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Search results 1 to 100 out of 141 for Pkd2l1

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Hits by Strain

Type Details Score
Gene
Type: gene
Organism: human
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Gene
Type: gene
Organism: frog, western clawed
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Gene
Type: gene
Organism: rat
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Gene
Type: gene
Organism: dog, domestic
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Gene
Type: gene
Organism: chimpanzee
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Gene
Type: gene
Organism: cattle
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Gene
Type: gene
Organism: chicken
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Gene
Type: gene
Organism: zebrafish
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Gene
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression    
Probe: MGI:4423148
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1755023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4827228
Age: embryonic day 14.5
Specimen Label: Table S5 - Pkd2l1
Detected: true
Specimen Num: 1
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GXD Expression    
Probe: MGI:4423148
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4827228
Age: embryonic day 14.5
Specimen Label: Table S5 - Pkd2l1
Detected: true
Specimen Num: 1
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Publication
First Author: Murakami M
Year: 2022
Journal: PLoS One
Title: Enhanced ?-adrenergic response in mice with dominant-negative expression of the PKD2L1 channel.
Volume: 17
Issue: 1
Pages: e0261668
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Publication
First Author: Lu Z
Year: 2018
Journal: Cell Rep
Title: Deficiency of PKD2L1 (TRPP3) Exacerbates Pathological Cardiac Hypertrophy by Augmenting NCX1-Mediated Mitochondrial Calcium Overload.
Volume: 24
Issue: 6
Pages: 1639-1652
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Publication
First Author: Ishimaru Y
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Transient receptor potential family members PKD1L3 and PKD2L1 form a candidate sour taste receptor.
Volume: 103
Issue: 33
Pages: 12569-74
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Publication
First Author: Fujimoto C
Year: 2011
Journal: Biochem Biophys Res Commun
Title: The single pore residue Asp523 in PKD2L1 determines Ca2+ permeation of the PKD1L3/PKD2L1 complex.
Volume: 404
Issue: 4
Pages: 946-51
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Publication
First Author: Ishimaru Y
Year: 2010
Journal: FASEB J
Title: Interaction between PKD1L3 and PKD2L1 through their transmembrane domains is required for localization of PKD2L1 at taste pores in taste cells of circumvallate and foliate papillae.
Volume: 24
Issue: 10
Pages: 4058-67
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Publication
First Author: Molland KL
Year: 2010
Journal: Biochem J
Title: Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2.
Volume: 429
Issue: 1
Pages: 171-83
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Publication
First Author: Shimizu T
Year: 2017
Journal: FEBS Open Bio
Title: The asparagine 533 residue in the outer pore loop region of the mouse PKD2L1 channel is essential for its voltage-dependent inactivation.
Volume: 7
Issue: 9
Pages: 1392-1401
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Publication
First Author: Su Q
Year: 2018
Journal: Nat Commun
Title: Cryo-EM structure of the polycystic kidney disease-like channel PKD2L1.
Volume: 9
Issue: 1
Pages: 1192
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Publication
First Author: Vien TN
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Primary cilia TRP channel regulates hippocampal excitability.
Volume: 120
Issue: 22
Pages: e2219686120
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Publication
First Author: Jur?i? N
Year: 2021
Journal: Eur J Neurosci
Title: Evidence for PKD2L1-positive neurons distant from the central canal in the ventromedial spinal cord and medulla of the adult mouse.
Volume: 54
Issue: 3
Pages: 4781-4803
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Publication  
First Author: Orts-Del'Immagine A
Year: 2016
Journal: Neuropharmacology
Title: A single polycystic kidney disease 2-like 1 channel opening acts as a spike generator in cerebrospinal fluid-contacting neurons of adult mouse brainstem.
Volume: 101
Pages: 549-65
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Publication
First Author: Vandenbeuch A
Year: 2020
Journal: Chem Senses
Title: Optogenetic Activation of Type III Taste Cells Modulates Taste Responses.
Volume: 45
Issue: 7
Pages: 533-539
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Publication
First Author: Ishii S
Year: 2012
Journal: FEBS J
Title: The response of PKD1L3/PKD2L1 to acid stimuli is inhibited by capsaicin and its pungent analogs.
