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Search results 1 to 100 out of 235 for Pltp

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Type Details Score
Gene
5360 | PLTP
Type: gene
Organism: human
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Gene
505640 | PLTP
Type: gene
Organism: cattle
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Gene
428164 | PLTP
Type: gene
Organism: chicken
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Gene
445125 | pltp
Type: gene
Organism: zebrafish
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Gene
708711 | PLTP
Type: gene
Organism: macaque, rhesus
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Gene
549505 | pltp
Type: gene
Organism: frog, western clawed
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Gene
296371 | Pltp
Type: gene
Organism: rat
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Gene
485903 | PLTP
Type: gene
Organism: dog, domestic
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Gene
458291 | PLTP
Type: gene
Organism: chimpanzee
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Protein Domain
IPR030179 | PLTP
Type: Family
Description: Phospholipid transfer protein (PLTP) is a nonspecific lipid transfer protein. Besides phospholipids, PLTP efficiently transfers diacylglycerol, alpha-tocopherol, cerebroside, and lipopolysaccharides []. These transport functions play an important role in lipid and lipoprotein metabolism. Lipoprotein-associated PLTP proteins exist in both active and inactive forms. Active plasma PLTP is associated with apoA-I- containing lipoproteins and inactive one is associated with apoE-containing lipoproteins []. PLTP is considered a promising pharmacological target to treat atherosclerosis [].
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Protein Coding Gene
MGI:103151 | Pltp
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q4FJT5
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Publication
17928634 | J:130081
First Author: Valenta DT
Year: 2008
Journal: J Lipid Res
Title: Macrophage PLTP is atheroprotective in LDLr-deficient mice with systemic PLTP deficiency.
Volume: 49
Issue: 1
Pages: 24-32
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Publication
6733137 | -
First Author: Massey JB
Year: 1984
Journal: Biochim Biophys Acta
Title: Measurement and prediction of the rates of spontaneous transfer of phospholipids between plasma lipoproteins.
Volume: 794
Issue: 2
Pages: 274-80
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Publication
16520487 | -
First Author: Cheung MC
Year: 2006
Journal: J Lipid Res
Title: Active plasma phospholipid transfer protein is associated with apoA-I- but not apoE-containing lipoproteins.
Volume: 47
Issue: 6
Pages: 1315-21
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Publication
22897926 | -
First Author: Jiang XC
Year: 2012
Journal: Nutr Metab (Lond)
Title: The impact of phospholipid transfer protein (PLTP) on lipoprotein metabolism.
Volume: 9
Issue: 1
Pages: 75
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Publication
18711210 | J:142969
First Author: Samyn H
Year: 2008
Journal: J Lipid Res
Title: Plasma phospholipid transfer activity is essential for increased atherogenesis in PLTP transgenic mice: a mutation-inactivation study.
Volume: 49
Issue: 12
Pages: 2504-12
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Publication
7654777 | J:28372
First Author: Albers JJ
Year: 1995
Journal: Biochim Biophys Acta
Title: Functional expression of human and mouse plasma phospholipid transfer protein: effect of recombinant and plasma PLTP on HDL subspecies.
Volume: 1258
Issue: 1
Pages: 27-34
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Publication
19422933 | J:153479
First Author: Samyn H
Year: 2009
Journal: Biochim Biophys Acta
Title: Reduction of HDL levels lowers plasma PLTP and affects its distribution among lipoproteins in mice.
Volume: 1791
Issue: 8
Pages: 790-6
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Publication
15258196 | J:93620
First Author: Yan D
Year: 2004
Journal: J Lipid Res
Title: PLTP deficiency improves the anti-inflammatory properties of HDL and reduces the ability of LDL to induce monocyte chemotactic activity.
Volume: 45
Issue: 10
Pages: 1852-8
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Publication
10356658 | J:55292
First Author: Tu AY
Year: 1999
Journal: Int J Clin Lab Res
Title: Introduction of the human PLTP transgene suppresses the atherogenic diet-induced increase in plasma phospholipid transfer activity in C57BL/6 mice.
