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Search results 1 to 100 out of 3383 for Pdx1

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Hits by Strain

Type Details Score
Gene
key_980053 | Pdx1
Type: gene
Organism: Not Specified
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Gene
3651 | PDX1
Type: gene
Organism: human
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Gene
100490648 | pdx1
Type: gene
Organism: frog, western clawed
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Gene
29535 | Pdx1
Type: gene
Organism: rat
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Gene
493994 | PDX1
Type: gene
Organism: dog, domestic
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Gene
452507 | PDX1
Type: gene
Organism: chimpanzee
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Gene
538927 | PDX1
Type: gene
Organism: cattle
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Gene
771348 | PDX1
Type: gene
Organism: chicken
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Gene
30721 | pdx1
Type: gene
Organism: zebrafish
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Gene
710936 | PDX1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:102851 | Pdx1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:3820908
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3565022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826040
Age: embryonic day 14.5
Image: Additional file 4 Pdx1
Specimen Label: Additional file 4 Pdx1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:8166915
Assay Type: Immunohistochemistry
Annotation Date: 2025-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8166941
Age: postnatal week 8
Image: 3B CTRL Pdx1
Specimen Label: 3B CTRL Pdx1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:8166915
Assay Type: Immunohistochemistry
Annotation Date: 2025-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8166941
Age: postnatal week 8
Image: 3B M15beta Pdx1
Specimen Label: 3B M15beta Pdx1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:8166915
Assay Type: Immunohistochemistry
Annotation Date: 2025-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:8166941
Age: postnatal day 1
Image: S4A P1 M15beta Pdx1
Specimen Label: S4A P1 M15beta Pdx1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:8166915
Assay Type: Immunohistochemistry
Annotation Date: 2025-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8166941
Age: postnatal day 7
Image: S4A P7 CTRL Pdx1
Specimen Label: S4A P7 CTRL Pdx1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:8166915
Assay Type: Immunohistochemistry
Annotation Date: 2025-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8166941
Age: postnatal day 14
Image: S4A P14 CTRL Pdx1
Specimen Label: S4A P14 CTRL Pdx1
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:8166915
Assay Type: Immunohistochemistry
Annotation Date: 2025-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8166941
Age: postnatal day 14
Image: S4A P14 M15beta Pdx1
Specimen Label: S4A P14 M15beta Pdx1
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:8166915
Assay Type: Immunohistochemistry
Annotation Date: 2025-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8166941
Age: postnatal week 3
Image: S4A 3wk M15beta Pdx1
Specimen Label: S4A 3wk M15beta Pdx1
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:8166915
Assay Type: Immunohistochemistry
Annotation Date: 2025-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8166941
Age: postnatal week 4
Image: S4A 4wk CTRL Pdx1
Specimen Label: S4A 4wk CTRL Pdx1
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:8166915
Assay Type: Immunohistochemistry
Annotation Date: 2025-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:8166941
Age: postnatal day 1
Image: S4A P1 CTRL Pdx1
Specimen Label: S4A P1 CTRL Pdx1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:8166915
Assay Type: Immunohistochemistry
Annotation Date: 2025-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8166941
Age: postnatal day 7
Image: S4A P7 M15beta Pdx1
Specimen Label: S4A P7 M15beta Pdx1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:8166915
Assay Type: Immunohistochemistry
Annotation Date: 2025-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8166941
Age: postnatal week 3
Image: S4A 3wk CTRL Pdx1
Specimen Label: S4A 3wk CTRL Pdx1
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:8166915
Assay Type: Immunohistochemistry
Annotation Date: 2025-04-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:8166941
Age: postnatal week 4
Image: S4A 4wk M15beta Pdx1
Specimen Label: S4A 4wk M15beta Pdx1
Detected: true
Specimen Num: 12
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Gene
100861550 | PLUT
Type: gene
Organism: human
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Publication
26657766 | J:229014
First Author: Marty-Santos L
Year: 2016
Journal: Development
Title: Pdx1 regulates pancreas tubulogenesis and E-cadherin expression.
Volume: 143
Issue: 1
Pages: 101-12
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Publication
21852533 | J:174673
First Author: Yang YP
Year: 2011
Journal: Genes Dev
Title: Context-specific ?- to-?-cell reprogramming by forced Pdx1 expression.