Volume: 279
Issue: 10
Pages: 1857-70
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Publication
First Author: Shimizu T
Year: 2023
Journal: Sci Rep
Title: Polycystic kidney disease 2-like 1 channel contributes to the bitter aftertaste perception of quinine.
Volume: 13
Issue: 1
Pages: 4271
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Publication
First Author: Huang AL
Year: 2006
Journal: Nature
Title: The cells and logic for mammalian sour taste detection.
Volume: 442
Issue: 7105
Pages: 934-8
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Publication
First Author: Orts-Del'immagine A
Year: 2012
Journal: J Physiol
Title: Properties of subependymal cerebrospinal fluid contacting neurones in the dorsal vagal complex of the mouse brainstem.
Volume: 590
Issue: 16
Pages: 3719-41
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Publication
First Author: DeCaen PG
Year: 2013
Journal: Nature
Title: Direct recording and molecular identification of the calcium channel of primary cilia.
Volume: 504
Issue: 7479
Pages: 315-8
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Publication
First Author: Crozat E
Year: 2025
Journal: Commun Biol
Title: Cerebrospinal fluid-contacting neurons are sensory neurons with uniform morphological and region-specific electrophysiological properties in the mouse spinal cord.
Volume: 8
Issue: 1
Pages: 1233
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Publication
First Author: Murakami M
Year: 2005
Journal: J Biol Chem
Title: Genomic organization and functional analysis of murine PKD2L1.
Volume: 280
Issue: 7
Pages: 5626-35
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Publication
First Author: Chang RB
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: A proton current drives action potentials in genetically identified sour taste cells.
Volume: 107
Issue: 51
Pages: 22320-5
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Publication
First Author: Su Q
Year: 2021
Journal: Nat Commun
Title: Structural basis for Ca(2+) activation of the heteromeric PKD1L3/PKD2L1 channel.
Volume: 12
Issue: 1
Pages: 4871
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Publication
First Author: Wilson CE
Year: 2017
Journal: Chem Senses
Title: Type III Cells in Anterior Taste Fields Are More Immunohistochemically Diverse Than Those of Posterior Taste Fields in Mice.
Volume: 42
Issue: 9
Pages: 759-767
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Publication
First Author: Kawaguchi H
Year: 2010
Journal: J Biol Chem
Title: Activation of polycystic kidney disease-2-like 1 (PKD2L1)-PKD1L3 complex by acid in mouse taste cells.
Volume: 285
Issue: 23
Pages: 17277-81
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Publication
First Author: Horio N
Year: 2011
Journal: PLoS One
Title: Sour taste responses in mice lacking PKD channels.
Volume: 6
Issue: 5
Pages: e20007
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Publication
First Author: LopezJimenez ND
Year: 2006
Journal: J Neurochem
Title: Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.
Volume: 98
Issue: 1
Pages: 68-77
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Publication
First Author: Petracca YL
Year: 2016
Journal: Development
Title: The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cord.
Volume: 143
Issue: 5
Pages: 880-91
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
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Publication
First Author: Nomura H
Year: 1998
Journal: J Biol Chem
Title: Identification of PKDL, a novel polycystic kidney disease 2-like gene whose murine homologue is deleted in mice with kidney and retinal defects.
Volume: 273
Issue: 40
Pages: 25967-73
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Publication  
First Author: Leblond L
Year: 2025
Journal: Front Neuroanat
Title: Spinal cord morphology and PKD2L1(+) cells distribution: effects of age, sex, and spinal segment in mice.
Volume: 19
Pages: 1652848
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Publication  
First Author: Wilson CE
Year: 2019
Journal: eNeuro
Title: Physiological and Behavioral Responses to Optogenetic Stimulation of PKD2L1(+) Type III Taste Cells.
Volume: 6
Issue: 2
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Publication  
First Author: Kaplan JP
Year: 2025
Journal: J Neurosci
Title: Epitope Tagging with Genome Editing in Mice Reveals That the Proton Channel OTOP1 Is Apically Localized and Not Restricted to Type III "Sour" Taste Receptor Cells.
