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Search results 1 to 100 out of 106 for Plekhg1

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
57480 | PLEKHG1
Type: gene
Organism: human
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Gene
100488098 | plekhg1
Type: gene
Organism: frog, western clawed
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Gene
679812 | Plekhg1
Type: gene
Organism: rat
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Gene
484035 | PLEKHG1
Type: gene
Organism: dog, domestic
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Gene
463071 | PLEKHG1
Type: gene
Organism: chimpanzee
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Gene
525772 | PLEKHG1
Type: gene
Organism: cattle
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Gene
421632 | PLEKHG1
Type: gene
Organism: chicken
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Gene
705354 | PLEKHG1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2676551 | Plekhg1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
   
Probe: MGI:6180811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191095
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Plekhg1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6180811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191095
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Plekhg1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6180811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191095
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Plekhg1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6180811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191095
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Plekhg1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6180811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191095
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Plekhg1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6180811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191095
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Plekhg1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6180811
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191095
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Plekhg1
Detected: true
Specimen Num: 7
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Gene
108348020 | LOC108348020
Type: gene
Organism: human
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Protein Coding Gene
MGP_CAROLIEiJ_G0015079 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016974 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016952 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016917 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016910 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016735 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2676551 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017373 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016317 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016707 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0016815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016810 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016890 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016841 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017410 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016103 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016378 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023698 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015884 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:6444369
Assay Type: RT-PCR
Annotation Date: 2020-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6446180
Age: postnatal week 5
Specimen Label: wild type control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6444369
Assay Type: RT-PCR
Annotation Date: 2020-07-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:6446180
Age: postnatal week 5
Specimen Label: miR-183C
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7705566
Assay Type: RT-PCR
Annotation Date: 2024-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7705982
Age: postnatal day 7
Image: S3
Specimen Label: cortex
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7705566
Assay Type: RT-PCR
Annotation Date: 2024-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Stage: TS28
Assay Id: MGI:7705982
Age: postnatal day 7
Image: S3
Specimen Label: thalamus/hypothalamus
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7705566
Assay Type: RT-PCR
Annotation Date: 2024-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Stage: TS28
Assay Id: MGI:7705982
Age: postnatal day 7
Image: S3
Specimen Label: thalamus/hypothalamus
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7705566
Assay Type: RT-PCR
Annotation Date: 2024-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7705983
Age: postnatal day 14
Image: S3
Specimen Label: cortex
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7705566
Assay Type: RT-PCR
Annotation Date: 2024-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3529528
Stage: TS28
Assay Id: MGI:7705983
Age: postnatal day 14
Image: S3
Specimen Label: (d) thalamus
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3063654
Assay Type: RNA in situ
Annotation Date: 2011-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603912
Pattern: Widespread
Stage: TS12
Assay Id: MGI:5291811
Age: embryonic day 8.0
Image: E8.0
Specimen Label: E8.0
Detected: true
Specimen Num: 1
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Publication
30578296 | J:275368
First Author: Shu P
Year: 2019
Journal: J Biol Chem
Title: The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system.
Volume: 294
Issue: 10
Pages: 3444-3453
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Publication
38912572 | J:352993
 