Volume: 25
Issue: 16
Pages: 1680-5
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Publication
28017717 | J:241963
First Author: Yamamoto Y
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Preserving expression of Pdx1 improves ?-cell failure in diabetic mice.
Volume: 483
Issue: 1
Pages: 418-424
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GXD Expression
GXD Expression
   
Probe: MGI:7492310
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7492350
Age: embryonic day 15.5
Specimen Label: S1 PDX1 E15.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7492310
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7492350
Age: embryonic day 10.5
Specimen Label: S1 PDX1 E10.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7492310
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7492350
Age: embryonic day 11.5
Specimen Label: S1 PDX1 E11.5
Detected: true
Specimen Num: 2
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Publication
28087712 | J:238701
First Author: Roy N
Year: 2016
Journal: Genes Dev
Title: PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance.
Volume: 30
Issue: 24
Pages: 2669-2683
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Publication
26887806 | J:250031
 
First Author: Kodama S
Year: 2016
Journal: Sci Rep
Title: Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice.
Volume: 6
Pages: 21211
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Publication
12145169 | J:78086
First Author: Lee CS
Year: 2002
Journal: Diabetes
Title: Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo.
Volume: 51
Issue: 8
Pages: 2546-51
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Publication
11994408 | J:76408
First Author: Kushner JA
Year: 2002
Journal: J Clin Invest
Title: Pdx1 restores beta cell function in Irs2 knockout mice.
Volume: 109
Issue: 9
Pages: 1193-201
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Publication
38171340 | J:388984
First Author: Weidemann BJ
Year: 2024
Journal: Cell Metab
Title: Repression of latent NF-??B enhancers by PDX1 regulates ?? cell functional heterogeneity.
Volume: 36
Issue: 1
Pages: 90-102.e7
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Publication
28580283 | J:301635
First Author: Bastidas-Ponce A
Year: 2017
Journal: Mol Metab
Title: Foxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic ?-cells.
Volume: 6
Issue: 6
Pages: 524-534
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Publication
20558340 | J:161931
First Author: Galbo T
Year: 2010
Journal: Eur J Histochem
Title: Novel monoclonal antibodies against Pdx1 reveal feedback regulation of Pdx1 protein levels.
Volume: 54
Issue: 2
Pages: e19
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Publication
19855005 | J:154661
First Author: Sachdeva MM
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress.
Volume: 106
Issue: 45
Pages: 19090-5
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Publication
29351489 | J:262148
First Author: Kropp PA
Year: 2018
Journal: Am J Physiol Endocrinol Metab
Title: Cooperative function of Pdx1 and Oc1 in multipotent pancreatic progenitors impacts postnatal islet maturation and adaptability.
Volume: 314
Issue: 4
Pages: E308-E321
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Publication
19656489 | J:151308
First Author: Gauthier BR
Year: 2009
Journal: Cell Metab
Title: PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression.
Volume: 10
Issue: 2
Pages: 110-8
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Publication
17403901 | J:122333
First Author: Wiebe PO
Year: 2007
Journal: Mol Cell Biol
Title: Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression.
Volume: 27
Issue: 11
Pages: 4093-104
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Publication
24658302 | J:229796
First Author: Ren D
Year: 2014
Journal: Diabetes
Title: Role of BH3-only molecules Bim and Puma in ?-cell death in Pdx1 deficiency.
Volume: 63
Issue: 8
Pages: 2744-50
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Publication
41528843 | J:382935
First Author: Fan J
Year: 2026
Journal: Cell Rep
Title: PDX1 phosphorylation at S61 by mTORC1 links nutrient signaling to ? cell function and metabolic disease.
Volume: 45
Issue: 1
Pages: 116811
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Publication
24506867 | J:210652
First Author: Gao T
Year: 2014
Journal: Cell Metab
Title: Pdx1 maintains ? cell identity and function by repressing an ? cell program.
Volume: 19
Issue: 2
Pages: 259-71
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Publication
27292642 | J:238301
First Author: Henley KD
Year: 2016
Journal: Cell Rep
Title: Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and ?-Cell Function.
Volume: 15
Issue: 12
Pages: 2637-2650
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Publication
17158802 | J:118281
First Author: Johnson JD
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome.
Volume: 103
Issue: 51
Pages: 19575-80
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Publication
16126192 | J:103522
First Author: Hale MA
Year: 2005
Journal: Dev Biol
Title: The homeodomain protein PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas.
