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Search results 1 to 100 out of 862 for Plk1

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
5347 | PLK1
Type: gene
Organism: human
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Gene
538238 | PLK1
Type: gene
Organism: cattle
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Gene
416575 | PLK1
Type: gene
Organism: chicken
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Gene
280649 | plk1
Type: gene
Organism: zebrafish
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Gene
697686 | PLK1
Type: gene
Organism: macaque, rhesus
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Gene
407937 | plk1
Type: gene
Organism: frog, western clawed
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Gene
25515 | Plk1
Type: gene
Organism: rat
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Gene
489971 | PLK1
Type: gene
Organism: dog, domestic
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Gene
453991 | PLK1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:97621 | Plk1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:7572382
Assay Type: RNA in situ
Annotation Date: 2024-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603916
Pattern: Widespread
Stage: TS16
Assay Id: MGI:7572397
Age: embryonic day 10.0
Note: Authors report that all candidate genes are broadly expressed in embryo.
Specimen Label: 3E Plk1
Detected: true
Specimen Num: 1
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Publication
25658810 | J:229046
First Author: Solc P
Year: 2015
Journal: PLoS One
Title: Multiple requirements of PLK1 during mouse oocyte maturation.
Volume: 10
Issue: 2
Pages: e0116783
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Publication
18794363 | J:142593
First Author: Lu LY
Year: 2008
Journal: Mol Cell Biol
Title: Polo-like kinase 1 is essential for early embryonic development and tumor suppression.
Volume: 28
Issue: 22
Pages: 6870-6
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Publication
35950917 | J:330133
First Author: Zhang Z
Year: 2022
Journal: Cancer Res
Title: Targeting Plk1 Sensitizes Pancreatic Cancer to Immune Checkpoint Therapy.
Volume: 82
Issue: 19
Pages: 3532-3548
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Gene
136647 | MPLKIP
Type: gene
Organism: human
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Publication
22554510 | J:184525
First Author: Sun SC
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Survivin regulates Plk1 localization to kinetochore in mouse oocyte meiosis.
Volume: 421
Issue: 4
Pages: 797-800
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Publication
29549256 | J:260746
First Author: Raab M
Year: 2018
Journal: Nat Commun
Title: PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells.
Volume: 9
Issue: 1
Pages: 1106
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Publication
33376114 | J:304051
First Author: Gheghiani L
Year: 2021
Journal: Cancer Res
Title: PLK1 Induces Chromosomal Instability and Overrides Cell-Cycle Checkpoints to Drive Tumorigenesis.
Volume: 81
Issue: 5
Pages: 1293-1307
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Publication
8099445 | J:12876
First Author: Clay FJ
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Identification and cloning of a protein kinase-encoding mouse gene, Plk, related to the polo gene of Drosophila.
Volume: 90
Issue: 11
Pages: 4882-6
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Publication
8018557 | J:20466
First Author: Hamanaka R
Year: 1994
Journal: Cell Growth Differ
Title: Cloning and characterization of human and murine homologues of the Drosophila polo serine-threonine kinase.
Volume: 5
Issue: 3
Pages: 249-57
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Publication
7902533 | J:28603
First Author: Lake RJ
Year: 1993
Journal: Mol Cell Biol
Title: Cell cycle- and terminal differentiation-associated regulation of the mouse mRNA encoding a conserved mitotic protein kinase.
Volume: 13
Issue: 12
Pages: 7793-801
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Publication
12784245 | J:83770
First Author: Anger M
Year: 2003
Journal: Mol Reprod Dev
Title: Cell cycle dependent expression of Plk1 in synchronized porcine fetal fibroblasts.
Volume: 65
Issue: 3
Pages: 245-53
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Publication
24142876 | J:202921
First Author: Ragland RL
Year: 2013
Journal: Genes Dev
Title: RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells.
Volume: 27
Issue: 20
Pages: 2259-73
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Publication
38201556 | J:344313
 
First Author: Liao Z
Year: 2023
Journal: Cancers (Basel)
Title: Increased hsa-miR-100-5p Expression Improves Hepatocellular Carcinoma Prognosis in the Asian Population with PLK1 Variant rs27770A>G.
Volume: 16
Issue: 1
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Publication
26259146 | J:339375
 
First Author: Lee HS
Year: 2015
Journal: Nat Commun
Title: The chromatin remodeller RSF1 is essential for PLK1 deposition and function at mitotic kinetochores.
Volume: 6
Pages: 7904
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Publication
35546066 | J:325537
 
