|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 129 for Pnpla3

<< First    < Previous  |  Next >    Last >>
0.047s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Kumari M
Year: 2012
Journal: Cell Metab
Title: Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase.
Volume: 15
Issue: 5
Pages: 691-702
Publication  
First Author: Lindén D
Year: 2019
Journal: Mol Metab
Title: Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice.
Volume: 22
Pages: 49-61
Publication
First Author: Smagris E
Year: 2015
Journal: Hepatology
Title: Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis.
Volume: 61
Issue: 1
Pages: 108-18
Publication
First Author: BasuRay S
Year: 2017
Journal: Hepatology
Title: The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation.
Volume: 66
Issue: 4
Pages: 1111-1124
Publication
First Author: BasuRay S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis.
Volume: 116
Issue: 19
Pages: 9521-9526
Publication
First Author: Baulande S
Year: 2001
Journal: J Biol Chem
Title: Adiponutrin, a transmembrane protein corresponding to a novel dietary- and obesity-linked mRNA specifically expressed in the adipose lineage.
Volume: 276
Issue: 36
Pages: 33336-44
Publication  
First Author: Marmugi A
Year: 2016
Journal: Toxicol Appl Pharmacol
Title: Activation of the Constitutive Androstane Receptor induces hepatic lipogenesis and regulates Pnpla3 gene expression in a LXR-independent way.
Volume: 303
Pages: 90-100
Publication
First Author: Mitsche MA
Year: 2018
Journal: J Biol Chem
Title: Patatin-like phospholipase domain-containing protein 3 promotes transfer of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets.
Volume: 293
Issue: 18
Pages: 6958-6968
Publication
First Author: Li JZ
Year: 2012
Journal: J Clin Invest
Title: Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis.
Volume: 122
Issue: 11
Pages: 4130-44
Protein
Organism: Mus musculus/domesticus
Length: 413  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 384  
Fragment?: false
Publication
First Author: Basantani MK
Year: 2011
Journal: J Lipid Res
Title: Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome.
Volume: 52
Issue: 2
Pages: 318-29
Publication
First Author: Karatayli E
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Effect of alcohol on the interleukin 6-mediated inflammatory response in a new mouse model of acute-on-chronic liver injury.
Volume: 1865
Issue: 2
Pages: 298-307
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_04
Specimen Label: euxassay_006787_04
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_05
Specimen Label: euxassay_006787_05
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_06
Specimen Label: euxassay_006787_06
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_07
Specimen Label: euxassay_006787_07
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_08
Specimen Label: euxassay_006787_08
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_09
Specimen Label: euxassay_006787_09
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_10
Specimen Label: euxassay_006787_10
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_11
Specimen Label: euxassay_006787_11
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_11
Specimen Label: euxassay_006787_11
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_12
Specimen Label: euxassay_006787_12
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_12
Specimen Label: euxassay_006787_12
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_13
Specimen Label: euxassay_006787_13
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1765323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_14
Specimen Label: euxassay_006787_14
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_15
Specimen Label: euxassay_006787_15
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_15
Specimen Label: euxassay_006787_15
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_16
Specimen Label: euxassay_006787_16
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_16
Specimen Label: euxassay_006787_16
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_17
Specimen Label: euxassay_006787_17
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_17
Specimen Label: euxassay_006787_17
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_18
Specimen Label: euxassay_006787_18
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_18
Specimen Label: euxassay_006787_18
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_19
Specimen Label: euxassay_006787_19
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_19
Specimen Label: euxassay_006787_19
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_20
Specimen Label: euxassay_006787_20
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_21
Specimen Label: euxassay_006787_21
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_22
Specimen Label: euxassay_006787_22
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:668413
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1766123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827304
Age: embryonic day 14.5
Image: euxassay_006787_23
Specimen Label: euxassay_006787_23
Detected: true
Specimen Num: 20
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Qiao A
Year: 2011
Journal: Hepatology
Title: Mouse patatin-like phospholipase domain-containing 3 influences systemic lipid and glucose homeostasis.
Volume: 54
Issue: 2
Pages: 509-21
Protein Domain
Type: Family
Description: This family represents PNPLA3 (patatin-like phospholipase domain-containing protein 3) from mammals, also known as ADPN (adiponutrin) or iPLA2-epsilon (calcium-independent phospholipase A2). PNPLA3 is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes and is an indicator of the nutritional state. Human adiponutrins are bound to the cell membrane of adipocytes and show transacylase, TG hydrolase, and PLA2 activity [, , ]. In murine models, PNPLA3 was found to be involved in the hepatic metabolism of triglycerides and in the regulation of systemic glucose homeostasis [].
UniProt Feature
Begin: 1
Description: 1-acylglycerol-3-phosphate O-acyltransferase Pnpla3
Type: chain
End: 413