Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The epithelial membrane proteins (EMP-1, -2 and -3), peripheral myelin protein 22 (PMP22), and lens fibre membrane intrinsic protein (LMIP) comprise a protein family on the basis of sequence and structural similarities []. Each family member is a small hydrophobic membrane glycoprotein, ~160-170 amino acids in length, and shares a common predicted transmembrane (TM) topology of 4 TM domains, with intracellular N- and C-termini [].PMP22, also termed growth-arrest specific protein (GAS3), is a structural component of compact myelin in the peripheral nervous system. Aberrant expression of the PMP22 gene, and mutations in the protein, are associated with a variety of hereditary peripheral motor and sensory neuropathies []. An intra-chromosomal duplication containing the PMP22 gene is found in the majority of patients suffering from the autosomal dominant demyelinating neuropathy Charcot-Marie-Tooth disease 1A (CMT1A) []. In addition, rare point mutations in PMP22 have been found in non-duplication CMT1A patients and in the severe congenital peripheral neuropathy Dejerine-Sottas syndrome [].PMP22 is also implicated in the control of cell proliferation. Its expression levels are up-regulated in cells undergoing growth arrest [], and it has been shown that modulating PMP22 levels in cultured Schwann cells exerts a profound effect on the length of the G1 phase of the cell cycle []. It has also been demonstrated that over-expression of PMP22 in NIH 3T3 fibroblast cells induces apoptosis []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Roa BB |
Year: |
1993 |
Journal: |
Nat Genet |
Title: |
Dejerine-Sottas syndrome associated with point mutation in the peripheral myelin protein 22 (PMP22) gene. |
Volume: |
5 |
Issue: |
3 |
Pages: |
269-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lobsiger CS |
Year: |
1996 |
Journal: |
Genomics |
Title: |
Identification and characterization of a cDNA and the structural gene encoding the mouse epithelial membrane protein-1. |
Volume: |
36 |
Issue: |
3 |
Pages: |
379-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Taylor V |
Year: |
1995 |
Journal: |
J Biol Chem |
Title: |
Epithelial membrane protein-1, peripheral myelin protein 22, and lens membrane protein 20 define a novel gene family. |
Volume: |
270 |
Issue: |
48 |
Pages: |
28824-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zoidl G |
Year: |
1995 |
Journal: |
EMBO J |
Title: |
Retroviral-mediated gene transfer of the peripheral myelin protein PMP22 in Schwann cells: modulation of cell growth. |
Volume: |
14 |
Issue: |
6 |
Pages: |
1122-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suter U |
Year: |
1993 |
Journal: |
Trends Neurosci |
Title: |
Progress in the molecular understanding of hereditary peripheral neuropathies reveals new insights into the biology of the peripheral nervous system. |
Volume: |
16 |
Issue: |
2 |
Pages: |
50-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suter U |
Year: |
1995 |
Journal: |
Annu Rev Neurosci |
Title: |
Biology and genetics of hereditary motor and sensory neuropathies. |
Volume: |
18 |
|
Pages: |
45-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fabbretti E |
Year: |
1995 |
Journal: |
Genes Dev |
Title: |
Apoptotic phenotype induced by overexpression of wild-type gas3/PMP22: its relation to the demyelinating peripheral neuropathy CMT1A. |
Volume: |
9 |
Issue: |
15 |
Pages: |
1846-56 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
161
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
160
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Bai Y |
Year: |
2010 |
Journal: |
J Neurosci |
Title: |
Conduction block in PMP22 deficiency. |
Volume: |
30 |
Issue: |
2 |
Pages: |
600-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Magyar JP |
Year: |
1996 |
Journal: |
J Neurosci |
Title: |
Impaired differentiation of Schwann cells in transgenic mice with increased PMP22 gene dosage. |
Volume: |
16 |
Issue: |
17 |
Pages: |
5351-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Krauter D |
Year: |
2024 |
Journal: |
EMBO Mol Med |
Title: |
Targeting PI3K/Akt/mTOR signaling in rodent models of PMP22 gene-dosage diseases. |
