|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 770 for Pik3r1

<< First    < Previous  |  Next >    Last >>
0.038s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Kuo T
Year: 2017
Journal: Diabetes
Title: Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis.
Volume: 66
Issue: 6
Pages: 1601-1610
Publication
First Author: McCurdy CE
Year: 2012
Journal: Diabetes
Title: Attenuated Pik3r1 expression prevents insulin resistance and adipose tissue macrophage accumulation in diet-induced obese mice.
Volume: 61
Issue: 10
Pages: 2495-505
Publication
First Author: Cohran V
Year: 2016
Journal: Am J Pathol
Title: Epithelial PIK3R1 (p85) and TP53 Regulate Survivin Expression during Adaptation to Ileocecal Resection.
Volume: 186
Issue: 7
Pages: 1837-46
Protein
Organism: Mus musculus
Length: 25  
Fragment?: true
Publication
First Author: Chen D
Year: 2004
Journal: Mol Cell Biol
Title: p50alpha/p55alpha phosphoinositide 3-kinase knockout mice exhibit enhanced insulin sensitivity.
Volume: 24
Issue: 1
Pages: 320-9
Publication
First Author: Thorpe LM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α.
Volume: 114
Issue: 27
Pages: 7095-7100
Publication
First Author: Taniguchi CM
Year: 2010
Journal: Cancer Res
Title: The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.
Volume: 70
Issue: 13
Pages: 5305-15
Publication
First Author: Mauvais-Jarvis F
Year: 2002
Journal: J Clin Invest
Title: Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes.
Volume: 109
Issue: 1
Pages: 141-9
Publication
First Author: Kharas MG
Year: 2004
Journal: Blood
Title: Phosphoinositide 3-kinase signaling is essential for ABL oncogene-mediated transformation of B-lineage cells.
Volume: 103
Issue: 11
Pages: 4268-75
Publication
First Author: Ueki K
Year: 2002
Journal: Mol Cell Biol
Title: Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival.
Volume: 22
Issue: 3
Pages: 965-77
Publication
First Author: Taniguchi CM
Year: 2006
Journal: Cell Metab
Title: Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta.
Volume: 3
Issue: 5
Pages: 343-53
Publication
First Author: Kaneko K
Year: 2010
Journal: Cell Metab
Title: Class IA phosphatidylinositol 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms.
Volume: 12
Issue: 6
Pages: 619-32
Publication
First Author: Winnay JN
Year: 2016
Journal: J Clin Invest
Title: PI3-kinase mutation linked to insulin and growth factor resistance in vivo.
Volume: 126
Issue: 4
Pages: 1401-12
Publication
First Author: Fruman DA
Year: 2000
Journal: Nat Genet
Title: Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha.
Volume: 26
Issue: 3
Pages: 379-82
Publication
First Author: Ivanovic I
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Phosphoinositide 3-kinase signaling in retinal rod photoreceptors.
Volume: 52
Issue: 9
Pages: 6355-62
Publication
First Author: Mouta-Bellum C
Year: 2009
Journal: Dev Dyn
Title: Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha.
Volume: 238
Issue: 10
Pages: 2670-9
Publication
First Author: Solheim MH
Year: 2018
Journal: Diabetes
Title: Mice Carrying a Dominant-Negative Human PI3K Mutation Are Protected From Obesity and Hepatic Steatosis but Not Diabetes.
Volume: 67
Issue: 7
Pages: 1297-1309
Publication
First Author: Kharas MG
Year: 2008
Journal: J Clin Invest
Title: Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.
Volume: 118
Issue: 9
Pages: 3038-50
Publication
First Author: Zhang Z
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice.
Volume: 113
Issue: 42
Pages: E6418-E6426
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Escobedo JA
Year: 1991
Journal: Cell
Title: cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF beta-receptor.
Volume: 65
Issue: 1
Pages: 75-82
Publication
First Author: Fruman DA
Year: 1996
Journal: Genomics
Title: Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85 alpha gene.
Volume: 37
Issue: 1
Pages: 113-21
Publication
First Author: Verkoczy L
Year: 2007
Journal: J Immunol
Title: Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection.
Volume: 178
Issue: 10
Pages: 6332-41
Publication
First Author: Solheim MH
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Iris Malformation and Anterior Segment Dysgenesis in Mice and Humans With a Mutation in PI 3-Kinase.
Volume: 58
Issue: 7
Pages: 3100-3106
Publication      
First Author: Zhong X
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Rocket
Publication      
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for astro_boy.
Publication      
First Author: SoRelle J
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for anubis
Publication
First Author: Terauchi Y
Year: 2004
Journal: Diabetes
Title: Increased serum leptin protects from adiposity despite the increased glucose uptake in white adipose tissue in mice lacking p85alpha phosphoinositide 3-kinase.
Volume: 53
Issue: 9
Pages: 2261-70
Publication
First Author: Yu Y
Year: 2006
Journal: J Immunol
Title: TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression.
Volume: 176
Issue: 10
Pages: 6194-201
Publication
First Author: Munugalavadla V
Year: 2008
Journal: Mol Cell Biol
Title: The p85alpha subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration.