Volume: 45
Issue: 6
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GXD Expression      
Probe: MGI:4822005
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759725
Stage: TS25
Assay Id: MGI:4822344
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 1
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GXD Expression      
Probe: MGI:4822005
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Stage: TS26
Assay Id: MGI:4822344
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 2
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GXD Expression      
Probe: MGI:4822005
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4822344
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 3
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GXD Expression      
Probe: MGI:4822005
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4822344
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 4
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GXD Expression      
Probe: MGI:4822005
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4822344
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 5
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GXD Expression      
Probe: MGI:4822005
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4822344
Age: postnatal day 6
Specimen Label: P6
Detected: true
Specimen Num: 6
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GXD Expression      
Probe: MGI:4822005
Assay Type: RT-PCR
Annotation Date: 2010-09-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4822344
Age: postnatal day 8
Specimen Label: P8
Detected: true
Specimen Num: 7
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GXD Expression    
Probe: MGI:6690892
Assay Type: RT-PCR
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3743728
Stage: TS28
Assay Id: MGI:6693314
Age: postnatal adult
Image: 4
Specimen Label: Trkb W/W
Detected: true
Specimen Num: 1
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GXD Expression    
Probe: MGI:6690892
Assay Type: RT-PCR
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3743728
Stage: TS28
Assay Id: MGI:6693314
Age: postnatal adult
Image: 4
Specimen Label: Trkb P/P
Detected: true
Specimen Num: 2
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GXD Expression    
Probe: MGI:6690892
Assay Type: RT-PCR
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3743728
Stage: TS28
Assay Id: MGI:6693323
Age: postnatal adult
Image: 4
Specimen Label: Trkb +/+
Detected: true
Specimen Num: 1
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GXD Expression    
Probe: MGI:6690892
Assay Type: RT-PCR
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3743728
Stage: TS28
Assay Id: MGI:6693323
Age: postnatal adult
Image: 4
Specimen Label: Trkb S/S
Detected: true
Specimen Num: 2
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GXD Expression      
Probe: MGI:5766196
Assay Type: RNA in situ
Annotation Date: 2016-05-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1788128
Stage: TS28
Assay Id: MGI:5766203
Age: postnatal
Specimen Label: 6
Detected: false
Specimen Num: 1
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GXD Expression  
Probe: MGI:4423148
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1857623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827228
Age: embryonic day 14.5
Image: euxassay_008065_11
Specimen Label: euxassay_008065_11
Detected: true
Specimen Num: 2
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GXD Expression  
Probe: MGI:4423148
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1857623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827228
Age: embryonic day 14.5
Image: euxassay_008065_12
Specimen Label: euxassay_008065_12
Detected: true
Specimen Num: 3
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GXD Expression  
Probe: MGI:4423148
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1857623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827228
Age: embryonic day 14.5
Image: euxassay_008065_13
Specimen Label: euxassay_008065_13
Detected: true
Specimen Num: 4
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GXD Expression  
Probe: MGI:4423148
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1857623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827228
Age: embryonic day 14.5
Image: euxassay_008065_14
Specimen Label: euxassay_008065_14
Detected: true
Specimen Num: 5
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GXD Expression  
Probe: MGI:4423148
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1857623
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827228
Age: embryonic day 14.5
Image: euxassay_008065_15
Specimen Label: euxassay_008065_15
Detected: true
Specimen Num: 6
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GXD Expression  
Probe: MGI:5766196
Assay Type: RNA in situ
Annotation Date: 2016-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1827128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5766203
Age: postnatal
Note: Expression is in a subset of taste receptor cells.
Specimen Label: 6
Detected: true
Specimen Num: 1
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GXD Expression  
Probe: MGI:5766196
Assay Type: RNA in situ
Annotation Date: 2016-05-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1827128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5766203
Age: postnatal
Note: Expression is in a subset of taste receptor cells.
Specimen Label: 7
Detected: true
Specimen Num: 2
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Publication
First Author: Chandrashekar J
Year: 2009
Journal: Science
Title: The taste of carbonation.