Volume: |
16 |
Issue: |
3 |
Pages: |
616-640 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saporta MA |
Year: |
2011 |
Journal: |
Arch Neurol |
Title: |
Neuropathy in a human without the PMP22 gene. |
Volume: |
68 |
Issue: |
6 |
Pages: |
814-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jones EA |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
Regulation of the PMP22 gene through an intronic enhancer. |
Volume: |
31 |
Issue: |
11 |
Pages: |
4242-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Isaacs AM |
Year: |
2000 |
Journal: |
Hum Mol Genet |
Title: |
Identification of two new Pmp22 mouse mutants using large-scale mutagenesis and a novel rapid mapping strategy. |
Volume: |
9 |
Issue: |
12 |
Pages: |
1865-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee JS |
Year: |
2020 |
Journal: |
Nucleic Acids Res |
Title: |
Targeted PMP22 TATA-box editing by CRISPR/Cas9 reduces demyelinating neuropathy of Charcot-Marie-Tooth disease type 1A in mice. |
Volume: |
48 |
Issue: |
1 |
Pages: |
130-140 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou Y |
Year: |
2019 |
Journal: |
J Neurosci |
Title: |
PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux. |
Volume: |
39 |
Issue: |
27 |
Pages: |
5404-5418 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee JS |
Year: |
2017 |
Journal: |
Neurobiol Dis |
Title: |
Pmp22 mutant allele-specific siRNA alleviates demyelinating neuropathic phenotype in vivo. |
Volume: |
100 |
|
Pages: |
99-107 |
|
•
•
•
•
•
|
Publication |
First Author: |
Isaacs AM |
Year: |
2002 |
Journal: |
Mol Cell Neurosci |
Title: |
Identification of a new Pmp22 mouse mutant and trafficking analysis of a Pmp22 allelic series suggesting that protein aggregates may be protective in Pmp22-associated peripheral neuropathy. |
Volume: |
21 |
Issue: |
1 |
Pages: |
114-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robertson AM |
Year: |
1999 |
Journal: |
J Anat |
Title: |
Development of early postnatal peripheral nerve abnormalities in Trembler-J and PMP22 transgenic mice. |
Volume: |
195 ( Pt 3) |
|
Pages: |
331-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Giambonini-Brugnoli G |
Year: |
2005 |
Journal: |
Neurobiol Dis |
Title: |
Distinct disease mechanisms in peripheral neuropathies due to altered peripheral myelin protein 22 gene dosage or a Pmp22 point mutation. |
Volume: |
18 |
Issue: |
3 |
Pages: |
656-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
van de Wetering RA |
Year: |
1999 |
Journal: |
Mamm Genome |
Title: |
Regulation and expression of the murine PMP22 gene. |
Volume: |
10 |
Issue: |
4 |
Pages: |
419-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robertson AM |
Year: |
2002 |
Journal: |
J Anat |
Title: |
Comparison of a new pmp22 transgenic mouse line with other mouse models and human patients with CMT1A. |
Volume: |
200 |
Issue: |
4 |
Pages: |
377-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carenini S |
Year: |
1999 |
Journal: |
Glia |
Title: |
Localization and functional roles of PMP22 in peripheral nerves of P0-deficient mice. |
Volume: |
28 |
Issue: |
3 |
Pages: |
256-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee S |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
PMP22 is critical for actin-mediated cellular functions and for establishing lipid rafts. |
Volume: |
34 |
Issue: |
48 |
Pages: |
16140-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Garbay B |
Year: |
1995 |
Journal: |
Neurosci Lett |
Title: |
Expression of the exon 1A-containing PMP22 transcript is altered in the trembler mouse. |
Volume: |
198 |
Issue: |
3 |
Pages: |
157-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Colby J |
Year: |
2000 |
Journal: |
Neurobiol Dis |
Title: |
PMP22 carrying the trembler or trembler-J mutation is intracellularly retained in myelinating Schwann cells. |
Volume: |
7 |
Issue: |
6 Pt B |
Pages: |
561-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pantera H |
Year: |
2020 |
Journal: |
Hum Mol Genet |
Title: |
Pmp22 super-enhancer deletion causes tomacula formation and conduction block in peripheral nerves. |
Volume: |
29 |
Issue: |
10 |
Pages: |
1689-1699 |
|
•
•
•
