author: Sorkin A
Year: 1991
Journal: J Cell Biol
Title: Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor.
Volume: 112
Issue: 3
Pages: 469-78
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Publication
1314164 | -
First Author: Kashishian A
Year: 1992
Journal: EMBO J
Title: Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo.
Volume: 11
Issue: 4
Pages: 1373-82
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Publication
1396585 | -
First Author: Rönnstrand L
Year: 1992
Journal: EMBO J
Title: Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma.
Volume: 11
Issue: 11
Pages: 3911-9
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Publication
1313434 | -
First Author: Mori S
Year: 1992
Journal: J Biol Chem
Title: Ligand-induced polyubiquitination of the platelet-derived growth factor beta-receptor.
Volume: 267
Issue: 9
Pages: 6429-34
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Publication
17656670 | J:134892
First Author: Magnusson PU
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Platelet-derived growth factor receptor-beta constitutive activity promotes angiogenesis in vivo and in vitro.
Volume: 27
Issue: 10
Pages: 2142-9
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DO Term
DOID:0080165 | myeloid and lymphoid neoplasms associated with PDGFRA rearrangement
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Publication
21938754 | -
First Author: Chmielecki J
Year: 2012
Journal: Genes Chromosomes Cancer
Title: Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm.
Volume: 51
Issue: 1
Pages: 54-65
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Publication
10036976 | J:52810
First Author: Stephenson DA
Year: 1998
Journal: Genet Res
Title: Analysis of the Kit and Pdgfra genes in the patch-extended (Phe) mutation.
Volume: 72
Issue: 3
Pages: 205-10
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Protein
P26618
Organism: Mus musculus/domesticus
Length: 1089  
Fragment?: false
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Publication
9510033 | J:46139
First Author: Zhang XQ
Year: 1998
Journal: Mech Dev
Title: Specific expression in mouse mesoderm- and neural crest-derived tissues of a human PDGFRA promoter/lacZ transgene.
Volume: 70
Issue: 1-2
Pages: 167-80
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Publication
28919262 | J:279991
First Author: Lin J
Year: 2017
Journal: Stem Cell Reports
Title: PDGFRA Is Not Essential for the Derivation and Maintenance of Mouse Extraembryonic Endoderm Stem Cell Lines.
Volume: 9
Issue: 4
Pages: 1062-1070
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Publication
33001865 | J:301925
 
First Author: Song K
Year: 2020
Journal: JCI Insight
Title: PDGFRA in vascular adventitial MSCs promotes neointima formation in arteriovenous fistula in chronic kidney disease.
Volume: 5
Issue: 21
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Publication
32800757 | J:296399
First Author: Bartoletti G
Year: 2020
Journal: Dev Biol
Title: Pdgfra regulates multipotent cell differentiation towards chondrocytes via inhibiting Wnt9a/beta-catenin pathway during chondrocranial cartilage development.
Volume: 466
Issue: 1-2
Pages: 36-46
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Publication
29107533 | J:249297
First Author: Pathania M
Year: 2017
Journal: Cancer Cell
Title: H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas.
Volume: 32
Issue: 5
Pages: 684-700.e9
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Publication
24449836 | J:208340
First Author: Zhu Q
Year: 2014
Journal: Development
Title: Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS.
Volume: 141
Issue: 3
Pages: 548-55
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Publication
28379539 | J:246173
First Author: Garon G
Year: 2017
Journal: Endocrinology
Title: FOXA3 Is Expressed in Multiple Cell Lineages in the Mouse Testis and Regulates Pdgfra Expression in Leydig Cells.
Volume: 158
Issue: 6
Pages: 1886-1897
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Publication
20071345 | J:157946
First Author: Bleyl SB
Year: 2010
Journal: Hum Mol Genet
Title: Dysregulation of the PDGFRA gene causes inflow tract anomalies including TAPVR: integrating evidence from human genetics and model organisms.
Volume: 19
Issue: 7
Pages: 1286-301
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GXD Expression
GXD Expression
Probe: MGI:6180341
Assay Type: RNA in situ
Annotation Date: 2020-09-23
Strength: Present
Sex: Male
Emaps: EMAPS:1754426
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6456799
Age: embryonic day 18.5
Image: S13
Note: Pdgfra is an oligodendrocyte marker.
Specimen Label: S13
Detected: true
Specimen Num: 1
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Publication
11544480 | J:86390
First Author: MacDonald TJ
Year: 2001
Journal: Nat Genet
Title: Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease.
Volume: 29
Issue: 2
Pages: 143-52
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GXD Expression
GXD Expression
   