Volume: 28
Issue: 23
Pages: 7182-98
Publication
First Author: Eto K
Year: 2002
Journal: Diabetes
Title: Phosphatidylinositol 3-kinase suppresses glucose-stimulated insulin secretion by affecting post-cytosolic [Ca(2+)] elevation signals.
Volume: 51
Issue: 1
Pages: 87-97
Publication
First Author: Hayashi S
Year: 2017
Journal: Sci Rep
Title: PI3K p85α Subunit-deficient Macrophages Protect Mice from Acute Colitis due to the Enhancement of IL-10 Production.
Volume: 7
Issue: 1
Pages: 6187
Publication
First Author: Aoki K
Year: 2009
Journal: Am J Physiol Endocrinol Metab
Title: Role of the liver in glucose homeostasis in PI 3-kinase p85alpha-deficient mice.
Volume: 296
Issue: 4
Pages: E842-53
Publication
First Author: Yasui K
Year: 2002
Journal: J Leukoc Biol
Title: Granulocyte macrophage-colony stimulating factor delays neutrophil apoptosis and primes its function through Ia-type phosphoinositide 3-kinase.
Volume: 72
Issue: 5
Pages: 1020-6
Publication
First Author: Krishnan S
Year: 2012
Journal: PLoS One
Title: Class I(A) PI3Kinase regulatory subunit, p85α, mediates mast cell development through regulation of growth and survival related genes.
Volume: 7
Issue: 1
Pages: e28979
Publication
First Author: Munugalavadla V
Year: 2005
Journal: Blood
Title: p85alpha subunit of class IA PI-3 kinase is crucial for macrophage growth and migration.
Volume: 106
Issue: 1
Pages: 103-9
Publication
First Author: Doi T
Year: 2008
Journal: Int Immunol
Title: PI3K is a negative regulator of IgE production.
Volume: 20
Issue: 4
Pages: 499-508
Publication
First Author: Watanabe N
Year: 2003
Journal: Blood
Title: Functional phenotype of phosphoinositide 3-kinase p85alpha-null platelets characterized by an impaired response to GP VI stimulation.
Volume: 102
Issue: 2
Pages: 541-8
Publication
First Author: Wu X
Year: 2011
Journal: J Biol Chem
Title: p85alpha regulates osteoblast differentiation by cross-talking with the MAPK pathway.
Volume: 286
Issue: 15
Pages: 13512-21
Publication
First Author: Fukao T
Year: 2002
Journal: Nat Immunol
Title: Selective loss of gastrointestinal mast cells and impaired immunity in PI3K-deficient mice.
Volume: 3
Issue: 3
Pages: 295-304
Publication
First Author: Zhu W
Year: 2007
Journal: Mol Cell Neurosci
Title: Phosphoinositide-3-kinase and mitogen activated protein kinase signaling pathways mediate acute NGF sensitization of TRPV1.
Volume: 34
Issue: 4
Pages: 689-700
Publication
First Author: Ma P
Year: 2012
Journal: Leukemia
Title: Role of intracellular tyrosines in activating KIT-induced myeloproliferative disease.
Volume: 26
Issue: 7
Pages: 1499-1506
Publication
First Author: Lu-Kuo JM
Year: 2000
Journal: J Biol Chem
Title: Impaired kit- but not FcepsilonRI-initiated mast cell activation in the absence of phosphoinositide 3-kinase p85alpha gene products.
Volume: 275
Issue: 8
Pages: 6022-9
Publication
First Author: Huddleston H
Year: 2003
Journal: Blood
Title: Functional p85alpha gene is required for normal murine fetal erythropoiesis.
Volume: 102
Issue: 1
Pages: 142-5
Publication
First Author: Barbour LA
Year: 2005
Journal: J Biol Chem
Title: Increased P85alpha is a potent negative regulator of skeletal muscle insulin signaling and induces in vivo insulin resistance associated with growth hormone excess.
Volume: 280
Issue: 45
Pages: 37489-94
Publication
First Author: Acosta-Martínez M
Year: 2009
Journal: Endocrinology
Title: Male-biased effects of gonadotropin-releasing hormone neuron-specific deletion of the phosphoinositide 3-kinase regulatory subunit p85alpha on the reproductive axis.
Volume: 150
Issue: 9
Pages: 4203-12
Publication
First Author: Goretsky T
Year: 2016
Journal: J Biol Chem
Title: A Cytosolic Multiprotein Complex Containing p85α Is Required for β-Catenin Activation in Colitis and Colitis-associated Cancer.
Volume: 291
Issue: 8
Pages: 4166-77
Publication
First Author: Dubielecka PM
Year: 2010
Journal: FEBS Lett
Title: Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.
Volume: 584
Issue: 15
Pages: 3279-86
Publication
First Author: Luo J
Year: 2005
Journal: J Cell Biol
Title: The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex.
Volume: 170
Issue: 3
Pages: 455-64
Publication
First Author: Jiménez C
Year: 2000
Journal: J Cell Biol
Title: Role of the PI3K regulatory subunit in the control of actin organization and cell migration.
