|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 812 for Plat

<< First    < Previous  |  Next >    Last >>
0.082s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
5327 | PLAT
Type: gene
Organism: human
•
•
•
•
•
Gene
426791 | PLAT
Type: gene
Organism: chicken
•
•
•
•
•
Gene
100320028 | plat
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
704475 | PLAT
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
594962 | plat
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
281407 | PLAT
Type: gene
Organism: cattle
•
•
•
•
•
Gene
25692 | Plat
Type: gene
Organism: rat
•
•
•
•
•
Gene
482840 | PLAT
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
472748 | PLAT
Type: gene
Organism: chimpanzee
•
•
•
•
•
Protein Coding Gene
MGI:97610 | Plat
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
16957178 | J:117204
First Author: Plat J
Year: 2006
Journal: J Lipid Res
Title: Plant sterol or stanol esters retard lesion formation in LDL receptor-deficient mice independent of changes in serum plant sterols.
Volume: 47
Issue: 12
Pages: 2762-71
•
•
•
•
•
Gene
125336 | LOXHD1
Type: gene
Organism: human
•
•
•
•
•
Publication
30995314 | J:273649
First Author: Hu Y
Year: 2019
Journal: Invest Ophthalmol Vis Sci
Title: Investigations on the Role of the Fibrinolytic Pathway on Outflow Facility Regulation.
Volume: 60
Issue: 5
Pages: 1571-1580
•
•
•
•
•
Publication
27079292 | J:263529
First Author: Szabo R
Year: 2016
Journal: J Thromb Haemost
Title: Passenger mutations and aberrant gene expression in congenic tissue plasminogen activator-deficient mouse strains.
Volume: 14
Issue: 8
Pages: 1618-28
•
•
•
•
•
Publication
8088835 | J:18471
First Author: Lemaire L
Year: 1994
Journal: Genomics
Title: Chromosomal assignment of three novel mouse genes expressed in testicular cells.
Volume: 21
Issue: 2
Pages: 409-14
•
•
•
•
•
DO Term
DOID:6203 | thyroid hyalinizing trabecular adenoma
•
•
•
•
•
Publication
30504459 | J:273058
First Author: Zheng Z
Year: 2019
Journal: Blood
Title: An ATF6-tPA pathway in hepatocytes contributes to systemic fibrinolysis and is repressed by DACH1.
Volume: 133
Issue: 7
Pages: 743-753
•
•
•
•
•
Gene
291427 | Loxhd1
Type: gene
Organism: rat
•
•
•
•
•
Gene
455401 | LOXHD1
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
490467 | LOXHD1
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
784983 | LOXHD1
Type: gene
Organism: cattle
•
•
•
•
•
Gene
100150283 | loxhd1b
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
564819 | loxhd1a
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
702221 | LOXHD1
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
100487617 | loxhd1
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Publication
32657780 | J:293708
First Author: Zheng Z
Year: 2020
Journal: J Clin Invest
Title: Interacting hepatic PAI-1/tPA gene regulatory pathways influence impaired fibrinolysis severity in obesity.
Volume: 130
Issue: 8
Pages: 4348-4359
•
•
•
•
•
Author
Plat M
•
•
•
•
•
Author
Plat J
•
•
•
•
•
Publication
10469604 | -
First Author: Bateman A
Year: 1999
Journal: Curr Biol
Title: The PLAT domain: a new piece in the PKD1 puzzle.
Volume: 9
Issue: 16
Pages: R588-90
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0033458 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0033438 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0033363 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0033434 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0033148 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_97610 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0033950 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0032474 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0033123 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0033278 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0033222 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0033367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0033265 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0033969 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0032186 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0032590 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0021371 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0032019 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
2826484 | J:8978
First Author: Rickles RJ
Year: 1988
Journal: J Biol Chem
Title: Molecular cloning of complementary DNA to mouse tissue plasminogen activator mRNA and its expression during F9 teratocarcinoma cell differentiation.
Volume: 263
Issue: 3
Pages: 1563-9
•
•
•
•
•
Publication
18467699 | J:136189
First Author: Adhami F
Year: 2008
Journal: Am J Pathol
Title: Deleterious effects of plasminogen activators in neonatal cerebral hypoxia-ischemia.
Volume: 172
Issue: 6
Pages: 1704-16
•
•
•
•
•
Publication
17049177 | J:117942
First Author: Bennur S
Year: 2007
Journal: Neuroscience
Title: Stress-induced spine loss in the medial amygdala is mediated by tissue-plasminogen activator.
Volume: 144
Issue: 1
Pages: 8-16
•
•
•
•
•
Publication
25131752 | J:214826
First Author: Lin L
Year: 2014
Journal: Am J Pathol
Title: Myeloid-derived tissue-type plasminogen activator promotes macrophage motility through FAK, Rac1, and NF-κB pathways.
