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Search results 1 to 100 out of 493 for Phex

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Type Details Score
Gene
5251 | PHEX
Type: gene
Organism: human
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Gene
536029 | PHEX
Type: gene
Organism: cattle
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Gene
395777 | PHEX
Type: gene
Organism: chicken
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Gene
386969 | phex
Type: gene
Organism: zebrafish
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Gene
697025 | PHEX
Type: gene
Organism: macaque, rhesus
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Gene
100496470 | phex
Type: gene
Organism: frog, western clawed
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Gene
119868400 | PHEX
Type: gene
Organism: dog, domestic
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Gene
25512 | Phex
Type: gene
Organism: rat
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Gene
465533 | PHEX
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:107489 | Phex
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
A2ICR0
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: false
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Publication
17710565 | J:136463
First Author: Xiong X
Year: 2008
Journal: J Biomed Sci
Title: A novel Phex mutation with defective glycosylation causes hypophosphatemia and rickets in mice.
Volume: 15
Issue: 1
Pages: 47-59
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GXD Expression
GXD Expression
     
Probe: MGI:7491754
Assay Type: RT-PCR
Annotation Date: 2023-06-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1768125
Stage: TS25
Assay Id: MGI:7491759
Age: embryonic day 17.5
Specimen Label: Phex
Detected: true
Specimen Num: 1
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Publication
11517178 | J:71057
First Author: Liu S
Year: 2001
Journal: Endocrinology
Title: Cloning and characterization of the proximal murine Phex promoter.
Volume: 142
Issue: 9
Pages: 3987-95
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Gene
100873942 | PHEX-AS1
Type: gene
Organism: human
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Publication
11159866 | J:67356
First Author: Miao D
Year: 2001
Journal: Endocrinology
Title: Osteomalacia in hyp mice is associated with abnormal phex expression and with altered bone matrix protein expression and deposition.
Volume: 142
Issue: 2
Pages: 926-39
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Publication
18597632 | J:153409
First Author: Addison WN
Year: 2008
Journal: J Bone Miner Res
Title: MEPE-ASARM peptides control extracellular matrix mineralization by binding to hydroxyapatite: an inhibition regulated by PHEX cleavage of ASARM.
Volume: 23
Issue: 10
Pages: 1638-49
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Publication
11713245 | J:74324
First Author: Liu S
Year: 2002
Journal: J Biol Chem
Title: Overexpression of Phex in osteoblasts fails to rescue the Hyp mouse phenotype.
Volume: 277
Issue: 5
Pages: 3686-97
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Publication
15029877 | J:88352
First Author: Lorenz-Depiereux B
Year: 2004
Journal: Mamm Genome
Title: New intragenic deletions in the Phex gene clarify X-linked hypophosphatemia-related abnormalities in mice.
Volume: 15
Issue: 3
Pages: 151-61
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Publication
23028440 | J:192046
First Author: Han F
Year: 2012
Journal: PLoS One
Title: Mutation in Phex gene predisposes BALB/c-Phex(Hyp-Duk)/Y mice to otitis media.
Volume: 7
Issue: 9
Pages: e43010
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Publication
9063736 | J:38621
First Author: Strom TM
Year: 1997
Journal: Hum Mol Genet
Title: Pex gene deletions in Gy and Hyp mice provide mouse models for X-linked hypophosphatemia.
Volume: 6
Issue: 2
Pages: 165-71
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Publication
11018258 | J:65004
First Author: Hines ER
Year: 2000
Journal: Biochim Biophys Acta