Volume: 151
Issue: 2
Pages: 249-62
Publication
First Author: Borlado LR
Year: 2000
Journal: FASEB J
Title: Increased phosphoinositide 3-kinase activity induces a lymphoproliferative disorder and contributes to tumor generation in vivo.
Volume: 14
Issue: 7
Pages: 895-903
Publication
First Author: Fry MJ
Year: 1994
Journal: Biochim Biophys Acta
Title: Structure, regulation and function of phosphoinositide 3-kinases.
Volume: 1226
Issue: 3
Pages: 237-68
Publication
First Author: Hoyle J
Year: 1994
Journal: Genomics
Title: The gene that encodes the phosphatidylinositol-3 kinase regulatory subunit (p85 alpha) maps to chromosome 13 in the mouse.
Volume: 24
Issue: 2
Pages: 400-2
Publication
First Author: Ricort JM
Year: 1996
Journal: Eur J Biochem
Title: Different effects of insulin and platelet-derived growth factor on phosphatidylinositol 3-kinase at the subcellular level in 3T3-L1 adipocytes. A possible explanation for their specific effects on glucose transport.
Volume: 239
Issue: 1
Pages: 17-22
Publication
First Author: Klippel A
Year: 1996
Journal: Mol Cell Biol
Title: Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways.
Volume: 16
Issue: 8
Pages: 4117-27
Publication
First Author: Williams DL
Year: 2004
Journal: J Immunol
Title: Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis.
Volume: 172
Issue: 1
Pages: 449-56
Publication
First Author: Yano N
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: A novel signaling pathway for beta-adrenergic receptor-mediated activation of phosphoinositide 3-kinase in H9c2 cardiomyocytes.
Volume: 293
Issue: 1
Pages: H385-93
Publication
First Author: Lee JY
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of PI3K binding to activators by serine phosphorylation of PI3K regulatory subunit p85alpha Src homology-2 domains.
Volume: 108
Issue: 34
Pages: 14157-62
Publication
First Author: Zheng Y
Year: 2012
Journal: FEBS Lett
Title: miR-376a suppresses proliferation and induces apoptosis in hepatocellular carcinoma.
Volume: 586
Issue: 16
Pages: 2396-403
Publication
First Author: Cheng X
Year: 2018
Journal: Cell Tissue Res
Title: P85 regulates neuronal migration through affecting neuronal morphology during mouse corticogenesis.
Volume: 372
Issue: 1
Pages: 23-31
Publication
First Author: Corallino S
Year: 2018
Journal: Nat Commun
Title: A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration.
Volume: 9
Issue: 1
Pages: 1475
GXD Expression      
Probe: MGI:2662820
Assay Type: Northern blot
Annotation Date: 2003-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2663859
Age: postnatal day 4
Detected: true
Specimen Num: 16
GXD Expression        
Probe: MGI:2662820
Assay Type: Northern blot
Annotation Date: 2003-06-26
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2663859
Age: postnatal day 30
Specimen Num: 25
GXD Expression      
Probe: MGI:2662820
Assay Type: Northern blot
Annotation Date: 2003-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2663859
Age: postnatal day 4
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:2662820
Assay Type: Northern blot
Annotation Date: 2003-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2663859
Age: postnatal day 30
Detected: true
Specimen Num: 20
GXD Expression      
Probe: MGI:2662820
Assay Type: Northern blot
Annotation Date: 2003-06-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640521
Stage: TS21
Assay Id: MGI:2663859
Age: embryonic day 13.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5288952
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289315
Age: embryonic day 2.0
Detected: false
Specimen Num: 13
GXD Expression      
Probe: MGI:5288952
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289315
Age: embryonic day 2.0
Detected: false
Specimen Num: 14
GXD Expression      
Probe: MGI:5288952
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289315
Age: embryonic day 2.0
Detected: false
Specimen Num: 15
GXD Expression      
Probe: MGI:5288952
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289315
Age: embryonic day 2.0
Detected: false
Specimen Num: 16
GXD Expression      
Probe: MGI:5288952
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289315
Age: embryonic day 2.0
Detected: false
Specimen Num: 17
GXD Expression      
Probe: MGI:5288952
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289315
Age: embryonic day 2.0
Detected: false
Specimen Num: 18
GXD Expression      
Probe: MGI:5288952
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289315
Age: embryonic day 2.0
Detected: false
Specimen Num: 19
GXD Expression      
Probe: MGI:5288952
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289315
Age: embryonic day 2.0
Detected: false
Specimen Num: 20
GXD Expression      
Probe: MGI:5288952
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289315
Age: embryonic day 2.0
Detected: false
Specimen Num: 21
GXD Expression      
Probe: MGI:5288952
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289315
Age: embryonic day 2.0
Detected: false
Specimen Num: 22
GXD Expression      
Probe: MGI:5288952
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289315
Age: embryonic day 2.0
Detected: false
Specimen Num: 23
GXD Expression      
Probe: MGI:5288952
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289315
Age: embryonic day 2.0
Detected: false
Specimen Num: 24