Volume: 184
Issue: 10
Pages: 2757-67
•
•
•
•
•
Publication
8604050 | J:110861
First Author: Frey U
Year: 1996
Journal: J Neurosci
Title: A different form of long-lasting potentiation revealed in tissue plasminogen activator mutant mice.
Volume: 16
Issue: 6
Pages: 2057-63
•
•
•
•
•
Publication
17936515 | J:130793
First Author: Lee SR
Year: 2007
Journal: Neuroscience
Title: Reduction of hippocampal cell death and proteolytic responses in tissue plasminogen activator knockout mice after transient global cerebral ischemia.
Volume: 150
Issue: 1
Pages: 50-7
•
•
•
•
•
Publication
35576527 | J:328517
First Author: Goncalves A
Year: 2022
Journal: Blood
Title: Thrombolytic tPA-induced hemorrhagic transformation of ischemic stroke is mediated by PKCβ phosphorylation of occludin.
Volume: 140
Issue: 4
Pages: 388-400
•
•
•
•
•
Publication
20156421 | J:158926
 
First Author: Pothakos K
Year: 2010
Journal: Brain Res
Title: Decreased serotonin levels associated with behavioral disinhibition in tissue plasminogen activator deficient (tPA-/-) mice.
Volume: 1326
Pages: 135-42
•
•
•
•
•
Publication
30201709 | J:266344
First Author: Xia Y
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Tissue plasminogen activator promotes white matter integrity and functional recovery in a murine model of traumatic brain injury.
Volume: 115
Issue: 39
Pages: E9230-E9238
•
•
•
•
•
Publication
7566088 | J:28943
First Author: Tsirka SE
Year: 1995
Journal: Nature
Title: Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.
Volume: 377
Issue: 6547
Pages: 340-4
•
•
•
•
•
Publication
10632583 | J:120571
First Author: Zhuo M
Year: 2000
Journal: J Neurosci
Title: Role of tissue plasminogen activator receptor LRP in hippocampal long-term potentiation.
Volume: 20
Issue: 2
Pages: 542-9
•
•
•
•
•
Publication
10216203 | J:107785
First Author: Ripley TL
Year: 1999
Journal: Brain Res
Title: Increased sensitivity to cocaine, and over-responding during cocaine self-administration in tPA knockout mice.
Volume: 826
Issue: 1
Pages: 117-27
•
•
•
•
•
Publication
23939410 | J:203861
 
First Author: Cops EJ
Year: 2013
Journal: Exp Neurol
Title: Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait.
Volume: 249
Pages: 8-19
•
•
•
•
•
Publication
15590153 | J:105225
First Author: Hennebert O
Year: 2005
Journal: Neuroscience
Title: Ontogenic study of the influence of tissue plasminogen activator (t-PA) in neonatal excitotoxic brain insult and the subsequent microglia/macrophage activation.
Volume: 130
Issue: 3
Pages: 697-712
•
•
•
•
•
Publication
19181855 | J:144953
First Author: Maiya R
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Tissue plasminogen activator modulates the cellular and behavioral response to cocaine.
Volume: 106
Issue: 6
Pages: 1983-8
•
•
•
•
•
Publication
20724593 | J:165340
First Author: Lin L
Year: 2010
Journal: Am J Pathol
Title: tPA activates LDL receptor-related protein 1-mediated mitogenic signaling involving the p90RSK and GSK3beta pathway.
Volume: 177
Issue: 4
Pages: 1687-96
•
•
•
•
•
Publication
25499620 | J:223986
 
First Author: Nakamura K
Year: 2015
Journal: Behav Brain Res
Title: Tissue plasminogen activator modulates emotion in a social context.
Volume: 281
Pages: 24-31
•
•
•
•
•
Publication
22016526 | J:317111
First Author: Bukhari N
Year: 2011
Journal: J Neurosci
Title: Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system.
Volume: 31
Issue: 42
Pages: 14931-43
•
•
•
•
•
Publication
24126163 | J:212601
First Author: Oh SB
Year: 2014
Journal: Neurobiol Aging
Title: Tissue plasminogen activator arrests Alzheimer's disease pathogenesis.
Volume: 35
Issue: 3
Pages: 511-9
•
•
•
•
•
Publication
29370799 | J:271768
First Author: Krizo JA
Year: 2018
Journal: BMC Physiol
Title: Regulation of Locomotor activity in fed, fasted, and food-restricted mice lacking tissue-type plasminogen activator.
Volume: 18
Issue: 1
Pages: 2
•
•
•
•
•
Publication
12917371 | J:84875
First Author: Seeds NW
Year: 2003
Journal: J Neurosci
Title: Absence of tissue plasminogen activator gene or activity impairs mouse cerebellar motor learning.
