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Search results 1 to 88 out of 88 for Pnpla8

0.027s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
50640 | PNPLA8
Type: gene
Organism: human
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Gene
100038186 | pnpla8
Type: gene
Organism: frog, western clawed
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Gene
314075 | Pnpla8
Type: gene
Organism: rat
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Gene
472484 | PNPLA8
Type: gene
Organism: chimpanzee
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Gene
475880 | PNPLA8
Type: gene
Organism: dog, domestic
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Gene
535496 | PNPLA8
Type: gene
Organism: cattle
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Gene
417785 | PNPLA8
Type: gene
Organism: chicken
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Gene
100126812 | pnpla8
Type: gene
Organism: zebrafish
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Gene
700851 | PNPLA8
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1914702 | Pnpla8
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
36719796 | J:333442
First Author: Hirabayashi T
Year: 2023
Journal: Cell Rep
Title: Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups.
Volume: 42
Issue: 2
Pages: 111940
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Protein Coding Gene
MGP_CAROLIEiJ_G0017725 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019711 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019675 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019646 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019653 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019457 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1914702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020100 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019429 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019542 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019531 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019612 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019567 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020140 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018777 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019060 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029482 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018567 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
17923475 | J:128989
First Author: Mancuso DJ
Year: 2007
Journal: J Biol Chem
Title: Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype.
Volume: 282
Issue: 48
Pages: 34611-22
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Publication
28442572 | J:246027
First Author: Liu GY
Year: 2017
Journal: J Biol Chem
Title: The phospholipase iPLA2γ is a major mediator releasing oxidized aliphatic chains from cardiolipin, integrating mitochondrial bioenergetics and signaling.
Volume: 292
Issue: 25
Pages: 10672-10684
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Publication
20179248 | J:162883
First Author: Song H
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet.
Volume: 298
Issue: 6
Pages: E1097-114
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Publication
31700134 | J:287002
First Author: Elimam H
Year: 2019
Journal: Sci Rep
Title: Genetic Ablation of Calcium-independent Phospholipase A2γ Exacerbates Glomerular Injury in Adriamycin Nephrosis in Mice.
Volume: 9
Issue: 1
Pages: 16229
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Publication
19840936 | J:158203
First Author: Mancuso DJ
Year: 2009
Journal: J Biol Chem
Title: Genetic ablation of calcium-independent phospholipase A2{gamma} leads to alterations in hippocampal cardiolipin content and molecular species distribution, mitochondrial degeneration, autophagy, and cognitive dysfunction.
Volume: 284
Issue: 51
Pages: 35632-44
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Publication
25313821 | J:223561
First Author: Yoda E
Year: 2014
Journal: PLoS One
Title: Group VIB calcium-independent phospholipase A2 (iPLA2γ) regulates platelet activation, hemostasis and thrombosis in mice.
Volume: 9
Issue: 10
Pages: e109409
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Publication
32161117 | J:286821
First Author: Liu X
Year: 2020
Journal: J Biol Chem
Title: 12-LOX catalyzes the oxidation of 2-arachidonoyl-lysolipids in platelets generating eicosanoid-lysolipids that are attenuated by iPLA2γ knockout.
Volume: 295
Issue: 16
Pages: 5307-5320
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Publication
20625036 | J:165451
First Author: Yoda E
Year: 2010
Journal: J Lipid Res
Title: Mitochondrial dysfunction and reduced prostaglandin synthesis in skeletal muscle of Group VIB Ca2+-independent phospholipase A2gamma-deficient mice.
Volume: 51
Issue: 10
Pages: 3003-15
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Publication
23429536 | J:199736
First Author: Sharma J
Year: 2013
Journal: Infect Immun
Title: The absence of myocardial calcium-independent phospholipase A2γ results in impaired prostaglandin E2 production and decreased survival in mice with acute Trypanosoma cruzi infection.
Volume: 81
Issue: 7
Pages: 2278-87
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Publication
39480824 | J:359130
First Author: Cybulsky AV
Year: 2024
Journal: PLoS One
Title: Genetic deletion of calcium-independent phospholipase A2γ protects mice from diabetic nephropathy.
Volume: 19
Issue: 10
Pages: e0311404
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Publication
27453526 | J:236927
First Author: Moon SH
Year: 2016
Journal: J Biol Chem
Title: Cardiac Myocyte-specific Knock-out of Calcium-independent Phospholipase A2γ (iPLA2γ) Decreases Oxidized Fatty Acids during Ischemia/Reperfusion and Reduces Infarct Size.
Volume: 291
Issue: 37
Pages: 19687-700
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Publication
37275531 | J:341027
First Author: Moon SH
Year: 2023
Journal: iScience
Title: Genetic deletion of skeletal muscle iPLA(2)γ results in mitochondrial dysfunction, muscle atrophy and alterations in whole-body energy metabolism.