First Author: Krishnamurthy A
Year: 2024
Journal: Development
Title: Engrailed transcription factors direct excitatory cerebellar neuron diversity and survival.
Volume: 151
Issue: 14
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Publication
30926747 | J:275806
First Author: Wu D
Year: 2019
Journal: J Neurosci
Title: A Role for Sensory end Organ-Derived Signals in Regulating Muscle Spindle Proprioceptor Phenotype.
Volume: 39
Issue: 22
Pages: 4252-4267
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Publication
33431871 | J:301083
First Author: Huisman C
Year: 2021
Journal: Nat Commun
Title: The histone H3-lysine 4-methyltransferase Mll4 regulates the development of growth hormone-releasing hormone-producing neurons in the mouse hypothalamus.
Volume: 12
Issue: 1
Pages: 256
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Publication
22008794 | J:143778
First Author: Tamplin OJ
Year: 2011
Journal: Dev Biol
Title: Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.
Volume: 360
Issue: 2
Pages: 415-25
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Publication
23341629 | J:193822
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
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Publication
12693553 | J:83413
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q6DFV4
Organism: Mus musculus/domesticus
Length: 506  
Fragment?: true
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Protein
Q148U5
Organism: Mus musculus/domesticus
Length: 1299  
Fragment?: false
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Protein
Q148U4
Organism: Mus musculus/domesticus
Length: 1299  
Fragment?: false
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Publication
29485996 | J:259969
First Author: Wu Y
Year: 2018
Journal: PLoS One
Title: Characterization of knockin mice at the Rosa26, Tac1 and Plekhg1 loci generated by homologous recombination in oocytes.
Volume: 13
Issue: 2
Pages: e0193129
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Allele
Tg(Plekhg1-EGFP)MS27Gsat | MGI:4847320
Name: transgene insertion MS27, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:5004208 | STOCK Tg(Plekhg1-EGFP)MS27Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Publication
18045877 | -
First Author: Ueda H
Year: 2008
Journal: J Biol Chem
Title: Heterotrimeric G protein betagamma subunits stimulate FLJ00018, a guanine nucleotide exchange factor for Rac1 and Cdc42.
Volume: 283
Issue: 4
Pages: 1946-53
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Publication
19165232 | -
First Author: Otowa T
Year: 2009
Journal: J Hum Genet
Title: Genome-wide association study of panic disorder in the Japanese population.
Volume: 54
Issue: 2
Pages: 122-6
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Protein Domain
IPR043324 | PH_PLEKHG1_G2_G3
Type: Domain
Description: PLEKHG1 (also called ARHGEF41), PLEKHG2 (also called ARHGEF42 or CLG/common-site lymphoma/leukemia guanine nucleotide exchange factor2), and PLEKHG3 (also called ARHGEF43) have RhoGEF DH/double-homology domains in tandem with a PH domain which is involved in phospholipid binding. They function as a guanine nucleotide exchange factor (GEF) and are involved in the regulation of Rho protein signal transduction []. Mutations in PLEKHG1 have been associated panic disorder (PD), an anxiety disorder characterized by panic attacks and anticipatory anxiety [].PH domains have diverse functions, but in general are involved in targeting proteins to the appropriate cellular location or in the interaction with a binding partner. They share little sequence conservation, but all have a common fold, which is electrostatically polarized. Less than 10% of PH domains bind phosphoinositide phosphates (PIPs) with high affinity and specificity. PH domains are distinguished from other PIP-binding domains by their specific high-affinity binding to PIPs with two vicinal phosphate groups: PtdIns(3,4)P2, PtdIns(4,5)P2 or PtdIns(3,4,5)P3 which results in targeting some PH domain proteins to the plasma membrane []. A few display strong specificity in lipid binding. Any specificity is usually determined by loop regions or insertions in the N terminus of the domain, which are not conserved across all PH domains. PH domains are found in cellular signaling proteins such as serine/threonine kinase, tyrosine kinases, regulators of G-proteins, endocytotic GTPases, adaptors, as well as cytoskeletal associated molecules and in lipid associated enzymes.
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Protein
Q4VAC9
Organism: Mus musculus/domesticus
Length: 1341  
Fragment?: false
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Protein
Q6KAU7
Organism: Mus musculus/domesticus
Length: 1340  
Fragment?: false
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Protein
F7C583
Organism: Mus musculus/domesticus
Length: 1213  
Fragment?: true
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Protein
F6S200
Organism: Mus musculus/domesticus
Length: 1446  
Fragment?: true
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Protein
A0A5F8MPP0
Organism: Mus musculus/domesticus
Length: 1465  
Fragment?: false
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Protein
Q80TH7
Organism: Mus musculus/domesticus
Length: 1220  
Fragment?: true
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Protein
D3Z5N8
Organism: Mus musculus/domesticus
Length: 1365  
Fragment?: false
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Protein
A0A0R4J1S3
Organism: Mus musculus/domesticus
Length: 912  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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