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Search results 1 to 100 out of 277 for Piwil1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Piwi proteins, together with their associated Piwi-interacting RNAs (piRNAs), are evolutionarily conserved in animals and play important roles in transposon silencing during gametogenesis []. Mammalian Piwi proteins include PIWIL1/Miwi, PIWIL2/Mili, PIWIL3 and PIWIL4/Miwi2.PIWI-like 1 (PIWIL1) is essential for the transition of round spermatid into elongated spermatid [], and also plays a role in the polarisation and radial migration of newborn neurons in the developing cerebral cortex [].
Publication  
First Author: Zhao PP
Year: 2015
Journal: Mol Brain
Title: Novel function of PIWIL1 in neuronal polarization and migration via regulation of microtubule-associated proteins.
Volume: 8
Pages: 39
Publication
First Author: Deng W
Year: 2002
Journal: Dev Cell
Title: miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis.
Volume: 2
Issue: 6
Pages: 819-30
Publication
First Author: Sutherland JM
Year: 2018
Journal: J Cell Physiol
Title: RNA binding protein Musashi-2 regulates PIWIL1 and TBX1 in mouse spermatogenesis.
Volume: 233
Issue: 4
Pages: 3262-3273
Publication
First Author: Wu Y
Year: 2018
Journal: Biol Reprod
Title: Domain-functional analyses of PIWIL1 and PABPC1 indicate their synergistic roles in protein translation via 3'-UTRs of meiotic mRNAs.
Volume: 99
Issue: 4
Pages: 773-788
Protein
Organism: Mus musculus/domesticus
Length: 862  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: true
Publication  
First Author: Thomson T
Year: 2009
Journal: Annu Rev Cell Dev Biol
Title: The biogenesis and function of PIWI proteins and piRNAs: progress and prospect.
Volume: 25
Pages: 355-76
Publication
First Author: Dai P
Year: 2019
Journal: Cell
Title: A Translation-Activating Function of MIWI/piRNA during Mouse Spermiogenesis.
Volume: 179
Issue: 7
Pages: 1566-1581.e16
Publication
First Author: Wei C
Year: 2023
Journal: PLoS Genet
Title: MIWI N-terminal RG motif promotes efficient pachytene piRNA production and spermatogenesis independent of LINE1 transposon silencing.
Volume: 19
Issue: 11
Pages: e1011031
Publication
First Author: Kotaja N
Year: 2006
Journal: J Cell Sci
Title: Interplay of PIWI/Argonaute protein MIWI and kinesin KIF17b in chromatoid bodies of male germ cells.
Volume: 119
Issue: Pt 13
Pages: 2819-25
Publication
First Author: Grivna ST
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis.
Volume: 103
Issue: 36
Pages: 13415-20
Publication
First Author: Vourekas A
Year: 2012
Journal: Nat Struct Mol Biol
Title: Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis.
Volume: 19
Issue: 8
Pages: 773-81
Publication
First Author: Zhang H
Year: 2017
Journal: Reproduction
Title: KH-type splicing regulatory protein is a new component of chromatoid body.
Volume: 154
Issue: 6
Pages: 723-733
Publication
First Author: Özata DM
Year: 2020
Journal: Nat Ecol Evol
Title: Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans.
Volume: 4
Issue: 1
Pages: 156-168
Publication
First Author: Wasik KA
Year: 2015
Journal: Genes Dev
Title: RNF17 blocks promiscuous activity of PIWI proteins in mouse testes.
Volume: 29
Issue: 13
Pages: 1403-15
Publication
First Author: Kojima K
Year: 2009
Journal: Genes Cells
Title: Associations between PIWI proteins and TDRD1/MTR-1 are critical for integrated subcellular localization in murine male germ cells.
Volume: 14
Issue: 10
Pages: 1155-65
Publication
First Author: Liu K
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain.
Volume: 107
Issue: 43
Pages: 18398-403
Publication
First Author: Li XZ
Year: 2013
Journal: Mol Cell
Title: An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes.
Volume: 50
Issue: 1
Pages: 67-81
Publication
First Author: Beyret E
Year: 2011
Journal: Dev Biol
Title: Pinpointing the expression of piRNAs and function of the PIWI protein subfamily during spermatogenesis in the mouse.
Volume: 355
Issue: 2
Pages: 215-26
Publication
First Author: Watanabe T
Year: 2015
Journal: Genome Res
Title: Retrotransposons and pseudogenes regulate mRNAs and lncRNAs via the piRNA pathway in the germline.