Title: Molecular cloning of the murine PHEX gene promoter.
Volume: 1493
Issue: 3
Pages: 333-6
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Publication
10087298 | J:54052
First Author: Wang L
Year: 1999
Journal: Mamm Genome
Title: Evidence for Phex haploinsufficiency in murine X-linked hypophosphatemia.
Volume: 10
Issue: 4
Pages: 385-9
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Publication
22573557 | J:196537
First Author: Owen C
Year: 2012
Journal: J Cell Biochem
Title: A novel Phex mutation in a new mouse model of hypophosphatemic rickets.
Volume: 113
Issue: 7
Pages: 2432-41
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Publication
17942069 | J:129885
First Author: Onishi T
Year: 2008
Journal: Arch Oral Biol
Title: Phex mutation causes overexpression of FGF23 in teeth.
Volume: 53
Issue: 2
Pages: 99-104
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Publication
11811562 | J:112483
First Author: Thompson DL
Year: 2002
Journal: J Bone Miner Res
Title: Ontogeny of Phex/PHEX protein expression in mouse embryo and subcellular localization in osteoblasts.
Volume: 17
Issue: 2
Pages: 311-20
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Publication
22006791 | J:196643
First Author: Ichikawa S
Year: 2012
Journal: J Bone Miner Res
Title: A Phex mutation in a murine model of X-linked hypophosphatemia alters phosphate responsiveness of bone cells.
Volume: 27
Issue: 2
Pages: 453-60
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Publication
15940367 | J:111519
First Author: Erben RG
Year: 2005
Journal: J Bone Miner Res
Title: Overexpression of human PHEX under the human beta-actin promoter does not fully rescue the Hyp mouse phenotype.
Volume: 20
Issue: 7
Pages: 1149-60
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Publication
8812412 | J:34935
First Author: Du L
Year: 1996
Journal: Genomics
Title: cDNA cloning of the murine Pex gene implicated in X-linked hypophosphatemia and evidence for expression in bone.
Volume: 36
Issue: 1
Pages: 22-8
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Publication
9077527 | J:39093
First Author: Beck L
Year: 1997
Journal: J Clin Invest
Title: Pex/PEX tissue distribution and evidence for a deletion in the 3' region of the Pex gene in X-linked hypophosphatemic mice.
Volume: 99
Issue: 6
Pages: 1200-9
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Publication
24839967 | J:217349
First Author: Zelenchuk LV
Year: 2014
Journal: PLoS One
Title: PHEX mimetic (SPR4-peptide) corrects and improves HYP and wild type mice energy-metabolism.
Volume: 9
Issue: 5
Pages: e97326
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Publication
12414538 | J:79953
First Author: Carpinelli MR
Year: 2002
Journal: Am J Pathol
Title: An ethyl-nitrosourea-induced point mutation in phex causes exon skipping, x-linked hypophosphatemia, and rickets.
Volume: 161
Issue: 5
Pages: 1925-33
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Publication
18172553 | J:131043
First Author: Yuan B
Year: 2008
Journal: J Clin Invest
Title: Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia.
Volume: 118
Issue: 2
Pages: 722-34
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Publication
15050894 | J:89258
First Author: Miao D
Year: 2004
Journal: Bone
Title: Cartilage abnormalities are associated with abnormal Phex expression and with altered matrix protein and MMP-9 localization in Hyp mice.
Volume: 34
Issue: 4
Pages: 638-47
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Publication
36011266 | J:335128
 
First Author: El Hakam C
Year: 2022
Journal: Genes (Basel)
Title: PHEX(L222P) Mutation Increases Phex Expression in a New ENU Mouse Model for XLH Disease.
Volume: 13
Issue: 8
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Publication
10934642 | J:157605
First Author: Ruchon AF
Year: 2000
Journal: J Bone Miner Res
Title: Developmental expression and tissue distribution of Phex protein: effect of the Hyp mutation and relationship to bone markers.
Volume: 15
Issue: 8
Pages: 1440-50
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Publication
26051469 | J:228153
 