Volume: 23
Issue: 19
Pages: 7368-75
•
•
•
•
•
Publication
15451307 | J:93533
First Author: Kumada M
Year: 2004
Journal: Toxicol Appl Pharmacol
Title: Endogenous tissue type plasminogen activator facilitates NMDA-induced retinal damage.
Volume: 200
Issue: 1
Pages: 48-53
•
•
•
•
•
Publication
12182903 | J:120677
First Author: Pawlak R
Year: 2002
Journal: Neuroscience
Title: Rapid, specific and active site-catalyzed effect of tissue-plasminogen activator on hippocampus-dependent learning in mice.
Volume: 113
Issue: 4
Pages: 995-1001
•
•
•
•
•
Publication
10570208 | J:58684
First Author: Seeds NW
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Neuronal migration is retarded in mice lacking the tissue plasminogen activator gene.
Volume: 96
Issue: 24
Pages: 14118-23
•
•
•
•
•
Publication
8710934 | J:34823
First Author: Huang YY
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways.
Volume: 93
Issue: 16
Pages: 8699-704
•
•
•
•
•
Publication
18199803 | J:150173
First Author: Hu K
Year: 2008
Journal: J Am Soc Nephrol
Title: tPA protects renal interstitial fibroblasts and myofibroblasts from apoptosis.
Volume: 19
Issue: 3
Pages: 503-14
•
•
•
•
•
Publication
17673549 | J:123767
First Author: Norris EH
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Modulation of NR2B-regulated contextual fear in the hippocampus by the tissue plasminogen activator system.
Volume: 104
Issue: 33
Pages: 13473-8
•
•
•
•
•
Publication
11682113 | J:96450
First Author: Ripley TL
Year: 2001
Journal: Behav Brain Res
Title: Evidence for impairment of behavioural inhibition in performance of operant tasks in tPA-/- mice.
Volume: 125
Issue: 1-2
Pages: 215-27
•
•
•
•
•
Publication
15033286 | J:95936
First Author: Horwood JM
Year: 2004
Journal: Behav Brain Res
Title: Evidence for disrupted NMDA receptor function in tissue plasminogen activator knockout mice.
Volume: 150
Issue: 1-2
Pages: 127-38
•
•
•
•
•
Publication
11682111 | J:92773
First Author: Ammassari-Teule M
Year: 2001
Journal: Behav Brain Res
Title: Learning about the context in genetically-defined mice.
Volume: 125
Issue: 1-2
Pages: 195-204
•
•
•
•
•
Publication
17944888 | J:147927
First Author: Hsiao Y
Year: 2008
Journal: J Gastroenterol Hepatol
Title: Disruption of tissue-type plasminogen activator gene in mice aggravated liver fibrosis.
Volume: 23
Issue: 7 Pt 2
Pages: e258-64
•
•
•
•
•
Publication
17286591 | J:122545
First Author: Ito M
Year: 2007
Journal: J Neurochem
Title: Possible involvement of protease-activated receptor-1 in the regulation of morphine-induced dopamine release and hyperlocomotion by the tissue plasminogen activator-plasmin system.
Volume: 101
Issue: 5
Pages: 1392-9
•
•
•
•
•
Publication
21383198 | J:170087
First Author: Noel M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Tissue plasminogen activator is required for the development of fetal alcohol syndrome in mice.
Volume: 108
Issue: 12
Pages: 5069-74
•
•
•
•
•
Publication
30996120 | J:274647
First Author: Pu H
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Protease-independent action of tissue plasminogen activator in brain plasticity and neurological recovery after ischemic stroke.
Volume: 116
Issue: 18
Pages: 9115-9124
•
•
•
•
•
Publication
12270047 | J:89414
First Author: Centonze D
Year: 2002
Journal: Eur J Neurosci
Title: Tissue plasminogen activator is required for corticostriatal long-term potentiation.
Volume: 16
Issue: 4
Pages: 713-21
•
•
•
•
•
Publication
17321054 | J:122015
First Author: Leroux P
Year: 2007
Journal: Neuroscience
Title: Role of tissue-plasminogen activator (t-PA) in a mouse model of neonatal white matter lesions: interaction with plasmin inhibitors and anti-inflammatory drugs.
Volume: 146
Issue: 2
Pages: 670-8
•
•
•
•
•
Publication
21519332 | J:173193
First Author: Sashindranath M
Year: 2011
Journal: Lab Invest
Title: Compartment- and context-specific changes in tissue-type plasminogen activator (tPA) activity following brain injury and pharmacological stimulation.