Volume: 326
Issue: 5951
Pages: 443-5
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Publication
First Author: Zocchi D
Year: 2017
Journal: Nat Neurosci
Title: The cellular mechanism for water detection in the mammalian taste system.
Volume: 20
Issue: 7
Pages: 927-933
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Publication
First Author: Li Q
Year: 2003
Journal: Biochemistry
Title: Troponin I binds polycystin-L and inhibits its calcium-induced channel activation.
Volume: 42
Issue: 24
Pages: 7618-25
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Publication
First Author: Inada H
Year: 2008
Journal: EMBO Rep
Title: Off-response property of an acid-activated cation channel complex PKD1L3-PKD2L1.
Volume: 9
Issue: 7
Pages: 690-7
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Publication
First Author: Ishii S
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Acetic acid activates PKD1L3-PKD2L1 channel--a candidate sour taste receptor.
Volume: 385
Issue: 3
Pages: 346-50
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Publication  
First Author: Grosch M
Year: 2021
Journal: J Cell Sci
Title: A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.
Volume: 134
Issue: 16
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Publication
First Author: Gerstmann K
Year: 2022
Journal: Curr Biol
Title: The role of intraspinal sensory neurons in the control of quadrupedal locomotion.
Volume: 32
Issue: 11
Pages: 2442-2453.e4
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Publication  
First Author: Riondel P
Year: 2024
Journal: J Neurosci
Title: Evidence for Two Subpopulations of Cerebrospinal Fluid-Contacting Neurons with Opposite GABAergic Signaling in Adult Mouse Spinal Cord.
Volume: 44
Issue: 22
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Publication
First Author: Orts-Del'Immagine A
Year: 2014
Journal: PLoS One
Title: Morphology, distribution and phenotype of polycystin kidney disease 2-like 1-positive cerebrospinal fluid contacting neurons in the brainstem of adult mice.
Volume: 9
Issue: 2
Pages: e87748
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Publication    
First Author: Nakamura Y
Year: 2023
Journal: Elife
Title: Cerebrospinal fluid-contacting neuron tracing reveals structural and functional connectivity for locomotion in the mouse spinal cord.
Volume: 12
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Publication
First Author: Yao G
Year: 2016
Journal: Hum Mol Genet
Title: Disruption of polycystin-L causes hippocampal and thalamocortical hyperexcitability.
Volume: 25
Issue: 3
Pages: 448-58
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Publication
First Author: Kaja S
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Polycystin-2 expression and function in adult mouse lacrimal acinar cells.
Volume: 52
Issue: 8
Pages: 5605-11
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Publication
First Author: Toscano E
Year: 2025
Journal: Curr Biol
Title: A spinal circuit for skilled locomotion.
Volume: 35
Issue: 20
Pages: 5048-5059.e5
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Publication
First Author: Wu X
Year: 2016
Journal: PLoS One
Title: Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.
Volume: 11
Issue: 5
Pages: e0155577
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Publication
First Author: Ye W
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction.
Volume: 113
Issue: 2
Pages: E229-38
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Publication
First Author: Delling M
Year: 2013
Journal: Nature
Title: Primary cilia are specialized calcium signalling organelles.
Volume: 504
Issue: 7479
Pages: 311-4
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Publication  
First Author: Koudelka J
Year: 2014
Journal: Neural Dev
Title: Genetic dissection of TrkB activated signalling pathways required for specific aspects of the taste system.
Volume: 9
Pages: 21
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Publication
First Author: Di Bella DJ
Year: 2019
Journal: Cell Rep
Title: Ascl1 Balances Neuronal versus Ependymal Fate in the Spinal Cord Central Canal.
Volume: 28
Issue: 9
Pages: 2264-2274.e3
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Publication    
First Author: Fan D
Year: 2019
Journal: Elife
Title: Taste bud formation depends on taste nerves.
Volume: 8
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Publication
First Author: Frederico B
Year: 2022
Journal: Dev Cell
Title: DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential.
Volume: 57
Issue: 16
Pages: 1957-1975.e9
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