First Author: Zelenchuk LV
Year: 2015
Journal: Bone
Title: Age dependent regulation of bone-mass and renal function by the MEPE ASARM-motif.
Volume: 79
Pages: 131-42
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Publication
22991293 | J:323274
First Author: Barros NM
Year: 2013
Journal: J Bone Miner Res
Title: Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia.
Volume: 28
Issue: 3
Pages: 688-99
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Publication
9467015 | J:46360
First Author: Lorenz B
Year: 1998
Journal: Hum Mol Genet
Title: Spermine deficiency in Gy mice caused by deletion of the spermine synthase gene.
Volume: 7
Issue: 3
Pages: 541-7
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Publication
15459188 | J:95185
First Author: Wang X
Year: 2004
Journal: J Biol Chem
Title: Spermine synthesis is required for normal viability, growth, and fertility in the mouse.
Volume: 279
Issue: 49
Pages: 51370-5
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Publication
11023830 | J:65535
 
First Author: Mackintosh CA
Year: 2000
Journal: Biochem J
Title: Effect of spermine synthase deficiency on polyamine biosynthesis and content in mice and embryonic fibroblasts, and the sensitivity of fibroblasts to 1,3-bis-(2-chloroethyl)-N-nitrosourea.
Volume: 351 Pt 2
Pages: 439-47
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Publication
1528020 | J:3136
First Author: Scriver CR
Year: 1992
Journal: J Inherit Metab Dis
Title: X-linked hypophosphataemia: a homologous phenotype in humans and mice with unusual organ-specific gene dosage.
Volume: 15
Issue: 4
Pages: 610-24
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Publication
- | J:64263
 
First Author: Lyon MF
Year: 1960
Journal: Mouse News Lett
Title: Gy - gyro
Volume: 22
Pages: 30
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Publication
- | J:26058
First Author: Meyer RA
Year: 1994
Journal: Endocrine
Title: Measurement of parathyroid hormone in the mouse: secondary hyperparathyroidism in the X-linked hypophosphatemic (Gyro, gy) mouse.
Volume: 2
Issue: 12
Pages: 1127-1132
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Publication
8141332 | J:17268
First Author: Thornton SW
Year: 1994
Journal: Am J Physiol
Title: X-linked hypophosphatemic Gy mice: renal tubular maximum for phosphate vs. brush-border transport after low-P diet.
Volume: 266
Issue: 2 Pt 2
Pages: F309-15
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Publication
8927512 | J:33927
First Author: Beck L
Year: 1996
Journal: Pflugers Arch
Title: Renal expression of Na+-phosphate cotransporter mRNA and protein: effect of the Gy mutation and low phosphate diet.
Volume: 431
Issue: 6
Pages: 936-41
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Publication
10069185 | J:56014
First Author: Tenenhouse HS
Year: 1999
Journal: Nephrol Dial Transplant
Title: X-linked hypophosphataemia: a homologous disorder in humans and mice.
Volume: 14
Issue: 2
Pages: 333-41
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Publication
8266820 | J:17152
First Author: Woodward JE
Year: 1993
Journal: J Bone Miner Res
Title: Intestinal malabsorption of 45calcium in young Gy mice, a second model for X-linked hypophosphatemia.
Volume: 8
Issue: 11
Pages: 1281-90
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Publication
8717533 | J:36180
First Author: Meyer RA Jr
Year: 1996
Journal: Bone
Title: Effects of altered diet on serum levels of 1,25-dihydroxyvitamin D and parathyroid hormone in X-linked hypophosphatemic (Hyp and Gy) mice.
Volume: 18
Issue: 1
Pages: 23-8
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Publication
1612032 | J:1824
First Author: Tenenhouse HS
Year: 1992
Journal: Endocrinology
Title: Renal phosphate transport and vitamin D metabolism in X-linked hypophosphatemic Gy mice: responses to phosphate deprivation.
Volume: 131
Issue: 1
Pages: 51-6
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Publication
1962291 | J:1654
First Author: Shetty NS
Year: 1991
Journal: Teratology
Title: Craniofacial abnormalities in mice with X-linked hypophosphatemic genes (Hyp or Gy).
Volume: 44
Issue: 4
Pages: 463-72
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Publication
7853101 | J:24017
First Author: Meyer RA Jr
Year: 1995
Journal: J Orthop Res
Title: Femoral abnormalities and vitamin D metabolism in X-linked hypophosphatemic (Hyp and Gy) mice.
Volume: 13
Issue: 1
Pages: 30-40
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Publication
- | J:13833
 
