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Search results 1 to 100 out of 8099 for Pml

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
5371 | PML
Type: gene
Organism: human
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Gene
487641 | PML
Type: gene
Organism: dog, domestic
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Gene
100138545 | PML
Type: gene
Organism: cattle
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Gene
415302 | PML
Type: gene
Organism: chicken
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Gene
700379 | PML
Type: gene
Organism: macaque, rhesus
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Gene
315713 | Pml
Type: gene
Organism: rat
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Gene
453736 | PML
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:104662 | Pml
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
21779477 | J:244192
First Author: Lunardi A
Year: 2011
Journal: Genes Cancer
Title: A Role for PML in Innate Immunity.
Volume: 2
Issue: 1
Pages: 10-9
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Publication
9806545 | J:50588
First Author: Wang ZG
Year: 1998
Journal: Nat Genet
Title: PML is essential for multiple apoptotic pathways.
Volume: 20
Issue: 3
Pages: 266-72
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Publication
10779416 | J:123220
First Author: Zhong S
Year: 2000
Journal: Blood
Title: Role of SUMO-1-modified PML in nuclear body formation.
Volume: 95
Issue: 9
Pages: 2748-52
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Publication
8563172 | J:29383
First Author: Goddard AD
Year: 1995
Journal: Mamm Genome
Title: Cloning of the murine homolog of the leukemia-associated PML gene.
Volume: 6
Issue: 10
Pages: 732-7
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Publication
9488655 | J:46381
First Author: Wang ZG
Year: 1998
Journal: Science
Title: Role of PML in cell growth and the retinoic acid pathway.
Volume: 279
Issue: 5356
Pages: 1547-51
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Publication
15356634 | J:92664
First Author: Lin HK
Year: 2004
Journal: Nature
Title: Cytoplasmic PML function in TGF-beta signalling.
Volume: 431
Issue: 7005
Pages: 205-11
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Publication
19136970 | J:146180
First Author: Regad T
Year: 2009
Journal: Nat Neurosci
Title: The tumor suppressor Pml regulates cell fate in the developing neocortex.
Volume: 12
Issue: 2
Pages: 132-40
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Publication
21427174 | J:172072
First Author: Khalfin-Rabinovich Y
Year: 2011
Journal: Int Immunol
Title: PML is a key component for the differentiation of myeloid progenitor cells to macrophages.
Volume: 23
Issue: 4
Pages: 287-96
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Publication
22274616 | J:181918
First Author: Miki T
Year: 2012
Journal: EMBO J
Title: PML regulates PER2 nuclear localization and circadian function.
Volume: 31
Issue: 6
Pages: 1427-39
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Publication
21030605 | J:166717
First Author: Giorgi C
Year: 2010
Journal: Science
Title: PML regulates apoptosis at endoplasmic reticulum by modulating calcium release.
Volume: 330
Issue: 6008
Pages: 1247-51
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Publication
16915281 | J:111744
First Author: Bernardi R
Year: 2006
Journal: Nature
Title: PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR.
Volume: 442
Issue: 7104
Pages: 779-85
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Publication
15195100 | J:169789
First Author: Bernardi R
Year: 2004
Journal: Nat Cell Biol
Title: PML regulates p53 stability by sequestering Mdm2 to the nucleolus.
Volume: 6
Issue: 7
Pages: 665-72
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Publication
22886304 | J:191430
First Author: Carracedo A
Year: 2012
Journal: J Clin Invest
Title: A metabolic prosurvival role for PML in breast cancer.
Volume: 122
Issue: 9
Pages: 3088-100
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Publication
11025664 | J:119165
First Author: Guo A
Year: 2000
Journal: Nat Cell Biol
Title: The function of PML in p53-dependent apoptosis.
Volume: 2
Issue: 10
Pages: 730-6
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Publication
18469801 | J:137294
First Author: Ito K
Year: 2008
Journal: Nature
Title: PML targeting eradicates quiescent leukaemia-initiating cells.
Volume: 453
Issue: 7198
Pages: 1072-8
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Publication
16873060 | J:144680
First Author: Scaglioni PP
Year: 2006
Journal: Cell
Title: A CK2-dependent mechanism for degradation of the PML tumor suppressor.
Volume: 126
Issue: 2
Pages: 269-83
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Publication
23279884 | J:206771
First Author: Butler K
Year: 2013
Journal: Genes Brain Behav
Title: Impaired cognitive function and reduced anxiety-related behavior in a promyelocytic leukemia (PML) tumor suppressor protein-deficient mouse.
