|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 2523 for Pdx1

<< First    < Previous  |  Next >    Last >>
0.045s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Roy N
Year: 2016
Journal: Genes Dev
Title: PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance.
Volume: 30
Issue: 24
Pages: 2669-2683
Publication
First Author: Yamamoto Y
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Preserving expression of Pdx1 improves β-cell failure in diabetic mice.
Volume: 483
Issue: 1
Pages: 418-424
Publication
First Author: Wiebe PO
Year: 2007
Journal: Mol Cell Biol
Title: Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression.
Volume: 27
Issue: 11
Pages: 4093-104
Publication
First Author: Kropp PA
Year: 2018
Journal: Am J Physiol Endocrinol Metab
Title: Cooperative function of Pdx1 and Oc1 in multipotent pancreatic progenitors impacts postnatal islet maturation and adaptability.
Volume: 314
Issue: 4
Pages: E308-E321
Publication
First Author: Henley KD
Year: 2016
Journal: Cell Rep
Title: Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.
Volume: 15
Issue: 12
Pages: 2637-2650
Publication
First Author: Mazur PK
Year: 2010
Journal: PLoS One
Title: Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo.
Volume: 5
Issue: 10
Pages: e13578
Publication
First Author: Gao N
Year: 2008
Journal: Genes Dev
Title: Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.
Volume: 22
Issue: 24
Pages: 3435-48
Publication
First Author: Yang YP
Year: 2017
Journal: Development
Title: The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.
Volume: 144
Issue: 2
Pages: 248-257
Publication
First Author: Shih HP
Year: 2015
Journal: Cell Rep
Title: A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells.
Volume: 13
Issue: 2
Pages: 326-36
Gene
Type: gene
Organism: Homo sapiens
GXD Expression  
Probe: MGI:3820908
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3565022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826040
Age: embryonic day 14.5
Image: Additional file 4 Pdx1
Detected: true
Specimen Num: 1
Publication
First Author: Gannon M
Year: 2001
Journal: Dev Biol
Title: Regulatory regions driving developmental and tissue-specific expression of the essential pancreatic gene pdx1.
Volume: 238
Issue: 1
Pages: 185-201
Publication
First Author: Trojanowski BM
Year: 2020
Journal: J Endocrinol
Title: Elevated β-cell stress levels promote severe diabetes development in mice with MODY4.
Volume: 244
Issue: 2
Pages: 323-337
Publication  
First Author: Baumann D
Year: 2020
Journal: Development
Title: Role of nutrient-driven O-GlcNAc-post-translational modification in pancreatic exocrine and endocrine islet development.
Volume: 147
Issue: 7
Publication
First Author: Heiser PW
Year: 2006
Journal: Development
Title: Stabilization of beta-catenin impacts pancreas growth.
Volume: 133
Issue: 10
Pages: 2023-32
Publication
First Author: Gu G
Year: 2002
Journal: Development
Title: Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.
Volume: 129
Issue: 10
Pages: 2447-57
Publication
First Author: Jiang FX
Year: 2017
Journal: Stem Cells Dev
Title: Transient Impairment of Islet Architectural Development in Pancreas-Specific Bmpr1a-Deleted Prenatal Mice Involves Reduced Expression of E-Cadherin.
Volume: 26
Issue: 23
Pages: 1706-1714
Publication
First Author: Iglesias J
Year: 2012
Journal: J Clin Invest
Title: PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice.
Volume: 122
Issue: 11
Pages: 4105-17
Publication
First Author: Wicksteed B
Year: 2010
Journal: Diabetes
Title: Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.
Volume: 59
Issue: 12
Pages: 3090-8
Publication
First Author: Spence JR
Year: 2009
Journal: Dev Cell
Title: Sox17 regulates organ lineage segregation of ventral foregut progenitor cells.
Volume: 17
Issue: 1
Pages: 62-74
Publication
First Author: Cai EP
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate.
Volume: 110
Issue: 36
Pages: 14723-8
Publication
First Author: Shen HC
Year: 2009
Journal: Cancer Res
Title: Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1.
Volume: 69
Issue: 5
Pages: 1858-66
Publication  
First Author: Honig G
Year: 2010
Journal: J Biomed Sci
Title: Precise pattern of recombination in serotonergic and hypothalamic neurons in a Pdx1-cre transgenic mouse line.
Volume: 17
Pages: 82
Publication
First Author: Valtat B
Year: 2011
Journal: Diabetologia
Title: Genetic evidence of the programming of beta cell mass and function by glucocorticoids in mice.
Volume: 54
Issue: 2
Pages: 350-9
Publication
First Author: Du A
Year: 2009
Journal: Diabetes
Title: Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.
