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Search results 1 to 100 out of 313 for Pms2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Baker SM
Year: 1995
Journal: Cell
Title: Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis.
Volume: 82
Issue: 2
Pages: 309-19
Gene
Type: gene
Organism: human
Cell Line Derivation
Derivation Type: Gene trapped
Name: CMHD Gene Trap Library GTL_R1_pMS2
Creator: CMHD
Vector Type: Not Specified
Vector: pMS2
Publication
First Author: Xu XS
Year: 2001
Journal: Cancer Res
Title: Hypermutability to ionizing radiation in mismatch repair-deficient, Pms2 knockout mice.
Volume: 61
Issue: 9
Pages: 3775-80
Publication  
First Author: Fischer JM
Year: 2016
Journal: DNA Repair (Amst)
Title: An intact Pms2 ATPase domain is not essential for male fertility.
Volume: 39
Pages: 46-51
Publication
First Author: van Oers JM
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance.
Volume: 107
Issue: 30
Pages: 13384-9
Publication
First Author: Palmer N
Year: 2023
Journal: PLoS One
Title: Identification PMS1 and PMS2 as potential meiotic substrates of CDK2 activity.
Volume: 18
Issue: 3
Pages: e0283590
Publication
First Author: Marinovic-Terzic I
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q.
Volume: 105
Issue: 37
Pages: 13993-8
Publication
First Author: Bourn RL
Year: 2012
Journal: PLoS One
Title: Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues.
Volume: 7
Issue: 10
Pages: e47085
Publication
First Author: Prolla TA
Year: 1998
Journal: Nat Genet
Title: Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair.
Volume: 18
Issue: 3
Pages: 276-9
Publication
First Author: Biswas K
Year: 2021
Journal: Cell Death Dis
Title: A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing.
Volume: 12
Issue: 9
Pages: 838
Publication
First Author: Chen PC
Year: 2005
Journal: Cancer Res
Title: Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse.
Volume: 65
Issue: 19
Pages: 8662-70
Publication
First Author: Dobrovolsky VN
Year: 2003
Journal: Mutagenesis
Title: Pms2 deficiency results in increased mutation in the Hprt gene but not the Tk gene of Tk(+/-) transgenic mice.
Volume: 18
Issue: 4
Pages: 365-70
Publication
First Author: Qin X
Year: 1999
Journal: Oncogene
Title: Mice defective in the DNA mismatch gene PMS2 are hypersensitive to MNU induced thymic lymphoma and are partially protected by transgenic expression of human MGMT.
Volume: 18
Issue: 30
Pages: 4394-400
Publication
First Author: Shin-Darlak CY
Year: 2005
Journal: DNA Repair (Amst)
Title: A role for Pms2 in the prevention of tandem CC --> TT substitutions induced by ultraviolet radiation and oxidative stress.
Volume: 4
Issue: 1
Pages: 51-7
Publication
First Author: Girelli Zubani G
Year: 2017
Journal: J Exp Med
Title: Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs.
Volume: 214
Issue: 4
Pages: 1169-1180
Publication
First Author: Schrader CE
Year: 2002
Journal: J Exp Med
Title: Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions.
Volume: 195
Issue: 3
Pages: 367-73
Protein
Organism: Mus musculus/domesticus
Length: 859  
Fragment?: false
Gene
Type: gene
Organism: chimpanzee
Publication
First Author: Cascalho M
Year: 1998
Journal: Science
Title: Mismatch repair co-opted by hypermutation.
Volume: 279
Issue: 5354
Pages: 1207-10
Publication
First Author: Ehrenstein MR
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination.
Volume: 98
Issue: 25
Pages: 14553-8
Publication
First Author: Baker SM
Year: 1998
Journal: Cancer Res
Title: Enhanced intestinal adenomatous polyp formation in Pms2-/-;Min mice.
Volume: 58
Issue: 6
Pages: 1087-9
Publication
First Author: Qin J
Year: 2002
Journal: J Hered
Title: Evidence for the lack of mismatch-repair directed antirecombination during mouse meiosis.
Volume: 93
Issue: 3
Pages: 201-5
Publication
First Author: Baross-Francis A
Year: 2000
Journal: Carcinogenesis
Title: Tumors arising in DNA mismatch repair-deficient mice show a wide variation in mutation frequency as assessed by a transgenic reporter gene.