First Author: Dong MZ
Year: 2022
Journal: Development
Title: PPP4C facilitates homologous recombination DNA repair by dephosphorylating PLK1 during early embryo development.
Volume: 149
Issue: 10
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Publication
33615678 | J:314448
First Author: Wellard SR
Year: 2021
Journal: EMBO Rep
Title: Overlapping roles for PLK1 and Aurora A during meiotic centrosome biogenesis in mouse spermatocytes.
Volume: 22
Issue: 4
Pages: e51023
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Publication
32267211 | J:291160
First Author: Little TM
Year: 2020
Journal: Mol Biol Cell
Title: PLK1 is required for chromosome compaction and microtubule organization in mouse oocytes.
Volume: 31
Issue: 12
Pages: 1206-1217
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Publication
35274968 | J:328688
First Author: Wellard SR
Year: 2022
Journal: Mol Biol Cell
Title: PLK1 depletion alters homologous recombination and synaptonemal complex disassembly events during mammalian spermatogenesis.
Volume: 33
Issue: 5
Pages: ar37
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Publication
31101859 | J:279021
First Author: Rezey AC
Year: 2019
Journal: Sci Rep
Title: Plk1 Mediates Paxillin Phosphorylation (Ser-272), Centrosome Maturation, and Airway Smooth Muscle Layer Thickening in Allergic Asthma.
Volume: 9
Issue: 1
Pages: 7555
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Publication
33615693 | J:333218
First Author: Alfaro E
Year: 2021
Journal: EMBO Rep
Title: PLK1 regulates centrosome migration and spindle dynamics in male mouse meiosis.
Volume: 22
Issue: 4
Pages: e51030
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Publication
28692064 | J:250969
First Author: de Cárcer G
Year: 2017
Journal: Nat Med
Title: Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis.
Volume: 23
Issue: 8
Pages: 964-974
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Gene
401296 | LNCRI
Type: gene
Organism: human
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Publication
28935709 | J:245932
First Author: Wang H
Year: 2017
Journal: Development
Title: CIP2A acts as a scaffold for CEP192-mediated microtubule organizing center assembly by recruiting Plk1 and aurora A during meiotic maturation.
Volume: 144
Issue: 20
Pages: 3829-3839
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Publication
28794108 | J:261919
First Author: Severance AL
Year: 2017
Journal: Am J Physiol Cell Physiol
Title: PLK1 regulates spindle association of phosphorylated eukaryotic translation initiation factor 4E-binding protein and spindle function in mouse oocytes.
Volume: 313
Issue: 5
Pages: C501-C515
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Publication
22405274 | J:183245
First Author: Mondal G
Year: 2012
Journal: Mol Cell
Title: Tex14, a Plk1-regulated protein, is required for kinetochore-microtubule attachment and regulation of the spindle assembly checkpoint.
Volume: 45
Issue: 5
Pages: 680-95
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Publication
35981705 | J:327823
First Author: Hu HJ
Year: 2022
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: PLK1 promotes cholesterol efflux and alleviates atherosclerosis by up-regulating ABCA1 and ABCG1 expression via the AMPK/PPARγ/LXRα pathway.
Volume: 1867
Issue: 12
Pages: 159221
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Publication
26654596 | J:231483
First Author: Du J
Year: 2015
Journal: Cell Cycle
Title: Unique subcellular distribution of phosphorylated Plk1 (Ser137 and Thr210) in mouse oocytes during meiotic division and pPlk1(Ser137) involvement in spindle formation and REC8 cleavage.
Volume: 14
Issue: 22
Pages: 3566-79
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Publication
25533956 | J:216866
First Author: Kim J
Year: 2015
Journal: Nature
Title: Meikin is a conserved regulator of meiosis-I-specific kinetochore function.
Volume: 517
Issue: 7535
Pages: 466-71
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Publication
27979967 | J:239231
First Author: Zhang B
Year: 2017
Journal: J Biol Chem
Title: DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle.
Volume: 292
Issue: 4
Pages: 1351-1360
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Gene
700381 | LOC700381
Type: gene
Organism: macaque, rhesus
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Publication
25049273 | J:215833
First Author: Kushner EJ
Year: 2014
Journal: J Cell Biol
Title: Excess centrosomes disrupt endothelial cell migration via centrosome scattering.
Volume: 206
Issue: 2
Pages: 257-72
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Publication
21772266 | J:261412
 
First Author: Raab M
Year: 2011
Journal: Nat Commun
Title: Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells.
Volume: 2
Pages: 395
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Publication
27417127 | J:235197
 