Probe: MGI:6180341
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191060
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pdgfra
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6180341
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191060
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pdgfra
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6180341
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191060
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pdgfra
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6180341
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191060
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pdgfra
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6180341
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191060
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pdgfra
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6180341
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191060
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pdgfra
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6180341
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191060
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pdgfra
Detected: true
Specimen Num: 6
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Protein
Q8CGH8
Organism: Mus musculus/domesticus
Length: 486  
Fragment?: true
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GXD Expression
GXD Expression
Probe: MGI:6196519
Assay Type: Immunohistochemistry
Annotation Date: 2022-06-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7281560
Age: postnatal month 1
Image: 3D
Note: Pdgfra labeled cells increased 40.5% in the conditional mutant corpus callosum compared to control.
Specimen Label: 3D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6295967
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116916
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:6295974
Age: embryonic day 10.0
Note: At E10.0, Splotch embryos displayed normal spatial localization of Pdgfra transcripts.
Specimen Label: 2h Splotch
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6295967
Assay Type: RNA in situ
Annotation Date: 2019-05-06
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3116920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6295974
Age: embryonic day 12.5
Note: By E12.5, Pdgfra expression was severely decreased in the thoracic somite region and ventrally truncated.
Specimen Label: 2i Splotch
Detected: true
Specimen Num: 4
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Publication
33224039 | J:302565
 
First Author: Mo J
Year: 2020
Journal: Front Physiol
Title: Pdgfra and Pdgfrb Genetically Interact in the Murine Neural Crest Cell Lineage to Regulate Migration and Proliferation.
Volume: 11
Pages: 588901
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Publication
30178747 | J:281590
   
First Author: Li R
Year: 2018
Journal: Elife
Title: Pdgfra marks a cellular lineage with distinct contributions to myofibroblasts in lung maturation and injury response.
Volume: 7
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Publication
23970477 | J:202759
First Author: Paugh BS
Year: 2013
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First Author: Smith EA
Year: 1991
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First Author: Payne J
Year: 1997
Journal: Dev Dyn
Title: Spina bifida occulta in homozygous Patch mouse embryos.
Volume: 209
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Pages: 105-16
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1322271 | J:1104
First Author: Orr-Urtreger A
Year: 1992
Journal: Development
Title: Developmental expression of the alpha receptor for platelet-derived growth factor, which is deleted in the embryonic lethal Patch mutation.
Volume: 115
Issue: 1
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First Author: Stephenson DA
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation.
Volume: 88
Issue: 1
Pages: 6-10
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First Author: Ogura Y
Year: 1998
Journal: Biol Reprod
Title: Essential role of platelet-derived growth factor receptor alpha in the development of the intraplacental yolk sac/sinus of Duval in mouse placenta.
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Pages: 65-72
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First Author: Morrison-Graham K
Year: 1992
Journal: Development
Title: A PDGF receptor mutation in the mouse (Patch) perturbs the development of a non-neuronal subset of neural crest-derived cells.
Volume: 115
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First Author: Schatteman GC
Year: 1992
Journal: Development
Title: Regulation and role of PDGF receptor alpha-subunit expression during embryogenesis.
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First Author: Li L
Year: 1996
Journal: Brain Res Dev Brain Res
Title: Altered development of spinal cord in the mouse mutant (Patch) lacking the PDGF receptor alpha-subunit gene.
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First Author: Truslove GM
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First Author: Đặng TC
Year: 2019
Journal: Cell Rep
Title: Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFRα in Adult Brain.
Volume: 27
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First Author: Loutit JF
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Journal: Genet Res
Title: Haematopoietic role for Patch (Ph) revealed by new W mutant (Wct) in mice.
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First Author: Schatteman GC
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Journal: Teratology
Title: Platelet-derived growth factor receptor alpha subunit deleted Patch mouse exhibits severe cardiovascular dysmorphogenesis.
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First Author: Sun T
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Title: A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth.
Volume: 127
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Title: A 1.8-Mb YAC contig spanning three members of the receptor tyrosine kinase gene family (Pdgfra, Kit, and Flk1) on mouse chromosome 5.
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Journal: Nat Commun
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Title: Mesoderm-derived PDGFRA(+) cells regulate the emergence of hematopoietic stem cells in the dorsal aorta.
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