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Search results 1 to 100 out of 118 for Phactr1

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Hits by Category

Hits by Strain

Type Details Score
Gene
221692 | PHACTR1
Type: gene
Organism: human
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Gene
100216198 | phactr1
Type: gene
Organism: frog, western clawed
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Gene
306844 | Phactr1
Type: gene
Organism: rat
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Gene
462438 | PHACTR1
Type: gene
Organism: chimpanzee
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Gene
478723 | PHACTR1
Type: gene
Organism: dog, domestic
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Gene
537594 | PHACTR1
Type: gene
Organism: cattle
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Gene
395093 | PHACTR1
Type: gene
Organism: chicken
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Gene
100334776 | phactr1
Type: gene
Organism: zebrafish
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Gene
700226 | PHACTR1
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR029987 | Phactr1
Type: Family
Description: Phosphatase and actin regulator (PHACTR) family members bind to actin and regulate protein phosphatase 1 (PP1) []. PHACTRs are comprised of four family members (Phactr1-4) with distinct expression patterns in the adult brain. They appear to be involved in the regulation of synaptic plasticity via modulating PP1 activity []. Phactr1 is highly enriched in mature neurons, and appears to play a role in development of dendritic spines and axons []. In non-neuronal cells, it plays significant roles in actin remodelling, affecting tubulogenesis and lamellipodial dynamics []. Phactr1 is involved in the migration and actin dynamics of breast cancer cells []. The structure of Phactr1 has been solved [].
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Protein Coding Gene
MGI:2659021 | Phactr1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22766235 | J:192507
 
First Author: Kim JY
Year: 2012
Journal: Neuroscience
Title: Different expression patterns of Phactr family members in normal and injured mouse brain.
Volume: 221
Pages: 37-46
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Publication
23041370 | -
First Author: Mouilleron S
Year: 2012
Journal: Structure
Title: Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity.
Volume: 20
Issue: 11
Pages: 1960-70
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Publication
30256902 | J:276495
First Author: Hamada N
Year: 2018
Journal: Brain
Title: De novo PHACTR1 mutations in West syndrome and their pathophysiological effects.
Volume: 141
Issue: 11
Pages: 3098-3114
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Publication
22976292 | J:196227
First Author: Wiezlak M
Year: 2012
Journal: J Cell Sci
Title: G-actin regulates the shuttling and PP1 binding of the RPEL protein Phactr1 to control actomyosin assembly.
Volume: 125
Issue: Pt 23
Pages: 5860-72
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Publication
33630758 | J:305798
 
First Author: Kasikara C
Year: 2021
Journal: J Clin Invest
Title: Deficiency of macrophage PHACTR1 impairs efferocytosis and promotes atherosclerotic plaque necrosis.
Volume: 131
Issue: 8
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Publication
35653516 | J:335230
First Author: Wood A
Year: 2023
Journal: Cardiovasc Res
Title: PHACTR1 modulates vascular compliance but not endothelial function: a translational study.
Volume: 119
Issue: 2
Pages: 599-610
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Publication
28803787 | J:261960
 
First Author: Ito H
Year: 2018
Journal: Neurosci Res
Title: Expression analyses of Phactr1 (phosphatase and actin regulator 1) during mouse brain development.
Volume: 128
Pages: 50-57
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Publication
23479725 | -
First Author: Fils-Aimé N
Year: 2013
Journal: J Biol Chem
Title: MicroRNA-584 and the protein phosphatase and actin regulator 1 (PHACTR1), a new signaling route through which transforming growth factor-β Mediates the migration and actin dynamics of breast cancer cells.
Volume: 288
Issue: 17
Pages: 11807-23
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Publication
21939755 | -
First Author: Allain B
Year: 2012
Journal: Cell Signal
Title: Neuropilin-1 regulates a new VEGF-induced gene, Phactr-1, which controls tubulogenesis and modulates lamellipodial dynamics in human endothelial cells.
Volume: 24
Issue: 1
Pages: 214-23
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Protein
Q2M3X8
Organism: Mus musculus/domesticus
Length: 580  
Fragment?: false
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Protein
A0A668KL56
Organism: Mus musculus/domesticus
Length: 205  
Fragment?: true
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Protein
B1B1B8
Organism: Mus musculus/domesticus
Length: 557  
Fragment?: false
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Protein
Q80ZP7
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: false
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Publication
15107502 | -
First Author: Allen PB
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins.
Volume: 101
Issue: 18
Pages: 7187-92
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Publication
32975518 | J:299011
   
