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Search results 1 to 100 out of 515 for Pln

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Type Details Score
Gene
5350 | PLN
Type: gene
Organism: human
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Gene
100125240 | PLN
Type: gene
Organism: cattle
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Gene
100613044 | PLN
Type: gene
Organism: chimpanzee
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Gene
396378 | PLN
Type: gene
Organism: chicken
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Gene
100426104 | PLN
Type: gene
Organism: macaque, rhesus
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Gene
100379739 | pln
Type: gene
Organism: frog, western clawed
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Gene
64672 | Pln
Type: gene
Organism: rat
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Gene
414755 | PLN
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:97622 | Pln
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
32555305 | J:292111
First Author: Eijgenraam TR
Year: 2020
Journal: Sci Rep
Title: The phospholamban p.(Arg14del) pathogenic variant leads to cardiomyopathy with heart failure and is unreponsive to standard heart failure therapy.
Volume: 10
Issue: 1
Pages: 9819
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Publication
34462437 | J:309190
First Author: Grote Beverborg N
Year: 2021
Journal: Nat Commun
Title: Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy.
Volume: 12
Issue: 1
Pages: 5180
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Publication
36375644 | J:332025
 
First Author: Rogalska ME
Year: 2023
Journal: Metabolism
Title: Isoform changes of action potential regulators in the ventricles of arrhythmogenic phospholamban-R14del humanized mouse hearts.
Volume: 138
Pages: 155344
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Publication
15059971 | J:127873
First Author: Song Q
Year: 2004
Journal: FASEB J
Title: Overexpression of phospholamban in slow-twitch skeletal muscle is associated with depressed contractile function and muscle remodeling.
Volume: 18
Issue: 9
Pages: 974-6
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Publication
37955153 | J:345847
First Author: Stege NM
Year: 2023
Journal: Circ Res
Title: DWORF Extends Life Span in a PLN-R14del Cardiomyopathy Mouse Model by Reducing Abnormal Sarcoplasmic Reticulum Clusters.
Volume: 133
Issue: 12
Pages: 1006-1021
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Publication
26035394 | J:224766
First Author: Fajardo VA
Year: 2015
Journal: Dis Model Mech
Title: Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype.
Volume: 8
Issue: 8
Pages: 999-1009
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Publication
38334971 | J:345725
First Author: Stege NM
Year: 2024
Journal: Am J Physiol Heart Circ Physiol
Title: Deletion of DWORF does not affect cardiac function in aging and in PLN-R14del cardiomyopathy.
Volume: 326
Issue: 3
Pages: H870-H876
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Publication
28278204 | J:245415
First Author: Fajardo VA
Year: 2017
Journal: PLoS One
Title: Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice.
Volume: 12
Issue: 3
Pages: e0173708
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Allele
Pln<tm1.1Crcg> | MGI:6449103
Name: phospholamban; targeted mutation 1.1, Cardiovascular Research Center Groningen
Allele Type: Targeted
Attribute String: Humanized sequence
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Publication
34204946 | J:333047
 