•
•
|
Publication |
First Author: |
Damián JP |
Year: |
2021 |
Journal: |
Biomolecules |
Title: |
Central Alteration in Peripheral Neuropathy of Trembler-J Mice: Hippocampal pmp22 Expression and Behavioral Profile in Anxiety Tests. |
Volume: |
11 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakai Y |
Year: |
1999 |
Journal: |
Neuroscience |
Title: |
Identification of break points in mutated PMP22 gene in a new Trembler (Tr-Ncnp) mouse. |
Volume: |
88 |
Issue: |
3 |
Pages: |
989-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Toyka KV |
Year: |
1997 |
Journal: |
J Neurol Neurosurg Psychiatry |
Title: |
Hereditary neuromyotonia: a mouse model associated with deficiency or increased gene dosage of the PMP22 gene. |
Volume: |
63 |
Issue: |
6 |
Pages: |
812-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dionne L |
Year: |
2013 |
Journal: |
MGI Direct Data Submission |
Title: |
Trembler 2 Jackson, a spontaneous point mutation in Pmp22 |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hall A |
Year: |
2019 |
Journal: |
Sci Adv |
Title: |
RUNX represses Pmp22 to drive neurofibromagenesis. |
Volume: |
5 |
Issue: |
4 |
Pages: |
eaau8389 |
|
•
•
•
•
•
|
Publication |
First Author: |
Perea J |
Year: |
2001 |
Journal: |
Hum Mol Genet |
Title: |
Induced myelination and demyelination in a conditional mouse model of Charcot-Marie-Tooth disease type 1A. |
Volume: |
10 |
Issue: |
10 |
Pages: |
1007-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suter U |
Year: |
1999 |
Journal: |
Ann N Y Acad Sci |
Title: |
Transgenic mouse models of CMT1A and HNPP. |
Volume: |
883 |
|
Pages: |
247-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Snipes GJ |
Year: |
1999 |
Journal: |
Ann N Y Acad Sci |
Title: |
The anatomy and cell biology of peripheral myelin protein-22. |
Volume: |
883 |
|
Pages: |
143-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cassinotti LR |
Year: |
2024 |
Journal: |
JCI Insight |
Title: |
Hidden hearing loss in a Charcot-Marie-Tooth type 1A mouse model. |
Volume: |
9 |
Issue: |
19 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Suter U |
Year: |
1995 |
Journal: |
J Neurosci Res |
Title: |
Peripheral myelin protein 22: facts and hypotheses. |
Volume: |
40 |
Issue: |
2 |
Pages: |
145-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fledrich R |
Year: |
2014 |
Journal: |
Nat Med |
Title: |
Soluble neuregulin-1 modulates disease pathogenesis in rodent models of Charcot-Marie-Tooth disease 1A. |
Volume: |
20 |
Issue: |
9 |
Pages: |
1055-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bolin LM |
Year: |
1997 |
Journal: |
J Neurosci |
Title: |
HNMP-1: a novel hematopoietic and neural membrane protein differentially regulated in neural development and injury. |
Volume: |
17 |
Issue: |
14 |
Pages: |
5493-502 |
|
•
•
•
•
•
|
Publication |
First Author: |
Naef R |
Year: |
1997 |
Journal: |
Mol Cell Neurosci |
Title: |
Aberrant protein trafficking in Trembler suggests a disease mechanism for hereditary human peripheral neuropathies. |
Volume: |
9 |
Issue: |
1 |
Pages: |
13-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fortun J |
Year: |
2007 |
Journal: |
Neurobiol Dis |
Title: |
The formation of peripheral myelin protein 22 aggregates is hindered by the enhancement of autophagy and expression of cytoplasmic chaperones. |
Volume: |
25 |
Issue: |
2 |
Pages: |
252-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adlkofer K |
Year: |
1995 |
Journal: |
Nat Genet |
Title: |
Hypermyelination and demyelinating peripheral neuropathy in Pmp22-deficient mice. |
Volume: |
11 |
Issue: |
3 |
Pages: |
274-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rautenstrauss B |
Year: |
1998 |
Journal: |
J Peripher Nerv Syst |
Title: |
Expression pattern of the peripheral myelin protein 22kDa (PMP22) in neural and non-neural tissue types of adult wildtype and Trembler mice--a comparative study. |
Volume: |
3 |
Issue: |
2 |
Pages: |
117-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sancho S |
Year: |
2001 |
Journal: |
Brain |
Title: |
Regulation of Schwann cell proliferation and apoptosis in PMP22-deficient mice and mouse models of Charcot-Marie-Tooth disease type 1A. |
Volume: |
