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Search results 1 to 100 out of 557 for Pink1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Sliter DA
Year: 2018
Journal: Nature
Title: Parkin and PINK1 mitigate STING-induced inflammation.
Volume: 561
Issue: 7722
Pages: 258-262
Publication
First Author: Koyano F
Year: 2014
Journal: Nature
Title: Ubiquitin is phosphorylated by PINK1 to activate parkin.
Volume: 510
Issue: 7503
Pages: 162-6
Publication
First Author: Han H
Year: 2020
Journal: EMBO Rep
Title: PINK1 phosphorylates Drp1S616 to regulate mitophagy-independent mitochondrial dynamics.
Volume: 21
Issue: 8
Pages: e48686
Publication
First Author: Lee Y
Year: 2017
Journal: Cell Rep
Title: PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival.
Volume: 18
Issue: 4
Pages: 918-932
Publication
First Author: Oliveras-Salvá M
Year: 2014
Journal: Neurobiol Aging
Title: Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice.
Volume: 35
Issue: 11
Pages: 2625-2636
Publication
First Author: Wang X
Year: 2014
Journal: PLoS One
Title: BAG5 protects against mitochondrial oxidative damage through regulating PINK1 degradation.
Volume: 9
Issue: 1
Pages: e86276
Publication
First Author: Soman SK
Year: 2021
Journal: J Neurosci Res
Title: Cleaved PINK1 induces neuronal plasticity through PKA-mediated BDNF functional regulation.
Volume: 99
Issue: 9
Pages: 2134-2155
Publication
First Author: Siddall HK
Year: 2013
Journal: PLoS One
Title: Loss of PINK1 increases the heart's vulnerability to ischemia-reperfusion injury.
Volume: 8
Issue: 4
Pages: e62400
Publication
First Author: Bueno M
Year: 2015
Journal: J Clin Invest
Title: PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis.
Volume: 125
Issue: 2
Pages: 521-38
Publication  
First Author: Mei X
Year: 2023
Journal: Mol Immunol
Title: Deficiency of Pink1 promotes the differentiation of Th1 cells.
Volume: 160
Pages: 23-31
Publication
First Author: Choi HK
Year: 2015
Journal: Hum Mol Genet
Title: PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death.
Volume: 24
Issue: 4
Pages: 1127-41
Publication
First Author: Chiba M
Year: 2009
Journal: Cytogenet Genome Res
Title: Existence of Pink1 antisense RNAs in mouse and their localization.
Volume: 126
Issue: 3
Pages: 259-70
Publication
First Author: Um JW
Year: 2009
Journal: Mol Cell Neurosci
Title: Molecular interaction between parkin and PINK1 in mammalian neuronal cells.
Volume: 40
Issue: 4
Pages: 421-32
Publication
First Author: Matheoud D
Year: 2016
Journal: Cell
Title: Parkinson's Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation.
Volume: 166
Issue: 2
Pages: 314-327
Publication
First Author: Matsui H
Year: 2013
Journal: Hum Mol Genet
Title: PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates.
Volume: 22
Issue: 12
Pages: 2423-34
Publication  
First Author: Furlong RM
Year: 2019
Journal: J Cell Sci
Title: The Parkinson's disease gene PINK1 activates Akt via PINK1 kinase-dependent regulation of the phospholipid PI(3,4,5)P3.
Volume: 132
Issue: 20
Publication
First Author: Morais VA
Year: 2014
Journal: Science
Title: PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling.
Volume: 344
Issue: 6180
Pages: 203-7
Publication  
First Author: Cossu D
Year: 2022
Journal: Front Immunol
Title: Age related immune modulation of experimental autoimmune encephalomyelitis in PINK1 knockout mice.
Volume: 13
Pages: 1036680
Publication
First Author: Walsh TG
Year: 2018
Journal: Sci Rep
Title: Loss of the mitochondrial kinase PINK1 does not alter platelet function.