Volume: 12
Issue: 2
Pages: 189-202
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Publication
21387562 | J:234610
First Author: Bernardi R
Year: 2011
Journal: EMBO Mol Med
Title: Pml represses tumour progression through inhibition of mTOR.
Volume: 3
Issue: 5
Pages: 249-57
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Publication
19325566 | J:164182
First Author: Louria-Hayon I
Year: 2009
Journal: Cell Death Differ
Title: E6AP promotes the degradation of the PML tumor suppressor.
Volume: 16
Issue: 8
Pages: 1156-66
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Publication
28931625 | J:251560
First Author: Niwa-Kawakita M
Year: 2017
Journal: J Exp Med
Title: PML is a ROS sensor activating p53 upon oxidative stress.
Volume: 214
Issue: 11
Pages: 3197-3206
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Publication
22685230 | J:205030
First Author: Okino Y
Year: 2012
Journal: J Biochem
Title: Moloney murine leukemia virus integrase and reverse transcriptase interact with PML proteins.
Volume: 152
Issue: 2
Pages: 161-9
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Publication
26578773 | J:228053
First Author: Ivanschitz L
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: PML IV/ARF interaction enhances p53 SUMO-1 conjugation, activation, and senescence.
Volume: 112
Issue: 46
Pages: 14278-83
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Publication
14992722 | J:88573
First Author: de Stanchina E
Year: 2004
Journal: Mol Cell
Title: PML is a direct p53 target that modulates p53 effector functions.
Volume: 13
Issue: 4
Pages: 523-35
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Publication
10910364 | J:123219
First Author: Pearson M
Year: 2000
Journal: Nature
Title: PML regulates p53 acetylation and premature senescence induced by oncogenic Ras.
Volume: 406
Issue: 6792
Pages: 207-10
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Publication
29302031 | J:256973
First Author: Guarnerio J
Year: 2018
Journal: Nat Commun
Title: A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche.
Volume: 9
Issue: 1
Pages: 66
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GXD Expression
GXD Expression
     
Probe: MGI:6180885
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191106
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pml
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6180885
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191106
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pml
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6180885
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191106
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pml
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6180885
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191106
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pml
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6180885
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191106
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pml
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6180885
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191106
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pml
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6180885
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191106
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pml
Detected: true
Specimen Num: 7
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Publication
17878236 | J:128349
First Author: Condemine W
Year: 2007
Journal: J Cell Sci
Title: A nucleolar targeting signal in PML-I addresses PML to nucleolar caps in stressed or senescent cells.
Volume: 120
Issue: Pt 18
Pages: 3219-27
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Publication
15626733 | J:98981
First Author: Salomoni P
Year: 2005
Journal: Blood
Title: The promyelocytic leukemia protein PML regulates c-Jun function in response to DNA damage.
Volume: 105
Issue: 9
Pages: 3686-90
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Publication
9845074 | J:51294
First Author: Zheng P
Year: 1998
Journal: Nature
Title: Proto-oncogene PML controls genes devoted to MHC class I antigen presentation.
Volume: 396
Issue: 6709
Pages: 373-6
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Publication
27545895 | J:239031
First Author: Missiroli S
Year: 2016
Journal: Cell Rep
Title: PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development.
Volume: 16
Issue: 9
Pages: 2415-27
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Publication
16818720 | J:111110
First Author: Janer A
Year: 2006
Journal: J Cell Biol
Title: PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins.
Volume: 174
Issue: 1
Pages: 65-76
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Publication
22002537 | J:180063
First Author: Martin N
Year: 2012
Journal: EMBO J
Title: Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence.
Volume: 31
Issue: 1
Pages: 95-109
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Publication
24943846 | J:317641
First Author: Guo S
Year: 2014
Journal: Mol Biol Cell
Title: Control of antioxidative response by the tumor suppressor protein PML through regulating Nrf2 activity.
Volume: 25
Issue: 16
Pages: 2485-98
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Publication
24637324 | J:215811
First Author: Sahin U
Year: 2014
Journal: J Cell Biol
Title: Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins.
Volume: 204
Issue: 6
Pages: 931-45
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Publication
17562868 | J:125015
First Author: Yoshida H
Year: 2007
Journal: Mol Cell Biol
Title: PML-retinoic acid receptor alpha inhibits PML IV enhancement of PU.1-induced C/EBPepsilon expression in myeloid differentiation.