124 |
Issue: |
Pt 11 |
Pages: |
2177-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adlkofer K |
Year: |
1997 |
Journal: |
J Neurosci Res |
Title: |
Analysis of compound heterozygous mice reveals that the Trembler mutation can behave as a gain-of-function allele. |
Volume: |
49 |
Issue: |
6 |
Pages: |
671-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khajavi M |
Year: |
2007 |
Journal: |
Am J Hum Genet |
Title: |
Oral curcumin mitigates the clinical and neuropathologic phenotype of the Trembler-J mouse: a potential therapy for inherited neuropathy. |
Volume: |
81 |
Issue: |
3 |
Pages: |
438-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vanoye CG |
Year: |
2019 |
Journal: |
J Biol Chem |
Title: |
Peripheral myelin protein 22 modulates store-operated calcium channel activity, providing insights into Charcot-Marie-Tooth disease etiology. |
Volume: |
294 |
Issue: |
32 |
Pages: |
12054-12065 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robertson AM |
Year: |
1997 |
Journal: |
J Anat |
Title: |
Abnormal Schwann cell/axon interactions in the Trembler-J mouse. |
Volume: |
190 ( Pt 3) |
|
Pages: |
423-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Notterpek L |
Year: |
1997 |
Journal: |
J Neurosci |
Title: |
Upregulation of the endosomal-lysosomal pathway in the trembler-J neuropathy. |
Volume: |
17 |
Issue: |
11 |
Pages: |
4190-200 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fortun J |
Year: |
2005 |
Journal: |
J Neurochem |
Title: |
Impaired proteasome activity and accumulation of ubiquitinated substrates in a hereditary neuropathy model. |
Volume: |
92 |
Issue: |
6 |
Pages: |
1531-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nicks J |
Year: |
2014 |
Journal: |
Neurobiol Dis |
Title: |
Rapamycin improves peripheral nerve myelination while it fails to benefit neuromuscular performance in neuropathic mice. |
Volume: |
70 |
|
Pages: |
224-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adlkofer K |
Year: |
1997 |
Journal: |
J Neurosci |
Title: |
Heterozygous peripheral myelin protein 22-deficient mice are affected by a progressive demyelinating tomaculous neuropathy. |
Volume: |
17 |
Issue: |
12 |
Pages: |
4662-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nattkämper H |
Year: |
2009 |
Journal: |
J Neurochem |
Title: |
Varying survival of motoneurons and activation of distinct molecular mechanism in response to altered peripheral myelin protein 22 gene dosage. |
Volume: |
110 |
Issue: |
3 |
Pages: |
935-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sancho S |
Year: |
1999 |
Journal: |
Brain |
Title: |
Distal axonopathy in peripheral nerves of PMP22-mutant mice. |
Volume: |
122 ( Pt 8) |
|
Pages: |
1563-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robertson A |
Year: |
2002 |
Journal: |
Gene |
Title: |
Effects of mouse strain, position of integration and tetracycline analogue on the tetracycline conditional system in transgenic mice. |
Volume: |
282 |
Issue: |
1-2 |
Pages: |
65-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tobler AR |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Differential aggregation of the Trembler and Trembler J mutants of peripheral myelin protein 22. |
Volume: |
99 |
Issue: |
1 |
Pages: |
483-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suter U |
Year: |
1994 |
Journal: |
Hum Mutat |
Title: |
Genetic basis of inherited peripheral neuropathies. |
Volume: |
3 |
Issue: |
2 |
Pages: |
95-102 |
|
•
•
•
•
•
|
Publication |
First Author: |
D'Urso D |
Year: |
1998 |
Journal: |
J Neurosci |
Title: |
Overloaded endoplasmic reticulum-Golgi compartments, a possible pathomechanism of peripheral neuropathies caused by mutations of the peripheral myelin protein PMP22. |
Volume: |
18 |
Issue: |
2 |
Pages: |
731-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tobler AR |
Year: |
1999 |
Journal: |
J Neurosci |
Title: |
Transport of Trembler-J mutant peripheral myelin protein 22 is blocked in the intermediate compartment and affects the transport of the wild-type protein by direct interaction. |
Volume: |
19 |
Issue: |
6 |
Pages: |
2027-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wulf P |
Year: |
1999 |