First Author: Haghighi K
Year: 2021
Journal: J Pers Med
Title: Impaired Right Ventricular Calcium Cycling Is an Early Risk Factor in R14del-Phospholamban Arrhythmias.
Volume: 11
Issue: 6
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Publication
12610310 | J:82353
First Author: Schmitt JP
Year: 2003
Journal: Science
Title: Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban.
Volume: 299
Issue: 5611
Pages: 1410-3
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Publication
27992596 | J:243949
First Author: Kaneko M
Year: 2016
Journal: PLoS One
Title: Phospholamban Ablation Using CRISPR/Cas9 System Improves Mortality in a Murine Heart Failure Model.
Volume: 11
Issue: 12
Pages: e0168486
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Publication
23800848 | J:201527
First Author: Rajan S
Year: 2013
Journal: Physiol Genomics
Title: Microarray analysis of active cardiac remodeling genes in a familial hypertrophic cardiomyopathy mouse model rescued by a phospholamban knockout.
Volume: 45
Issue: 17
Pages: 764-73
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Publication
30601702 | J:274295
First Author: Gamu D
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: Phospholamban deficiency does not alter skeletal muscle SERCA pumping efficiency or predispose mice to diet-induced obesity.
Volume: 316
Issue: 3
Pages: E432-E442
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Publication
19139388 | J:166203
First Author: Schmitt JP
Year: 2009
Journal: Circulation
Title: Alterations of phospholamban function can exhibit cardiotoxic effects independent of excessive sarcoplasmic reticulum Ca2+-ATPase inhibition.
Volume: 119
Issue: 3
Pages: 436-44
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Publication
16476846 | J:129182
First Author: Zhao W
Year: 2006
Journal: Circulation
Title: The presence of Lys27 instead of Asn27 in human phospholamban promotes sarcoplasmic reticulum Ca2+-ATPase superinhibition and cardiac remodeling.
Volume: 113
Issue: 7
Pages: 995-1004
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Publication
21266500 | J:174649
First Author: Wang HS
Year: 2011
Journal: Physiol Genomics
Title: SERCA2a superinhibition by human phospholamban triggers electrical and structural remodeling in mouse hearts.
Volume: 43
Issue: 7
Pages: 357-64
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Publication
16413575 | J:105828
First Author: Wu Y
Year: 2006
Journal: J Mol Cell Cardiol
Title: Suppression of dynamic Ca(2+) transient responses to pacing in ventricular myocytes from mice with genetic calmodulin kinase II inhibition.
Volume: 40
Issue: 2
Pages: 213-23
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Publication
17038644 | J:129089
First Author: Li J
Year: 2006
Journal: Circ Res
Title: Calmodulin kinase II inhibition shortens action potential duration by upregulation of K+ currents.
Volume: 99
Issue: 10
Pages: 1092-9
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Publication
26966065 | J:234551
First Author: Nakagawa T
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Phospholamban degradation is induced by phosphorylation-mediated ubiquitination and inhibited by interaction with cardiac type Sarco(endo)plasmic reticulum Ca(2+)-ATPase.
Volume: 472
Issue: 3
Pages: 523-30
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Publication
25870184 | J:258761
First Author: Bibli SI
Year: 2015
Journal: Cardiovasc Res
Title: Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway.
Volume: 106
Issue: 3
Pages: 432-42
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Publication
38493225 | J:346446
First Author: Klocke B
Year: 2024
Journal: Sci Rep
Title: A novel role for phospholamban in the thalamic reticular nucleus.
Volume: 14
Issue: 1
Pages: 6376
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Publication
19920172 | J:155565
First Author: Zhao W
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The anti-apoptotic protein HAX-1 is a regulator of cardiac function.
Volume: 106
Issue: 49
Pages: 20776-81
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Publication
34024116 | J:314571
First Author: Raad N
Year: 2021
Journal: Circulation
Title: Arrhythmia Mechanism and Dynamics in a Humanized Mouse Model of Inherited Cardiomyopathy Caused by Phospholamban R14del Mutation.
Volume: 144
Issue: 6
Pages: 441-454
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Publication
21840315 | J:178357
First Author: Gaffin RD
Year: 2011
Journal: J Mol Cell Cardiol
Title: Long-term rescue of a familial hypertrophic cardiomyopathy caused by a mutation in the thin filament protein, tropomyosin, via modulation of a calcium cycling protein.
Volume: 51
Issue: 5
Pages: 812-20
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Publication
22155237 | J:183649
First Author: Haghighi K
Year: 2012
Journal: J Mol Cell Cardiol
Title: The human phospholamban Arg14-deletion mutant localizes to plasma membrane and interacts with the Na/K-ATPase.
Volume: 52
Issue: 3
Pages: 773-82
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Publication
16516179 | J:133762
First Author: Valverde CA
Year: 2006
Journal: Cardiovasc Res
Title: Phospholamban phosphorylation sites enhance the recovery of intracellular Ca2+ after perfusion arrest in isolated, perfused mouse heart.
Volume: 70
Issue: 2
Pages: 335-45
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Publication
18359893 | J:136059
First Author: Werdich AA
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Differential effects of phospholamban and Ca2+/calmodulin-dependent kinase II on [Ca2+]i transients in cardiac myocytes at physiological stimulation frequencies.
Volume: 294
Issue: 5
Pages: H2352-62
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Publication
33111944 | J:300017
First Author: Fu M
Year: 2020
Journal: Biochem J
Title: Phospholamban and sarcolipin prevent thermal inactivation of sarco(endo)plasmic reticulum Ca2+-ATPases.
Volume: 477
Issue: 21
Pages: 4281-4294
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Publication
20833651 | J:186041
First Author: Shanmugam M
Year: 2011
Journal: Cardiovasc Res
Title: Ablation of phospholamban and sarcolipin results in cardiac hypertrophy and decreased cardiac contractility.
Volume: 89
Issue: 2
Pages: 353-61
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Publication
30733280 | J:272982
 
