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Search results 1 to 100 out of 808 for Pik3r1

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Type Details Score
Gene
5295 | PIK3R1
Type: gene
Organism: human
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Gene
461836 | PIK3R1
Type: gene
Organism: chimpanzee
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Gene
487235 | PIK3R1
Type: gene
Organism: dog, domestic
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Gene
282307 | PIK3R1
Type: gene
Organism: cattle
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Gene
427171 | PIK3R1
Type: gene
Organism: chicken
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Gene
557176 | pik3r1
Type: gene
Organism: zebrafish
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Gene
698996 | PIK3R1
Type: gene
Organism: macaque, rhesus
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Gene
100486835 | pik3r1
Type: gene
Organism: frog, western clawed
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Gene
25513 | Pik3r1
Type: gene
Organism: rat
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Protein Coding Gene
MGI:97583 | Pik3r1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
36943234 | J:340835
 
First Author: Nguyen T
Year: 2023
Journal: J Exp Med
Title: Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2.
Volume: 220
Issue: 6
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Publication
28292967 | J:246241
First Author: Kuo T
Year: 2017
Journal: Diabetes
Title: Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis.
Volume: 66
Issue: 6
Pages: 1601-1610
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Publication
22698915 | J:208529
First Author: McCurdy CE
Year: 2012
Journal: Diabetes
Title: Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice.
Volume: 61
Issue: 10
Pages: 2495-505
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Publication
33567340 | J:305235
   
First Author: Chen TC
Year: 2021
Journal: J Biol Chem
Title: The role of striated muscle Pik3r1 in glucose and protein metabolism following chronic glucocorticoid exposure.
Pages: 100395
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Publication
27157990 | J:233829
First Author: Cohran V
Year: 2016
Journal: Am J Pathol
Title: Epithelial PIK3R1 (p85) and TP53 Regulate Survivin Expression during Adaptation to Ileocecal Resection.
Volume: 186
Issue: 7
Pages: 1837-46
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191081
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pik3r1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191081
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pik3r1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191081
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pik3r1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191081
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pik3r1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191081
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pik3r1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191081
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pik3r1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6180639
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191081
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pik3r1
Detected: true
Specimen Num: 7
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Protein
Q99LY6
Organism: Mus musculus/domesticus
Length: 25  
Fragment?: true
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Publication
14673165 | J:87598
First Author: Chen D
Year: 2004
Journal: Mol Cell Biol
Title: p50alpha/p55alpha phosphoinositide 3-kinase knockout mice exhibit enhanced insulin sensitivity.
Volume: 24
Issue: 1
Pages: 320-9
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Publication
28630349 | J:244500
First Author: Thorpe LM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α.
Volume: 114
Issue: 27
Pages: 7095-7100
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Publication
20530665 | J:161603
First Author: Taniguchi CM
Year: 2010
Journal: Cancer Res
Title: The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.
Volume: 70
Issue: 13
Pages: 5305-15
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Publication
11781359 | J:73714
First Author: Mauvais-Jarvis F
Year: 2002
Journal: J Clin Invest
Title: Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes.
Volume: 109
Issue: 1
Pages: 141-9
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Publication
14976048 | J:90971
First Author: Kharas MG
Year: 2004
Journal: Blood
Title: Phosphoinositide 3-kinase signaling is essential for ABL oncogene-mediated transformation of B-lineage cells.
Volume: 103
Issue: 11
Pages: 4268-75
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Publication
21109194 | J:168115
First Author: Kaneko K
Year: 2010
Journal: Cell Metab
Title: Class IA phosphatidylinositol 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms.
Volume: 12
Issue: 6
Pages: 619-32
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Publication
16679292 | J:129647
First Author: Taniguchi CM
Year: 2006
Journal: Cell Metab
Title: Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta.
Volume: 3
Issue: 5
Pages: 343-53
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Publication
21730346 | J:181401
First Author: Ivanovic I
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Phosphoinositide 3-kinase signaling in retinal rod photoreceptors.
Volume: 52
Issue: 9
Pages: 6355-62
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Publication
26974159 | J:234657
First Author: Winnay JN
Year: 2016
Journal: J Clin Invest
Title: PI3-kinase mutation linked to insulin and growth factor resistance in vivo.
Volume: 126
Issue: 4
Pages: 1401-12
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Publication
11062485 | J:65523
First Author: Fruman DA
Year: 2000
Journal: Nat Genet
Title: Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha.
Volume: 26
Issue: 3
Pages: 379-82
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Publication
11784871 | J:125968
First Author: Ueki K
Year: 2002
Journal: Mol Cell Biol
Title: Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival.
Volume: 22
Issue: 3
Pages: 965-77
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Publication
19705443 | J:152699
First Author: Mouta-Bellum C
Year: 2009
Journal: Dev Dyn
Title: Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha.
Volume: 238
Issue: 10
Pages: 2670-9
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Publication
29724723 | J:263499
First Author: Solheim MH
Year: 2018
Journal: Diabetes
Title: Mice Carrying a Dominant-Negative Human PI3K Mutation Are Protected From Obesity and Hepatic Steatosis but Not Diabetes.
Volume: 67
Issue: 7
Pages: 1297-1309
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Publication
18704194 | J:140852
First Author: Kharas MG
Year: 2008
Journal: J Clin Invest
Title: Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.
Volume: 118
Issue: 9
Pages: 3038-50
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Publication
27708159 | J:236520
First Author: Zhang Z
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.
Volume: 113
Issue: 42
Pages: E6418-E6426
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Protein Coding Gene
MGP_CAROLIEiJ_G0018852 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020897 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020848 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020823 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020848 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020637 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97583 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021282 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020156 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020599 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020723 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020705 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020797 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020733 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021321 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019909 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020214 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015924 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019731 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1849460 | J:17845
First Author: Escobedo JA
Year: 1991
Journal: Cell
Title: cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF beta-receptor.
Volume: 65
Issue: 1
Pages: 75-82
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Publication
8921377 | J:35800
First Author: Fruman DA
Year: 1996
Journal: Genomics
Title: Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85 alpha gene.
Volume: 37
Issue: 1
Pages: 113-21
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Publication
17475862 | J:146117
First Author: Verkoczy L
Year: 2007
Journal: J Immunol
Title: Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection.
Volume: 178
Issue: 10
Pages: 6332-41
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Publication
- | J:254890
     
First Author: SoRelle J
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for anubis
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Publication
19541766 | J:157340
First Author: Acosta-Martínez M
Year: 2009
Journal: Endocrinology
Title: Male-biased effects of gonadotropin-releasing hormone neuron-specific deletion of the phosphoinositide 3-kinase regulatory subunit p85alpha on the reproductive axis.
Volume: 150
Issue: 9
Pages: 4203-12
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Publication
26565021 | J:230936
First Author: Goretsky T
Year: 2016
Journal: J Biol Chem
Title: A Cytosolic Multiprotein Complex Containing p85α Is Required for β-Catenin Activation in Colitis and Colitis-associated Cancer.
Volume: 291
Issue: 8
Pages: 4166-77
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Publication
- | J:254892
     
First Author: Zhong X
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Rocket
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Publication
- | J:272853
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for astro_boy.
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Publication
28632845 | J:257051
First Author: Solheim MH
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Iris Malformation and Anterior Segment Dysgenesis in Mice and Humans With a Mutation in PI 3-Kinase.
Volume: 58
Issue: 7
Pages: 3100-3106
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Publication
11850627 | J:74995
First Author: Fukao T
Year: 2002
Journal: Nat Immunol
Title: Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice.
Volume: 3
Issue: 3
Pages: 295-304
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Publication
22238586 | J:184151
First Author: Krishnan S
Year: 2012
Journal: PLoS One
Title: Class I(A) PI3Kinase regulatory subunit, p85α, mediates mast cell development through regulation of growth and survival related genes.
Volume: 7
Issue: 1
Pages: e28979
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Publication
22297723 | J:190782
First Author: Ma P
Year: 2012
Journal: Leukemia
Title: Role of intracellular tyrosines in activating KIT-induced myeloproliferative disease.
Volume: 26
Issue: 7
Pages: 1499-1506
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Publication
11756327 | J:107165
First Author: Eto K
Year: 2002
Journal: Diabetes
Title: Phosphatidylinositol 3-kinase suppresses glucose-stimulated insulin secretion by affecting post-cytosolic [Ca(2+)] elevation signals.
Volume: 51
Issue: 1
Pages: 87-97
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Publication
12649157 | J:110764
First Author: Watanabe N
Year: 2003
Journal: Blood
Title: Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation.
Volume: 102
Issue: 2
Pages: 541-8
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Publication
19176357 | J:148128
First Author: Aoki K
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Role of the liver in glucose homeostasis in PI 3-kinase p85alpha-deficient mice.
Volume: 296
Issue: 4
Pages: E842-53
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Publication
18809581 | J:142822
First Author: Munugalavadla V
Year: 2008
Journal: Mol Cell Biol
Title: The p85alpha subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration.
Volume: 28
Issue: 23
Pages: 7182-98
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Publication
21324896 | J:171139
First Author: Wu X
Year: 2011
Journal: J Biol Chem
Title: p85alpha regulates osteoblast differentiation by cross-talking with the MAPK pathway.
Volume: 286
Issue: 15
Pages: 13512-21
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Publication
15331535 | J:92073
First Author: Terauchi Y
Year: 2004
Journal: Diabetes
Title: Increased serum leptin protects from adiposity despite the increased glucose uptake in white adipose tissue in mice lacking p85alpha phosphoinositide 3-kinase.
Volume: 53
Issue: 9
Pages: 2261-70
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Publication
15769893 | J:107453
First Author: Munugalavadla V
Year: 2005
Journal: Blood
Title: p85alpha subunit of class IA PI-3 kinase is crucial for macrophage growth and migration.
Volume: 106
Issue: 1
Pages: 103-9
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Publication
28733636 | J:253698
First Author: Hayashi S
Year: 2017
Journal: Sci Rep
Title: PI3K p85α Subunit-deficient Macrophages Protect Mice from Acute Colitis due to the Enhancement of IL-10 Production.
Volume: 7
Issue: 1
Pages: 6187
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Publication
12429725 | J:124450
First Author: Yasui K
Year: 2002
Journal: J Leukoc Biol
Title: Granulocyte macrophage-colony stimulating factor delays neutrophil apoptosis and primes its function through Ia-type phosphoinositide 3-kinase.
Volume: 72
Issue: 5
Pages: 1020-6
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Publication
16670329 | J:131759
First Author: Yu Y
Year: 2006
Journal: J Immunol
Title: TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression.
Volume: 176
Issue: 10
Pages: 6194-201
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Publication
17324588 | J:123234
First Author: Zhu W
Year: 2007
