Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Interaction Term |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of dsDNA Baculovirus proteins. It is required for the infectivity of the OBs or occlusion bodies. It is a structural protein of the ODV envelope required only in the first steps of per os larva infection, as viruses being produced in cells expressing the gene for this protein but not containing it in their genomes are able to produce successful infections. Baculoviruses are large DNA viruses that infect arthropods, mainly members of the order Lepidoptera. In their life cycle, they produce two kinds of particles, a budded, non-occluded virus (BV), which buds out of the infected cell and is responsible for the cell-to-cell transmission of the virus, and an occluded form, the occlusion body (OB), which is responsible for protecting the virus between encounters with larvae. A variable number of virions are included in the para-crystalline structure of the OB, mainly constituted by the virus-encoded polyhedrin protein; these virions are called occlusion body-derived virions or ODVs []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
PIR SuperFamily Classification Load vis PIR/UNIPROT |
Year: |
2005 |
|
Title: |
Protein SuperFamily Classification Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kikhno I |
Year: |
2002 |
Journal: |
J Gen Virol |
Title: |
Characterization of pif, a gene required for the per os infectivity of Spodoptera littoralis nucleopolyhedrovirus. |
Volume: |
83 |
Issue: |
Pt 12 |
Pages: |
3013-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Licciulli S |
Year: |
2010 |
Journal: |
Leukemia |
Title: |
Pirin downregulation is a feature of AML and leads to impairment of terminal myeloid differentiation. |
Volume: |
24 |
Issue: |
2 |
Pages: |
429-37 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Wendler WM |
Year: |
1997 |
Journal: |
J Biol Chem |
Title: |
Identification of pirin, a novel highly conserved nuclear protein. |
Volume: |
272 |
Issue: |
13 |
Pages: |
8482-9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1733904 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-04-19 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7621767 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1733904 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-04-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7621767 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1733904 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-04-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7621767 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Supplementary table 2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cox BJ |
Year: |
2010 |
Journal: |
Genome Res |
Title: |
Phenotypic annotation of the mouse X chromosome. |
Volume: |
20 |
Issue: |
8 |
Pages: |
1154-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cox BJ |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Phenotypic annotation of the mouse X chromosome |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration |
Year: |
2001 |
|
Title: |
LocusLink Collaboration |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GO Central curators, GOA curators, Rhea curators |
Year: |
2020 |
|
Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yokoyama S |
Year: |
2009 |
Journal: |
Dev Cell |
Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
Volume: |
17 |
Issue: |
6 |
Pages: |
836-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators, MGI curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Mouse Synonym Curation |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
Journal: |
Database Download |
Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6295186 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-05-01 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3276728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6295360 |
Age: |
postnatal week 10-14 |
|
Note: |
Expression is present in neurons. |
Specimen Label: |
S2b Pir |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
Data Source |
URL: |
http://pir.georgetown.edu/cgi-bin/ipcSF?id=<> |
|
•
•
•
•
•
|
Publication |
First Author: |
Toh-e A |
Year: |
1993 |
Journal: |
Yeast |
Title: |
Three yeast genes, PIR1, PIR2 and PIR3, containing internal tandem repeats, are related to each other, and PIR1 and PIR2 are required for tolerance to heat shock. |
Volume: |
9 |
Issue: |
5 |
Pages: |
481-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mrsă V |
Year: |
1997 |
Journal: |
Yeast |
Title: |
Specific labelling of cell wall proteins by biotinylation. Identification of four covalently linked O-mannosylated proteins of Saccharomyces cerevisiae. |
Volume: |
13 |
Issue: |
12 |
Pages: |
1145-54 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Repeat |
Description: |
A number of yeast cell wall glycoproteins are characterised by the presence oftandem repeats of a region of 18 to 19 residues [, ]. |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6295186 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-05-01 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3276728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6295360 |
Age: |
postnatal week 10-14 |
|
Note: |
Expression is present in neurons; none co-express GAD65/67. |
Specimen Label: |
S3a GAD65/67 + Crh - Pir |
Detected: |
true |
Specimen Num: |