Volume: 8
Issue: 1
Pages: 14377
Publication  
First Author: Zhi L
Year: 2019
Journal: Neurobiol Aging
Title: Loss of PINK1 causes age-dependent decrease of dopamine release and mitochondrial dysfunction.
Volume: 75
Pages: 1-10
Publication
First Author: Dagda RK
Year: 2014
Journal: J Neurochem
Title: Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through protein kinase A.
Volume: 128
Issue: 6
Pages: 864-77
Publication  
First Author: Requejo-Aguilar R
Year: 2014
Journal: Nat Commun
Title: PINK1 deficiency sustains cell proliferation by reprogramming glucose metabolism through HIF1.
Volume: 5
Pages: 4514
Publication
First Author: Oh CK
Year: 2017
Journal: Cell Rep
Title: S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models.
Volume: 21
Issue: 8
Pages: 2171-2182
Publication
First Author: Akundi RS
Year: 2012
Journal: Neurobiol Dis
Title: PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis.
Volume: 45
Issue: 1
Pages: 469-78
Publication  
First Author: Madeo G
Year: 2016
Journal: Neuropharmacology
Title: Dopamine-dependent CB1 receptor dysfunction at corticostriatal synapses in homozygous PINK1 knockout mice.
Volume: 101
Pages: 460-70
Publication
First Author: Kawajiri S
Year: 2010
Journal: FEBS Lett
Title: PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy.
Volume: 584
Issue: 6
Pages: 1073-9
Publication
First Author: McWilliams TG
Year: 2018
Journal: Cell Metab
Title: Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand.
Volume: 27
Issue: 2
Pages: 439-449.e5
Publication
First Author: Gehrke S
Year: 2015
Journal: Cell Metab
Title: PINK1 and Parkin control localized translation of respiratory chain component mRNAs on mitochondria outer membrane.
Volume: 21
Issue: 1
Pages: 95-108
Publication
First Author: Bus C
Year: 2020
Journal: iScience
Title: Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors.
Volume: 23
Issue: 12
Pages: 101797
Publication  
First Author: Lopez-Fabuel I
Year: 2017
Journal: Neurochem Int
Title: Mitochondrial respiratory chain disorganization in Parkinson's disease-relevant PINK1 and DJ1 mutants.
Volume: 109
Pages: 101-105
Publication
First Author: Li C
Year: 2018
Journal: Dev Cell
Title: PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism.
Volume: 46
Issue: 4
Pages: 441-455.e8
Publication
First Author: Gautier CA
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress.
Volume: 105
Issue: 32
Pages: 11364-9
Publication
First Author: Morais VA
Year: 2009
Journal: EMBO Mol Med
Title: Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function.
Volume: 1
Issue: 2
Pages: 99-111
Publication
First Author: Ellis GI
Year: 2013
Journal: Eur J Immunol
Title: Mitochondrial and cytosolic roles of PINK1 shape induced regulatory T-cell development and function.
Volume: 43
Issue: 12
Pages: 3355-60
Publication
First Author: Sun L
Year: 2018
Journal: Sci Rep
Title: Lack of PINK1 alters glia innate immune responses and enhances inflammation-induced, nitric oxide-mediated neuron death.
Volume: 8
Issue: 1
Pages: 383
Publication
First Author: Wood-Kaczmar A
Year: 2008
Journal: PLoS One
Title: PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons.
Volume: 3
Issue: 6
Pages: e2455
Publication
First Author: Heeman B
Year: 2011
Journal: J Cell Sci
Title: Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance.
Volume: 124
Issue: Pt 7
Pages: 1115-25
Publication
First Author: Ashrafi G
Year: 2014
Journal: J Cell Biol
Title: Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin.
Volume: 206
Issue: 5
Pages: 655-70
Publication
First Author: Huang T
Year: 2020
Journal: Aging (Albany NY)
Title: Fbxo7 and Pink1 play a reciprocal role in regulating their protein levels.