Journal: |
Brain Res Dev Brain Res |
Title: |
Embryonic expression of epithelial membrane protein 1 in early neurons. |
Volume: |
116 |
Issue: |
2 |
Pages: |
169-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maier M |
Year: |
2002 |
Journal: |
Mol Cell Neurosci |
Title: |
Identification of the regulatory region of the peripheral myelin protein 22 (PMP22) gene that directs temporal and spatial expression in development and regeneration of peripheral nerves. |
Volume: |
20 |
Issue: |
1 |
Pages: |
93-109 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baechner D |
Year: |
1995 |
Journal: |
J Neurosci Res |
Title: |
Widespread expression of the peripheral myelin protein-22 gene (PMP22) in neural and non-neural tissues during murine development. |
Volume: |
42 |
Issue: |
6 |
Pages: |
733-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zielasek J |
Year: |
1999 |
Journal: |
Ann N Y Acad Sci |
Title: |
Nerve conduction abnormalities and neuromyotonia in genetically engineered mouse models of human hereditary neuropathies. |
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883 |
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Pages: |
310-20 |
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Publication |
First Author: |
Di Tomaso MV |
Year: |
2022 |
Journal: |
Biomolecules |
Title: |
Colocalization Analysis of Peripheral Myelin Protein-22 and Lamin-B1 in the Schwann Cell Nuclei of Wt and TrJ Mice. |
Volume: |
12 |
Issue: |
3 |
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Publication |
First Author: |
Khazaei MR |
Year: |
2010 |
Journal: |
J Neurochem |
Title: |
Bex1 is involved in the regeneration of axons after injury. |
Volume: |
115 |
Issue: |
4 |
Pages: |
910-20 |
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Publication |
First Author: |
Poitelon Y |
Year: |
2018 |
Journal: |
J Neurochem |
Title: |
A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies. |
Volume: |
145 |
Issue: |
3 |
Pages: |
245-257 |
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Publication |
First Author: |
Fortun J |
Year: |
2003 |
Journal: |
J Neurosci |
Title: |
Emerging role for autophagy in the removal of aggresomes in Schwann cells. |
Volume: |
23 |
Issue: |
33 |
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10672-80 |
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Martini R |
Year: |
1997 |
Journal: |
J Anat |
Title: |
Animal models for inherited peripheral neuropathies. |
Volume: |
191 ( Pt 3) |
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Pages: |
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Publication |
First Author: |
Atanasoski S |
Year: |
2004 |
Journal: |
Neuron |
Title: |
The protooncogene Ski controls Schwann cell proliferation and myelination. |
Volume: |
43 |
Issue: |
4 |
Pages: |
499-511 |
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Publication |
First Author: |
Amici SA |
Year: |
2006 |
Journal: |
J Neurosci |
Title: |
Peripheral myelin protein 22 is in complex with alpha6beta4 integrin, and its absence alters the Schwann cell basal lamina. |
Volume: |
26 |
Issue: |
4 |
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1179-89 |
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Publication |
First Author: |
Lopez-Anido C |
Year: |
2016 |
Journal: |
Hum Mol Genet |
Title: |
Tead1 regulates the expression of Peripheral Myelin Protein 22 during Schwann cell development. |
Volume: |
25 |
Issue: |
14 |
Pages: |
3055-3069 |
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Publication |
First Author: |
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Year: |
2019 |
Journal: |
Nat Commun |
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NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies. |
Volume: |
10 |
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1 |
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1467 |
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Year: |
2016 |
Journal: |
PLoS Genet |
Title: |
Tuning PAK Activity to Rescue Abnormal Myelin Permeability in HNPP. |
Volume: |
12 |
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9 |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|