Volume: 286
Issue: 1
Pages: 225-37
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Publication
22135308 | J:183312
First Author: Chen C
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Expression profiling identifies novel gene targets and functions for Pdx1 in the duodenum of mature mice.
Volume: 302
Issue: 4
Pages: G407-19
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Publication
24029239 | J:204080
First Author: Nishimura W
Year: 2013
Journal: Endocrinology
Title: Quantitative assessment of Pdx1 promoter activity in vivo using a secreted luciferase reporter system.
Volume: 154
Issue: 11
Pages: 4388-95
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Publication
12488434 | J:80826
First Author: Kitamura T
Year: 2002
Journal: J Clin Invest
Title: The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth.
Volume: 110
Issue: 12
Pages: 1839-47
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Publication
25801033 | J:316508
First Author: McKenna B
Year: 2015
Journal: Cell Rep
Title: Dynamic recruitment of functionally distinct Swi/Snf chromatin remodeling complexes modulates Pdx1 activity in islet ? cells.
Volume: 10
Issue: 12
Pages: 2032-42
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Publication
15677506 | J:105152
First Author: Li Y
Year: 2005
Journal: Diabetes
Title: beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1.
Volume: 54
Issue: 2
Pages: 482-91
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Publication
26085571 | J:247099
First Author: Soleimanpour SA
Year: 2015
Journal: Diabetes
Title: Diabetes Susceptibility Genes Pdx1 and Clec16a Function in a Pathway Regulating Mitophagy in ?-Cells.
Volume: 64
Issue: 10
Pages: 3475-84
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Publication
33569632 | J:367916
First Author: Zhang M
Year: 2021
Journal: Diabetologia
Title: Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function.
Volume: 64
Issue: 5
Pages: 1144-1157
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Publication
29723041 | J:272409
First Author: Ikeguchi E
Year: 2018
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Transcriptional factor Pdx1 is involved in age-related GIP hypersecretion in mice.
Volume: 315
Issue: 2
Pages: G272-G282
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Publication
19654319 | J:155712
First Author: Fujimoto K
Year: 2009
Journal: J Biol Chem
Title: Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation.
Volume: 284
Issue: 40
Pages: 27664-73
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Publication
12869553 | J:128796
First Author: Suzuki R
Year: 2003
Journal: J Biol Chem
Title: Pdx1 expression in Irs2-deficient mouse beta-cells is regulated in a strain-dependent manner.
Volume: 278
Issue: 44
Pages: 43691-8
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Publication
25040025 | J:215612
First Author: Fern?ndez-P?rez A
Year: 2014
Journal: Biochem J
Title: Pdx1 and USF transcription factors co-ordinately regulate Alx3 gene expression in pancreatic ?-cells.
Volume: 463
Issue: 2
Pages: 287-96
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Publication
25251389 | J:218424
First Author: Templin AT
Year: 2014
Journal: Mol Endocrinol
Title: Maintenance of Pdx1 mRNA translation in islet ?-cells during the unfolded protein response.
Volume: 28
Issue: 11
Pages: 1820-30
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Publication
31240701 | J:280914
First Author: Horiguchi M
Year: 2019
Journal: FEBS Lett
Title: Senescence caused by inactivation of the homeodomain transcription factor Pdx1 in adult pancreatic acinar cells in mice.
Volume: 593
Issue: 16
Pages: 2226-2234
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Publication
22771330 | J:186237
First Author: Chen C
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Intestinal Pdx1 mediates nutrient metabolism gene networks and maternal expression is essential for perinatal growth in mice.
Volume: 424
Issue: 3
Pages: 549-53
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Publication
23775765 | J:208954
First Author: Guo L
Year: 2013
Journal: Diabetes
Title: PDX1 in ducts is not required for postnatal formation of ?-cells but is necessary for their subsequent maturation.
Volume: 62
Issue: 10
Pages: 3459-68
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Publication
20811152 | J:165268
First Author: Claiborn KC
Year: 2010
Journal: J Clin Invest
Title: Pcif1 modulates Pdx1 protein stability and pancreatic ? cell function and survival in mice.
Volume: 120
Issue: 10
Pages: 3713-21
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Publication
17056599 | J:117676
First Author: Deramaudt TB
Year: 2006
Journal: J Biol Chem
Title: The PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoter.
