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Search results 1 to 100 out of 157 for Pex7

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Peroxisomal proteins catalyse metabolic reactions. The import of proteins from the cytosol into the peroxisomes matrix depends on more than a dozen peroxin (PEX) proteins, among which PEX5 and PEX7 serve as receptors that shuttle proteins bearing one of two peroxisome-targeting signals (PTSs) into the organelle. PEX5 is the PTS1 receptor, while PEX7 is the PTS2 receptor. In plants, PEX7 depends on PEX5 binding to deliver PTS2 cargo into the peroxisome, and PEX7 also facilitates PEX5 accumulation and import of PTS1 cargo into peroxisomes [, ]. This entry represents PEX7 from animals, fungi and plants. In plants it plays important roles in embryonic development, seedling establishment, and vegetative growth []. Budding yeast PEX7 homologue, Pas7, is necessary for import of thiolase (a PTS2-containing protein) []. In humans PEX7 has been linked to several diseases, such as Rhizomelic chondrodysplasia punctata 1 (RCDP1) []and Peroxisome biogenesis disorder 9B (PBD9B) [].
Publication
First Author: Braverman N
Year: 1997
Journal: Nat Genet
Title: Human PEX7 encodes the peroxisomal PTS2 receptor and is responsible for rhizomelic chondrodysplasia punctata.
Volume: 15
Issue: 4
Pages: 369-76
Publication
First Author: van den Brink DM
Year: 2003
Journal: Am J Hum Genet
Title: Identification of PEX7 as the second gene involved in Refsum disease.
Volume: 72
Issue: 2
Pages: 471-7
Publication
First Author: Ramón NM
Year: 2010
Journal: Mol Biol Cell
Title: Interdependence of the peroxisome-targeting receptors in Arabidopsis thaliana: PEX7 facilitates PEX5 accumulation and import of PTS1 cargo into peroxisomes.
Volume: 21
Issue: 7
Pages: 1263-71
Publication
First Author: Woodward AW
Year: 2005
Journal: Mol Biol Cell
Title: The Arabidopsis peroxisomal targeting signal type 2 receptor PEX7 is necessary for peroxisome function and dependent on PEX5.
Volume: 16
Issue: 2
Pages: 573-83
Publication
First Author: Braverman N
Year: 2010
Journal: Mol Genet Metab
Title: A Pex7 hypomorphic mouse model for plasmalogen deficiency affecting the lens and skeleton.
Volume: 99
Issue: 4
Pages: 408-16
Publication
First Author: Brites P
Year: 2003
Journal: Hum Mol Genet
Title: Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata.
Volume: 12
Issue: 18
Pages: 2255-67
Publication
First Author: Marzioch M
Year: 1994
Journal: EMBO J
Title: PAS7 encodes a novel yeast member of the WD-40 protein family essential for import of 3-oxoacyl-CoA thiolase, a PTS2-containing protein, into peroxisomes.
Volume: 13
Issue: 20
Pages: 4908-18
Protein
Organism: Mus musculus/domesticus
Length: 318  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: false
Publication  
First Author: Fallatah W
Year: 2022
Journal: Front Cell Dev Biol
Title: A Pex7 Deficient Mouse Series Correlates Biochemical and Neurobehavioral Markers to Genotype Severity-Implications for the Disease Spectrum of Rhizomelic Chondrodysplasia Punctata Type 1.
Volume: 10
Pages: 886316
Publication
First Author: Rodrigues TA
Year: 2014
Journal: Mol Cell Biol
Title: A PEX7-centered perspective on the peroxisomal targeting signal type 2-mediated protein import pathway.
Volume: 34
Issue: 15
Pages: 2917-28
Publication
First Author: Mukai S
Year: 2002
Journal: J Biol Chem
Title: Intracellular localization, function, and dysfunction of the peroxisome-targeting signal type 2 receptor, Pex7p, in mammalian cells.
Volume: 277
Issue: 11
Pages: 9548-61
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Fallatah W
Year: 2020
Journal: Dis Model Mech
Title: Oral administration of a synthetic vinyl-ether plasmalogen normalizes open field activity in a mouse model of rhizomelic chondrodysplasia punctata.
Volume: 13
Issue: 1
Publication
First Author: Lodhi IJ
Year: 2014
Journal: Cell Metab
Title: Peroxisomes: a nexus for lipid metabolism and cellular signaling.
Volume: 19
Issue: 3
Pages: 380-92
Publication  
First Author: Luoma AM
Year: 2015
Journal: Free Radic Biol Med
Title: Plasmalogen phospholipids protect internodal myelin from oxidative damage.
Volume: 84
Pages: 296-310
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289405
Age: embryonic day 1.5
Specimen Label: 2-cell-A1-1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289405
Age: embryonic day 1.5
Specimen Label: 2-cell-A1-2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289405
Age: embryonic day 1.5
Specimen Label: 2-cell-A2-1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289405
Age: embryonic day 1.5
Specimen Label: 2-cell-A2-2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289405
Age: embryonic day 1.5
Specimen Label: 2-cell-B1-1
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289405
Age: embryonic day 1.5
Specimen Label: 2-cell-B1-2
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289405
Age: embryonic day 1.5
Specimen Label: 2-cell-B2-1
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289405
Age: embryonic day 1.5
Specimen Label: 2-cell-B2-2
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289405
Age: embryonic day 1.5
Specimen Label: 2-cell-C1-1
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289405
Age: embryonic day 1.5
Specimen Label: 2-cell-C1-2
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289405
Age: embryonic day 1.5
Specimen Label: 2-cell-C2-1
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289405
Age: embryonic day 1.5
Specimen Label: 2-cell-C2-2
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-A1-1
Detected: false
Specimen Num: 13
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-A1-2
Detected: false
Specimen Num: 14
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-A2-1
Detected: false
Specimen Num: 15
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-A2-2
Detected: false
Specimen Num: 16
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-A3-1
Detected: false
Specimen Num: 17
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-A3-2
Detected: false
Specimen Num: 18
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-A4-1
Detected: false
Specimen Num: 19
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-A4-2
Detected: false
Specimen Num: 20
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-B1-1
Detected: false
Specimen Num: 21
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-B1-2
Detected: false
Specimen Num: 22
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-B2-1
Detected: true
Specimen Num: 23
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-B2-2
Detected: true
Specimen Num: 24
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-B3-1
Detected: false
Specimen Num: 25
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-B3-2
Detected: false
Specimen Num: 26
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-B4-1
Detected: false
Specimen Num: 27
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-B4-2
Detected: false
Specimen Num: 28
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-C1-1
Detected: true
Specimen Num: 29
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-C1-2
Detected: true
Specimen Num: 30
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-C2-1
Detected: true
Specimen Num: 31
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-C2-2
Detected: true
Specimen Num: 32
GXD Expression        
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-C3-1
Specimen Num: 33
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-C3-2
Detected: false
Specimen Num: 34
GXD Expression      
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-C4-1
Detected: true
Specimen Num: 35
GXD Expression        
Probe: MGI:5288974
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289405
Age: embryonic day 2.0
Specimen Label: 4-cell-C4-2
Specimen Num: 36
Publication
First Author: Mizuno Y
Year: 2013
Journal: PLoS Genet
Title: Tysnd1 deficiency in mice interferes with the peroxisomal localization of PTS2 enzymes, causing lipid metabolic abnormalities and male infertility.
Volume: 9
Issue: 2
Pages: e1003286
Publication
First Author: da Silva TF
Year: 2014
Journal: J Clin Invest
Title: Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination.
Volume: 124
Issue: 6
Pages: 2560-70
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
Publication
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer