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Search results 1 to 100 out of 488 for Pkm

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: de Luis O
Year: 1998
Journal: Biochim Biophys Acta
Title: Gene expression of mouse M1 and M2 pyruvate kinase isoenzymes correlates with differential poly[A] tract extension of their mRNAs during the development of spermatogenesis.
Volume: 1396
Issue: 3
Pages: 294-305
Publication
First Author: Izumi S
Year: 1995
Journal: Biochim Biophys Acta
Title: Molecular cloning of the complementary DNA for the mouse pyruvate kinase M-2 gene whose expression is dependent upon cell differentiation.
Volume: 1267
Issue: 2-3
Pages: 135-8
Publication
First Author: Lee J
Year: 2008
Journal: Int J Biochem Cell Biol
Title: Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription.
Volume: 40
Issue: 5
Pages: 1043-54
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Publication
First Author: Simsek D
Year: 2017
Journal: Cell
Title: The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity.
Volume: 169
Issue: 6
Pages: 1051-1065.e18
Publication
First Author: Deng W
Year: 2018
Journal: Cell Rep
Title: The Circadian Clock Controls Immune Checkpoint Pathway in Sepsis.
Volume: 24
Issue: 2
Pages: 366-378
Publication
First Author: Tech K
Year: 2017
Journal: Cancer Res
Title: Pyruvate Kinase Inhibits Proliferation during Postnatal Cerebellar Neurogenesis and Suppresses Medulloblastoma Formation.
Volume: 77
Issue: 12
Pages: 3217-3230
Publication
First Author: Morita M
Year: 2018
Journal: Cancer Cell
Title: PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.
Volume: 33
Issue: 3
Pages: 355-367.e7
Publication
First Author: Gao Z
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Reexpression of pyruvate kinase M2 in type 1 myofibers correlates with altered glucose metabolism in myotonic dystrophy.
Volume: 110
Issue: 33
Pages: 13570-5
Publication  
First Author: Lin JC
Year: 2016
Journal: Sci Rep
Title: RBM4a-regulated splicing cascade modulates the differentiation and metabolic activities of brown adipocytes.
Volume: 6
Pages: 20665
Publication  
First Author: Su CH
Year: 2017
Journal: Mol Cell Biol
Title: RBM4 Regulates Neuronal Differentiation of Mesenchymal Stem Cells by Modulating Alternative Splicing of Pyruvate Kinase M.
Volume: 37
Issue: 3
Publication
First Author: Dayton TL
Year: 2016
Journal: Genes Dev
Title: Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma.
Volume: 30
Issue: 9
Pages: 1020-33
Publication
First Author: Ni L
Year: 2022
Journal: J Am Heart Assoc
Title: Pyruvate Kinase M2 Protects Heart from Pressure Overload-Induced Heart Failure by Phosphorylating RAC1.
Volume: 11
Issue: 11
Pages: e024854
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Publication
First Author: Sun X
Year: 2019
Journal: Mucosal Immunol
Title: Intestinal epithelial PKM2 serves as a safeguard against experimental colitis via activating β-catenin signaling.
Volume: 12
Issue: 6
Pages: 1280-1290
Publication
First Author: Xia Y
Year: 2022
Journal: Cancer Res
Title: PKM2 Is Essential for Bladder Cancer Growth and Maintenance.
Volume: 82
Issue: 4
Pages: 571-585
Publication
First Author: Nayak MK
Year: 2021
Journal: Blood
Title: The metabolic enzyme pyruvate kinase M2 regulates platelet function and arterial thrombosis.
Volume: 137
Issue: 12
Pages: 1658-1668
Publication
First Author: Manuel AM
Year: 2021
Journal: Am J Respir Cell Mol Biol
Title: Dysregulation of Pyruvate Kinase M2 Promotes Inflammation in a Mouse Model of Obese Allergic Asthma.
Volume: 64
Issue: 6
Pages: 709-721
Publication
First Author: Wubben TJ
Year: 2017
Journal: Sci Rep
Title: Photoreceptor metabolic reprogramming provides survival advantage in acute stress while causing chronic degeneration.
Volume: 7
Issue: 1
Pages: 17863
Publication
First Author: Stone OA
Year: 2018
Journal: Nat Commun
Title: Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells.
