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Search results 1 to 100 out of 114 for Pex5l

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
51555 | PEX5L
Type: gene
Organism: human
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Gene
471010 | PEX5L
Type: gene
Organism: chimpanzee
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Gene
488088 | PEX5L
Type: gene
Organism: dog, domestic
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Gene
531027 | PEX5L
Type: gene
Organism: cattle
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Gene
429155 | PEX5L
Type: gene
Organism: chicken
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Gene
708506 | PEX5L
Type: gene
Organism: macaque, rhesus
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Gene
100498559 | pex5l
Type: gene
Organism: frog, western clawed
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Gene
286937 | Pex5l
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1916672 | Pex5l
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
   
Probe: MGI:6180444
Assay Type: RNA in situ
Annotation Date: 2022-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7276179
Age: postnatal day 4
Specimen Label: S6e Pex5l
Detected: true
Specimen Num: 1
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Gene
100874040 | PEX5L-AS1
Type: gene
Organism: human
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Gene
101928790 | PEX5L-AS2
Type: gene
Organism: human
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Publication
22550182 | J:184786
First Author: Bankston JR
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels.
Volume: 109
Issue: 20
Pages: 7899-904
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Protein Coding Gene
MGP_CAROLIEiJ_G0024924 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0027145 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027105 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027074 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0027117 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026860 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1916672 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027563 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0026313 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026837 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026971 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026939 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027083 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026959 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027622 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026046 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0026387 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0026369 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025858 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
29662202 | J:271393
First Author: Yun S
Year: 2018
Journal: Nat Med
Title: Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive.
Volume: 24
Issue: 5
Pages: 658-666
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Publication
28213444 | J:240397
First Author: Srinivas KV
Year: 2017
Journal: J Neurosci
Title: The Dendrites of CA2 and CA1 Pyramidal Neurons Differentially Regulate Information Flow in the Cortico-Hippocampal Circuit.
Volume: 37
Issue: 12
Pages: 3276-3293
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Publication
23077068 | J:191246
First Author: Huang Z
Year: 2012
Journal: J Neurosci
Title: TRIP8b-independent trafficking and plasticity of adult cortical presynaptic HCN1 channels.
Volume: 32
Issue: 42
Pages: 14835-48
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Publication
29953635 | J:265918
First Author: Fisher DW
Year: 2018
Journal: J Neurochem
Title: HCN channels in the hippocampus regulate active coping behavior.
Volume: 146
Issue: 6
Pages: 753-766
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Publication
29168010 | J:275574
First Author: Zobeiri M
Year: 2018
Journal: Brain Struct Funct
Title: Modulation of thalamocortical oscillations by TRIP8b, an auxiliary subunit for HCN channels.
Volume: 223
Issue: 3
Pages: 1537-1564
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Publication
31932764 | J:292751
First Author: Munn RGK
Year: 2020
Journal: Nat Neurosci
Title: Entorhinal velocity signals reflect environmental geometry.
Volume: 23
Issue: 2
Pages: 239-251
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Publication
26459112 | J:228651
 
First Author: Heuermann RJ
Year: 2016
Journal: Neurobiol Dis
Title: Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy.
Volume: 85
Pages: 81-92
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GXD Expression
GXD Expression
     
Probe: MGI:3584973
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1647028
Stage: TS28
Assay Id: MGI:3585409
Age: postnatal day 6
Specimen Label: CNS
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:3584973
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585409
Age: postnatal day 0-1
Image: P0/1
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P0/1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3584973
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:3585409
Age: postnatal day 2-3
Image: P2/3
Note: Expression was detected in the outer neuroblastic layer, tentatively in the scleral outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3584973
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585409
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3584973
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585409
Age: postnatal adult
Image: Adult
Specimen Label: Adult
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6180444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191072
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pex2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6180444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191072
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pex2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6180444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191072
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pex2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6180444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191072
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pex2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6180444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191072
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pex2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6180444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191072
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pex2
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6180444
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191072
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pex2
Detected: true
Specimen Num: 7
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Publication
- | J:65160
   