First Author: Lyon MF
Year: 1980
Journal: Mouse News Lett
Title: Relation of gyro and hypophosphataemia
Volume: 62
Pages: 49
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Publication
8635692 | J:33265
First Author: Collins JF
Year: 1996
Journal: FASEB J
Title: The molecular defect in the renal sodium-phosphate transporter expression pathway of Gyro (Gy) mice is distinct from that of hypophosphatemic (Hyp) mice.
Volume: 10
Issue: 7
Pages: 751-9
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Publication
9362326 | J:43908
First Author: Econs MJ
Year: 1997
Journal: Am J Physiol
Title: Positional cloning of the PEX gene: new insights into the pathophysiology of X-linked hypophosphatemic rickets.
Volume: 273
Issue: 4 Pt 2
Pages: F489-98
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Publication
3460077 | J:8335
First Author: Lyon MF
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: The Gy mutation: another cause of X-linked hypophosphatemia in mouse.
Volume: 83
Issue: 13
Pages: 4899-903
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Publication
9545633 | J:47232
First Author: Meyer RA Jr
Year: 1998
Journal: Genomics
Title: Partial deletion of both the spermine synthase gene and the Pex gene in the X-linked hypophosphatemic, gyro (Gy) mouse.
Volume: 48
Issue: 3
Pages: 289-95
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Publication
8691720 | J:32872
First Author: Tenenhouse HS
Year: 1996
Journal: Kidney Int
Title: Renal Na(+)-phosphate cotransporter gene expression in X-linked Hyp and Gy mice.
Volume: 49
Issue: 4
Pages: 1027-32
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Publication
- | J:28887
First Author: Carter TC
Year: 1960
Journal: Genet Res
Title: The genetic sensitivity to X-rays of mouse foetal gonads.
Volume: 1
Issue: 3
Pages: 351-5
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Publication
18289812 | J:132678
First Author: Megerian CA
Year: 2008
Journal: Hear Res
Title: A mouse model with postnatal endolymphatic hydrops and hearing loss.
Volume: 237
Issue: 1-2
Pages: 90-105
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Publication
30120363 | J:278526
First Author: Pi M
Year: 2018
Journal: Sci Rep
Title: Cardiovascular Interactions between Fibroblast Growth Factor-23 and Angiotensin II.
Volume: 8
Issue: 1
Pages: 12398
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Publication
24601885 | J:210730
First Author: Ma Y
Year: 2014
Journal: Endocrinology
Title: Neither absence nor excess of FGF23 disturbs murine fetal-placental phosphorus homeostasis or prenatal skeletal development and mineralization.
Volume: 155
Issue: 5
Pages: 1596-605
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Publication
27929669 | J:246176
First Author: Ma Y
Year: 2017
Journal: Endocrinology
Title: FGF23 Is Not Required to Regulate Fetal Phosphorus Metabolism but Exerts Effects Within 12 Hours After Birth.
Volume: 158
Issue: 2
Pages: 252-263
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Publication
12900584 | J:85297
First Author: Sabbagh Y
Year: 2002
Journal: Cytogenet Genome Res
Title: The X chromosome deletion in HYP mice extends into the intergenic region but does not include the SAT gene downstream from Phex.
Volume: 99
Issue: 1-4
Pages: 344-9
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Publication
21854633 | J:237170
 
First Author: Moriyama K
Year: 2011
Journal: J Biomed Sci
Title: Kbus/Idr, a mutant mouse strain with skeletal abnormalities and hypophosphatemia: identification as an allele of 'Hyp'.
Volume: 18
Pages: 60
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Publication
23266491 | J:319019
First Author: Seitz S
Year: 2013
Journal: Bone
Title: Retinol deprivation partially rescues the skeletal mineralization defects of Phex-deficient Hyp mice.
Volume: 53
Issue: 1
Pages: 231-8
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Publication
29878089 | J:264826
First Author: Kaneko I
Year: 2018
Journal: Endocrinology
Title: Eldecalcitol Causes FGF23 Resistance for Pi Reabsorption and Improves Rachitic Bone Phenotypes in the Male Hyp Mouse.
Volume: 159
Issue: 7
Pages: 2741-2758
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Publication
25460577 | J:217457
 