Volume: 58
Issue: 9
Pages: 2059-69
Publication
First Author: Gupta D
Year: 2008
Journal: J Biol Chem
Title: In vivo and in vitro studies of a functional peroxisome proliferator-activated receptor gamma response element in the mouse pdx-1 promoter.
Volume: 283
Issue: 47
Pages: 32462-70
Publication
First Author: Chase LG
Year: 2007
Journal: Diabetes
Title: Islet-derived fibroblast-like cells are not derived via epithelial-mesenchymal transition from Pdx-1 or insulin-positive cells.
Volume: 56
Issue: 1
Pages: 3-7
Publication
First Author: Afelik S
Year: 2015
Journal: Dev Biol
Title: Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development.
Volume: 399
Issue: 2
Pages: 204-17
Publication
First Author: Svensson P
Year: 2009
Journal: Mol Cell Biol
Title: MFng is dispensable for mouse pancreas development and function.
Volume: 29
Issue: 8
Pages: 2129-38
Publication
First Author: Fujikura J
Year: 2006
Journal: Cell Metab
Title: Notch/Rbp-j signaling prevents premature endocrine and ductal cell differentiation in the pancreas.
Volume: 3
Issue: 1
Pages: 59-65
Publication
First Author: Krentz NAJ
Year: 2017
Journal: Dev Cell
Title: Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors.
Volume: 41
Issue: 2
Pages: 129-142.e6
Publication
First Author: Reinert RB
Year: 2013
Journal: Diabetes
Title: Vascular endothelial growth factor-a and islet vascularization are necessary in developing, but not adult, pancreatic islets.
Volume: 62
Issue: 12
Pages: 4154-64
Publication
First Author: Jonatan D
Year: 2014
Journal: PLoS One
Title: Sox17 regulates insulin secretion in the normal and pathologic mouse β cell.
Volume: 9
Issue: 8
Pages: e104675
Publication
First Author: Liu J
Year: 2013
Journal: Genesis
Title: Non-parallel recombination limits Cre-LoxP-based reporters as precise indicators of conditional genetic manipulation.
Volume: 51
Issue: 6
Pages: 436-42
Publication
First Author: Jimenez-Caliani AJ
Year: 2017
Journal: Cell Rep
Title: αE-Catenin Is a Positive Regulator of Pancreatic Islet Cell Lineage Differentiation.
Volume: 20
Issue: 6
Pages: 1295-1306
Publication
First Author: Kim SY
Year: 2017
Journal: J Biol Chem
Title: Loss of Cyclin-dependent Kinase 2 in the Pancreas Links Primary β-Cell Dysfunction to Progressive Depletion of β-Cell Mass and Diabetes.
Volume: 292
Issue: 9
Pages: 3841-3853
Publication
First Author: Martin D
Year: 2015
Journal: Dev Biol
Title: REST represses a subset of the pancreatic endocrine differentiation program.
Volume: 405
Issue: 2
Pages: 316-27
Publication
First Author: van Arensbergen J
Year: 2013
Journal: Genes Dev
Title: Ring1b bookmarks genes in pancreatic embryonic progenitors for repression in adult β cells.
Volume: 27
Issue: 1
Pages: 52-63
Publication  
First Author: Chen C
Year: 2019
Journal: Development
Title: Evidence of a developmental origin for β-cell heterogeneity using a dual lineage-tracing technology.
Volume: 146
Issue: 13
Publication
First Author: Gao N
Year: 2010
Journal: Mol Endocrinol
Title: Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell.
Volume: 24
Issue: 8
Pages: 1594-604
Publication
First Author: Dubois CL
Year: 2011
Journal: PLoS One
Title: Sox9-haploinsufficiency causes glucose intolerance in mice.
Volume: 6
Issue: 8
Pages: e23131
Publication
First Author: Schaffer AE
Year: 2010
Journal: Dev Cell
Title: Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.
Volume: 18
Issue: 6
Pages: 1022-9
Publication
First Author: Lynn FC
Year: 2007
Journal: Diabetes
Title: MicroRNA expression is required for pancreatic islet cell genesis in the mouse.
Volume: 56
Issue: 12
Pages: 2938-45
Publication  
First Author: Wells JM
Year: 2007
Journal: BMC Dev Biol
Title: Wnt/beta-catenin signaling is required for development of the exocrine pancreas.
Volume: 7
Pages: 4
Publication
First Author: Georgia S
Year: 2013
Journal: Genes Dev
Title: DNMT1 represses p53 to maintain progenitor cell survival during pancreatic organogenesis.