First Author: Wachowicz P
Year: 2016
Journal: Bioessays
Title: Genetic depletion of Polo-like kinase 1 leads to embryonic lethality due to mitotic aberrancies.
Volume: 38 Suppl 1
Pages: S96-S106
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Publication
26185128 | J:230257
First Author: Trakala M
Year: 2015
Journal: Blood
Title: Activation of the endomitotic spindle assembly checkpoint and thrombocytopenia in Plk1-deficient mice.
Volume: 126
Issue: 14
Pages: 1707-14
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Publication
23649868 | J:199476
First Author: Baran V
Year: 2013
Journal: Mol Reprod Dev
Title: Polo-like kinase 1 is essential for the first mitotic division in the mouse embryo.
Volume: 80
Issue: 7
Pages: 522-34
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Publication
7576608 | J:27461
First Author: Matsubara N
Year: 1995
Journal: Mol Reprod Dev
Title: Murine polo like kinase 1 gene is expressed in meiotic testicular germ cells and oocytes.
Volume: 41
Issue: 4
Pages: 407-15
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Publication
9914375 | J:52815
First Author: Wianny F
Year: 1998
Journal: Chromosoma
Title: Mouse polo-like kinase 1 associates with the acentriolar spindle poles, meiotic chromosomes and spindle midzone during oocyte maturation.
Volume: 107
Issue: 6-7
Pages: 430-9
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Publication
20655883 | J:166294
First Author: Tyagi S
Year: 2010
Journal: Biochem Pharmacol
Title: Polo-like kinase1 (Plk1) knockdown enhances cisplatin chemosensitivity via up-regulation of p73α in p53 mutant human epidermoid squamous carcinoma cells.
Volume: 80
Issue: 9
Pages: 1326-34
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Publication
28900036 | J:246807
First Author: Li Z
Year: 2017
Journal: J Biol Chem
Title: Polo-like kinase 1 (Plk1) overexpression enhances ionizing radiation-induced cancer formation in mice.
Volume: 292
Issue: 42
Pages: 17461-17472
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Publication
28851945 | J:255797
First Author: Ajduk A
Year: 2017
Journal: Sci Rep
Title: Delayed APC/C activation extends the first mitosis of mouse embryos.
Volume: 7
Issue: 1
Pages: 9682
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Publication
21637952 | J:281562
First Author: Xiong F
Year: 2012
Journal: Mol Biol Rep
Title: Plk1-mediated phosphorylation of UAP56 regulates the stability of UAP56.
Volume: 39
Issue: 2
Pages: 1935-42
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Publication
27773673 | J:249255
First Author: Xiao D
Year: 2016
Journal: Mol Cell
Title: Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
Volume: 64
Issue: 3
Pages: 493-506
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Publication
27662907 | J:237359
First Author: Li J
Year: 2016
Journal: J Biol Chem
Title: Polo-like Kinase 1 Regulates Vimentin Phosphorylation at Ser-56 and Contraction in Smooth Muscle.
Volume: 291
Issue: 45
Pages: 23693-23703
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Publication
17342725 | J:128733
First Author: Zhang Z
Year: 2007
Journal: Mol Reprod Dev
Title: Polo-like kinase 1 may regulate G2/M transition of mouse fertilized eggs by means of inhibiting the phosphorylation of Tyr 15 of Cdc2.
Volume: 74
Issue: 10
Pages: 1247-54
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Publication
28286049 | J:240675
First Author: Shirakawa J
Year: 2017
Journal: Cell Metab
Title: Insulin Signaling Regulates the FoxM1/PLK1/CENP-A Pathway to Promote Adaptive Pancreatic β Cell Proliferation.
Volume: 25
Issue: 4
Pages: 868-882.e5
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Publication
31393265 | J:278542
   