First Author: Zelenchuk LV
Year: 2015
Journal: Bone
Title: SPR4-peptide alters bone metabolism of normal and HYP mice.
Volume: 72
Pages: 23-33
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Publication
14751570 | J:87808
First Author: Qiu ZQ
Year: 2004
Journal: Bone
Title: Effect of gene dose and parental origin on bone histomorphometry in X-linked Hyp mice.
Volume: 34
Issue: 1
Pages: 134-9
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Publication
16005844 | J:104579
First Author: Ogawa T
Year: 2006
Journal: Arch Oral Biol
Title: Dentinal defects in Hyp mice not caused by hypophosphatemia alone.
Volume: 51
Issue: 1
Pages: 58-63
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Publication
36278488 | J:331927
 
First Author: Buck A
Year: 2022
Journal: JCI Insight
Title: Spatial metabolomics reveals upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice.
Volume: 7
Issue: 20
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Publication
19656036 | J:237176
First Author: Fong H
Year: 2009
Journal: J Periodontol
Title: Aberrant cementum phenotype associated with the hypophosphatemic hyp mouse.
Volume: 80
Issue: 8
Pages: 1348-54
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Publication
28764922 | J:257795
 
First Author: Coyac BR
Year: 2017
Journal: Bone
Title: Tissue-specific mineralization defects in the periodontium of the Hyp mouse model of X-linked hypophosphatemia.
Volume: 103
Pages: 334-346
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Publication
15054142 | J:106264
First Author: Meyer MH
Year: 2004
Journal: Physiol Genomics
Title: The genomic response of the mouse kidney to low-phosphate diet is altered in X-linked hypophosphatemia.
Volume: 18
Issue: 1
Pages: 4-11
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Publication
28728941 | J:257817
 
First Author: Leifheit-Nestler M
Year: 2017
Journal: Bone
Title: Comparison of calcimimetic R568 and calcitriol in mineral homeostasis in the Hyp mouse, a murine homolog of X-linked hypophosphatemia.
Volume: 103
Pages: 224-232
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Publication
34523743 | J:323272
First Author: Delsmann MM
Year: 2021
Journal: J Bone Miner Res
Title: Conductive Hearing Loss in the Hyp Mouse Model of X-Linked Hypophosphatemia Is Accompanied by Hypomineralization of the Auditory Ossicles.
Volume: 36
Issue: 12
Pages: 2317-2328
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Publication
22334725 | J:183792
First Author: Zhang MY
Year: 2012
Journal: Endocrinology
Title: Chronic inhibition of ERK1/2 signaling improves disordered bone and mineral metabolism in hypophosphatemic (Hyp) mice.
Volume: 153
Issue: 4
Pages: 1806-16
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Publication
34537437 | J:323275
 