Volume: 27
Issue: 4
Pages: 372-7
Publication
First Author: Wu J
Year: 2017
Journal: PLoS One
Title: Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele.
Volume: 12
Issue: 9
Pages: e0184984
Publication  
First Author: Li LC
Year: 2018
Journal: EMBO Rep
Title: Single-cell transcriptomic analyses reveal distinct dorsal/ventral pancreatic programs.
Volume: 19
Issue: 10
Publication
First Author: Westmoreland JJ
Year: 2009
Journal: Dev Biol
Title: Pdk1 activity controls proliferation, survival, and growth of developing pancreatic cells.
Volume: 334
Issue: 1
Pages: 285-98
Publication
First Author: Ejarque M
Year: 2016
Journal: PLoS One
Title: Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8).
Volume: 11
Issue: 1
Pages: e0146273
Publication
First Author: Muñoz-Bravo JL
Year: 2013
Journal: Development
Title: GDNF is required for neural colonization of the pancreas.
Volume: 140
Issue: 17
Pages: 3669-79
Publication
First Author: Ait-Lounis A
Year: 2010
Journal: Diabetes
Title: The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression.
Volume: 59
Issue: 7
Pages: 1674-85
Publication
First Author: Wu X
Year: 2009
Journal: Diabetologia
Title: Perinatal survivin is essential for the establishment of pancreatic beta cell mass in mice.
Volume: 52
Issue: 10
Pages: 2130-41
Publication
First Author: Strom A
Year: 2007
Journal: Development
Title: Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas.
Volume: 134
Issue: 15
Pages: 2719-25
Publication
First Author: Marty-Santos L
Year: 2016
Journal: Development
Title: Pdx1 regulates pancreas tubulogenesis and E-cadherin expression.
Volume: 143
Issue: 1
Pages: 101-12
Publication
First Author: George NM
Year: 2012
Journal: Mol Cell Biol
Title: Hippo signaling regulates pancreas development through inactivation of Yap.
Volume: 32
Issue: 24
Pages: 5116-28
Publication
First Author: Hale MA
Year: 2014
Journal: Development
Title: The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.
Volume: 141
Issue: 16
Pages: 3123-33
Publication
First Author: Muñoz-Bravo JL
Year: 2016
Journal: PLoS One
Title: Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity.
Volume: 11
Issue: 10
Pages: e0164714
Publication
First Author: Lo B
Year: 2012
Journal: J Cell Biol
Title: Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways.
Volume: 199
Issue: 7
Pages: 1117-30
Publication
First Author: Stanger BZ
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Direct regulation of intestinal fate by Notch.
Volume: 102
Issue: 35
Pages: 12443-8
Publication
First Author: Kim DS
Year: 2018
Journal: Endocrinology
Title: GRP94 Is an Essential Regulator of Pancreatic β-Cell Development, Mass, and Function in Male Mice.
Volume: 159
Issue: 2
Pages: 1062-1073
Publication
First Author: Herrera PL
Year: 2002
Journal: Endocrine
Title: Pancreatic cell lineage analyses in mice.
Volume: 19
Issue: 3
Pages: 267-78
Publication        
First Author: Vanderbilt University
Year: 2020
Title: Labnodes
Publication
First Author: Murtaugh LC
Year: 2005
Journal: Development
Title: Beta-catenin is essential for pancreatic acinar but not islet development.
Volume: 132
Issue: 21
Pages: 4663-74
Publication
First Author: Mastracci TL
Year: 2011
Journal: Dev Biol
Title: Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression.
Volume: 359
Issue: 1
Pages: 1-11
Publication
First Author: Carrasco M
Year: 2012
Journal: J Clin Invest
Title: GATA4 and GATA6 control mouse pancreas organogenesis.
Volume: 122
Issue: 10
Pages: 3504-15
Publication
First Author: Rodríguez-Seguel E
Year: 2020
Journal: J Pathol
Title: Loss of GATA4 causes ectopic pancreas in the stomach.
Volume: 250
Issue: 4
Pages: 362-373
Publication
First Author: Xuan S
Year: 2016
Journal: Development
Title: GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling.
Volume: 143
Issue: 5
Pages: 780-6
Publication
First Author: Seymour PA
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: SOX9 is required for maintenance of the pancreatic progenitor cell pool.
Volume: 104
Issue: 6
Pages: 1865-70
Publication
First Author: Johansson JK
Year: 2010
Journal: Genesis
Title: N-cadherin is dispensable for pancreas development but required for beta-cell granule turnover.
Volume: 48
Issue: 6
Pages: 374-81
Publication
First Author: Vinckier NK
Year: 2020
Journal: Nat Commun
Title: LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development.