Volume: 13
Issue: 1
Pages: 77-88
Publication
First Author: Zhang Y
Year: 2014
Journal: J Immunol
Title: Endothelial PINK1 mediates the protective effects of NLRP3 deficiency during lethal oxidant injury.
Volume: 192
Issue: 11
Pages: 5296-304
Publication
First Author: Wan H
Year: 2018
Journal: Cell Death Differ
Title: Analysis of neuronal phosphoproteome reveals PINK1 regulation of BAD function and cell death.
Volume: 25
Issue: 5
Pages: 904-917
Publication
First Author: Choi J
Year: 2013
Journal: Biochem Biophys Res Commun
Title: A novel PGC-1α isoform in brain localizes to mitochondria and associates with PINK1 and VDAC.
Volume: 435
Issue: 4
Pages: 671-7
Publication
First Author: Yamada T
Year: 2019
Journal: Autophagy
Title: SQSTM1/p62 promotes mitochondrial ubiquitination independently of PINK1 and PRKN/parkin in mitophagy.
Volume: 15
Issue: 11
Pages: 2012-2018
Publication
First Author: Lin W
Year: 2014
Journal: J Neurosci
Title: Loss of PINK1 attenuates HIF-1α induction by preventing 4E-BP1-dependent switch in protein translation under hypoxia.
Volume: 34
Issue: 8
Pages: 3079-89
Publication  
First Author: Bueno M
Year: 2018
Journal: Aging Cell
Title: ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis.
Volume: 17
Issue: 2
Publication
First Author: Bueno M
Year: 2019
Journal: PLoS One
Title: PINK1 attenuates mtDNA release in alveolar epithelial cells and TLR9 mediated profibrotic responses.
Volume: 14
Issue: 6
Pages: e0218003
Publication  
First Author: Li J
Year: 2022
Journal: Front Cell Dev Biol
Title: Reciprocal Regulation of Mitofusin 2-Mediated Mitophagy and Mitochondrial Fusion by Different PINK1 Phosphorylation Events.
Volume: 10
Pages: 868465
Publication
First Author: Li J
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Mitochondrial DNA heteroplasmy rises in substantial nigra of aged PINK1 KO mice.
Volume: 521
Issue: 4
Pages: 1024-1029
Publication
First Author: Kubli DA
Year: 2015
Journal: PLoS One
Title: PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes.
Volume: 10
Issue: 6
Pages: e0130707
Publication
First Author: Zhang Y
Year: 2021
Journal: Am J Physiol Lung Cell Mol Physiol
Title: PINK1 mediates the protective effects of thyroid hormone T3 in hyperoxia-induced lung injury.
Volume: 320
Issue: 6
Pages: L1118-L1125
Publication
First Author: Gispert S
Year: 2015
Journal: Hum Mol Genet
Title: Potentiation of neurotoxicity in double-mutant mice with Pink1 ablation and A53T-SNCA overexpression.
Volume: 24
Issue: 4
Pages: 1061-76
Publication  
First Author: Imbriani P
Year: 2019
Journal: Int J Mol Sci
Title: Loss of Non-Apoptotic Role of Caspase-3 in the PINK1 Mouse Model of Parkinson's Disease.
Volume: 20
Issue: 14
Publication
First Author: Knippenberg S
Year: 2013
Journal: J Neuropathol Exp Neurol
Title: Altered expression of DJ-1 and PINK1 in sporadic ALS and in the SOD1(G93A) ALS mouse model.
Volume: 72
Issue: 11
Pages: 1052-61
Publication  
First Author: Docherty CK
Year: 2021
Journal: Int J Mol Sci
Title: An Inducible and Vascular Smooth Muscle Cell-Specific Pink1 Knockout Induces Mitochondrial Energetic Dysfunction during Atherogenesis.