First Author: Carpenter KA
Year: 2022
Journal: Bone
Title: Sclerostin antibody improves phosphate metabolism hormones, bone formation rates, and bone mass in adult Hyp mice.
Volume: 154
Pages: 116201
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Publication
22886699 | J:233262
First Author: Yuan B
Year: 2013
Journal: J Bone Miner Res
Title: Hexa-D-arginine treatment increases 7B2•PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype.
Volume: 28
Issue: 1
Pages: 56-72
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Publication
15843468 | J:150696
First Author: Liu S
Year: 2005
Journal: J Am Soc Nephrol
Title: Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked hypophosphatemia.
Volume: 16
Issue: 6
Pages: 1645-53
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Publication
21312267 | J:233115
First Author: Atkins GJ
Year: 2011
Journal: J Bone Miner Res
Title: Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism.
Volume: 26
Issue: 7
Pages: 1425-36
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Publication
16449303 | J:110579
First Author: Liu S
Year: 2006
Journal: Am J Physiol Endocrinol Metab
Title: Pathogenic role of Fgf23 in Hyp mice.
Volume: 291
Issue: 1
Pages: E38-49
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Publication
12952859 | J:87132
First Author: Tenenhouse HS
Year: 2003
Journal: Am J Physiol Renal Physiol
Title: Differential effects of Npt2a gene ablation and X-linked Hyp mutation on renal expression of Npt2c.
Volume: 285
Issue: 6
Pages: F1271-8
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Publication
19952276 | J:158461
First Author: Brownstein CA
Year: 2010
Journal: Endocrinology
Title: Increased bone volume and correction of HYP mouse hypophosphatemia in the Klotho/HYP mouse.
Volume: 151
Issue: 2
Pages: 492-501
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Publication
19556340 | J:225037
First Author: Liu S
Year: 2009
Journal: Mol Endocrinol
Title: Novel regulators of Fgf23 expression and mineralization in Hyp bone.
Volume: 23
Issue: 9
Pages: 1505-18
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Publication
23652555 | J:318824
 
First Author: Uchihashi K
Year: 2013
Journal: Contrib Nephrol
Title: FGF23-induced hypophosphatemia persists in Hyp mice deficient in the WNT coreceptor Lrp6.
Volume: 180
Pages: 124-37
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Publication
17848631 | J:129380
First Author: Liu S
Year: 2007
Journal: Am J Physiol Endocrinol Metab
Title: Distinct roles for intrinsic osteocyte abnormalities and systemic factors in regulation of FGF23 and bone mineralization in Hyp mice.
Volume: 293
Issue: 6
Pages: E1636-44
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Publication
16123154 | J:129835
First Author: Perwad F
Year: 2005
Journal: Endocrinology
Title: Dietary and serum phosphorus regulate fibroblast growth factor 23 expression and 1,25-dihydroxyvitamin D metabolism in mice.
Volume: 146
Issue: 12
Pages: 5358-64
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Publication
23038738 | J:192371
First Author: Karaplis AC
Year: 2012
Journal: Endocrinology
Title: Mineralizing enthesopathy is a common feature of renal phosphate-wasting disorders attributed to FGF23 and is exacerbated by standard therapy in hyp mice.
Volume: 153
Issue: 12
Pages: 5906-17
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Publication
9141502 | J:39973
First Author: Turner AJ
Year: 1997
Journal: FASEB J
Title: Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX.
Volume: 11
Issue: 5
Pages: 355-64
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Publication
15976027 | J:99866
First Author: Sabbagh Y
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes.
Volume: 102
Issue: 27
Pages: 9637-42
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Publication
34326685 | J:323276
First Author: Wang K
Year: 2021
Journal: Int J Biol Sci
Title: Osteocytes but not osteoblasts directly build mineralized bone structures.
Volume: 17
Issue: 10
Pages: 2430-2448
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Publication
22930691 | J:225089
First Author: Martin A
Year: 2012
Journal: Mol Endocrinol
Title: Overexpression of the DMP1 C-terminal fragment stimulates FGF23 and exacerbates the hypophosphatemic rickets phenotype in Hyp mice.
Volume: 26
Issue: 11
Pages: 1883-95
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Publication
12791601 | J:84261
First Author: Quarles LD
Year: 2003
Journal: Am J Physiol Endocrinol Metab
Title: FGF23, PHEX, and MEPE regulation of phosphate homeostasis and skeletal mineralization.
Volume: 285
Issue: 1
Pages: E1-9
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Publication
24710520 | J:215016
First Author: Miyagawa K
Year: 2014
Journal: PLoS One
Title: Dysregulated gene expression in the primary osteoblasts and osteocytes isolated from hypophosphatemic Hyp mice.
Volume: 9
Issue: 4
Pages: e93840
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Protein Coding Gene
MGP_CAROLIEiJ_G0033522 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0036216 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0036186 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0036114 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0036179 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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