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Search results 1 to 100 out of 599 for Picalm

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0.022s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Domain
Type: Family
Description: PICALM (also known as clathrin assembly lymphoid myeloid leukemia protein, CALM) is a phosphatidylinositol-binding clathrin assembly protein that plays important roles in clathrin-mediated endocytosis in all cell types [, ]. It modulates autophagy activity and tau accumulation, thus may influence the severity of Alzheimer's disease (AD) [, ]. PICALM is required for erythroid maturation and transferrin internalisation in mice []. PICALM deficiency in mice results in impaired hematopoiesis, anemia, abnormal iron metabolism, growth defects, and shortened life span. It plays a key role in iron homeostasis and cell proliferation [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Scotland PB
Year: 2012
Journal: PLoS One
Title: The PICALM protein plays a key role in iron homeostasis and cell proliferation.
Volume: 7
Issue: 8
Pages: e44252
Publication
First Author: Suzuki M
Year: 2012
Journal: PLoS One
Title: The clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice.
Volume: 7
Issue: 2
Pages: e31854
Gene
Type: gene
Organism: Homo sapiens
Publication  
First Author: Moreau K
Year: 2014
Journal: Nat Commun
Title: PICALM modulates autophagy activity and tau accumulation.
Volume: 5
Pages: 4998
Publication
First Author: Xu W
Year: 2015
Journal: Mol Neurobiol
Title: The Role of PICALM in Alzheimer's Disease.
Volume: 52
Issue: 1
Pages: 399-413
Publication
First Author: Zhao Z
Year: 2015
Journal: Nat Neurosci
Title: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.
Volume: 18
Issue: 7
Pages: 978-87
Publication
First Author: Ishikawa Y
Year: 2015
Journal: Haematologica
Title: Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology.
Volume: 100
Issue: 4
Pages: 439-51
Publication
First Author: Klebig ML
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Mutations in the clathrin-assembly gene Picalm are responsible for the hematopoietic and iron metabolism abnormalities in fit1 mice.
Volume: 100
Issue: 14
Pages: 8360-5
Publication
First Author: Ando K
Year: 2013
Journal: Acta Neuropathol
Title: Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer's brains.
Volume: 125
Issue: 6
Pages: 861-78
Protein
Organism: Mus musculus
Length: 404  
Fragment?: true
Publication
First Author: Maritzen T
Year: 2012
Journal: Biol Cell
Title: Turning CALM into excitement: AP180 and CALM in endocytosis and disease.
Volume: 104
Issue: 10
Pages: 588-602
Protein
Organism: Mus musculus
Length: 660  
Fragment?: false
Protein
Organism: Mus musculus
Length: 531  
Fragment?: true
Protein
Organism: Mus musculus
Length: 674  
Fragment?: true
Protein
Organism: Mus musculus
Length: 85  
Fragment?: true
Protein
Organism: Mus musculus
Length: 597  
Fragment?: false
Gene
Type: gene
Organism: Rattus norvegicus
Publication
First Author: Kanatsu K
Year: 2016
Journal: Hum Mol Genet
Title: Partial loss of CALM function reduces Aβ42 production and amyloid deposition in vivo.
Volume: 25
Issue: 18
Pages: 3988-3997
Publication
First Author: Xiao Q
Year: 2012
Journal: J Biol Chem
Title: Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis.
Volume: 287
Issue: 25
Pages: 21279-89
Publication
First Author: Grizenkova J
Year: 2010
Journal: PLoS One
Title: The retinoic acid receptor beta (Rarb) region of Mmu14 is associated with prion disease incubation time in mouse.
Volume: 5
Issue: 12
Pages: e15019
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Potter MD
Year: 1997
Journal: Blood
Title: Mutations in the murine fitness 1 gene result in defective hematopoiesis.
Volume: 90
Issue: 5
Pages: 1850-7
Publication  
First Author: Kanatsu K
Year: 2014
Journal: Nat Commun
Title: Decreased CALM expression reduces Aβ42 to total Aβ ratio through clathrin-mediated endocytosis of γ-secretase.
Volume: 5
Pages: 3386
Publication
First Author: Schultze AE
Year: 1999
Journal: Lab Anim Sci
Title: Radiographic, histologic, and cytologic lesions associated with mutations in the fitness1(4226SB) locus of mice.
Volume: 49
Issue: 3
Pages: 260-8
Publication
First Author: Schultze AE
Year: 1997
Journal: Comp Haematol Int
Title: Alterations in growth, haematopoiesis and serum chemistry profiles in fitness 1(4226SB) mutant mice.