First Author: Jia Z
Year: 2019
Journal: Elife
Title: A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration.
Volume: 8
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Publication
21245198 | J:182879
First Author: Castiel A
Year: 2011
Journal: J Cell Sci
Title: The Stil protein regulates centrosome integrity and mitosis through suppression of Chfr.
Volume: 124
Issue: Pt 4
Pages: 532-9
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Publication
18022836 | J:132402
First Author: Yu A
Year: 2008
Journal: Mol Reprod Dev
Title: Regulation of cAMP on the first mitotic cell cycle of mouse embryos.
Volume: 75
Issue: 3
Pages: 489-95
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Publication
31545409 | J:298732
First Author: Hu H
Year: 2019
Journal: Mol Med Rep
Title: Phospho‑regulation of Cdc14A by polo‑like kinase 1 is involved in β‑cell function and cell cycle regulation.
Volume: 20
Issue: 5
Pages: 4277-4284
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Publication
18331714 | J:204810
First Author: Wang X
Year: 2008
Journal: Dev Cell
Title: sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1.
Volume: 14
Issue: 3
Pages: 331-41
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Publication
23455152 | J:195306
First Author: Yeh TY
Year: 2013
Journal: EMBO J
Title: Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit.
Volume: 32
Issue: 7
Pages: 1023-35
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Publication
29269218 | J:257912
First Author: Feitosa WB
Year: 2018
Journal: Dev Biol
Title: Temporal and SUMO-specific SUMOylation contribute to the dynamics of Polo-like kinase 1 (PLK1) and spindle integrity during mouse oocyte meiosis.
Volume: 434
Issue: 2
Pages: 278-291
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Publication
9370299 | J:36971
First Author: Clay FJ
Year: 1997
Journal: Gene
Title: The mouse Plk gene: structural characterization, chromosomal localization and identification of a processed Plk pseudogene.
Volume: 198
Issue: 1-2
Pages: 329-39
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Publication
29191835 | J:320154
First Author: Lee KH
Year: 2018
Journal: J Biol Chem
Title: Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions.
Volume: 293
Issue: 3
Pages: 847-862
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Publication
32232159 | J:289957
First Author: Guan Y
Year: 2020
Journal: Sci Adv
Title: SKP1 drives the prophase I to metaphase I transition during male meiosis.
Volume: 6
Issue: 13
Pages: eaaz2129
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Publication
22609948 | J:200479
First Author: Lee KH
Year: 2012
Journal: EMBO J
Title: Identification of a novel Wnt5a-CK1É›-Dvl2-Plk1-mediated primary cilia disassembly pathway.
Volume: 31
Issue: 14
Pages: 3104-17
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Publication
24498222 | J:212776
First Author: Ward A
Year: 2014
Journal: PLoS One
Title: p53-Dependent and cell specific epigenetic regulation of the polo-like kinases under oxidative stress.
Volume: 9
Issue: 1
Pages: e87918
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Publication
33106477 | J:314146
First Author: Gao W
Year: 2020
Journal: Cell Death Dis
Title: Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis.
Volume: 11
Issue: 10
Pages: 919
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Publication
22854038 | J:199766
First Author: Jordan PW
Year: 2012
Journal: J Cell Sci
Title: Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes.
Volume: 125
Issue: Pt 21
Pages: 5061-72
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Publication
27624071 | J:238129
First Author: Treekitkarnmongkol W
Year: 2016
Journal: Carcinogenesis
Title: Aurora kinase-A overexpression in mouse mammary epithelium induces mammary adenocarcinomas harboring genetic alterations shared with human breast cancer.
Volume: 37
Issue: 12
Pages: 1180-1189
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Publication
22479190 | J:183605
First Author: Sakai D
Year: 2012
Journal: PLoS Genet
Title: Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells.
Volume: 8
Issue: 3
Pages: e1002566
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Protein Coding Gene
MGP_CAROLIEiJ_G0030419 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032953 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032936 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032868 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032941 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032651 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97621 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033447 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031979 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032776 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032729 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032870 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032761 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033467 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031687 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032092 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013629 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0031533 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
7478607 | J:29660
First Author: Bräuninger A
Year: 1995
Journal: Oncogene
Title: Identification and functional characterization of the human and murine polo-like kinase (Plk) promoter.
Volume: 11
Issue: 9
Pages: 1793-800
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Publication
8524282 | J:29838
First Author: Lee KS
Year: 1995
Journal: Mol Cell Biol
Title: Plk is an M-phase-specific protein kinase and interacts with a kinesin-like protein, CHO1/MKLP-1.
Volume: 15
Issue: 12
Pages: 7143-51
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Publication
37879229 | J:342377
First Author: Gao Z
Year: 2023
Journal: Int Immunopharmacol
Title: Polo-like kinase 1 promotes sepsis-induced myocardial dysfunction.
Volume: 125
Issue: Pt A
Pages: 111074
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GXD Expression
GXD Expression
     
Probe: MGI:3831317
Assay Type: RT-PCR
Annotation Date: 2009-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3831318
Age: embryonic day 3.5
Specimen Label: +/-
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3831317
Assay Type: RT-PCR
Annotation Date: 2009-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3831318
Age: embryonic day 3.5
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3831317
Assay Type: RT-PCR
Annotation Date: 2009-02-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360633
Stage: TS03
Assay Id: MGI:3831318
Age: embryonic day 3.5
Specimen Label: -/-
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3831317
Assay Type: RT-PCR
Annotation Date: 2009-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3831318
Age: embryonic day 3.5
Specimen Label: +/+
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3831317
Assay Type: RT-PCR
Annotation Date: 2009-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3831318
Age: embryonic day 3.5
Specimen Label: +/-
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3831317
Assay Type: RT-PCR
Annotation Date: 2009-02-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3831318
Age: embryonic day 3.5
Specimen Label: +/-
Detected: true
Specimen Num: 6
•
•
•
•
•




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