Volume: 29
Issue: 1
Pages: 14-21
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Protein
A2A5K3
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: true
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Protein
A2A5K4
Organism: Mus musculus/domesticus
Length: 165  
Fragment?: true
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Protein
Q3UE59
Organism: Mus musculus/domesticus
Length: 377  
Fragment?: true
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Protein
P55065
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Protein
A2A5K2
Organism: Mus musculus/domesticus
Length: 441  
Fragment?: false
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Protein
Q3UFS5
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Publication
14592843 | J:86340
First Author: Korstanje R
Year: 2004
Journal: Arterioscler Thromb Vasc Biol
Title: Quantitative trait locus mapping of genes that regulate phospholipid transfer activity in SM/J and NZB/BlNJ inbred mice.
Volume: 24
Issue: 1
Pages: 155-60
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Publication
9099868 | J:39306
First Author: Tu AY
Year: 1997
Journal: Gene
Title: Characterization of the mouse gene encoding phospholipid transfer protein.
Volume: 188
Issue: 1
Pages: 115-8
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Publication
15863365 | J:99061
First Author: Schlitt A
Year: 2005
Journal: Biochim Biophys Acta
Title: Anti-inflammatory effects of phospholipid transfer protein (PLTP) deficiency in mice.
Volume: 1733
Issue: 2-3
Pages: 187-91
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Publication
17717294 | J:134876
First Author: Ogier N
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Cholesterol accumulation is increased in macrophages of phospholipid transfer protein-deficient mice: normalization by dietary alpha-tocopherol supplementation.
Volume: 27
Issue: 11
Pages: 2407-12
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Publication
18198166 | J:133585
First Author: Shelly L
Year: 2008
Journal: J Lipid Res
Title: Phospholipid transfer protein deficiency ameliorates diet-induced hypercholesterolemia and inflammation in mice.
Volume: 49
Issue: 4
Pages: 773-81
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Publication
25324570 | J:230460
First Author: Zhang K
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Phospholipid transfer protein destabilizes mouse atherosclerotic plaque.
Volume: 34
Issue: 12
Pages: 2537-44
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Publication
10079112 | J:53521
First Author: Jiang XC
Year: 1999
Journal: J Clin Invest
Title: Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels.
Volume: 103
Issue: 6
Pages: 907-14
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Publication
11083872 | J:67597
First Author: Desrumaux C
Year: 2001
Journal: J Biol Chem
Title: A hydrophobic cluster at the surface of the human plasma phospholipid transfer protein is critical for activity on high density lipoproteins.
Volume: 276
Issue: 8
Pages: 5908-15
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Publication
22367708 | J:318775
First Author: Yazdanyar A
Year: 2012
Journal: Hepatology
Title: Liver phospholipid transfer protein (PLTP) expression with a PLTP-null background promotes very low-density lipoprotein production in mice.
Volume: 56
Issue: 2
Pages: 576-84
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Publication
25477345 | J:232608
First Author: Jiang H
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Adipocyte phospholipid transfer protein and lipoprotein metabolism.
Volume: 35
Issue: 2
Pages: 316-22
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Publication
31220615 | J:279668
First Author: Song G
Year: 2019
Journal: Biochim Biophys Acta Mol Cell Biol Lipids
Title: Phospholipid transfer protein (PLTP) deficiency attenuates high fat diet induced obesity and insulin resistance.
Volume: 1864
Issue: 10
Pages: 1305-1313
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Publication
30618663 | J:275350
 
First Author: Desrumaux CM
Year: 2018
Journal: Front Behav Neurosci
Title: Brain Vitamin E Deficiency During Development Is Associated With Increased Glutamate Levels and Anxiety in Adult Mice.
Volume: 12
Pages: 310
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Publication
17641249 | J:134894
First Author: Liu R
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Phospholipid transfer protein-deficient mice absorb less cholesterol.