Volume: 26
Issue: 6
Pages: 106895
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Publication
17213206 | J:120895
First Author: Mancuso DJ
Year: 2007
Journal: J Biol Chem
Title: Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.
Volume: 282
Issue: 12
Pages: 9216-27
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Publication
20817734 | J:166869
First Author: Mancuso DJ
Year: 2010
Journal: J Biol Chem
Title: Genetic ablation of calcium-independent phospholipase A2gamma prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation.
Volume: 285
Issue: 47
Pages: 36495-510
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Publication
26206229 | J:226333
First Author: Rauckhorst AJ
Year: 2015
Journal: FEBS Lett
Title: The iPLA(2)γ is identified as the membrane potential sensitive phospholipase in liver mitochondria.
Volume: 589
Issue: 18
Pages: 2367-71
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Publication
21191104 | J:171167
First Author: Sharma J
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: Activation of group VI phospholipase A2 isoforms in cardiac endothelial cells.
Volume: 300
Issue: 4
Pages: C872-9
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Publication
22389508 | J:184885
First Author: Moon SH
Year: 2012
Journal: J Biol Chem
Title: Activation of mitochondrial calcium-independent phospholipase A2γ (iPLA2γ) by divalent cations mediating arachidonate release and production of downstream eicosanoids.
Volume: 287
Issue: 18
Pages: 14880-95
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Publication
22778252 | J:190421
First Author: Moon SH
Year: 2012
Journal: J Biol Chem
Title: Genetic ablation of calcium-independent phospholipase A(2)γ (iPLA(2)γ) attenuates calcium-induced opening of the mitochondrial permeability transition pore and resultant cytochrome c release.
Volume: 287
Issue: 35
Pages: 29837-50
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Publication
25492867 | J:219357
First Author: Elimam H
Year: 2015
Journal: J Biol Chem
Title: Calcium-independent phospholipase A2γ enhances activation of the ATF6 transcription factor during endoplasmic reticulum stress.
Volume: 290
Issue: 5
Pages: 3009-20
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Publication
27226532 | J:235458
First Author: Elimam H
Year: 2016
Journal: J Biol Chem
Title: Genetic Ablation of Calcium-independent Phospholipase A2γ Induces Glomerular Injury in Mice.
Volume: 291
Issue: 28
Pages: 14468-82
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Publication
29035365 | J:254385
First Author: Shimanaka Y
Year: 2017
Journal: Nat Med
Title: Omega-3 fatty acid epoxides are autocrine mediators that control the magnitude of IgE-mediated mast cell activation.
Volume: 23
Issue: 11
Pages: 1287-1297
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
15908428 | -
First Author: Yan W
Year: 2005
Journal: J Biol Chem
Title: The highly selective production of 2-arachidonoyl lysophosphatidylcholine catalyzed by purified calcium-independent phospholipase A2gamma: identification of a novel enzymatic mediator for the generation of a key branch point intermediate in eicosanoid signaling.
Volume: 280
Issue: 29
Pages: 26669-79
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Publication
17475618 | -
First Author: Yang W
Year: 2007
Journal: J Biol Chem
Title: AtPLAI is an acyl hydrolase involved in basal jasmonic acid production and Arabidopsis resistance to Botrytis cinerea.
Volume: 282
Issue: 25
Pages: 18116-18128
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Protein Domain
IPR045217 | PNPLA8-like
Type: Domain
Description: Patatin-like phospholipase domain containing protein 8 (PNPLA8, also known as iPLA2-gamma) is a Ca-independent myocardial phospholipase which maintains mitochondrial integrity. In humans, it is predominantly expressed in heart tissue. iPLA2-gamma can catalyse both phospholipase A1 and A2 reactions (PLA1 and PLA2 respectively). This family includes PNPLA8 (iPLA2-gamma) from mammals [, , ]and AtPLAI from Arabidopsis [].
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Protein
Q8K1N1
Organism: Mus musculus/domesticus
Length: 776  
Fragment?: false
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Protein
E9PXB0
Organism: Mus musculus/domesticus
Length: 558  
Fragment?: false
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Protein
E9QAC9
Organism: Mus musculus/domesticus
Length: 711  
Fragment?: false
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Publication
19029121 | -
 
First Author: Kienesberger PC
Year: 2009
Journal: J Lipid Res
Title: Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions.
Volume: 50 Suppl
Pages: S63-8
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Publication
16799181 | -
First Author: Wilson PA
Year: 2006
Journal: J Lipid Res
Title: Characterization of the human patatin-like phospholipase family.
Volume: 47
Issue: 9
Pages: 1940-9
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