First Author: Niemeyer J
Year: 2019
Journal: EMBO Rep
Title: The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban.
Volume: 20
Issue: 3
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Publication
23856523 | J:213362
First Author: Bai Y
Year: 2013
Journal: Circ Res
Title: Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice.
Volume: 113
Issue: 5
Pages: 517-26
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Publication
16861697 | J:116316
First Author: Yang Y
Year: 2006
Journal: Am J Physiol Heart Circ Physiol
Title: Calmodulin kinase II inhibition protects against myocardial cell apoptosis in vivo.
Volume: 291
Issue: 6
Pages: H3065-75
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Publication
19959778 | J:170053
First Author: Zhang T
Year: 2010
Journal: Circ Res
Title: Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice.
Volume: 106
Issue: 2
Pages: 354-62
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Publication
17241641 | J:121383
First Author: Vafiadaki E
Year: 2007
Journal: J Mol Biol
Title: Phospholamban interacts with HAX-1, a mitochondrial protein with anti-apoptotic function.
Volume: 367
Issue: 1
Pages: 65-79
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Publication
29068413 | J:319277
 
First Author: Yokoe S
Year: 2017
Journal: Int J Mol Sci
Title: Phospholamban Is Downregulated by pVHL-Mediated Degradation through Oxidative Stress in Failing Heart.
Volume: 18
Issue: 11
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GXD Expression
GXD Expression
   
Probe: MGI:5493045
Assay Type: RT-PCR
Annotation Date: 2013-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:5493276
Age: embryonic day 3.5
Image: 3
Specimen Label: d4.0 Pln
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5493045
Assay Type: RT-PCR
Annotation Date: 2013-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:5493276
Age: embryonic day 4.0
Image: 3
Specimen Label: d4.5 Pln
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:5800504
Assay Type: RT-PCR
Annotation Date: 2016-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3552328
Stage: TS28
Assay Id: MGI:5800519
Age: postnatal
Specimen Label: WT pLN
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5800505
Assay Type: RT-PCR
Annotation Date: 2016-10-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3552328
Stage: TS28
Assay Id: MGI:5800522
Age: postnatal
Specimen Label: WT pLN
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5800506
Assay Type: RT-PCR
Annotation Date: 2016-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3552328
Stage: TS28
Assay Id: MGI:5800523
Age: postnatal
Specimen Label: WT pLN
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5800516
Assay Type: RT-PCR
Annotation Date: 2016-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3552328
Stage: TS28
Assay Id: MGI:5800524
Age: postnatal
Specimen Label: WT pLN
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:5800514
Assay Type: RT-PCR
Annotation Date: 2016-10-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3552328
Stage: TS28
Assay Id: MGI:5800525
Age: postnatal
Specimen Label: WT pLN
Detected: true
Specimen Num: 3
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Publication
30299255 | J:274777
   
First Author: Makarewich CA
Year: 2018
Journal: Elife
Title: The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy.
Volume: 7
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Publication
24892712 | J:213804
First Author: Okumura S
Year: 2014
Journal: J Clin Invest
Title: Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses.
Volume: 124
Issue: 6
Pages: 2785-801
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Publication
26075818 | J:225429
First Author: Xie L
Year: 2015
Journal: J Clin Invest
Title: PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban.
Volume: 125
Issue: 7
Pages: 2759-71
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Publication
12639992 | J:82521
First Author: Song Q
Year: 2003
Journal: J Clin Invest
Title: Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy.
Volume: 111
Issue: 6
Pages: 859-67
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Publication
16461894 | J:106044
First Author: Gramolini AO
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Cardiac-specific overexpression of sarcolipin in phospholamban null mice impairs myocyte function that is restored by phosphorylation.
Volume: 103
Issue: 7
Pages: 2446-51
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Publication
32873725 | J:296128
 