Volume: 11
Issue: 1
Pages: 2082
Publication
First Author: Escot S
Year: 2018
Journal: Nat Commun
Title: Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors.
Volume: 9
Issue: 1
Pages: 5082
Publication
First Author: Conrad E
Year: 2016
Journal: Am J Physiol Endocrinol Metab
Title: The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.
Volume: 310
Issue: 1
Pages: E91-E102
Publication
First Author: Petzold KM
Year: 2013
Journal: Development
Title: Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas.
Volume: 140
Issue: 1
Pages: 126-35
Publication
First Author: Lau J
Year: 2010
Journal: Diabetes
Title: Hedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult beta-cell function.
Volume: 59
Issue: 5
Pages: 1211-21
Publication
First Author: Hendley AM
Year: 2015
Journal: Dev Biol
Title: p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas.
Volume: 399
Issue: 1
Pages: 41-53
Publication
First Author: Westmoreland JJ
Year: 2012
Journal: Gastroenterology
Title: Pancreas-specific deletion of Prox1 affects development and disrupts homeostasis of the exocrine pancreas.
Volume: 142
Issue: 4
Pages: 999-1009.e6
Publication
First Author: Liu J
Year: 2019
Journal: Dev Cell
Title: Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity.
Volume: 48
Issue: 1
Pages: 49-63.e7
Publication
First Author: Nyeng P
Year: 2019
Journal: Dev Cell
Title: p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate.
Volume: 49
Issue: 1
Pages: 31-47.e9
Publication
First Author: Wei J
Year: 2014
Journal: Diabetes
Title: Osteocalcin promotes β-cell proliferation during development and adulthood through Gprc6a.
Volume: 63
Issue: 3
Pages: 1021-31
Publication
First Author: De Vas MG
Year: 2015
Journal: Development
Title: Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors.
Volume: 142
Issue: 5
Pages: 871-82
Publication
First Author: Shih HP
Year: 2012
Journal: Development
Title: A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation.
Volume: 139
Issue: 14
Pages: 2488-99
Publication
First Author: Gao T
Year: 2013
Journal: Gastroenterology
Title: Hippo signaling regulates differentiation and maintenance in the exocrine pancreas.
Volume: 144
Issue: 7
Pages: 1543-53, 1553.e1
Publication
First Author: Serafimidis I
Year: 2017
Journal: PLoS Biol
Title: Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling.
Volume: 15
Issue: 3
Pages: e2000949
Publication
First Author: Reinert RB
Year: 2014
Journal: Development
Title: Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding.
Volume: 141
Issue: 7
Pages: 1480-91
Publication
First Author: Nekrep N
Year: 2008
Journal: Development
Title: Signals from the neural crest regulate beta-cell mass in the pancreas.
Volume: 135
Issue: 12
Pages: 2151-60
Publication
First Author: Xu EE
Year: 2015
Journal: Diabetologia
Title: SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models.
Volume: 58
Issue: 5
Pages: 1013-23
Publication
First Author: Wang S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function.
Volume: 106
Issue: 24
Pages: 9715-20
Publication
First Author: Yang X
Year: 2020
Journal: Diabetes
Title: Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca2+ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response.
Volume: 69
Issue: 6
Pages: 1219-1231
Publication
First Author: Danilova T
Year: 2019
Journal: Diabetes
Title: MANF Is Required for the Postnatal Expansion and Maintenance of Pancreatic β-Cell Mass in Mice.
Volume: 68
Issue: 1
Pages: 66-80
Publication  
First Author: Pujadas G
Year: 2016
Journal: Sci Rep
Title: Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas.
Volume: 6
Pages: 19223
Publication
First Author: Talchai C
Year: 2012
Journal: Nat Genet
Title: Generation of functional insulin-producing cells in the gut by Foxo1 ablation.
Volume: 44
Issue: 4
Pages: 406-12, S1
Publication  
First Author: Norlin S
Year: 2018
Journal: Development
Title: The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival.
Volume: 145
Issue: 1
Publication
First Author: Zhang H
Year: 2009
Journal: Mech Dev
Title: Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation.
Volume: 126
Issue: 11-12
Pages: 958-73
Publication
First Author: Xuan S
Year: 2012
Journal: J Clin Invest
Title: Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis.
Volume: 122
Issue: 10
Pages: 3516-28
Publication
First Author: Wang S
Year: 2007
Journal: Mech Dev
Title: Loss of Myt1 function partially compromises endocrine islet cell differentiation and pancreatic physiological function in the mouse.
Volume: 124
Issue: 11-12
Pages: 898-910