Volume: 281
Issue: 50
Pages: 38385-95
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Publication
21042537 | J:166709
First Author: Mazur PK
Year: 2010
Journal: PLoS One
Title: Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo.
Volume: 5
Issue: 10
Pages: e13578
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Publication
19141476 | J:143476
First Author: Gao N
Year: 2008
Journal: Genes Dev
Title: Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.
Volume: 22
Issue: 24
Pages: 3435-48
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Publication
19487809 | J:152582
First Author: Oliver-Krasinski JM
Year: 2009
Journal: J Clin Invest
Title: The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice.
Volume: 119
Issue: 7
Pages: 1888-98
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Publication
37081806 | J:359631
First Author: Walcheck MT
Year: 2023
Journal: Leuk Lymphoma
Title: Pdx1 expression in hematopoietic cells activates Kras-mutation to drive leukemia in KC (Pdx1-Cre; LSL-Kras(G12D/+)) mice.
Volume: 64
Issue: 6
Pages: 1112-1122
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Publication
29910119 | J:264987
 
First Author: Malenczyk K
Year: 2018
Journal: Mol Metab
Title: Secretagogin protects Pdx1 from proteasomal degradation to control a transcriptional program required for ? cell specification.
Volume: 14
Pages: 108-120
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Publication
27993987 | J:238418
First Author: Yang YP
Year: 2017
Journal: Development
Title: The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal ?-cell maturation.
Volume: 144
Issue: 2
Pages: 248-257
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Publication
16148004 | J:102900
First Author: Iguchi H
Year: 2005
Journal: J Biol Chem
Title: SOX6 attenuates glucose-stimulated insulin secretion by repressing PDX1 transcriptional activity and is down-regulated in hyperinsulinemic obese mice.
Volume: 280
Issue: 45
Pages: 37669-80
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Publication
25713082 | J:338772
First Author: Maganti AV
Year: 2015
Journal: J Biol Chem
Title: Transcriptional activity of the islet ? cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9.
Volume: 290
Issue: 15
Pages: 9812-22
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Publication
26440894 | J:273053
First Author: Shih HP
Year: 2015
Journal: Cell Rep
Title: A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells.
Volume: 13
Issue: 2
Pages: 326-36
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Publication
27406855 | J:253778
 
First Author: Guo C
Year: 2016
Journal: Sci Rep
Title: Chronic hyperglycemia induced via the heterozygous knockout of Pdx1 worsens neuropathological lesion in an Alzheimer mouse model.
Volume: 6
Pages: 29396
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Publication
16794995 | J:110137
First Author: Holland AM
Year: 2006
Journal: Genesis
Title: A mouse carrying the green fluorescent protein gene targeted to the Pdx1 locus facilitates the study of pancreas development and function.
Volume: 44
Issue: 6
Pages: 304-7
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Publication
16123346 | J:101742
First Author: Holland AM
Year: 2005
Journal: Diabetes
Title: Conditional expression demonstrates the role of the homeodomain transcription factor Pdx1 in maintenance and regeneration of beta-cells in the adult pancreas.
Volume: 54
Issue: 9
Pages: 2586-95
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Publication
16962573 | J:119565
First Author: Boyer DF
Year: 2006
Journal: Dev Biol
Title: Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression.
Volume: 298
Issue: 2
Pages: 616-31
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Publication
16418487 | J:104617
First Author: Fujitani Y
Year: 2006
Journal: Genes Dev
Title: Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.
Volume: 20
Issue: 2
Pages: 253-66
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Publication
28705881 | J:245178
First Author: Spaeth JM
Year: 2017
Journal: Diabetes
Title: Defining a Novel Role for the Pdx1 Transcription Factor in Islet ?-Cell Maturation and Proliferation During Weaning.
Volume: 66
Issue: 11
Pages: 2830-2839
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Publication
19808654 | J:155907
First Author: Chen C
Year: 2009
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Pdx1 inactivation restricted to the intestinal epithelium in mice alters duodenal gene expression in enterocytes and enteroendocrine cells.
Volume: 297
Issue: 6
Pages: G1126-37
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Publication
18347078 | J:137140
First Author: Hald J
Year: 2008
Journal: J Histochem Cytochem
Title: Generation and characterization of Ptf1a antiserum and localization of Ptf1a in relation to Nkx6.1 and Pdx1 during the earliest stages of mouse pancreas development.
