Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
Patatin-like phospholipase domain-containing protein 2 (PNPLA2) plays a key role in hydrolysis of stored triacylglecerols and is also known as adipose triglyceride lipase (ATGL) []. Members of this family share a patatin domain, initially discovered in potato tubers [, ]. ATGL is expressed in white and brown adipose tissue in high mRNA levels. Mutations in PNPLA2 encoding adipose triglyceride lipase (ATGL) leads to neutral lipid storage disease (NLSD) which is characterized by the accumulation of triglycerides in multiple tissues []. ATGL mutations are also commonly associated with severe forms of skeletal- and cardio-myopathy. ATGL is regulated by insulin []. PNPLA2/ATGL is also known as TTS-2.2 (transport-secretion protein 2.2), iPLA2-zeta (calcium-independent phospholipase A2), and desnutrin [, , ]. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Villena JA |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis. |
Volume: |
279 |
Issue: |
45 |
Pages: |
47066-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zimmermann R |
Year: |
2004 |
Journal: |
Science |
Title: |
Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase. |
Volume: |
306 |
Issue: |
5700 |
Pages: |
1383-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hara M |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle. |
Volume: |
42 |
Issue: |
2 |
Pages: |
112091 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu JW |
Year: |
2017 |
Journal: |
PLoS Genet |
Title: |
Epistatic interaction between the lipase-encoding genes Pnpla2 and Lipe causes liposarcoma in mice. |
Volume: |
13 |
Issue: |
5 |
Pages: |
e1006716 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schweiger M |
Year: |
2009 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5. |
Volume: |
297 |
Issue: |
2 |
Pages: |
E289-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chakrabarti P |
Year: |
2011 |
Journal: |
Curr Diabetes Rev |
Title: |
Adipose triglyceride lipase: a new target in the regulation of lipolysis by insulin. |
Volume: |
7 |
Issue: |
4 |
Pages: |
270-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jenkins CM |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. |
Volume: |
279 |
Issue: |
47 |
Pages: |
48968-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao JG |
Year: |
2007 |
Journal: |
Biochem Biophys Res Commun |
Title: |
A comparative study of human GS2, its paralogues, and its rat orthologue. |
Volume: |
360 |
Issue: |
2 |
Pages: |
501-6 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
486
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kienesberger PC |
Year: |
2009 |
Journal: |
J Lipid Res |
Title: |
Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions. |
Volume: |
50 Suppl |
|
Pages: |
S63-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilson PA |
Year: |
2006 |
Journal: |
J Lipid Res |
Title: |
Characterization of the human patatin-like phospholipase family. |
Volume: |
47 |
Issue: |
9 |
Pages: |
1940-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sitnick MT |
Year: |
2013 |
Journal: |
Diabetes |
Title: |
Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity. |
Volume: |
62 |
Issue: |
10 |
Pages: |
3350-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Etschmaier K |
Year: |
2011 |
Journal: |
J Neurochem |
Title: |
Adipose triglyceride lipase affects triacylglycerol metabolism at brain barriers. |
Volume: |
119 |
Issue: |
5 |
Pages: |
1016-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Z |
Year: |
2022 |
Journal: |
Elife |
Title: |
Lipolysis of bone marrow adipocytes is required to fuel bone and the marrow niche during energy deficits. |
Volume: |
11 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yue F |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Lipid droplet dynamics regulate adult muscle stem cell fate. |
Volume: |
38 |
Issue: |
3 |
Pages: |
110267 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim KH |
Year: |
2023 |
Journal: |
EMBO Rep |
Title: |
PRMT5 links lipid metabolism to contractile function of skeletal muscles. |
Volume: |
24 |
Issue: |
8 |
Pages: |
e57306 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bullock J |
Year: |
2021 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R). |
Volume: |
62 |
Issue: |
2 |
Pages: |
30 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
601
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaltenecker D |
Year: |
2017 |
Journal: |
Diabetologia |
Title: |
Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice. |
Volume: |
60 |
Issue: |
2 |
Pages: |
296-305 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Haemmerle G |
Year: |
2006 |
Journal: |
Science |
Title: |
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. |