Volume: 91
Issue: 7
Pages: 1079-91
•
•
•
•
•
Publication
17317018 | J:122016
First Author: Yan Y
Year: 2007
Journal: Neuroscience
Title: Reinforcing effects of morphine are reduced in tissue plasminogen activator-knockout mice.
Volume: 146
Issue: 1
Pages: 50-9
•
•
•
•
•
Publication
16410551 | J:105390
First Author: Parathath SR
Year: 2006
Journal: J Cell Sci
Title: Nitric oxide mediates neurodegeneration and breakdown of the blood-brain barrier in tPA-dependent excitotoxic injury in mice.
Volume: 119
Issue: Pt 2
Pages: 339-49
•
•
•
•
•
Publication
10762331 | J:89431
First Author: Calabresi P
Year: 2000
Journal: Eur J Neurosci
Title: Tissue plasminogen activator controls multiple forms of synaptic plasticity and memory.
Volume: 12
Issue: 3
Pages: 1002-12
•
•
•
•
•
Publication
18000864 | J:156292
First Author: Nolin WB
Year: 2008
Journal: Glia
Title: tPA-mediated generation of plasmin is catalyzed by the proteoglycan NG2.
Volume: 56
Issue: 2
Pages: 177-89
•
•
•
•
•
Publication
15659235 | J:105137
First Author: Nagai T
Year: 2005
Journal: J Neurochem
Title: The role of tissue plasminogen activator in methamphetamine-related reward and sensitization.
Volume: 92
Issue: 3
Pages: 660-7
•
•
•
•
•
Publication
20639453 | J:163467
First Author: Hao S
Year: 2010
Journal: Am J Pathol
Title: tPA is a potent mitogen for renal interstitial fibroblasts: role of beta1 integrin/focal adhesion kinase signaling.
Volume: 177
Issue: 3
Pages: 1164-75
•
•
•
•
•
Publication
16978586 | J:113092
First Author: Ling C
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Disruption of tissue plasminogen activator gene reduces macrophage migration.
Volume: 349
Issue: 3
Pages: 906-12
•
•
•
•
•
Publication
30090852 | J:265104
 
First Author: Stevenson TK
Year: 2018
Journal: eNeuro
Title: Characterization of Tissue Plasminogen Activator Expression and Trafficking in the Adult Murine Brain.
Volume: 5
Issue: 4
•
•
•
•
•
Publication
16870729 | J:111061
First Author: Li J
Year: 2006
Journal: J Neurosci
Title: Neural stem cells rescue nervous purkinje neurons by restoring molecular homeostasis of tissue plasminogen activator and downstream targets.
Volume: 26
Issue: 30
Pages: 7839-48
•
•
•
•
•
Publication
23674688 | J:197421
First Author: Li J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Tissue plasminogen activator regulates Purkinje neuron development and survival.
Volume: 110
Issue: 26
Pages: E2410-9
•
•
•
•
•
Publication
16682647 | J:110097
First Author: Li J
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Purkinje neuron degeneration in nervous (nr) mutant mice is mediated by a metabolic pathway involving excess tissue plasminogen activator.
Volume: 103
Issue: 20
Pages: 7847-52
•
•
•
•
•
Publication
14523088 | J:86823
First Author: Melchor JP
Year: 2003
Journal: J Neurosci
Title: The tissue plasminogen activator-plasminogen proteolytic cascade accelerates amyloid-beta (Abeta) degradation and inhibits Abeta-induced neurodegeneration.
Volume: 23
Issue: 26
Pages: 8867-71
•
•
•
•
•
Publication
15978259 | J:99963
First Author: Collinge JE
Year: 2005
Journal: Exp Eye Res
Title: Expression of tissue plasminogen activator during eye development.
Volume: 81
Issue: 1
Pages: 90-6
•
•
•
•
•
Publication
3123315 | J:9013
First Author: Huarte J
Year: 1987
Journal: Genes Dev
Title: Meiotic maturation of mouse oocytes triggers the translation and polyadenylation of dormant tissue-type plasminogen activator mRNA.
Volume: 1
Issue: 10
Pages: 1201-11
•
•
•
•
•
Publication
2542775 | J:27208
First Author: Rickles RJ
Year: 1989
Journal: Mol Cell Biol
Title: Differentiation-responsive elements in the 5' region of the mouse tissue plasminogen activator gene confer two-stage regulation by retinoic acid and cyclic AMP in teratocarcinoma cells.
Volume: 9
Issue: 4
Pages: 1691-704
•
•
•
•
•
Publication
8349806 | J:14180
First Author: Sappino AP
Year: 1993
Journal: J Clin Invest
Title: Extracellular proteolysis in the adult murine brain.
Volume: 92
Issue: 2
Pages: 679-85
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom