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Search results 1 to 100 out of 2473 for Pitx2

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Hits by Strain

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Waite MR
Year: 2011
Journal: Dev Dyn
Title: GABAergic and glutamatergic identities of developing midbrain Pitx2 neurons.
Volume: 240
Issue: 2
Pages: 333-46
Publication
First Author: Ai D
Year: 2006
Journal: Dev Biol
Title: Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium.
Volume: 296
Issue: 2
Pages: 437-49
Publication
First Author: Shiratori H
Year: 2006
Journal: Development
Title: Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs.
Volume: 133
Issue: 15
Pages: 3015-25
Publication
First Author: Rozani I
Year: 2019
Journal: Sci Rep
Title: Pitx2 cholinergic interneurons are the source of C bouton synapses on brainstem motor neurons.
Volume: 9
Issue: 1
Pages: 4936
Publication  
First Author: Waite MR
Year: 2013
Journal: Mol Cell Neurosci
Title: Pleiotropic and isoform-specific functions for Pitx2 in superior colliculus and hypothalamic neuronal development.
Volume: 52
Pages: 128-39
Publication
First Author: Li X
Year: 2013
Journal: PLoS One
Title: Dact2 represses PITX2 transcriptional activation and cell proliferation through Wnt/beta-catenin signaling during odontogenesis.
Volume: 8
Issue: 1
Pages: e54868
Publication
First Author: Sun Z
Year: 2016
Journal: Development
Title: Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal.
Volume: 143
Issue: 22
Pages: 4115-4126
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Skidmore JM
Year: 2008
Journal: Mol Cell Neurosci
Title: Cre fate mapping reveals lineage specific defects in neuronal migration with loss of Pitx2 function in the developing mouse hypothalamus and subthalamic nucleus.
Volume: 37
Issue: 4
Pages: 696-707
Publication
First Author: Liu W
Year: 2003
Journal: Development
Title: Genetic dissection of Pitx2 in craniofacial development uncovers new functions in branchial arch morphogenesis, late aspects of tooth morphogenesis and cell migration.
Volume: 130
Issue: 25
Pages: 6375-85
Publication
First Author: Schweizer N
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Limiting glutamate transmission in a Vglut2-expressing subpopulation of the subthalamic nucleus is sufficient to cause hyperlocomotion.
Volume: 111
Issue: 21
Pages: 7837-42
Publication
First Author: Liu C
Year: 2002
Journal: Development
Title: Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions.
Volume: 129
Issue: 21
Pages: 5081-91
Publication
First Author: Zagoraiou L
Year: 2009
Journal: Neuron
Title: A cluster of cholinergic premotor interneurons modulates mouse locomotor activity.
Volume: 64
Issue: 5
Pages: 645-62
Publication
First Author: Cao H
Year: 2013
Journal: Development
Title: The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation.
Volume: 140
Issue: 16
Pages: 3348-59
Publication
First Author: Vue TY
Year: 2007
Journal: J Comp Neurol
Title: Characterization of progenitor domains in the developing mouse thalamus.
Volume: 505
Issue: 1
Pages: 73-91
Publication
First Author: Waite MR
Year: 2012
Journal: Mol Cell Neurosci
Title: Distinct populations of GABAergic neurons in mouse rhombomere 1 express but do not require the homeodomain transcription factor PITX2.
Volume: 49
Issue: 1
Pages: 32-43
Publication  
First Author: Nishioka T
Year: 2020
Journal: Front Syst Neurosci
Title: Chemogenetic Suppression of the Subthalamic Nucleus Induces Attentional Deficits and Impulsive Action in a Five-Choice Serial Reaction Time Task in Mice.
Volume: 14
Pages: 38
Publication
First Author: Viereckel T
Year: 2018
Journal: J Neurochem
Title: Validated multi-step approach for in vivo recording and analysis of optogenetically evoked glutamate in the mouse globus pallidus.
Volume: 145
Issue: 2
Pages: 125-138
Publication
First Author: Cao H
Year: 2010
Journal: J Dent Res
Title: MicroRNAs play a critical role in tooth development.
Volume: 89
Issue: 8
Pages: 779-84
Publication  
First Author: Schweizer N
Year: 2016
Journal: eNeuro
Title: Reduced Vglut2/Slc17a6 Gene Expression Levels throughout the Mouse Subthalamic Nucleus Cause Cell Loss and Structural Disorganization Followed by Increased Motor Activity and Decreased Sugar Consumption.
Volume: 3
Issue: 5
Publication
First Author: Chu EY
Year: 2016
Journal: J Dent Res
Title: Full Spectrum of Postnatal Tooth Phenotypes in a Novel Irf6 Cleft Lip Model.
Volume: 95
Issue: 11
Pages: 1265-73
Publication
First Author: Tamasas B
Year: 2017
Journal: J Dent Res
Title: Massively Increased Caries Susceptibility in an Irf6 Cleft Lip/Palate Model.
Volume: 96
Issue: 3
Pages: 315-322
Publication
First Author: Zampieri N
Year: 2014
Journal: Neuron
Title: Mapping sensory circuits by anterograde transsynaptic transfer of recombinant rabies virus.
Volume: 81
Issue: 4
Pages: 766-78
Publication
First Author: Shiratori H
Year: 2014
Journal: Dev Biol
Title: Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb.
Volume: 395
Issue: 2
Pages: 331-41
Publication
First Author: Masullo L
Year: 2019
Journal: Curr Biol
Title: Genetically Defined Functional Modules for Spatial Orienting in the Mouse Superior Colliculus.
Volume: 29
Issue: 17
Pages: 2892-2904.e8
Publication
First Author: Liu P
Year: 2010
Journal: Dev Dyn
Title: Lmx1b is required for murine trabecular meshwork formation and for maintenance of corneal transparency.
Volume: 239
Issue: 8
Pages: 2161-71
Publication
First Author: Zhang Z
Year: 2010
Journal: J Biol Chem
Title: MicroRNAs regulate pituitary development, and microRNA 26b specifically targets lymphoid enhancer factor 1 (Lef-1), which modulates pituitary transcription factor 1 (Pit-1) expression.
Volume: 285
Issue: 45
Pages: 34718-28
Publication
First Author: Mommersteeg MT
Year: 2007
Journal: Circ Res
Title: Pitx2c and Nkx2-5 are required for the formation and identity of the pulmonary myocardium.
Volume: 101
Issue: 9
Pages: 902-9
Publication
First Author: Mortensen AH
Year: 2015
Journal: Hum Mol Genet
Title: Deletion of OTX2 in neural ectoderm delays anterior pituitary development.
Volume: 24
Issue: 4
Pages: 939-53
Allele
Name: paired-like homeodomain transcription factor 2; targeted mutation 4, James F Martin
Allele Type: Targeted
Attribute String: Recombinase
Publication categories: ProxyCollection
Allele
Name: transgene insertion 1, YiPeng Chen
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Publication
First Author: Chang CN
Year: 2019
Journal: Dev Biol
Title: Requirement of Pitx2 for skeletal muscle homeostasis.
Volume: 445
Issue: 1
Pages: 90-102
Publication
First Author: Hjalt TA
Year: 2000
Journal: Dev Dyn
Title: The Pitx2 protein in mouse development.
Volume: 218
Issue: 1
Pages: 195-200
Publication
First Author: Holmberg J
Year: 2004
Journal: Am J Pathol
Title: PITX2 gain-of-function in Rieger syndrome eye model.
Volume: 165
Issue: 5
Pages: 1633-41
Publication
First Author: Ryan AK
Year: 1998
Journal: Nature
Title: Pitx2 determines left-right asymmetry of internal organs in vertebrates.
Volume: 394
Issue: 6693
Pages: 545-51
Genotype
Symbol: Hand2/Hand2 Tg(Pitx2-cre)1Ych/?
Background: involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gsk3b/Gsk3b Tg(Pitx2-cre)1Ych/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Sclafani AM
Year: 2006
Journal: Genesis
Title: Nestin-Cre mediated deletion of Pitx2 in the mouse.
Volume: 44
Issue: 7
Pages: 336-44
Publication
First Author: Zhang HZ
Year: 2006
Journal: Exp Hematol
Title: Hematopoiesis following disruption of the Pitx2 homeodomain gene.
Volume: 34
Issue: 2
Pages: 167-78
Publication
First Author: Dong F
Year: 2006
Journal: Development
Title: Pitx2 promotes development of splanchnic mesoderm-derived branchiomeric muscle.
Volume: 133
Issue: 24
Pages: 4891-9
Publication
First Author: Gage PJ
Year: 1999
Journal: Development
Title: Dosage requirement of Pitx2 for development of multiple organs.
Volume: 126
Issue: 20
Pages: 4643-51
Publication
First Author: Hayashi M
Year: 2008
Journal: J Biol Chem
Title: Pitx2 prevents osteoblastic transdifferentiation of myoblasts by bone morphogenetic proteins.
Volume: 283
Issue: 1
Pages: 565-71
Publication
First Author: French CR
Year: 2014
Journal: J Clin Invest
Title: Mutation of FOXC1 and PITX2 induces cerebral small-vessel disease.
Volume: 124
Issue: 11
Pages: 4877-81
Publication
First Author: Marcil A
Year: 2003
Journal: Development
Title: Pitx1 and Pitx2 are required for development of hindlimb buds.
Volume: 130
Issue: 1
Pages: 45-55
Publication
First Author: Zacharias AL
Year: 2011
Journal: Dev Biol
Title: Pitx2 is an upstream activator of extraocular myogenesis and survival.
Volume: 349
Issue: 2
Pages: 395-405
Publication
First Author: Castinetti F
Year: 2011
Journal: Mol Endocrinol
Title: PITX2 AND PITX1 regulate thyrotroph function and response to hypothyroidism.
Volume: 25
Issue: 11
Pages: 1950-60
Publication  
First Author: Holmberg J
Year: 2008
Journal: BMC Dev Biol
Title: PITX2 gain-of-function induced defects in mouse forelimb development.
Volume: 8
Pages: 25
Publication
First Author: Amen M
Year: 2007
Journal: Mol Cell Biol
Title: PITX2 and beta-catenin interactions regulate Lef-1 isoform expression.
Volume: 27
Issue: 21
Pages: 7560-73
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450743
Age: embryonic day 12.5
Image: Pitx2 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Num: 2
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450743
Age: embryonic day 14.5
Image: Pitx2 - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Num: 3
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450743
Age: embryonic day 12.5
Image: Pitx2 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Num: 2
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450743
Age: embryonic day 14.5
Image: Pitx2 - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Num: 3
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450743
Age: embryonic day 12.5
Image: Pitx2 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Num: 2
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450743
Age: embryonic day 14.5
Image: Pitx2 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Num: 3
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450743
Age: embryonic day 12.5
Image: Pitx2 - E12.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Num: 2
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450743
Age: embryonic day 16.5
Image: Pitx2 - E16.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Num: 4
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450743
Age: embryonic day 11.5
Image: Pitx2 - E11.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex and the ganglionic eminences.
Specimen Num: 1
GXD Expression
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3271820
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450743
Age: embryonic day 12.5
Image: Pitx2 - E12.5
Note: There is very strong staining in the mantle zone of the mam and supramam zones. Staining is either absent or ubiquitous in the mantle zone of the premam zone and the TT.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3271822
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450743
Age: embryonic day 14.5
Image: Pitx2 - E14.5
Note: There is very strong staining in the mantle zone of the mam and supramam zones. Staining is either absent or ubiquitous in the mantle zone of the premam zone and the TT.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3271824
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450743
Age: embryonic day 16.5
Image: Pitx2 - E16.5
Note: There is very strong staining in the mantle zone of the mam and supramam zones. Staining is either absent or ubiquitous in the mantle zone of the premam zone.
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1690819
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450743
Age: embryonic day 11.5
Image: Pitx2 - E11.5
Note: There is very strong staining in the VZ of the mam & supramam zone. Staining is either absent or ubiquitous in the VZ of the dorsal thalamus, prethalamus, dorsal & ventral POAs, PVH, VMH & ARH nuclei, the AVH, anterior & posterior IDs, premam zone & TT.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450743
Age: embryonic day 12.5
Image: Pitx2 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Num: 2
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450743
Age: embryonic day 14.5
Image: Pitx2 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Num: 3
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450743
Age: embryonic day 16.5
Image: Pitx2 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Num: 4
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450743
Age: embryonic day 11.5
Image: Pitx2 - E11.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
Specimen Num: 1
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450743
Age: embryonic day 12.5
Image: Pitx2 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Num: 2
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450743
Age: embryonic day 14.5
Image: Pitx2 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Num: 3
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450743
Age: embryonic day 16.5
Image: Pitx2 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Num: 4
GXD Expression
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3271020
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450743
Age: embryonic day 12.5
Image: Pitx2 - E12.5
Note: There is very strong staining in the ventricular zone of the mam and supramam zone. Staining is either absent or ubiquitous in the ventricular zone of the premam zone and the TT.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3271022
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450743
Age: embryonic day 14.5
Image: Pitx2 - E14.5
Note: There is very strong staining in the ventricular zone of the mam and supramam zones. Staining is either absent or ubiquitous in the ventricular zone of the premam zone and the TT.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:3271024
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450743
Age: embryonic day 16.5
Image: Pitx2 - E16.5
Note: There is very strong staining in the ventricular zone of the mam and supramam zones. Staining is either absent or ubiquitous in the ventricular zone of the premam zone.