Volume: |
312 |
Issue: |
5774 |
Pages: |
734-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beller M |
Year: |
2008 |
Journal: |
PLoS Biol |
Title: |
COPI complex is a regulator of lipid homeostasis. |
Volume: |
6 |
Issue: |
11 |
Pages: |
e292 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu JW |
Year: |
2011 |
Journal: |
Hepatology |
Title: |
Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis. |
Volume: |
54 |
Issue: |
1 |
Pages: |
122-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu JW |
Year: |
2012 |
Journal: |
Endocrinology |
Title: |
Fasting energy homeostasis in mice with adipose deficiency of desnutrin/adipose triglyceride lipase. |
Volume: |
153 |
Issue: |
5 |
Pages: |
2198-207 |
|
•
•
•
•
•
|
Publication |
First Author: |
Salatzki J |
Year: |
2018 |
Journal: |
PLoS Genet |
Title: |
Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure. |
Volume: |
14 |
Issue: |
1 |
Pages: |
e1007171 |
|
•
•
•
•
•
|
Publication |
First Author: |
Foryst-Ludwig A |
Year: |
2015 |
Journal: |
J Biol Chem |
Title: |
Adipose Tissue Lipolysis Promotes Exercise-induced Cardiac Hypertrophy Involving the Lipokine C16:1n7-Palmitoleate. |
Volume: |
290 |
Issue: |
39 |
Pages: |
23603-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Romero AR |
Year: |
2022 |
Journal: |
iScience |
Title: |
Adipose triglyceride lipase mediates lipolysis and lipid mobilization in response to iron-mediated negative energy balance. |
Volume: |
25 |
Issue: |
3 |
Pages: |
103941 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dubé JJ |
Year: |
2015 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Adipose triglyceride lipase deletion from adipocytes, but not skeletal myocytes, impairs acute exercise performance in mice. |
Volume: |
308 |
Issue: |
10 |
Pages: |
E879-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boutagy NE |
Year: |
2024 |
Journal: |
J Clin Invest |
Title: |
Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice. |
Volume: |
134 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kaur S |
Year: |
2021 |
Journal: |
Clin Transl Med |
Title: |
Adipose-specific ATGL ablation reduces burn injury-induced metabolic derangements in mice. |
Volume: |
11 |
Issue: |
6 |
Pages: |
e417 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lin Y |
Year: |
2013 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Vascular smooth muscle cells isolated from adipose triglyceride lipase-deficient mice exhibit distinct phenotype and phenotypic plasticity. |
Volume: |
434 |
Issue: |
3 |
Pages: |
534-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peyot ML |
Year: |
2009 |
Journal: |
J Biol Chem |
Title: |
Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion. |
Volume: |
284 |
Issue: |
25 |
Pages: |
16848-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hoy AJ |
Year: |
2011 |
Journal: |
Endocrinology |
Title: |
Adipose triglyceride lipase-null mice are resistant to high-fat diet-induced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation. |
Volume: |
152 |
Issue: |
1 |
Pages: |
48-58 |
|
•
•
•
•
•
|
Publication |
First Author: |
Al-Zoughbi W |
Year: |
2016 |
Journal: |
Oncotarget |
Title: |
Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia. |
Volume: |
7 |
Issue: |
23 |
Pages: |
33832-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Coelho M |
Year: |
2015 |
Journal: |
J Diabetes Res |
Title: |
Effect of Global ATGL Knockout on Murine Fasting Glucose Kinetics. |
Volume: |
2015 |
|
Pages: |
542029 |
|
•
•
•
•
•
|
Publication |
First Author: |
MacPherson RE |
Year: |
2016 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Reduced ATGL-mediated lipolysis attenuates β-adrenergic-induced AMPK signaling, but not the induction of PKA-targeted genes, in adipocytes and adipose tissue. |
Volume: |
311 |
Issue: |
2 |
Pages: |
C269-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schrammel A |
Year: |
2013 |
Journal: |
Biochim Biophys Acta |
Title: |
Cardiac oxidative stress in a mouse model of neutral lipid storage disease. |
Volume: |
1831 |
Issue: |
11 |
Pages: |
1600-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
van de Weijer T |
Year: |
2012 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Geometrical models for cardiac MRI in rodents: comparison of quantification of left ventricular volumes and function by various geometrical models with a full-volume MRI data set in rodents. |
Volume: |
302 |
Issue: |
3 |
Pages: |
H709-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schlager S |
Year: |
2015 |
Journal: |
J Leukoc Biol |
Title: |
Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis. |
Volume: |
98 |
Issue: |
5 |
Pages: |
837-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suriben R |