First Author: Sano H
Year: 2000
Journal: GenBank Submission
Title: Mus musculus mRNA for PXR2, complete cds
Pages: AB032591
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Publication
23382386 | J:203510
First Author: Cao-Ehlker X
Year: 2013
Journal: J Biol Chem
Title: Up-regulation of hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) by specific interaction with K+ channel tetramerization domain-containing protein 3 (KCTD3).
Volume: 288
Issue: 11
Pages: 7580-9
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Publication
21555075 | J:174797
First Author: Piskorowski R
Year: 2011
Journal: Neuron
Title: TRIP8b splice forms act in concert to regulate the localization and expression of HCN1 channels in CA1 pyramidal neurons.
Volume: 70
Issue: 3
Pages: 495-509
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Publication
22363812 | J:232018
First Author: Wilkars W
Year: 2012
Journal: PLoS One
Title: Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms.
Volume: 7
Issue: 2
Pages: e32181
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Publication
24409334 | J:229656
First Author: Pan Y
Year: 2014
Journal: PLoS One
Title: TRIP8b is required for maximal expression of HCN1 in the mouse retina.
Volume: 9
Issue: 1
Pages: e85850
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Publication
19555649 | J:154954
First Author: Santoro B
Year: 2009
Journal: Neuron
Title: TRIP8b splice variants form a family of auxiliary subunits that regulate gating and trafficking of HCN channels in the brain.
Volume: 62
Issue: 6
Pages: 802-13
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Publication
21593326 | J:173355
First Author: Lewis AS
Year: 2011
Journal: J Neurosci
Title: Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice.
Volume: 31
Issue: 20
Pages: 7424-40
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Publication
15564593 | J:96808
First Author: Santoro B
Year: 2004
Journal: J Neurosci
Title: Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction.
Volume: 24
Issue: 47
Pages: 10750-62
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Publication
34163074 | J:323958
First Author: Di Bella DJ
Year: 2021
Journal: Nature
Title: Molecular logic of cellular diversification in the mouse cerebral cortex.
Volume: 595
Issue: 7868
Pages: 554-559
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Publication
23382219 | J:194542
First Author: Ghai R
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Volume: 110
Issue: 8
Pages: E643-52
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:346132
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
32189562 | -
First Author: Han Y
Year: 2020
Journal: Channels (Austin)
Title: The structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels.
Volume: 14
Issue: 1
Pages: 110-122
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Protein Domain
IPR024112 | PEX5L_vertebrates
Type: Family
Description: This entry represents the PEX5-related proteins (PEX5L, also known as TRIP8b) from vertebrates. It acts as an accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence [, ]. Interestingly, although PEX5L and PEX5 have structurally similar binding at their TPR domains, they bind to different substrates in vivo [].
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Protein Domain
IPR024111 | PEX5/PEX5L
Type: Family
Description: Peroxisomal proteins catalyse metabolic reactions. The import of proteins from the cytosol into the peroxisomes matrix depends on more than a dozen peroxin (PEX) proteins, among which PEX5 and PEX7 serve as receptors that shuttle proteins bearing one of two peroxisome-targeting signals (PTSs) into the organelle. PEX5 is the PTS1 receptor, while PEX7 is the PTS2 receptor. In plants, PEX7 depends on PEX5 binding to deliver PTS2 cargo into the peroxisome, and PEX7 also facilitates PEX5 accumulation and import of PTS1 cargo into peroxisomes [, ]. This entry include PEX5 (also known as PTS1R) from animals, fungi and plants. This entry also includes PEX5L from vertebrates. PEX5 binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import [, , ]. Based on subcellular localization and binding properties mammalian PEX5 may function as a regulator in an early step of the PTS1 protein import process []. PEX5L acts as an accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence [, ]. Interestingly, although PEX5 and PEX5L have structurally similar binding at their TPR domains, they bind to different substrates in vivo [].
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Publication
11606046 | -
First Author: Ito R
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Temperature-sensitive phenotype of Chinese hamster ovary cells defective in PEX5 gene.
Volume: 288
Issue: 2
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Year: 1998
Journal: Hum Mol Genet
Title: An isoform of pex5p, the human PTS1 receptor, is required for the import of PTS2 proteins into peroxisomes.
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