Volume: 27
Issue: 9
Pages: 2014-21
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Publication
16467369 | J:107906
First Author: Drouineaud V
Year: 2006
Journal: FASEB J
Title: Phospholipid transfer protein deficiency reduces sperm motility and impairs fertility of mouse males.
Volume: 20
Issue: 6
Pages: 794-6
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Publication
15734742 | J:99065
First Author: Jiang XC
Year: 2005
Journal: J Biol Chem
Title: Phospholipid transfer protein deficiency impairs apolipoprotein-B secretion from hepatocytes by stimulating a proteolytic pathway through a relative deficiency of vitamin E and an increase in intracellular oxidants.
Volume: 280
Issue: 18
Pages: 18336-40
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Publication
34054798 | J:311685
 
First Author: Nguyen M
Year: 2021
Journal: Front Immunol
Title: Intra-Abdominal Lipopolysaccharide Clearance and Inactivation in Peritonitis: Key Roles for Lipoproteins and the Phospholipid Transfer Protein.
Volume: 12
Pages: 622935
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Publication
25638820 | J:220558
First Author: Manchekar M
Year: 2015
Journal: J Biol Chem
Title: Phospholipid transfer protein plays a major role in the initiation of apolipoprotein B-containing lipoprotein assembly in mouse primary hepatocytes.
Volume: 290
Issue: 13
Pages: 8196-205
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Publication
16687660 | J:112586
First Author: Lee-Rueckert M
Year: 2006
Journal: J Lipid Res
Title: Absence of endogenous phospholipid transfer protein impairs ABCA1-dependent efflux of cholesterol from macrophage foam cells.
Volume: 47
Issue: 8
Pages: 1725-32
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Publication
28137768 | J:240456
First Author: Kuwano T
Year: 2017
Journal: J Lipid Res
Title: Overexpression and deletion of phospholipid transfer protein reduce HDL mass and cholesterol efflux capacity but not macrophage reverse cholesterol transport.
Volume: 58
Issue: 4
Pages: 731-741
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Publication
30337619 | J:268573
First Author: Ochieng P
Year: 2018
Journal: Sci Rep
Title: Phospholipid transfer protein and alpha-1 antitrypsin regulate Hck kinase activity during neutrophil degranulation.
Volume: 8
Issue: 1
Pages: 15394
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Publication
15576481 | J:105096
First Author: Desrumaux C
Year: 2005
Journal: FASEB J
Title: Phospholipid transfer protein (PLTP) deficiency reduces brain vitamin E content and increases anxiety in mice.
Volume: 19
Issue: 2
Pages: 296-7
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Publication
21514421 | J:171592
First Author: Setälä NL
Year: 2011
Journal: Am J Pathol
Title: Dry eye symptoms are increased in mice deficient in phospholipid transfer protein (PLTP).
Volume: 178
Issue: 5
Pages: 2058-65
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Publication
10893412 | J:64848
First Author: Kawano K
Year: 2000
Journal: J Biol Chem
Title: Cholesteryl ester transfer protein and phospholipid transfer protein have nonoverlapping functions in vivo.
Volume: 275
Issue: 38
Pages: 29477-81
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Publication
18458077 | J:138121
First Author: Gautier T
Year: 2008
Journal: J Biol Chem
Title: Effect of plasma phospholipid transfer protein deficiency on lethal endotoxemia in mice.
Volume: 283
Issue: 27
Pages: 18702-10
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Publication
20864671 | J:183145
First Author: Desrumaux C
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: Plasma phospholipid transfer protein deficiency in mice is associated with a reduced thrombotic response to acute intravascular oxidative stress.
Volume: 30
Issue: 12
Pages: 2452-7
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Publication
11573953 | J:72200
First Author: Tu AY
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Functional analysis of the transcriptional activity of the mouse phospholipid transfer protein gene.