First Author: Menzel J
Year: 2020
Journal: Sci Signal
Title: 14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban.
Volume: 13
Issue: 647
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Publication
25640239 | J:217579
First Author: Anderson DM
Year: 2015
Journal: Cell
Title: A micropeptide encoded by a putative long noncoding RNA regulates muscle performance.
Volume: 160
Issue: 4
Pages: 595-606
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Publication
30169578 | J:291512
First Author: Valverde CA
Year: 2019
Journal: Cardiovasc Res
Title: Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca2+/calmodulin kinase II constitutive phosphorylation of ryanodine receptors.
Volume: 115
Issue: 3
Pages: 556-569
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Publication
22796260 | J:186692
First Author: Wu Y
Year: 2012
Journal: J Mol Cell Cardiol
Title: CaMKII effects on inotropic but not lusitropic force frequency responses require phospholamban.
Volume: 53
Issue: 3
Pages: 429-36
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Publication
18007024 | J:141557
First Author: Zhang YH
Year: 2008
Journal: Circ Res
Title: Reduced phospholamban phosphorylation is associated with impaired relaxation in left ventricular myocytes from neuronal NO synthase-deficient mice.
Volume: 102
Issue: 2
Pages: 242-9
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Publication
15201433 | J:91410
First Author: Asahi M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice.
Volume: 101
Issue: 25
Pages: 9199-204
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Publication
26695843 | J:291966
First Author: Mazzocchi G
Year: 2016
Journal: J Physiol
Title: Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814.
Volume: 594
Issue: 11
Pages: 3005-30
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Publication
30118340 | J:271885
First Author: Law ML
Year: 2018
Journal: Am J Physiol Heart Circ Physiol
Title: Exacerbation of dystrophic cardiomyopathy by phospholamban deficiency mediated chronically increased cardiac Ca2+ cycling in vivo.
Volume: 315
Issue: 6
Pages: H1544-H1552
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Publication
24949568 | J:243767
 
First Author: Di Carlo MN
Year: 2014
Journal: J Mol Cell Cardiol
Title: CaMKII-dependent phosphorylation of cardiac ryanodine receptors regulates cell death in cardiac ischemia/reperfusion injury.
Volume: 74
Pages: 274-83
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Protein Coding Gene
MGP_CAROLIEiJ_G0015319 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017229 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017205 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017164 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017166 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0016988 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97622 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0017625 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016562 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0016961 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017066 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017060 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017141 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017089 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0017660 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016343 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0016627 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030736 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016128 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1394867 | J:3416
First Author: Ganim JR
Year: 1992
Journal: Circ Res
Title: Mouse phospholamban gene expression during development in vivo and in vitro.
Volume: 71
Issue: 5
Pages: 1021-30
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Publication
10988285 | J:66084
First Author: Chu G
Year: 2000
Journal: J Biol Chem
Title: A single site (Ser16) phosphorylation in phospholamban is sufficient in mediating its maximal cardiac responses to beta -agonists.
Volume: 275
Issue: 49
Pages: 38938-43
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Publication
15158139 | J:128873
First Author: Janczewski AM
Year: 2004
Journal: Cardiovasc Res
Title: Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model.
Volume: 62
Issue: 3
Pages: 468-80
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Publication
11306600 | J:134706
First Author: Freeman K
Year: 2001
Journal: J Clin Invest
Title: Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy.
Volume: 107
Issue: 8
Pages: 967-74
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Publication
8567978 | J:135899
First Author: Kadambi VJ
Year: 1996
Journal: J Clin Invest
Title: Cardiac-specific overexpression of phospholamban alters calcium kinetics and resultant cardiomyocyte mechanics in transgenic mice.
Volume: 97
Issue: 2
Pages: 533-9
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Publication
9468536 | J:119619
First Author: Luo W
Year: 1998
Journal: J Biol Chem
Title: Transgenic approaches to define the functional role of dual site phospholamban phosphorylation.
Volume: 273
Issue: 8
Pages: 4734-9
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Publication
32210830 | J:307837
 
First Author: Chowdhury SAK
Year: 2020
Journal: Front Physiol
Title: Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response.
Volume: 11
Pages: 107
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Publication
11115498 | J:118919
First Author: Sato Y
Year: 2001
Journal: J Biol Chem
Title: Rescue of contractile parameters and myocyte hypertrophy in calsequestrin overexpressing myocardium by phospholamban ablation.
Volume: 276
Issue: 12
Pages: 9392-9
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Publication
8062415 | J:39745
First Author: Luo W
Year: 1994
Journal: Circ Res
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Title: Phospholamban is present in endothelial cells and modulates endothelium-dependent relaxation. Evidence from phospholamban gene-ablated mice.
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Title: Combined phospholamban ablation and SERCA1a overexpression result in a new hyperdynamic cardiac state.
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Title: Phospholamban regulation of bladder contractility: evidence from gene-altered mouse models.
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Title: Phospholamban regulates nuclear Ca2+ stores and inositol 1,4,5-trisphosphate mediated nuclear Ca2+ cycling in cardiomyocytes.
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