Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
PLAG1, PLAGL1 and PLAGL2 constitute a family of zinc finger proteins that recognise DNA and/or RNA. This entry represents PLAGL1 (pleiomorphic adenoma-like protein 1), also known as ZAC, which shows weak transcriptional activatory activity []. PLAGL1 is a transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide []. It has antiproliferative properties [, ]. |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Spengler D |
Year: |
1997 |
Journal: |
EMBO J |
Title: |
Regulation of apoptosis and cell cycle arrest by Zac1, a novel zinc finger protein expressed in the pituitary gland and the brain. |
Volume: |
16 |
Issue: |
10 |
Pages: |
2814-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chou WY |
Year: |
2008 |
Journal: |
Int J Biochem Cell Biol |
Title: |
Human Spot 14 protein is a p53-dependent transcriptional coactivator via the recruitment of thyroid receptor and Zac1. |
Volume: |
40 |
Issue: |
9 |
Pages: |
1826-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kas K |
Year: |
1998 |
Journal: |
J Biol Chem |
Title: |
Transcriptional activation capacity of the novel PLAG family of zinc finger proteins. |
Volume: |
273 |
Issue: |
36 |
Pages: |
23026-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Varrault A |
Year: |
1998 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer. |
Volume: |
95 |
Issue: |
15 |
Pages: |
8835-40 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 14.5 |
Image: |
Plagl1 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Plagl1 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271222 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 14.5 |
Image: |
Plagl1 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Plagl1 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754322 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 14.5 |
Image: |
Plagl1 - E14.5 |
Note: |
There is strong staining in the ventricular zone of the prethalamus and weak staining in the dorsal thalamus. |
Specimen Label: |
Plagl1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 14.5 |
Image: |
Plagl1 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
Specimen Label: |
Plagl1 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271820 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 12.5 |
Image: |
Plagl1 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT. |
Specimen Label: |
Plagl1 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1690819 |
Pattern: |
Non-Uniform |
Stage: |
TS19 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 11.5 |
Image: |
Plagl1 - E11.5 |
Note: |
Staining is strong in the VZ of the dorsal thalamus, prethalamus, ventral POA, the AVH, the VMH & ARH nuclei & premam zone, weak in anterior & posterior IDs, the TT & the mam & supramam zones & either absent or ubiquitous in the dorsal POA & PVH nucleus. |
Specimen Label: |
Plagl1 - E11.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Very strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753922 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 14.5 |
Image: |
Plagl1 - E14.5 |
Note: |
There is very strong staining in the VZ of the ARH nucleus, strong staining in the VMH nucleus & moderate staining in the ventral POA & the AVH. Staining is either absent or ubiquitous in the VZ of the dorsal POA, PVH nucleus & anterior & posterior IDs. |
Specimen Label: |
Plagl1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Very strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753924 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 16.5 |
Image: |
Plagl1 - E16.5 |
Note: |
There is very strong staining in the VZ of the PH, strong staining in the AVH and ARH nucleus and moderate staining in the dorsal and ventral POAs. Staining is either absent or ubiquitous in the VZ of the PVH, SCH, DMH and VMH nuclei and the DAH. |
Specimen Label: |
Plagl1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754720 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 12.5 |
Image: |
Plagl1 - E12.5 |
Note: |
There is moderate staining in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Plagl1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271020 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 12.5 |
Image: |
Plagl1 - E12.5 |
Note: |
There is strong staining in the ventricular zone of the premam and mam zones and the TT. Staining is either absent or ubiquitous in the ventricular zone of the supramam zone. |
Specimen Label: |
Plagl1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Very strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271024 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 16.5 |
Image: |
Plagl1 - E16.5 |
Note: |
There is very strong staining in the ventricular zone of the premam and mam zones. Staining is either absent or ubiquitous in the ventricular zone of the supramam zone. |
Specimen Label: |
Plagl1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266520 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 12.5 |
Image: |
Plagl1 - E12.5 |
Note: |
There is weak staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences. |
Specimen Label: |
Plagl1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266524 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 16.5 |
Image: |
Plagl1 - E16.5 |
Note: |
There is weak staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences. |
Specimen Label: |
Plagl1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1690619 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 11.5 |
Image: |
Plagl1 - E11.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus, prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT. |
Specimen Label: |
Plagl1 - E11.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754124 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 16.5 |
Image: |
Plagl1 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Plagl1 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 12.5 |
Image: |
Plagl1 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Plagl1 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271124 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 16.5 |
Image: |
Plagl1 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Plagl1 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271220 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 12.5 |
Image: |
Plagl1 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Plagl1 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271224 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 16.5 |
Image: |
Plagl1 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Plagl1 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754320 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 12.5 |
Image: |
Plagl1 - E12.5 |
Note: |
There is strong staining in the ventricular zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Plagl1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754324 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 16.5 |
Image: |
Plagl1 - E16.5 |
Note: |
There is strong staining in the ventricular zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Plagl1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753720 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 12.5 |
Image: |
Plagl1 - E12.5 |
Note: |
There is strong staining in the mantle zone of the AVH. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei and anterior and posterior IDs. |
Specimen Label: |
Plagl1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753724 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 16.5 |
Image: |
Plagl1 - E16.5 |
Note: |
There is strong, scattered staining in the mantle zone of the PH. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH and the DAH. |
Specimen Label: |
Plagl1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691319 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 11.5 |
Image: |
Plagl1 - E11.5 |
Note: |
There is weak staining in the ventricular zone of the cerebral cortex and the ganglionic eminences. |
Specimen Label: |
Plagl1 - E11.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271822 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 14.5 |
Image: |
Plagl1 - E14.5 |
Note: |
There is moderate, scattered staining in the mantle zone of the premam zone and the TT. Staining is either absent or ubiquitous in the mantle zone of the mam and supramam zone. |
Specimen Label: |
Plagl1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271824 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 16.5 |
Image: |
Plagl1 - E16.5 |
Note: |
There is strong, scattered staining in the mantle zone of the premam zone. Staining is either absent or ubiquitous in the mantle zone of the mam and supramam zones. |
Specimen Label: |
Plagl1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753920 |
Pattern: |
Non-Uniform |
Stage: |
TS20 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 12.5 |
Image: |
Plagl1 - E12.5 |
Note: |
There is strong staining in the ventricular zone of the ventral POA and VMH and ARH nuclei. Staining is either absent or ubiquitous in the ventricular zone of the dorsal POA, the PVH nucleus, the AVH and anterior and posterior IDs. |
Specimen Label: |
Plagl1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691119 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 11.5 |
Image: |
Plagl1 - E11.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences. |
Specimen Label: |
Plagl1 - E11.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Very strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 14.5 |
Image: |
Plagl1 - E14.5 |
Note: |
There is very strong staining in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Plagl1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Very strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754724 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 16.5 |
Image: |
Plagl1 - E16.5 |
Note: |
There is very strong staining in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Plagl1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Very strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271022 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 14.5 |
Image: |
Plagl1 - E14.5 |
Note: |
There is very strong staining in the ventricular zone of the premam zone, strong staining in the mam zone and moderate staining in the TT. Staining is either absent or ubiquitous in the ventricular zone of the supramam zone. |
Specimen Label: |
Plagl1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266522 |
Pattern: |
Non-Uniform |
Stage: |
TS22 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 14.5 |
Image: |
Plagl1 - E14.5 |
Note: |
There is moderate staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences. |
Specimen Label: |
Plagl1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 12.5 |
Image: |
Plagl1 - E12.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Plagl1 - E12.5 |
|
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442778 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450754 |
Age: |
embryonic day 14.5 |
Image: |
Plagl1 - E14.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Plagl1 - E14.5 |
|
Specimen Num: |
3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iglesias-Platas I |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Characterization of novel paternal ncRNAs at the Plagl1 locus, including Hymai, predicted to interact with regulators of active chromatin. |
Volume: |
7 |
Issue: |
6 |
Pages: |
e38907 |
|
•
•
•
•
•
|
Publication |
First Author: |
Anderson AA |
Year: |
2009 |
Journal: |
Pathogenetics |
Title: |
Pancreatic islet expression profiling in diabetes-prone C57BLKS/J mice reveals transcriptional differences contributed by DBA loci, including Plagl1 and Nnt. |
Volume: |
2 |
Issue: |
1 |
Pages: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6180754 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6191089 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Plagl1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6180754 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6191089 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Plagl1 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6180754 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6191089 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Plagl1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6180754 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6191089 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Plagl1 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6180754 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191089 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Plagl1 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6180754 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191089 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Plagl1 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6180754 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191089 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Plagl1 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
678
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Varrault A |
Year: |
2017 |
Journal: |
Nucleic Acids Res |
Title: |
Identification of Plagl1/Zac1 binding sites and target genes establishes its role in the regulation of extracellular matrix genes and the imprinted gene network. |
Volume: |
45 |
Issue: |
18 |
Pages: |
10466-10480 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tanaka S |
Year: |
2019 |
Journal: |
Int J Mol Med |
Title: |
Involvement of PLAGL1/ZAC1 in hypocretin/orexin transcription. |
Volume: |
43 |
Issue: |
5 |
Pages: |
2164-2176 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma D |
Year: |
2004 |
Journal: |
J Clin Invest |
Title: |
Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM. |
Volume: |
114 |
Issue: |
3 |
Pages: |
339-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miró X |
Year: |
2009 |
Journal: |
Dis Model Mech |
Title: |
Haploinsufficiency of the murine polycomb gene Suz12 results in diverse malformations of the brain and neural tube. |
Volume: |
2 |
Issue: |
7-8 |
Pages: |
412-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lui JC |
Year: |
2008 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
An imprinted gene network that controls mammalian somatic growth is down-regulated during postnatal growth deceleration in multiple organs. |
Volume: |
295 |
Issue: |
1 |
Pages: |
R189-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Farhy C |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. |
Volume: |
8 |
Issue: |
9 |
Pages: |
e76489 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang SM |
Year: |
2000 |
Journal: |
Mol Cell Biol |
Title: |
Mouse Zac1, a transcriptional coactivator and repressor for nuclear receptors. |
Volume: |
20 |
Issue: |
5 |
Pages: |
1855-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Varrault A |
Year: |
2006 |
Journal: |
Dev Cell |
Title: |
Zac1 regulates an imprinted gene network critically involved in the control of embryonic growth. |
Volume: |
11 |
Issue: |
5 |
Pages: |
711-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vincent A |
Year: |
2012 |
Journal: |
Cardiovasc Res |
Title: |
Down-regulation of the transcription factor ZAC1 upon pre- and postconditioning protects against I/R injury in the mouse myocardium. |
Volume: |
94 |
Issue: |
2 |
Pages: |
351-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Valente T |
Year: |
2001 |
Journal: |
Mech Dev |
Title: |
Expression pattern of Zac1 mouse gene, a new zinc-finger protein that regulates apoptosis and cellular cycle arrest, in both adult brain and along development. |
Volume: |
108 |
Issue: |
1-2 |
Pages: |
207-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arima T |
Year: |
2000 |
Journal: |
Genomics |
Title: |
A novel imprinted gene, HYMAI, is located within an imprinted domain on human chromosome 6 containing ZAC. |
Volume: |
67 |
Issue: |
3 |
Pages: |
248-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pagotto U |
Year: |
1999 |
Journal: |
Endocrinology |
Title: |
Inhibition of Zac1, a new gene differentially expressed in the anterior pituitary, increases cell proliferation. |
Volume: |
140 |
Issue: |
2 |
Pages: |
987-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith RJ |
Year: |
2002 |
Journal: |
Gene |
Title: |
The mouse Zac1 locus: basis for imprinting and comparison with human ZAC. |
Volume: |
292 |
Issue: |
1-2 |
Pages: |
101-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma L |
Year: |
2007 |
Journal: |
Dev Dyn |
Title: |
Zac1 promotes a Müller glial cell fate and interferes with retinal ganglion cell differentiation in Xenopus retina. |
Volume: |
236 |
Issue: |
1 |
Pages: |
192-202 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hoffmann A |
Year: |
2008 |
Journal: |
Mol Cell Biol |
Title: |
A new coactivator function for Zac1's C2H2 zinc finger DNA-binding domain in selectively controlling PCAF activity. |
Volume: |
28 |
Issue: |
19 |
Pages: |
6078-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Theodoropoulou M |
Year: |
2010 |
Journal: |
Mol Cell Endocrinol |
Title: |
ZAC1 target genes and pituitary tumorigenesis. |
Volume: |
326 |
Issue: |
1-2 |
Pages: |
60-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang WM |
Year: |
2011 |
Journal: |
Biochim Biophys Acta |
Title: |
Zac1 functional interactions mediate AP-1 transcriptional activity. |
Volume: |
1813 |
Issue: |
12 |
Pages: |
2050-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Veselovska L |
Year: |
2015 |
Journal: |
Genome Biol |
Title: |
Deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the DNA methylation landscape. |
Volume: |
16 |
|
Pages: |
209 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2653853 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-04-08 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2576528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2653862 |
Age: |
postnatal adult |
|
|
Specimen Label: |
BL/6 (maternal) |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2653853 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-04-08 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:2576528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2653862 |
Age: |
postnatal adult |
|
|
Specimen Label: |
M. spretus (paternal) |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2653853 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610521 |
|
Stage: |
TS21 |
Assay Id: |
MGI:2653862 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Heart |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2653853 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1774321 |
|
Stage: |
TS21 |
Assay Id: |
MGI:2653862 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Skeletal muscle |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2653853 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
|
Stage: |
TS21 |
Assay Id: |
MGI:2653862 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Brain |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:2653853 |
Assay Type: |
RT-PCR |
Annotation Date: |
2003-04-08 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684621 |
|
Stage: |
TS21 |
Assay Id: |
MGI:2653862 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Liver |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|