Volume: 287
Issue: 4
Pages: 921-6
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Publication
11716766 | J:73340
First Author: Lie J
Year: 2001
Journal: Biochem J
Title: Evaluation of phospholipid transfer protein and cholesteryl ester transfer protein as contributors to the generation of pre beta-high-density lipoproteins.
Volume: 360
Issue: Pt 2
Pages: 379-85
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Publication
15832314 | J:100444
First Author: Lee KF
Year: 2005
Journal: J Cell Biochem
Title: Phospholipid transfer protein (PLTP) mRNA expression is stimulated by developing embryos in the oviduct.
Volume: 95
Issue: 4
Pages: 740-9
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Publication
25060793 | J:227172
First Author: Ji A
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Impact of phospholipid transfer protein on nascent high-density lipoprotein formation and remodeling.
Volume: 34
Issue: 9
Pages: 1910-6
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Publication
33798923 | J:322335
 
First Author: Zhang K
Year: 2021
Journal: Atherosclerosis
Title: Inducible phospholipid transfer protein deficiency ameliorates atherosclerosis.
Volume: 324
Pages: 9-17
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Publication
26160914 | J:318357
First Author: Tong Y
Year: 2015
Journal: Hum Mol Genet
Title: Phospholipid transfer protein (PLTP) deficiency accelerates memory dysfunction through altering amyloid precursor protein (APP) processing in a mouse model of Alzheimer's disease.
Volume: 24
Issue: 19
Pages: 5388-403
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Publication
10681411 | J:60580
First Author: Qin S
Year: 2000
Journal: J Lipid Res
Title: Phospholipid transfer protein gene knock-out mice have low high density lipoprotein levels, due to hypercatabolism, and accumulate apoA-IV-rich lamellar lipoproteins.
Volume: 41
Issue: 2
Pages: 269-76
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Publication
20543142 | J:165459
First Author: Yeang C
Year: 2010
Journal: J Lipid Res
Title: Diet-induced lipid accumulation in phospholipid transfer protein-deficient mice: its atherogenicity and potential mechanism.
Volume: 51
Issue: 10
Pages: 2993-3002
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Publication
11433351 | J:70250
First Author: Jiang XC
Year: 2001
Journal: Nat Med
Title: Apolipoprotein B secretion and atherosclerosis are decreased in mice with phospholipid-transfer protein deficiency.
Volume: 7
Issue: 7
Pages: 847-52
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Publication
23846500 | J:239143
First Author: Yazdanyar A
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Liver-specific phospholipid transfer protein deficiency reduces high-density lipoprotein and non-high-density lipoprotein production in mice.
Volume: 33
Issue: 9
Pages: 2058-64
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Publication
29731975 | J:298183
First Author: Mansuy M
Year: 2018
Journal: Oncotarget
Title: Deletion of plasma Phospholipid Transfer Protein (PLTP) increases microglial phagocytosis and reduces cerebral amyloid-β deposition in the J20 mouse model of Alzheimer's disease.
Volume: 9
Issue: 28
Pages: 19688-19703
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Publication
19524061 | J:153460
First Author: van Haperen R
Year: 2009
Journal: Biochim Biophys Acta
Title: Novel roles of hepatic lipase and phospholipid transfer protein in VLDL as well as HDL metabolism.
Volume: 1791
Issue: 10
Pages: 1031-6
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Publication
31941380 | J:304885
First Author: Hoekstra M
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: Disruption of Phospholipid Transfer Protein-Mediated High-Density Lipoprotein Maturation Reduces Scavenger Receptor BI Deficiency-Driven Atherosclerosis Susceptibility Despite Unexpected Metabolic Complications.
Volume: 40
Issue: 3
Pages: 611-623
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Publication
17170377 | J:148673
First Author: Vikstedt R
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Macrophage phospholipid transfer protein contributes significantly to total plasma phospholipid transfer activity and its deficiency leads to diminished atherosclerotic lesion development.