Volume: 25
Issue: 3
Pages: 368-80
Publication
First Author: Gainetdinov I
Year: 2021
Journal: Mol Cell
Title: Terminal modification, sequence, length, and PIWI-protein identity determine piRNA stability.
Volume: 81
Issue: 23
Pages: 4826-4842.e8
Publication
First Author: Hsieh CL
Year: 2020
Journal: EMBO J
Title: MIWI prevents aneuploidy during meiosis by cleaving excess satellite RNA.
Volume: 39
Issue: 16
Pages: e103614
Publication
First Author: Xu M
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: MIWI-independent small RNAs (MSY-RNAs) bind to the RNA-binding protein, MSY2, in male germ cells.
Volume: 106
Issue: 30
Pages: 12371-6
Publication
First Author: Nolde MJ
Year: 2013
Journal: PLoS One
Title: Piwi genes are dispensable for normal hematopoiesis in mice.
Volume: 8
Issue: 8
Pages: e71950
Publication
First Author: Xu K
Year: 2014
Journal: Biol Reprod
Title: AKAP3 synthesis is mediated by RNA binding proteins and PKA signaling during mouse spermiogenesis.
Volume: 90
Issue: 6
Pages: 119
Publication
First Author: Cheng EC
Year: 2014
Journal: PLoS One
Title: PIWI proteins are dispensable for mouse somatic development and reprogramming of fibroblasts into pluripotent stem cells.
Volume: 9
Issue: 9
Pages: e97821
Publication
First Author: Ding D
Year: 2018
Journal: Nat Commun
Title: TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice.
Volume: 9
Issue: 1
Pages: 127
Publication
First Author: Vagin VV
Year: 2009
Journal: Genes Dev
Title: Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members.
Volume: 23
Issue: 15
Pages: 1749-62
Publication
First Author: Ding D
Year: 2019
Journal: Nucleic Acids Res
Title: Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis.
Volume: 47
Issue: 5
Pages: 2594-2608
Publication
First Author: Kabayama Y
Year: 2017
Journal: Nucleic Acids Res
Title: Roles of MIWI, MILI and PLD6 in small RNA regulation in mouse growing oocytes.
Volume: 45
Issue: 9
Pages: 5387-5398
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Grivna ST
Year: 2006
Journal: Genes Dev
Title: A novel class of small RNAs in mouse spermatogenic cells.
Volume: 20
Issue: 13
Pages: 1709-14
Publication
First Author: Girard A
Year: 2006
Journal: Nature
Title: A germline-specific class of small RNAs binds mammalian Piwi proteins.
Volume: 442
Issue: 7099
Pages: 199-202
Publication
First Author: Reuter M
Year: 2011
Journal: Nature
Title: Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing.
Volume: 480
Issue: 7376
Pages: 264-7
Publication
First Author: Qiao D
Year: 2002
Journal: Oncogene
Title: Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas.
Volume: 21
Issue: 25
Pages: 3988-99
GXD Expression      
Probe: MGI:3614463
Assay Type: RT-PCR
Annotation Date: 2006-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616218
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3614463
Assay Type: RT-PCR
Annotation Date: 2006-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616218
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3701286
Assay Type: RT-PCR
Annotation Date: 2007-03-28
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3701326
Age: postnatal
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3701286
Assay Type: RT-PCR
Annotation Date: 2007-03-28
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3701326
Age: postnatal
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3701286
Assay Type: RT-PCR
Annotation Date: 2007-03-28
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3701326
Age: postnatal
Specimen Label: -/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5507817
Assay Type: Northern blot
Annotation Date: 2013-09-23
Strength: Absent
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5507821
Age: postnatal adult
Image: 3
Specimen Label: Ovary
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5507817
Assay Type: Northern blot
Annotation Date: 2013-09-23
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5507821
Age: postnatal adult
Image: 3
Specimen Label: Testis
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5507817
Assay Type: Northern blot
Annotation Date: 2013-09-23
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5507821
Age: postnatal adult
Image: 3
Specimen Label: Lung
Specimen Num: 4
GXD Expression      
Probe: MGI:5507817
Assay Type: Northern blot
Annotation Date: 2013-09-23
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5507821
Age: postnatal adult
Image: 3
Specimen Label: Thymus
Specimen Num: 5
GXD Expression      
Probe: MGI:5507817
Assay Type: Northern blot
Annotation Date: 2013-09-23
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5507821