Year: |
2020 |
Journal: |
Nat Med |
Title: |
Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice. |
Volume: |
26 |
Issue: |
8 |
Pages: |
1264-1270 |
|
•
•
•
•
•
|
Publication |
First Author: |
Masaki H |
Year: |
2017 |
Journal: |
Mol Hum Reprod |
Title: |
Long-chain fatty acid triglyceride (TG) metabolism disorder impairs male fertility: a study using adipose triglyceride lipase deficient mice. |
Volume: |
23 |
Issue: |
7 |
Pages: |
452-460 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paluchova V |
Year: |
2020 |
Journal: |
Diabetes |
Title: |
Lipokine 5-PAHSA Is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for De Novo Lipogenesis in Mice. |
Volume: |
69 |
Issue: |
3 |
Pages: |
300-312 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chandak PG |
Year: |
2010 |
Journal: |
J Biol Chem |
Title: |
Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase. |
Volume: |
285 |
Issue: |
26 |
Pages: |
20192-201 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chitraju C |
Year: |
2013 |
Journal: |
J Lipid Res |
Title: |
The impact of genetic stress by ATGL deficiency on the lipidome of lipid droplets from murine hepatocytes. |
Volume: |
54 |
Issue: |
8 |
Pages: |
2185-2194 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goeritzer M |
Year: |
2022 |
Journal: |
Cells |
Title: |
Adipose Triglyceride Lipase Deficiency Attenuates In Vitro Thrombus Formation without Affecting Platelet Activation and Bleeding In Vivo. |
Volume: |
11 |
Issue: |
5 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Schrammel A |
Year: |
2014 |
Journal: |
Biochim Biophys Acta |
Title: |
Endothelial dysfunction in adipose triglyceride lipase deficiency. |
Volume: |
1841 |
Issue: |
6 |
Pages: |
906-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schreiber R |
Year: |
2015 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity. |
Volume: |
112 |
Issue: |
45 |
Pages: |
13850-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen W |
Year: |
2017 |
Journal: |
FEBS J |
Title: |
Atgl deficiency induces podocyte apoptosis and leads to glomerular filtration barrier damage. |
Volume: |
284 |
Issue: |
7 |
Pages: |
1070-1081 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schoiswohl G |
Year: |
2010 |
Journal: |
J Lipid Res |
Title: |
Adipose triglyceride lipase plays a key role in the supply of the working muscle with fatty acids. |
Volume: |
51 |
Issue: |
3 |
Pages: |
490-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aflaki E |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages. |
Volume: |
286 |
Issue: |
9 |
Pages: |
7418-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shook BA |
Year: |
2020 |
Journal: |
Cell Stem Cell |
Title: |
Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair. |
Volume: |
26 |
Issue: |
6 |
Pages: |
880-895.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Attané C |
Year: |
2016 |
Journal: |
Diabetologia |
Title: |
A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice. |
Volume: |
59 |
Issue: |
12 |
Pages: |
2654-2663 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stephenson EJ |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Chronic intake of high dietary sucrose induces sexually dimorphic metabolic adaptations in mouse liver and adipose tissue. |
Volume: |
13 |
Issue: |
1 |
Pages: |
6062 |
|
•
•
•
•
•
|
Publication |
First Author: |
Parajuli N |
Year: |
2018 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Atglistatin ameliorates functional decline in heart failure via adipocyte-specific inhibition of adipose triglyceride lipase. |
Volume: |
315 |
Issue: |
4 |
Pages: |
H879-H884 |
|
•
•
•
•
•
|
Publication |
First Author: |
Patel R |
Year: |
2022 |
Journal: |
Nature |
Title: |
ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids. |
Volume: |
606 |
Issue: |
7916 |
Pages: |
968-975 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mottillo EP |
Year: |
2014 |
Journal: |
J Lipid Res |
Title: |
Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation. |
Volume: |
55 |
Issue: |
11 |
Pages: |
2276-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schoiswohl G |
Year: |
2015 |
Journal: |
Endocrinology |
Title: |
Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice. |
Volume: |
156 |
Issue: |
10 |
Pages: |
3610-24 |
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•
•
•
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Publication |
First Author: |
Zhou C |
Year: |
2023 |
Journal: |
Mol Metab |
Title: |
Sympathetic overdrive and unrestrained adipose lipolysis drive alcohol-induced hepatic steatosis in rodents. |
Volume: |
78 |
|
Pages: |
101813 |
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•
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•