Volume: 22
Issue: 18
Publication
First Author: Das Banerjee T
Year: 2017
Journal: J Neurochem
Title: PINK1 regulates mitochondrial trafficking in dendrites of cortical neurons through mitochondrial PKA.
Volume: 142
Issue: 4
Pages: 545-559
Publication
First Author: Wang HL
Year: 2011
Journal: Biochim Biophys Acta
Title: PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons.
Volume: 1812
Issue: 6
Pages: 674-84
Publication  
First Author: Key J
Year: 2020
Journal: Cells
Title: Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence.
Volume: 9
Issue: 10
Publication
First Author: Zhou H
Year: 2007
Journal: Int J Biol Sci
Title: Silencing of the Pink1 gene expression by conditional RNAi does not induce dopaminergic neuron death in mice.
Volume: 3
Issue: 4
Pages: 242-50
Publication
First Author: Amo T
Year: 2011
Journal: Neurobiol Dis
Title: Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects.
Volume: 41
Issue: 1
Pages: 111-8
Publication
First Author: Chen BB
Year: 2014
Journal: Cell Rep
Title: E3 ligase subunit Fbxo15 and PINK1 kinase regulate cardiolipin synthase 1 stability and mitochondrial function in pneumonia.
Volume: 7
Issue: 2
Pages: 476-87
Publication
First Author: Mei Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation.
Volume: 106
Issue: 13
Pages: 5153-8
Publication
First Author: Triplett JC
Year: 2015
Journal: J Neurochem
Title: Quantitative expression proteomics and phosphoproteomics profile of brain from PINK1 knockout mice: insights into mechanisms of familial Parkinson's disease.
Volume: 133
Issue: 5
Pages: 750-65
Publication
First Author: Ponia SS
Year: 2021
Journal: Cell Rep
Title: Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues.
Volume: 37
Issue: 4
Pages: 109888
Publication
First Author: d'Amora M
Year: 2011
Journal: J Chem Neuroanat
Title: Expression of PINK1 in the brain, eye and ear of mouse during embryonic development.
Volume: 41
Issue: 2
Pages: 73-85
Publication
First Author: Koyano F
Year: 2013
Journal: Genes Cells
Title: The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons.
Volume: 18
Issue: 8
Pages: 672-81
Publication
First Author: Yoo L
Year: 2018
Journal: J Biol Chem
Title: The ubiquitin E3 ligase CHIP promotes proteasomal degradation of the serine/threonine protein kinase PINK1 during staurosporine-induced cell death.
Volume: 293
Issue: 4
Pages: 1286-1297
Publication  
First Author: Sen NE
Year: 2016
Journal: Neurobiol Dis
Title: Search for SCA2 blood RNA biomarkers highlights Ataxin-2 as strong modifier of the mitochondrial factor PINK1 levels.
Volume: 96
Pages: 115-126
Publication  
First Author: Agnihotri SK
Year: 2019
Journal: Behav Brain Res
Title: PINK1 deficiency is associated with increased deficits of adult hippocampal neurogenesis and lowers the threshold for stress-induced depression in mice.
Volume: 363
Pages: 161-172
Publication
First Author: Sanchez G
Year: 2014
Journal: PLoS One
Title: Unaltered striatal dopamine release levels in young Parkin knockout, Pink1 knockout, DJ-1 knockout and LRRK2 R1441G transgenic mice.
Volume: 9
Issue: 4
Pages: e94826
Publication  
First Author: Choi I
Year: 2016
Journal: Mol Brain
Title: PINK1 expression increases during brain development and stem cell differentiation, and affects the development of GFAP-positive astrocytes.
Volume: 9
Pages: 5
Publication
First Author: Choi I
Year: 2013
Journal: Glia
Title: PINK1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced AKT and increased p38 MAPK activation, and downregulation of EGFR.