Volume: 7
Issue: 3
Pages: 143-151
Publication
First Author: Schultze AE
Year: 1998
Journal: Comp Haematol Int
Title: Alterations in serum and tissue iron profiles associated with mutations in the fitness1(4226SB) locus of mice.
Volume: 8
Issue: 2
Pages: 72-76
Publication
First Author: Petralia RS
Year: 2013
Journal: Neuromolecular Med
Title: Reduction of AP180 and CALM produces defects in synaptic vesicle size and density.
Volume: 15
Issue: 1
Pages: 49-60
Publication
First Author: Bushlin I
Year: 2008
Journal: J Neurosci
Title: Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons.
Volume: 28
Issue: 41
Pages: 10257-71
Publication
First Author: Harel A
Year: 2008
Journal: Traffic
Title: Evidence for CALM in directing VAMP2 trafficking.
Volume: 9
Issue: 3
Pages: 417-29
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5660010
Age: postnatal
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3759128
Assay Type: RT-PCR
Annotation Date: 2007-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:3759277
Age: embryonic day 18.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3759128
Assay Type: RT-PCR
Annotation Date: 2007-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737326
Stage: TS26
Assay Id: MGI:3759277
Age: embryonic day 18.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5660010
Age: postnatal
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5660010
Age: postnatal
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1860128
Stage: TS28
Assay Id: MGI:5660010
Age: postnatal
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:5660012
Age: embryonic day 12.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:5660012
Age: embryonic day 12.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:5660012
Age: embryonic day 12.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:5660012
Age: embryonic day 12.5
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:5660012
Age: embryonic day 12.5
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:5660012
Age: embryonic day 12.5
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5660010
Age: postnatal
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:5660010
Age: postnatal
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5659955
Assay Type: Western blot
Annotation Date: 2015-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5660010
Age: postnatal
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5659955
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Pattern: Punctate
Stage: TS21
Assay Id: MGI:5660014
Age: embryonic day 13.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5659955
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:5660014
Age: embryonic day 13.5
Detected: false
Specimen Num: 2
Publication    
First Author: Klebig ML
Year: 2003
Journal: GenBank Submission
Title: Mus musculus phosphatidylinositol-binding clathrin assembly protein (Picalm) mRNA, complete cds
Pages: AY206701
Publication  
First Author: Gimber N
Year: 2015
Journal: Nat Commun
Title: Diffusional spread and confinement of newly exocytosed synaptic vesicle proteins.
Volume: 6
Pages: 8392
Publication
First Author: Holdener BC
Year: 1995
Journal: Genomics
Title: Physical localization of eed: a region of mouse chromosome 7 required for gastrulation.
Volume: 27
Issue: 3
Pages: 447-56
Publication
First Author: Rinchik EM
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: A strategy for fine-structure functional analysis of a 6- to 11-centimorgan region of mouse chromosome 7 by high-efficiency mutagenesis.
Volume: 87
Issue: 3
Pages: 896-900
Publication
First Author: Potter MD
Year: 1995
Journal: Mamm Genome
Title: Genetic and physical mapping of the fitness 1 (fit1) locus within the Fes-Hbb region of mouse chromosome 7.
Volume: 6
Issue: 2
Pages: 70-5
Publication
First Author: Rinchik EM
Year: 1999
Journal: Genetics
Title: N-ethyl-N-nitrosourea mutagenesis of a 6- to 11-cM subregion of the Fah-Hbb interval of mouse chromosome 7: Completed testing of 4557 gametes and deletion mapping and complementation analysis of 31 mutations.
Volume: 152
Issue: 1
Pages: 373-83
Publication  
First Author: Schwab KR
Year: 2007
Journal: BMC Biol
Title: Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development.
Volume: 5
Pages: 15
Publication      
First Author: Oak Ridge National Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from the Oak Ridge National Laboratory Mutant Mouse Database (ORNL), Oak Ridge, TN
Publication
First Author: Schlesinger J
Year: 2011
Journal: PLoS Genet
Title: The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs.
Volume: 7
Issue: 2
Pages: e1001313
Publication
First Author: Choo HJ
Year: 2016
Journal: Stem Cells
Title: Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import.
Volume: 34
Issue: 11
Pages: 2784-2797
Publication
First Author: Nakano Y
Year: 2019
Journal: Cell Rep
Title: Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.
Volume: 27
Issue: 3
Pages: 860-871.e8
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database