Volume: 21
Issue: 6
Pages: 1259-62
Publication
First Author: Gurtu VE
Year: 2002
Journal: Genetics
Title: Maternal effect for DNA mismatch repair in the mouse.
Volume: 160
Issue: 1
Pages: 271-7
Publication
First Author: Larson JS
Year: 2004
Journal: Mutat Res
Title: Impact of mismatch repair deficiency on genomic stability in the maternal germline and during early embryonic development.
Volume: 556
Issue: 1-2
Pages: 45-53
Publication
First Author: Siegl-Cachedenier I
Year: 2007
Journal: Genes Dev
Title: Deficient mismatch repair improves organismal fitness and survival of mice with dysfunctional telomeres.
Volume: 21
Issue: 17
Pages: 2234-47
Publication
First Author: Narayanan L
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2.
Volume: 94
Issue: 7
Pages: 3122-7
Publication
First Author: Zivojnovic M
Year: 2014
Journal: Mol Cell Biol
Title: Somatic hypermutation at A/T-rich oligonucleotide substrates shows different strand polarities in Ung-deficient or -proficient backgrounds.
Volume: 34
Issue: 12
Pages: 2176-87
Publication
First Author: Miller AJ
Year: 2008
Journal: Nat Methods
Title: Tractable Cre-lox system for stochastic alteration of genes in mice.
Volume: 5
Issue: 3
Pages: 227-9
Publication
First Author: Qin X
Year: 2000
Journal: Carcinogenesis
Title: Heterozygous DNA mismatch repair gene PMS2-knockout mice are susceptible to intestinal tumor induction with N-methyl-N-nitrosourea.
Volume: 21
Issue: 4
Pages: 833-8
Publication
First Author: Yao X
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Different mutator phenotypes in Mlh1- versus Pms2-deficient mice.
Volume: 96
Issue: 12
Pages: 6850-5
Publication
First Author: Baross-Francis A
Year: 2001
Journal: Oncogene
Title: Elevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells.
Volume: 20
Issue: 5
Pages: 619-25
Publication
First Author: Zeng M
Year: 2000
Journal: Cancer Res
Title: Ionizing radiation-induced apoptosis via separate Pms2- and p53-dependent pathways.
Volume: 60
Issue: 17
Pages: 4889-93
Publication
First Author: Schrader CE
Year: 1999
Journal: J Exp Med
Title: Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes.
Volume: 190
Issue: 3
Pages: 323-30
Publication
First Author: Andrew SE
Year: 2000
Journal: Carcinogenesis
Title: Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshifts.
Volume: 21
Issue: 7
Pages: 1291-5
Publication
First Author: Chen PC
Year: 2008
Journal: PLoS Genet
Title: Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.
Volume: 4
Issue: 6
Pages: e1000092
Publication
First Author: Sansom OJ
Year: 2003
Journal: DNA Repair (Amst)
Title: Apoptosis and mutation in the murine small intestine: loss of Mlh1- and Pms2-dependent apoptosis leads to increased mutation in vivo.
Volume: 2
Issue: 9
Pages: 1029-39
Publication
First Author: Fischer JM
Year: 2012
Journal: Oncogene
Title: Different phenotypic consequences of simultaneous versus stepwise Apc loss.
Volume: 31
Issue: 16
Pages: 2028-38
Publication
First Author: Ezzatizadeh V
Year: 2012
Journal: Neurobiol Dis
Title: The mismatch repair system protects against intergenerational GAA repeat instability in a Friedreich ataxia mouse model.
Volume: 46
Issue: 1
Pages: 165-71
Publication
First Author: Kim N
Year: 1999
Journal: J Exp Med
Title: Different mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modifications.
Volume: 190
Issue: 1
Pages: 21-30
Publication
First Author: Fischer JM
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Single cell lineage tracing reveals a role for TgfβR2 in intestinal stem cell dynamics and differentiation.
Volume: 113
Issue: 43
Pages: 12192-12197
Publication
First Author: Fischer JM
Year: 2014
Journal: Carcinogenesis
Title: Occult progression by Apc-deficient intestinal crypts as a target for chemoprevention.