Volume: 61
Issue: 5
Pages: 800-12
Publication
First Author: Hang L
Year: 2019
Journal: Neuromolecular Med
Title: AMP Kinase Activation is Selectively Disrupted in the Ventral Midbrain of Mice Deficient in Parkin or PINK1 Expression.
Volume: 21
Issue: 1
Pages: 25-32
Publication
First Author: Kim SJ
Year: 2020
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Mitochondrial 8-oxoguanine DNA glycosylase mitigates alveolar epithelial cell PINK1 deficiency, mitochondrial DNA damage, apoptosis, and lung fibrosis.
Volume: 318
Issue: 5
Pages: L1084-L1096
Publication
First Author: Haque ME
Year: 2012
Journal: J Biol Chem
Title: Inactivation of Pink1 gene in vivo sensitizes dopamine-producing neurons to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and can be rescued by autosomal recessive Parkinson disease genes, Parkin or DJ-1.
Volume: 287
Issue: 27
Pages: 23162-70
Publication
First Author: Agnihotri SK
Year: 2017
Journal: FASEB J
Title: Loss of PINK1 leads to metabolic deficits in adult neural stem cells and impedes differentiation of newborn neurons in the mouse hippocampus.
Volume: 31
Issue: 7
Pages: 2839-2853
Publication
First Author: Martella G
Year: 2009
Journal: Exp Neurol
Title: Enhanced sensitivity to group II mGlu receptor activation at corticostriatal synapses in mice lacking the familial parkinsonism-linked genes PINK1 or Parkin.
Volume: 215
Issue: 2
Pages: 388-96
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Vos M
Year: 2017
Journal: J Cell Biol
Title: Cardiolipin promotes electron transport between ubiquinone and complex I to rescue PINK1 deficiency.
Volume: 216
Issue: 3
Pages: 695-708
Publication      
First Author: Kelm-Nelson CA
Year: 2017
Journal: Brain Res
Title: Characterization of early-onset motor deficits in the Pink1 -/- mouse model of Parkinson disease.
Publication
First Author: Wu Z
Year: 2013
Journal: Genes Dev
Title: Tricornered/NDR kinase signaling mediates PINK1-directed mitochondrial quality control and tissue maintenance.
Volume: 27
Issue: 2
Pages: 157-62
Publication  
First Author: Mu J
Year: 2020
Journal: J Mol Cell Cardiol
Title: BRD4 inhibition by JQ1 prevents high-fat diet-induced diabetic cardiomyopathy by activating PINK1/Parkin-mediated mitophagy in vivo.
Volume: 149
Pages: 1-14
Publication
First Author: Gandhi S
Year: 2009
Journal: Mol Cell
Title: PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death.
Volume: 33
Issue: 5
Pages: 627-38
Publication  
First Author: Amo T
Year: 2014
Journal: Neurosci Lett
Title: Detailed analysis of mitochondrial respiratory chain defects caused by loss of PINK1.
Volume: 580
Pages: 37-40
Publication
First Author: Ordureau A
Year: 2014
Journal: Mol Cell
Title: Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.
Volume: 56
Issue: 3
Pages: 360-75
Publication
First Author: Shim JH
Year: 2011
Journal: Mitochondrion
Title: The antioxidant Trolox helps recovery from the familial Parkinson's disease-specific mitochondrial deficits caused by PINK1- and DJ-1-deficiency in dopaminergic neuronal cells.
Volume: 11
Issue: 5
Pages: 707-15
Publication
First Author: Huang E
Year: 2017
Journal: Nat Commun
Title: PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress.
Volume: 8
Issue: 1
Pages: 1399
Publication  
First Author: Lu W
Year: 2014
Journal: Nat Commun
Title: Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder.
Volume: 5
Pages: 4930
Publication
First Author: Glasl L
Year: 2012
Journal: Exp Neurol
Title: Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb.
Volume: 235
Issue: 1
Pages: 214-27
Publication
First Author: Kitada T
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice.
Volume: 104
Issue: 27
Pages: 11441-6