Volume: 56
Issue: 6
Pages: 587-95
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Gene
771963 | PCIF1
Type: gene
Organism: chicken
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HT Experiment
E-MTAB-127 | Transcription profiling of the islets from Pdx1+/- mice compared to islets isolated from Pdx1 +/+ littermates
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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GXD Expression
GXD Expression
 
Probe: MGI:7852638
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564521
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7853925
Age: embryonic day 13.5
Note: A subset of Pdx1-positive cells co-express Cpa1, which represent 13.6% of total Pdx1 cells at E13.5.
Specimen Label: 3K
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7852638
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7853925
Age: embryonic day 14.5
Note: A subset of Pdx1-positive cells co-express Cpa1, which represent 16.8% of total Pdx1 cells at E14.5.
Specimen Label: 3L
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6361200
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6361315
Age: embryonic day 10.5
Image: S1G
Note: The antibody used recognized the truncated Pdx1 protein expressed in the Pdx1;Sox9 mutant allele.
Specimen Label: S1G
Detected: true
Specimen Num: 20
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GXD Expression
GXD Expression
Probe: MGI:6361200
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1654817
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6361315
Age: embryonic day 10.5
Image: 6G
Note: The antibody used recognized the truncated Pdx1 protein expressed in the Pdx1;Sox9 mutant allele.
Specimen Label: 6G
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:6361200
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1706717
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6361315
Age: embryonic day 10.5
Image: 6F
Note: The antibody used recognized the truncated Pdx1 protein expressed in the Pdx1 null allele.
Specimen Label: 6F
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:6361200
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706716
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:6361503
Age: embryonic day 9.5
Image: S3D
Note: The antibody used recognized the truncated Pdx1 protein expressed in the Pdx1 null allele.
Specimen Label: S3D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6361200
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702116
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:6361503
Age: embryonic day 9.5
Image: S3C
Note: The antibody used recognized the truncated Pdx1 protein expressed in the Pdx1 null allele.
Specimen Label: S3C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7852638
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7853925
Age: embryonic day 12.5
Note: A subset of Pdx1-positive cells co-express Cpa1, which represent 13.3% of total Pdx1 cells at E12.5.
Specimen Label: 3J
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6361200
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1706617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6361315
Age: embryonic day 10.5
Image: S1F
Note: The antibody used recognized the truncated Pdx1 protein expressed in the Pdx1 null allele.
Specimen Label: S1F
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750320
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6695725
Age: embryonic day 12.5
Image: 3E (left)
Note: Considerably smaller dorsal pancreatic remnant than Pdx1 null embryos at same stage, while displaying a similar structure.
Specimen Label: 3E (left)
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636317
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6361425
Age: embryonic day 10.5
Image: 3O
Note: With increasing loss of Sox9 dosage on the Pdx1 null background, dorsal and ventral pancreatic buds become increasingly hypoplastic and not discernable.
Specimen Label: 3O
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636317
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6361425
Age: embryonic day 10.5
Image: 3Q
Note: With increasing loss of Sox9 dosage on the Pdx1 null background, dorsal and ventral pancreatic buds become increasingly hypoplastic and not discernable.
Specimen Label: 3Q
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636317
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6361425
Age: embryonic day 10.5
Image: 3S
Note: With increasing loss of Sox9 dosage on the Pdx1 null background, dorsal and ventral pancreatic buds become increasingly hypoplastic and not discernable.
Specimen Label: 3S
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1636320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6361425
Age: embryonic day 12.5
Image: 3T
Note: With increasing loss of Sox9 dosage on the Pdx1 null background, dorsal and ventral pancreatic buds become increasingly hypoplastic and not discernable.
Specimen Label: 3T
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:6361200
Assay Type: Immunohistochemistry
Annotation Date: 2019-09-30
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1636317
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6361315
Age: embryonic day 10.5
Image: 6G
Note: Loss of both Pdx1 and Sox9 results in ectopic Cdx2 expression. There was extensive overlap between the Pdx1 and Cdx2 domains.
Specimen Label: 6G
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2019-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:6361425
Age: embryonic day 12.5
Image: 3P
Note: With increasing loss of Sox9 dosage on the Pdx1 null background, dorsal and ventral pancreatic buds become increasingly hypoplastic and not discernable.
Specimen Label: 3P
Detected: true
Specimen Num: 8
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