Volume: 27
Issue: 16
Pages: 5819-34
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Publication
29191918 | J:262172
First Author: Voisset E
Year: 2018
Journal: Blood
Title: Pml nuclear body disruption cooperates in APL pathogenesis and impairs DNA damage repair pathways in mice.
Volume: 131
Issue: 6
Pages: 636-648
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Publication
11500381 | J:118799
First Author: Cohen N
Year: 2001
Journal: EMBO J
Title: PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.
Volume: 20
Issue: 16
Pages: 4547-59
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Publication
23656786 | J:317504
First Author: Haupt S
Year: 2013
Journal: Cell Cycle
Title: Loss of PML cooperates with mutant p53 to drive more aggressive cancers in a gender-dependent manner.
Volume: 12
Issue: 11
Pages: 1722-31
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Publication
15735755 | J:97160
First Author: Cairo S
Year: 2005
Journal: Oncogene
Title: PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts.
Volume: 24
Issue: 13
Pages: 2195-203
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Publication
35229101 | J:325618
 
First Author: Wani S
Year: 2022
Journal: Dis Model Mech
Title: The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption.
Volume: 15
Issue: 4
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Publication
28432122 | J:245633
First Author: Hsu KS
Year: 2017
Journal: J Biol Chem
Title: Dual regulation of Stat1 and Stat3 by the tumor suppressor protein PML contributes to interferon α-mediated inhibition of angiogenesis.
Volume: 292
Issue: 24
Pages: 10048-10060
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Publication
24615016 | J:213662
First Author: Münch S
Year: 2014
Journal: Mol Cell Biol
Title: The tumor suppressor PML specifically accumulates at RPA/Rad51-containing DNA damage repair foci but is nonessential for DNA damage-induced fibroblast senescence.
Volume: 34
Issue: 10
Pages: 1733-46
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Publication
17187077 | J:245382
First Author: Park SW
Year: 2007
Journal: Nat Struct Mol Biol
Title: SUMOylation of Tr2 orphan receptor involves Pml and fine-tunes Oct4 expression in stem cells.
Volume: 14
Issue: 1
Pages: 68-75
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Publication
19261859 | J:147092
First Author: Li W
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: PML depletion disrupts normal mammary gland development and skews the composition of the mammary luminal cell progenitor pool.
Volume: 106
Issue: 12
Pages: 4725-30
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GO Term
GO:0016605 | PML body
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Publication
18682553 | J:175152
First Author: Gupta P
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression.
Volume: 105
Issue: 32
Pages: 11424-9
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Publication
19033381 | J:141678
First Author: Evdokimov E
Year: 2008
Journal: J Cell Sci
Title: Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3.
Volume: 121
Issue: Pt 24
Pages: 4106-13
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GO Term
GO:0030578 | PML body organization
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UniProt Feature
UniProt Feature
Begin: 1
Description: Protein PML
Type: chain
End: 885
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Publication
11087871 | J:65883
First Author: Zimonjic DB
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Acquired, nonrandom chromosomal abnormalities associated with the development of acute promyelocytic leukemia in transgenic mice.
Volume: 97
Issue: 24
Pages: 13306-11
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Publication
11181703 | J:67484
First Author: Rego EM
Year: 2001
Journal: J Exp Med
Title: Role of promyelocytic leukemia (PML) protein in tumor suppression.
Volume: 193
Issue: 4
Pages: 521-29
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Publication
26595813 | J:229822
First Author: Cole CB
Year: 2016
Journal: J Clin Invest
Title: PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia.
Volume: 126
Issue: 1
Pages: 85-98
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Publication
28486108 | J:242575
First Author: Li K
Year: 2017
Journal: Cancer Cell
Title: TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence.
Volume: 31
Issue: 5
Pages: 697-710.e7
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Publication
9144232 | J:40373
First Author: He LZ
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice.
Volume: 94
Issue: 10
Pages: 5302-7
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Publication
10611345 | J:59080
First Author: Pollock JL
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: A bcr-3 isoform of RARalpha-PML potentiates the development of PML-RARalpha-driven acute promyelocytic leukemia.
Volume: 96
Issue: 26
Pages: 15103-8
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MP Term
MP:0008886 | abnormal PML bodies
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Publication
19745809 | J:154718
First Author: Pan D
Year: 2009
Journal: EMBO J
Title: SnoN functions as a tumour suppressor by inducing premature senescence.