First Author: Fedoryshchak RO
Year: 2020
Journal: Elife
Title: Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Volume: 9
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Publication
35387477 | J:341800
First Author: Rubin S
Year: 2022
Journal: Arterioscler Thromb Vasc Biol
Title: PHACTR-1 (Phosphatase and Actin Regulator 1) Deficiency in Either Endothelial or Smooth Muscle Cells Does Not Predispose Mice to Nonatherosclerotic Arteriopathies in 3 Transgenic Mice.
Volume: 42
Issue: 5
Pages: 597-609
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Protein Coding Gene
MGP_CAROLIEiJ_G0018465 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020449 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020427 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020445 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020244 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2659021 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020878 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019759 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020205 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020327 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020306 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020402 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020335 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020921 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019514 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019821 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019533 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019344 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1909527
Pattern: Ubiquitous
Stage: TS27
Assay Id: MGI:7469616
Age: postnatal day 7
Note: Ubiquitous expression in areas where neuronal cell bodies are enriched.
Specimen Label: 1I
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1909528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7469616
Age: postnatal adult
Specimen Label: 3D
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3533828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7469616
Age: postnatal adult
Specimen Label: 3F
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586087
Age: postnatal day 8-10
Specimen Label: P8/10
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586087
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
   
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7469616
Age: postnatal adult
Specimen Label: 3E
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778727
Pattern: Ubiquitous
Stage: TS27
Assay Id: MGI:7469616
Age: postnatal day 7
Note: Ubiquitous expression in areas where neuronal cell bodies are enriched.
Specimen Label: 1I
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7469616
Age: postnatal adult
Specimen Label: 3F
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7469616
Age: embryonic day 16.0
Specimen Label: 1E inset
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Ubiquitous
Stage: TS27
Assay Id: MGI:7469616
Age: postnatal day 7
Note: Ubiquitous expression in areas where neuronal cell bodies are enriched.
Specimen Label: 1I
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7469616
Age: postnatal adult
Specimen Label: 3D
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3525327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7469616
Age: postnatal day 7
Note: Only marginal expression in fiber-containing regions.
Specimen Label: 1I
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3561628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7469616
Age: postnatal adult
Specimen Label: 3D
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Pattern: Ubiquitous
Stage: TS27
Assay Id: MGI:7469616
Age: postnatal day 7
Note: Ubiquitous expression in areas where neuronal cell bodies are enriched.
Specimen Label: 1I
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7469616
Age: postnatal adult
Specimen Label: 3E
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586087
Age: postnatal day 6
Note: Expression was widespread.
Specimen Label: CNS
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1647024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7469616
Age: embryonic day 16.0
Note: Abundant expression in central nervous system.
Specimen Label: 1E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3586087
Age: embryonic day 16.0
Note: Expression was widespread.
Specimen Label: Embryo
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:7469616
Age: embryonic day 16.0
Note: Weak expression in peripheral tissues.
Specimen Label: 1E
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3586087
Age: embryonic day 18.0
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E18
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3586087
Age: postnatal day 0-1
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P0/1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3586087
Age: postnatal day 2-3
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586087
Age: postnatal day 4-5
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586087
Age: postnatal day 6-7
Specimen Label: P6/7
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586087
Age: postnatal day 8-10
Specimen Label: P8/10
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3586087
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3586087
Age: embryonic day 16.0
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E16
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7469616
Age: postnatal adult
Specimen Label: 3E
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7469616
Age: postnatal adult
Specimen Label: 3B
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7469616
Age: postnatal adult
Specimen Label: 3C
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:7469515
Assay Type: RNA in situ
Annotation Date: 2023-05-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7469616
Age: postnatal adult
Note: Expression distributed in most brain regions containing neurons.
Specimen Label: 3A
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:3586087
Age: embryonic day 12.0
Note: Expression was detected in a subset of cells in the outer neuroblastic layer.
Specimen Label: E12
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3584974
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3586087
Age: embryonic day 14.0
Note: Expression was detected in a subset of cells in the outer neuroblastic layer.
Specimen Label: E14
Detected: true
Specimen Num: 2
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Publication
- | J:83243
   
First Author: Strausberg R
Year: 2003
Journal: GenBank Submission
Title: Mus musculus, similar to Q9H4T4 like, clone IMAGE: 6469030, mRNA, partial cds
Pages: BC048407
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Publication
16359841 | J:105793
First Author: de Chaldée M
Year: 2006
Journal: Genomics
Title: Capucin: a novel striatal marker down-regulated in rodent models of Huntington disease.
Volume: 87
Issue: 2
Pages: 200-7
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Publication
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