Volume: 27
Issue: 3
Pages: 578-86
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Publication
23830874 | J:200607
First Author: Deckert V
Year: 2013
Journal: Am J Pathol
Title: Development of abdominal aortic aneurysm is decreased in mice with plasma phospholipid transfer protein deficiency.
Volume: 183
Issue: 3
Pages: 975-86
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Publication
12105225 | J:120468
First Author: Jiang XC
Year: 2002
Journal: J Biol Chem
Title: Phospholipid transfer protein deficiency protects circulating lipoproteins from oxidation due to the enhanced accumulation of vitamin E.
Volume: 277
Issue: 35
Pages: 31850-6
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Publication
30875130 | J:278283
First Author: Rostampour N
Year: 2019
Journal: Dev Dyn
Title: Expression of new genes in vertebrate tooth development and p63 signaling.
Volume: 248
Issue: 8
Pages: 744-755
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Protein Coding Gene
MGP_CAROLIEiJ_G0024674 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026880 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026847 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026818 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026856 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026598 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_103151 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027303 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0026056 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026575 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026713 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026679 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026698 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027360 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025793 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0026129 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0026116 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025594 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
7615508 | J:27216
First Author: Jiang XC
Year: 1995
Journal: J Biol Chem
Title: Regulation of murine plasma phospholipid transfer protein activity and mRNA levels by lipopolysaccharide and high cholesterol diet.
Volume: 270
Issue: 29
Pages: 17133-8
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Publication
28765208 | J:250551
First Author: Perrier V
Year: 2017
Journal: J Lipid Res
Title: Plasma cholesterol level determines in vivo prion propagation.
Volume: 58
Issue: 10
Pages: 1950-1961
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Publication
33500240 | J:312435
 
First Author: Dusuel A
Year: 2020
Journal: J Lipid Res
Title: Human cholesteryl ester transfer protein lacks lipopolysaccharide transfer activity, but worsens inflammation and sepsis outcomes in mice.
Volume: 62
Pages: 100011
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Publication
16825594 | J:127991
First Author: Klein A
Year: 2006
Journal: Arterioscler Thromb Vasc Biol
Title: Alpha-tocopherol modulates phosphatidylserine externalization in erythrocytes: relevance in phospholipid transfer protein-deficient mice.
Volume: 26
Issue: 9
Pages: 2160-7
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Publication
26023073 | J:224394
First Author: Pais de Barros JP
Year: 2015
Journal: J Lipid Res
Title: Quantitative lipopolysaccharide analysis using HPLC/MS/MS and its combination with the limulus amebocyte lysate assay.
Volume: 56
Issue: 7
Pages: 1363-9
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GXD Expression
GXD Expression
     
Probe: MGI:3693772
Assay Type: RT-PCR
Annotation Date: 2007-01-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1771322
Stage: TS22
Assay Id: MGI:3693771
Age: embryonic day 14.5
Specimen Label: wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
       
Probe: MGI:3693772
Assay Type: RT-PCR
Annotation Date: 2007-01-15
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1771322
Stage: TS22
Assay Id: MGI:3693771
Age: embryonic day 14.5
Specimen Label: Runx2-/-
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7517000
Assay Type: Northern blot
Annotation Date: 2023-08-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7517012
Age: postnatal adult
Specimen Label: B
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7517000
Assay Type: Northern blot
Annotation Date: 2023-08-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:7517012
Age: postnatal adult
Specimen Label: K
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
       
Probe: MGI:7517000
Assay Type: Northern blot
Annotation Date: 2023-08-11
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7517012
Age: postnatal adult
Specimen Label: L
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7517000
Assay Type: Northern blot
Annotation Date: 2023-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:7517012
Age: postnatal adult
Specimen Label: Lg
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7517000
Assay Type: Northern blot
Annotation Date: 2023-08-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:7517012
Age: postnatal adult
Specimen Label: Sp
Detected: false
Specimen Num: 5
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