Volume: 35
Issue: 1
Pages: 237-46
Protein
Organism: Mus musculus/domesticus
Length: 191  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Czochor JR
Year: 2016
Journal: Mol Cancer Res
Title: miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expression and Activating Error-Prone DSB Repair.
Volume: 14
Issue: 4
Pages: 363-73
Publication
First Author: Nicolaides NC
Year: 1994
Journal: Nature
Title: Mutations of two PMS homologues in hereditary nonpolyposis colon cancer.
Volume: 371
Issue: 6492
Pages: 75-80
Publication
First Author: Hamilton SR
Year: 1995
Journal: N Engl J Med
Title: The molecular basis of Turcot's syndrome.
Volume: 332
Issue: 13
Pages: 839-47
GXD Expression
Probe: MGI:3585237
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585766
Age: postnatal day 2-3
Image: P2/3
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3585237
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585766
Age: postnatal day 4-5
Image: P4/5
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3585237
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585766
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3585237
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585766
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3585237
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585766
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3585237
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585766
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:3585237
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1716828
Pattern: Uniform
Stage: TS28
Assay Id: MGI:3585766
Age: postnatal adult
Note: Expression was panretinal.
Specimen Label: Adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3585237
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585766
Age: postnatal day 6
Specimen Label: CNS
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Present
Sex: Male
Emaps: EMAPS:3589622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5829796
Age: embryonic day 14.5
Image: 7M
Specimen Label: 7M
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Present
Sex: Male
Emaps: EMAPS:3090722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5829796
Age: embryonic day 14.5
Image: 7M
Specimen Label: 7M
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Present
Sex: Male
Emaps: EMAPS:3589625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5829796
Age: embryonic day 17.5
Image: 7N
Specimen Label: 7N
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Present
Sex: Male
Emaps: EMAPS:2870325
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5829796
Age: embryonic day 17.5
Image: 7N
Specimen Label: 7N
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Present
Sex: Male
Emaps: EMAPS:3589628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5829796
Age: postnatal day 5
Image: 7O
Specimen Label: 7O
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Present
Sex: Female
Emaps: EMAPS:3589622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5829796
Age: embryonic day 14.5
Image: 7P
Specimen Label: 7P
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Present
Sex: Female
Emaps: EMAPS:3090722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5829796
Age: embryonic day 14.5
Image: 7P
Specimen Label: 7P
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Present
Sex: Female
Emaps: EMAPS:2876525
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5829796
Age: embryonic day 17.5
Image: 7Q
Specimen Label: 7Q
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Present
Sex: Female
Emaps: EMAPS:3589625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5829796
Age: embryonic day 17.5
Image: 7Q
Specimen Label: 7Q
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Present
Sex: Female
Emaps: EMAPS:3589628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5829796
Age: postnatal day 5
Image: 7R
Specimen Label: 7R
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Ambiguous
Sex: Male
Emaps: EMAPS:2870328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5829796
Age: postnatal day 5
Image: 7O
Note: Staining in urethral mesenchyme dissipates by P5.
Specimen Label: 7O
Specimen Num: 3
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Ambiguous
Sex: Female
Emaps: EMAPS:2876528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5829796
Age: postnatal day 5
Image: 7R
Note: Staining in urethral mesenchyme dissipates by P5.
Specimen Label: 7R
Specimen Num: 6
GXD Expression    
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Weak
Sex: Male
Emaps: EMAPS:3090522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5829796
Age: embryonic day 14.5
Specimen Label: Supplementary Table E14.5 male
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Moderate
Sex: Male
Emaps: EMAPS:3090322
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:5829796
Age: embryonic day 14.5
Note: Medium expression was detected in muscularis propria. Low expression was detected in lamina propria, muscularis mucosa, and submucosa.
Specimen Label: Supplementary Table E14.5 male
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Moderate
Sex: Male
Emaps: EMAPS:3610222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:5829796
Age: embryonic day 14.5
Specimen Label: Supplementary Table E14.5 male
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5829714
Assay Type: RNA in situ
Annotation Date: 2017-03-29
Strength: Absent
Sex: Male
Emaps: EMAPS:3273522
Stage: TS22
Assay Id: MGI:5829796
Age: embryonic day 14.5
Note: No staining was detected in the neural crest derivatives of the pelvic urethra.
Specimen Label: Supplementary Table E14.5 male
Detected: false
Specimen Num: 7