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Publication |
First Author: |
Zhang S |
Year: |
2024 |
Journal: |
J Lipid Res |
Title: |
Acute activation of adipocyte lipolysis reveals dynamic lipid remodeling of the hepatic lipidome. |
Volume: |
65 |
Issue: |
2 |
Pages: |
100434 |
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•
•
•
•
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Publication |
First Author: |
Qiao L |
Year: |
2019 |
Journal: |
Diabetes |
Title: |
Prolonged Prepregnant Maternal High-Fat Feeding Reduces Fetal and Neonatal Blood Glucose Concentrations by Enhancing Fetal β-Cell Development in C57BL/6 Mice. |
Volume: |
68 |
Issue: |
8 |
Pages: |
1604-1613 |
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Publication |
First Author: |
Kienesberger PC |
Year: |
2012 |
Journal: |
Mol Cell Biol |
Title: |
Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction. |
Volume: |
32 |
Issue: |
4 |
Pages: |
740-50 |
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•
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•
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Publication |
First Author: |
Nunes PM |
Year: |
2012 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Increased intramyocellular lipids but unaltered in vivo mitochondrial oxidative phosphorylation in skeletal muscle of adipose triglyceride lipase-deficient mice. |
Volume: |
303 |
Issue: |
1 |
Pages: |
E71-81 |
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•
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•
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Publication |
First Author: |
Fuchs CD |
Year: |
2022 |
Journal: |
Hepatology |
Title: |
Hepatocyte-specific deletion of adipose triglyceride lipase (adipose triglyceride lipase/patatin-like phospholipase domain containing 2) ameliorates dietary induced steatohepatitis in mice. |
Volume: |
75 |
Issue: |
1 |
Pages: |
125-139 |
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•
•
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•
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Publication |
First Author: |
Kurat CF |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast. |
Volume: |
281 |
Issue: |
1 |
Pages: |
491-500 |
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•
•
•
•
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Publication |
First Author: |
Zechner R |
Year: |
2009 |
Journal: |
J Lipid Res |
Title: |
Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores. |
Volume: |
50 |
Issue: |
1 |
Pages: |
3-21 |
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•
•
•
•
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Publication |
First Author: |
Ahmadian M |
Year: |
2009 |
Journal: |
Diabetes |
Title: |
Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity. |
Volume: |
58 |
Issue: |
4 |
Pages: |
855-66 |
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•
•
•
•
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Publication |
First Author: |
Duncan RE |
Year: |
2010 |
Journal: |
J Lipid Res |
Title: |
Characterization of desnutrin functional domains: critical residues for triacylglycerol hydrolysis in cultured cells. |
Volume: |
51 |
Issue: |
2 |
Pages: |
309-17 |
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•
•
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•
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Publication |
First Author: |
Xie X |
Year: |
2014 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Identification of a novel phosphorylation site in adipose triglyceride lipase as a regulator of lipid droplet localization. |
Volume: |
306 |
Issue: |
12 |
Pages: |
E1449-59 |
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•
•
•
•
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Publication |
First Author: |
Meex RC |
Year: |
2015 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
ATGL-mediated triglyceride turnover and the regulation of mitochondrial capacity in skeletal muscle. |
Volume: |
308 |
Issue: |
11 |
Pages: |
E960-70 |
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Publication |
First Author: |
Korbelius M |
Year: |
2022 |
Journal: |
Biochim Biophys Acta Mol Cell Biol Lipids |
Title: |
Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis. |
Volume: |
1867 |
Issue: |
4 |
Pages: |
159121 |
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GXD Expression |
Probe: |
MGI:7384719 |
Assay Type: |
RT-PCR |
Annotation Date: |
2022-11-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1920926 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7384919 |
Age: |
embryonic day 18.5 |
Image: |
5 |
|
Specimen Label: |
+/+ or -/- |
Detected: |
true |
Specimen Num: |
1 |
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