Journal: Mol Cell Neurosci
Title: Phosphoinositide-3-kinase and mitogen activated protein kinase signaling pathways mediate acute NGF sensitization of TRPV1.
Volume: 34
Issue: 4
Pages: 689-700
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Publication
18303010 | J:133522
First Author: Doi T
Year: 2008
Journal: Int Immunol
Title: PI3K is a negative regulator of IgE production.
Volume: 20
Issue: 4
Pages: 499-508
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Publication
16166093 | J:102897
First Author: Barbour LA
Year: 2005
Journal: J Biol Chem
Title: Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess.
Volume: 280
Issue: 45
Pages: 37489-94
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Publication
10681597 | J:60675
First Author: Lu-Kuo JM
Year: 2000
Journal: J Biol Chem
Title: Impaired kit- but not FcepsilonRI-initiated mast cell activation in the absence of phosphoinositide 3-kinase p85alpha gene products.
Volume: 275
Issue: 8
Pages: 6022-9
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Publication
12623844 | J:106371
First Author: Huddleston H
Year: 2003
Journal: Blood
Title: Functional p85alpha gene is required for normal murine fetal erythropoiesis.
Volume: 102
Issue: 1
Pages: 142-5
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Publication
16043515 | J:114734
First Author: Luo J
Year: 2005
Journal: J Cell Biol
Title: The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex.
Volume: 170
Issue: 3
Pages: 455-64
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Publication
11038173 | J:292595
First Author: Jiménez C
Year: 2000
Journal: J Cell Biol
Title: Role of the PI3K regulatory subunit in the control of actin organization and cell migration.
Volume: 151
Issue: 2
Pages: 249-62
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Publication
7504175 | J:327402
First Author: Sun XJ
Year: 1993
Journal: Mol Cell Biol
Title: Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1.
Volume: 13
Issue: 12
Pages: 7418-28
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Publication
20598684 | J:200509
First Author: Dubielecka PM
Year: 2010
Journal: FEBS Lett
Title: Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.
Volume: 584
Issue: 15
Pages: 3279-86
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Publication
10783143 | J:61807
First Author: Borlado LR
Year: 2000
Journal: FASEB J
Title: Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo.
Volume: 14
Issue: 7
Pages: 895-903
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Publication
8054357 | J:19783
First Author: Fry MJ
Year: 1994
Journal: Biochim Biophys Acta
Title: Structure, regulation and function of phosphoinositide 3-kinases.
Volume: 1226
Issue: 3
Pages: 237-68
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Publication
7698770 | J:21917
First Author: Hoyle J
Year: 1994
Journal: Genomics
Title: The gene that encodes the phosphatidylinositol-3 kinase regulatory subunit (p85 alpha) maps to chromosome 13 in the mouse.
Volume: 24
Issue: 2
Pages: 400-2
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Publication
8706703 | J:34363
First Author: Ricort JM
Year: 1996
Journal: Eur J Biochem
Title: Different effects of insulin and platelet-derived growth factor on phosphatidylinositol 3-kinase at the subcellular level in 3T3-L1 adipocytes. A possible explanation for their specific effects on glucose transport.
Volume: 239
Issue: 1
Pages: 17-22
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Publication
8754810 | J:34390
First Author: Klippel A
Year: 1996
Journal: Mol Cell Biol
Title: Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways.
Volume: 16
Issue: 8
Pages: 4117-27
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Publication
14688354 | J:87549
First Author: Williams DL
Year: 2004
Journal: J Immunol
Title: Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis.
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Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: A novel signaling pathway for beta-adrenergic receptor-mediated activation of phosphoinositide 3-kinase in H9c2 cardiomyocytes.
Volume: 293
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First Author: Lee JY
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of PI3K binding to activators by serine phosphorylation of PI3K regulatory subunit p85alpha Src homology-2 domains.
Volume: 108
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Year: 2012
Journal: FEBS Lett
Title: miR-376a suppresses proliferation and induces apoptosis in hepatocellular carcinoma.
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Year: 2018
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Title: P85 regulates neuronal migration through affecting neuronal morphology during mouse corticogenesis.
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Year: 2018
Journal: Nat Commun
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Title: Genetic disruption of the PI3K regulatory subunits, p85α, p55α, and p50α, normalizes mutant PTPN11-induced hypersensitivity to GM-CSF.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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