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450743
Age: embryonic day 12.5
Image: Pitx2 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Num: 2
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450743
Age: embryonic day 14.5
Image: Pitx2 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Num: 3
GXD Expression
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1690619
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450743
Age: embryonic day 11.5
Image: Pitx2 - E11.5
Note: Staining is very strong in the MZ of the mam & supramam zones & strong in prethalamus. Staining is either absent or ubiquitous in the MZ of the dorsal thalamus, dorsal & ventral POAs, PVH, VMH & ARH nuclei, AVH, anterior & posterior IDs, premam zone & TT.
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754122
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450743
Age: embryonic day 14.5
Image: Pitx2 - E14.5
Note: There is very strong staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754124
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450743
Age: embryonic day 16.5
Image: Pitx2 - E16.5
Note: There is strong staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus.
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3694945
Assay Type: RNA in situ
Annotation Date: 2007-02-08
Strength: Absent
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:3696046
Age: embryonic day 12.0
Image: 3 Pitx2 XX+/+
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:3694945
Assay Type: RNA in situ
Annotation Date: 2007-02-08
Strength: Present
Sex: Female
Emaps: EMAPS:1796220
Pattern: Single cells
Stage: TS20
Assay Id: MGI:3696046
Age: embryonic day 12.0
Image: 3 Pitx2 XX-/-
Note: Expression is in scattered cells.
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450743
Age: embryonic day 16.5
Image: Pitx2 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Num: 4
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450743
Age: embryonic day 16.5
Image: Pitx2 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Num: 4
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450743
Age: embryonic day 16.5
Image: Pitx2 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Num: 4
GXD Expression
Probe: MGI:3694945
Assay Type: RNA in situ
Annotation Date: 2007-02-08
Strength: Present
Sex: Male
Emaps: EMAPS:2909820
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:3696046
Age: embryonic day 12.0
Image: 3 Pitx2 XY+/+
Note: Expression is in the testis cords.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450743
Age: embryonic day 14.5
Image: Pitx2 - E14.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Num: 3
GXD Expression  
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450743
Age: embryonic day 16.5
Image: Pitx2 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Num: 4
GXD Expression
Probe: MGI:3254902
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754120
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450743
Age: embryonic day 12.5
Image: Pitx2 - E12.5
Note: There is very strong staining in the mantle zone of the dorsal thalamus. Staining is either absent or ubiquitous in the mantle zone of the prethalamus.
Detected: true
Specimen Num: 2
Publication
First Author: Piedra ME
Year: 1998
Journal: Cell
Title: Pitx2 participates in the late phase of the pathway controlling left-right asymmetry.
Volume: 94
Issue: 3
Pages: 319-24
Publication
First Author: Charles MA
Year: 2008
Journal: Genesis
Title: Pitx2 deletion in pituitary gonadotropes is compatible with gonadal development, puberty, and fertility.
Volume: 46
Issue: 10
Pages: 507-14
Publication
First Author: Logan M
Year: 1998
Journal: Cell
Title: The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals.
Volume: 94
Issue: 3
Pages: 307-17
Publication
First Author: Xiong W
Year: 2009
Journal: Dev Biol
Title: Hand2 is required in the epithelium for palatogenesis in mice.
Volume: 330
Issue: 1
Pages: 131-41
Publication
First Author: He F
Year: 2010
Journal: Dev Dyn
Title: Gsk3β is required in the epithelium for palatal elevation in mice.
Volume: 239
Issue: 12
Pages: 3235-46
Publication
First Author: Schweickert A
Year: 2000
Journal: Mech Dev
Title: Pitx2 isoforms: involvement of Pitx2c but not Pitx2a or Pitx2b in vertebrate left-right asymmetry.
Volume: 90
Issue: 1
Pages: 41-51
Publication
First Author: Lozano-Velasco E
Year: 2017
Journal: PLoS One
Title: Hyperthyroidism, but not hypertension, impairs PITX2 expression leading to Wnt-microRNA-ion channel remodeling.
Volume: 12
Issue: 12
Pages: e0188473
Publication
First Author: Lozano-Velasco E
Year: 2016
Journal: Cardiovasc Res
Title: Pitx2 impairs calcium handling in a dose-dependent manner by modulating Wnt signalling.
Volume: 109
Issue: 1
Pages: 55-66
Publication
First Author: L'honoré A
Year: 2014
Journal: Dev Cell
Title: Redox regulation by Pitx2 and Pitx3 is critical for fetal myogenesis.
Volume: 29
Issue: 4
Pages: 392-405
Publication
First Author: L'Honoré A
Year: 2007
Journal: Dev Biol
Title: Sequential expression and redundancy of Pitx2 and Pitx3 genes during muscle development.
Volume: 307
Issue: 2
Pages: 421-33
Publication
First Author: Nadadur RD
Year: 2016
Journal: Sci Transl Med
Title: Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm.
Volume: 8
Issue: 354
Pages: 354ra115