Volume: 9
Issue: 1
Pages: 4077
Publication
First Author: Ye Y
Year: 2021
Journal: FASEB J
Title: Pyruvate kinase M2 mediates fibroblast proliferation to promote tubular epithelial cell survival in acute kidney injury.
Volume: 35
Issue: 7
Pages: e21706
Publication
First Author: McKnight SL
Year: 2014
Journal: Mol Cell
Title: Please keep me 2uned to PKM2.
Volume: 53
Issue: 5
Pages: 683-4
Publication
First Author: Jain M
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: Smooth Muscle Cell-Specific PKM2 (Pyruvate Kinase Muscle 2) Promotes Smooth Muscle Cell Phenotypic Switching and Neointimal Hyperplasia.
Volume: 41
Issue: 5
Pages: 1724-1737
Publication
First Author: Kim B
Year: 2018
Journal: J Clin Invest
Title: Endothelial pyruvate kinase M2 maintains vascular integrity.
Volume: 128
Issue: 10
Pages: 4543-4556
Publication
First Author: Rajala A
Year: 2018
Journal: Cell Death Dis
Title: Pyruvate kinase M2 isoform deletion in cone photoreceptors results in age-related cone degeneration.
Volume: 9
Issue: 7
Pages: 737
Publication
First Author: Li Q
Year: 2021
Journal: Circulation
Title: PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart.
Volume: 144
Issue: 9
Pages: 712-727
Publication
First Author: Palsson-McDermott EM
Year: 2015
Journal: Cell Metab
Title: Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages.
Volume: 21
Issue: 1
Pages: 65-80
Publication  
First Author: Nash HR
Year: 1978
Journal: Mouse News Lett
Title: Strain distribution pattern of Pk-2, now Pk-3
Volume: 59
Pages: 31
Publication
First Author: Wu X
Year: 2008
Journal: FEBS Lett
Title: Isoform-specific interaction of pyruvate kinase with hepatitis C virus NS5B.
Volume: 582
Issue: 15
Pages: 2155-60
Publication
First Author: Zafar S
Year: 2014
Journal: Mol Neurobiol
Title: Anchorless 23-230 PrPC interactomics for elucidation of PrPC protective role.
Volume: 49
Issue: 3
Pages: 1385-99
Publication
First Author: Casson RJ
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: M-Type Pyruvate Kinase Isoforms and Lactate Dehydrogenase A in the Mammalian Retina: Metabolic Implications.
Volume: 57
Issue: 1
Pages: 66-80
Publication
First Author: Méndez-Lucas A
Year: 2017
Journal: Cancer Res
Title: Glucose Catabolism in Liver Tumors Induced by c-MYC Can Be Sustained by Various PKM1/PKM2 Ratios and Pyruvate Kinase Activities.
Volume: 77
Issue: 16
Pages: 4355-4364
Publication
First Author: Christofk HR
Year: 2008
Journal: Nature
Title: Pyruvate kinase M2 is a phosphotyrosine-binding protein.
Volume: 452
Issue: 7184
Pages: 181-6
Publication
First Author: Hamabe A
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition.
Volume: 111
Issue: 43
Pages: 15526-31
Publication
First Author: Lunt SY
Year: 2015
Journal: Mol Cell
Title: Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation.
Volume: 57
Issue: 1
Pages: 95-107
Publication
First Author: Hosios AM
Year: 2015
Journal: Mol Cell
Title: Lack of Evidence for PKM2 Protein Kinase Activity.
Volume: 59
Issue: 5
Pages: 850-7
Publication
First Author: Bravo-Adame ME
Year: 2017
Journal: Immunology
Title: An alternative mode of CD43 signal transduction activates pro-survival pathways of T lymphocytes.
Volume: 150
Issue: 1
Pages: 87-99
Publication  
First Author: Cai SZ
Year: 2019
Journal: Biosci Rep
Title: Allicin alleviates lead-induced hematopoietic stem cell aging by up-regulating PKM2.
Volume: 39
Issue: 7
Publication
First Author: Kodani A
Year: 2019
Journal: J Neurotrauma
Title: Acteoside Improves Muscle Atrophy and Motor Function by Inducing New Myokine Secretion in Chronic Spinal Cord Injury.
Volume: 36
Issue: 12
Pages: 1935-1948
Publication
First Author: Gómez-Escudero J
Year: 2019
Journal: Sci Rep
Title: PKM2 regulates endothelial cell junction dynamics and angiogenesis via ATP production.
Volume: 9
Issue: 1
Pages: 15022
Publication
First Author: Zheng D
Year: 2020
Journal: Am J Pathol
Title: Pyruvate Kinase M2 Tetramerization Protects against Hepatic Stellate Cell Activation and Liver Fibrosis.
Volume: 190
Issue: 11
Pages: 2267-2281
Publication
First Author: Yuan Q
Year: 2020
Journal: Cell Death Dis
Title: Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiation.
Volume: 11
Issue: 5
Pages: 355
Publication  
First Author: Dang G
Year: 2022
Journal: Redox Biol
Title: T lymphocyte-derived extracellular vesicles aggravate abdominal aortic aneurysm by promoting macrophage lipid peroxidation and migration via pyruvate kinase muscle isozyme 2.
Volume: 50
Pages: 102257
Publication  
First Author: Fu J
Year: 2022
Journal: JCI Insight
Title: Regeneration of glomerular metabolism and function by podocyte pyruvate kinase M2 in diabetic nephropathy.
Volume: 7
Issue: 5
GXD Expression      
Probe: MGI:1261515
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804541
Age: postnatal day 6
Specimen Label: Testis 6
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1261515
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804541
Age: postnatal day 10
Specimen Label: Testis 10
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1261515
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804541
Age: postnatal day 14
Specimen Label: Testis 14
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1261515
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804541
Age: postnatal day 22
Specimen Label: Testis 22
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1261515
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804541
Age: postnatal adult
Specimen Label: Testis A
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1261515
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737327
Stage: TS27
Assay Id: MGI:3804541
Age: postnatal newborn
Specimen Label: Kidn. Nb
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1261515
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3804541
Age: postnatal adult
Specimen Label: Kidn. Ad
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:1261515
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598827
Stage: TS27
Assay Id: MGI:3804541
Age: postnatal newborn
Specimen Label: Musc. Nb
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:1261515
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3804541
Age: postnatal adult
Specimen Label: Musc. Ad
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:1261515
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3804541
Age: postnatal newborn
Specimen Label: Brain Nb
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:1261515
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3804541
Age: postnatal adult
Specimen Label: Brain Ad
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:1261516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804546
Age: postnatal day 6
Specimen Label: Testis 6
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1261516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804546
Age: postnatal day 10
Specimen Label: Testis 10
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1261516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804546
Age: postnatal day 14
Specimen Label: Testis 14
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1261516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804546
Age: postnatal day 22
Specimen Label: Testis 22
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:1261516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804546
Age: postnatal adult
Specimen Label: Testis A
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1261516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737327
Stage: TS27
Assay Id: MGI:3804546
Age: postnatal newborn
Specimen Label: Kidn. Nb
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1261516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3804546
Age: postnatal adult
Specimen Label: Kidn. Ad
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:1261516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598827
Stage: TS27
Assay Id: MGI:3804546
Age: postnatal newborn
Specimen Label: Musc. Nb
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:1261516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3804546
Age: postnatal adult
Specimen Label: Musc. Ad
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:1261516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3804546
Age: postnatal newborn
Specimen Label: Brain Nb
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:1261516
Assay Type: Northern blot
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3804546
Age: postnatal adult
Specimen Label: Brain Ad
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:3804538
Assay Type: RT-PCR
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804547
Age: postnatal day 6
Specimen Label: T 6
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3804538
Assay Type: RT-PCR
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804547
Age: postnatal day 10
Specimen Label: T 10
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3804538
Assay Type: RT-PCR
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804547
Age: postnatal day 25
Specimen Label: T 25
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3804538
Assay Type: RT-PCR
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804547
Age: postnatal adult
Specimen Label: T AD
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3804538
Assay Type: RT-PCR
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3804547
Age: postnatal adult
Specimen Label: M AD
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3804538
Assay Type: RT-PCR
Annotation Date: 2008-09-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3804547
Age: postnatal adult
Specimen Label: Br AD
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3804539
Assay Type: RT-PCR
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804548
Age: postnatal day 6
Specimen Label: T 6
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3804539
Assay Type: RT-PCR
Annotation Date: 2008-09-05
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3804548
Age: postnatal day 10
Specimen Label: T 10
Detected: true
Specimen Num: 3