Volume: 28
Issue: 22
Pages: 3500-13
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Publication
21364283 | J:172024
First Author: Welch JS
Year: 2011
Journal: J Clin Invest
Title: PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice.
Volume: 121
Issue: 4
Pages: 1636-45
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Publication
24337744 | J:207325
First Author: Maier NK
Year: 2014
Journal: J Immunol
Title: Arsenic trioxide and other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes.
Volume: 192
Issue: 2
Pages: 763-70
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Publication
23986437 | J:204555
First Author: Cheng X
Year: 2013
Journal: J Biol Chem
Title: Ablation of promyelocytic leukemia protein (PML) re-patterns energy balance and protects mice from obesity induced by a Western diet.
Volume: 288
Issue: 41
Pages: 29746-59
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Publication
28074065 | J:241030
First Author: Mehdipour P
Year: 2017
Journal: Leukemia
Title: HDAC3 activity is required for initiation of leukemogenesis in acute promyelocytic leukemia.
Volume: 31
Issue: 4
Pages: 995-997
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GO Term
GO:0075341 | host cell PML body
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Publication
24407287 | J:219619
First Author: Dowling JK
Year: 2014
Journal: J Biol Chem
Title: Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.
Volume: 289
Issue: 10
Pages: 6429-37
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Publication
20609355 | J:161779
First Author: Jeanne M
Year: 2010
Journal: Cancer Cell
Title: PML/RARA oxidation and arsenic binding initiate the antileukemia response of As2O3.
Volume: 18
Issue: 1
Pages: 88-98
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Publication
28700942 | J:254517
First Author: Amodeo V
Year: 2017
Journal: Cell Rep
Title: A PML/Slit Axis Controls Physiological Cell Migration and Cancer Invasion in the CNS.
Volume: 20
Issue: 2
Pages: 411-426
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Publication
10684855 | J:169813
First Author: Zhong S
Year: 2000
Journal: J Exp Med
Title: Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis.
Volume: 191
Issue: 4
Pages: 631-40
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Publication
16461359 | J:105718
First Author: Qin Q
Year: 2006
Journal: J Cell Biol
Title: A novel GTPase, CRAG, mediates promyelocytic leukemia protein-associated nuclear body formation and degradation of expanded polyglutamine protein.
Volume: 172
Issue: 4
Pages: 497-504
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Publication
24882209 | J:215335
First Author: Guo L
Year: 2014
Journal: Mol Cell
Title: A cellular system that degrades misfolded proteins and protects against neurodegeneration.
Volume: 55
Issue: 1
Pages: 15-30
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Publication
17081986 | J:240279
First Author: Lin DY
Year: 2006
Journal: Mol Cell
Title: Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors.
Volume: 24
Issue: 3
Pages: 341-54
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Publication
22902876 | J:192771
First Author: Ito K
Year: 2012
Journal: Nat Med
Title: A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance.
Volume: 18
Issue: 9
Pages: 1350-8
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Publication
28777872 | J:266112
First Author: Li Y
Year: 2017
Journal: FEBS Lett
Title: The short isoform of PML-RARα activates the NRF2/HO-1 pathway through a direct interaction with NRF2.
Volume: 591
Issue: 18
Pages: 2859-2868
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Publication
23430110 | J:196693
First Author: Lo YH
Year: 2013
Journal: Blood
Title: Selective inhibition of the NLRP3 inflammasome by targeting to promyelocytic leukemia protein in mouse and human.
Volume: 121
Issue: 16
Pages: 3185-94
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Publication
17121994 | J:118287
First Author: Choi YH
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: The promyelocytic leukemia protein functions as a negative regulator of IFN-gamma signaling.
Volume: 103
Issue: 49
Pages: 18715-20
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Publication
33075130 | J:307781
 
First Author: Dagher T
Year: 2021
Journal: J Exp Med
Title: JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML.
Volume: 218
Issue: 2
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Publication
19390558 | J:164178
First Author: Laane E
Year: 2009
Journal: Cell Death Differ
Title: Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy.
Volume: 16
Issue: 7
Pages: 1018-29
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Publication
21846906 | J:182171
First Author: Kim MK
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Promyelocytic leukemia inhibits adipogenesis, and loss of promyelocytic leukemia results in fat accumulation in mice.
Volume: 301
Issue: 6
Pages: E1130-42
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Publication
23620081 | J:198825
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