Age: postnatal adult
Image: 3
Specimen Label: Spleen
Specimen Num: 6
GXD Expression    
Probe: MGI:5507817
Assay Type: Northern blot
Annotation Date: 2013-09-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5507821
Age: postnatal adult
Image: 3
Specimen Label: Liver
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:5507817
Assay Type: Northern blot
Annotation Date: 2013-09-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5507821
Age: postnatal adult
Image: 3
Specimen Label: Kidney
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:5507817
Assay Type: Northern blot
Annotation Date: 2013-09-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5507821
Age: postnatal adult
Image: 3
Specimen Label: Heart
Detected: false
Specimen Num: 9
GXD Expression    
Probe: MGI:5507817
Assay Type: Northern blot
Annotation Date: 2013-09-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5507821
Age: postnatal adult
Image: 3
Specimen Label: Brain
Detected: false
Specimen Num: 10
GXD Expression    
Probe: MGI:5507817
Assay Type: Northern blot
Annotation Date: 2013-09-23
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5507823
Age: postnatal adult
Image: 4
Specimen Label: C57BL/6
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5507817
Assay Type: Northern blot
Annotation Date: 2013-09-23
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5507823
Age: postnatal adult
Image: 4
Specimen Label: W/W
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5507976
Age: postnatal adult
Image: 4
Specimen Label: C57BL/6
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5507976
Age: postnatal adult
Image: 4
Specimen Label: W/W
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Male
Emaps: EMAPS:1797220
Stage: TS20
Assay Id: MGI:5507985
Age: embryonic day 12.5
Image: 5
Specimen Label: E12.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Male
Emaps: EMAPS:1797221
Stage: TS21
Assay Id: MGI:5507985
Age: embryonic day 13.5
Image: 5
Specimen Label: E13.5
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Male
Emaps: EMAPS:1797222
Stage: TS22
Assay Id: MGI:5507985
Age: embryonic day 14.5
Image: 5
Specimen Label: E14.5
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Male
Emaps: EMAPS:1797223
Stage: TS23
Assay Id: MGI:5507985
Age: embryonic day 15.5
Image: 5
Specimen Label: E15.5
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:5507985
Age: embryonic day 16.5
Image: 5
Specimen Label: E16.5
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Male
Emaps: EMAPS:1797226
Stage: TS26
Assay Id: MGI:5507985
Age: embryonic day 18.5
Image: 5
Specimen Label: E18.5
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Male
Emaps: EMAPS:1797227
Stage: TS27
Assay Id: MGI:5507985
Age: postnatal newborn
Image: 5
Specimen Label: New Born
Detected: false
Specimen Num: 7
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5507985
Age: postnatal week 1
Image: 5
Specimen Label: 1W
Detected: false
Specimen Num: 8
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5507985
Age: postnatal week 2
Image: 5
Specimen Label: 2W
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5507985
Age: postnatal week 3
Image: 5
Specimen Label: 3W
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5507985
Age: postnatal adult
Image: 5
Specimen Label: Adult
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Female
Emaps: EMAPS:1796220
Stage: TS20
Assay Id: MGI:5507988
Age: embryonic day 12.5
Image: 5
Specimen Label: E12.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Female
Emaps: EMAPS:1796221
Stage: TS21
Assay Id: MGI:5507988
Age: embryonic day 13.5
Image: 5
Specimen Label: E13.5
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Female
Emaps: EMAPS:1796222
Stage: TS22
Assay Id: MGI:5507988
Age: embryonic day 14.5
Image: 5
Specimen Label: E14.5
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5507988
Age: embryonic day 15.5
Image: 5
Specimen Label: E15.5
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Female
Emaps: EMAPS:1796224
Stage: TS24
Assay Id: MGI:5507988
Age: embryonic day 16.5
Image: 5
Specimen Label: E16.5
Detected: false
Specimen Num: 5
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Female
Emaps: EMAPS:1796226
Stage: TS26
Assay Id: MGI:5507988
Age: embryonic day 18.5
Image: 5
Specimen Label: E18.5
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:5507887
Assay Type: RT-PCR
Annotation Date: 2013-09-24
Strength: Absent
Sex: Female
Emaps: EMAPS:1796227
Stage: TS27
Assay Id: MGI:5507988
Age: postnatal newborn
Image: 5
Specimen Label: New Born
Detected: false
Specimen Num: 7