20 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6295186 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-05-01 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3276728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6295360 |
Age: |
postnatal week 10-14 |
|
Note: |
Expression is present in neurons; the majority co-express Vglut1. |
Specimen Label: |
S3a Vglut1 + Crh - Pir |
Detected: |
true |
Specimen Num: |
21 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6295186 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-05-01 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3276728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6295360 |
Age: |
postnatal week 10-14 |
|
Note: |
Expression is present in neurons; the majority co-express Camk2a. |
Specimen Label: |
S3a Camk2a + Crh - Pir |
Detected: |
true |
Specimen Num: |
23 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6295187 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-05-06 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3276728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6295983 |
Age: |
postnatal week 10-14 |
|
Note: |
Expression is present in neurons. |
Specimen Label: |
S3a Camk2a + Crh - Pir |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6295179 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-05-06 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3276728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6295980 |
Age: |
postnatal week 10-14 |
|
Note: |
Expression is present in neurons. |
Specimen Label: |
S3a GAD65/67 + Crh - Pir |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6295180 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-05-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3276728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6296657 |
Age: |
postnatal week 10-14 |
|
Note: |
Expression is present in neurons. |
Specimen Label: |
S3a GAD65/67 + Crh - Pir |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6295184 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-05-06 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3276728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6295986 |
Age: |
postnatal week 10-14 |
|
Note: |
Expression is present in neurons. |
Specimen Label: |
S3a Vglut2 + Crh - Pir |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6295181 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-05-06 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3276728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6295984 |
Age: |
postnatal week 10-14 |
|
Note: |
Expression is present in neurons. |
Specimen Label: |
S3a Vglut1 + Crh - Pir |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6295186 |
Assay Type: |
RNA in situ |
Annotation Date: |
2019-05-01 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3276728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6295360 |
Age: |
postnatal week 10-14 |
|
Note: |
Expression is present in neurons; a subset co-express Vglut2. |
Specimen Label: |
S3a Vglut2 + Crh - Pir |
Detected: |
true |
Specimen Num: |
22 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
290
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Malek M |
Year: |
2017 |
Journal: |
Mol Cell |
Title: |
PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K. |
Volume: |
68 |
Issue: |
3 |
Pages: |
566-580.e10 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the SH2 domain of Grb14. The Grb7 (growth factor receptor-bound 7) family includes Grb7, Grb10, and Grb14. These are adapter proteins mediating signal transduction from multiple cell surface receptors to diverse downstream pathways. They are composed of an N-terminal proline-rich domain, a Ras Associating-like (RA) domain, a Pleckstrin Homology (PH) domain, a PIR (phosphorylated insulin receptor interacting region) domain (also known as the family-specific BPS region), and a C-terminal SH2 domain []. Grb14 binds to various receptor tyrosine kinases (RTKs) under ligand induction. This interaction involves the SH2 and PIR domains []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The Grb7 (growth factor receptor-bound 7) family includes Grb7, Grb10, and Grb14. These are adapter proteins mediating signal transduction from multiple cell surface receptors to diverse downstream pathways. They are composed of an N-terminal proline-rich domain, a Ras Associating-like (RA) domain, a Pleckstrin Homology (PH) domain, a PIR (phosphorylated insulin receptor interacting region) domain (also known as the family-specific BPS region), and a C-terminal SH2 domain []. Grb14 binds to various receptor tyrosine kinases (RTKs) under ligand induction. This interaction involves the SH2 and PIR domains []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Cariou B |
Year: |
2004 |
Journal: |
Front Biosci |
Title: |
Regulation and functional roles of Grb14. |
Volume: |
9 |
|
Pages: |
1626-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Masuda K |
Year: |
2005 |
Journal: |
EMBO J |
Title: |
Prethymic T-cell development defined by the expression of paired immunoglobulin-like receptors. |
Volume: |
24 |
Issue: |
23 |
Pages: |
4052-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dennis G Jr |
Year: |
1999 |
Journal: |
J Immunol |
Title: |
Characterization of paired Ig-like receptors in rats. |
Volume: |
163 |
Issue: |
12 |
Pages: |
6371-7 |
|
•
•
•
•
•
|