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Search results 1 to 100 out of 147 for Polh

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Type Details Score
Gene
5429 | POLH
Type: gene
Organism: human
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Gene
513606 | POLH
Type: gene
Organism: cattle
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Gene
395102 | POLH
Type: gene
Organism: chicken
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Gene
678520 | polh
Type: gene
Organism: zebrafish
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Gene
700772 | POLH
Type: gene
Organism: macaque, rhesus
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Gene
100487374 | polh
Type: gene
Organism: frog, western clawed
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Gene
316235 | Polh
Type: gene
Organism: rat
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Gene
474915 | POLH
Type: gene
Organism: dog, domestic
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Gene
462720 | POLH
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1891457 | Polh
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
111216283 | POLH-AS1
Type: gene
Organism: human
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Publication
22223762 | J:182567
First Author: Kano C
Year: 2012
Journal: Int Immunol
Title: Analysis of mice deficient in both REV1 catalytic activity and POLH reveals an unexpected role for POLH in the generation of C to G and G to C transversions during Ig gene hypermutation.
Volume: 24
Issue: 3
Pages: 169-74
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Publication
18825746 | J:143471
First Author: Masuda K
Year: 2008
Journal: Eur J Immunol
Title: DNA polymerase eta is a limiting factor for A:T mutations in Ig genes and contributes to antibody affinity maturation.
Volume: 38
Issue: 10
Pages: 2796-805
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Publication
17449470 | J:122996
First Author: Masuda K
Year: 2007
Journal: J Biol Chem
Title: DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes.
Volume: 282
Issue: 24
Pages: 17387-94
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Publication
17015482 | J:115000
First Author: Ohkumo T
Year: 2006
Journal: Mol Cell Biol
Title: UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota.
Volume: 26
Issue: 20
Pages: 7696-706
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Publication
22960197 | J:188285
First Author: Li S
Year: 2013
Journal: Mol Immunol
Title: Analysis of Ig gene hypermutation in Ung(-/-)Polh(-/-) mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions.
Volume: 53
Issue: 3
Pages: 214-7
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Protein Coding Gene
MGP_CAROLIEiJ_G0021660 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023805 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023763 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023734 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023767 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023531 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1891457 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024210 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023012 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023507 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0023633 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023600 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023714 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0023629 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024255 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022757 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023077 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0020652 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0022572 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10871396 | J:63288
First Author: Yamada A
Year: 2000
Journal: Nucleic Acids Res
Title: Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase eta.
Volume: 28
Issue: 13
Pages: 2473-80
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Publication
16397220 | J:105034
First Author: Lin Q
Year: 2006
Journal: Cancer Res
Title: Increased susceptibility to UV-induced skin carcinogenesis in polymerase eta-deficient mice.
Volume: 66
Issue: 1
Pages: 87-94
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Publication
16585153 | J:108222
First Author: Hagendoorn J
Year: 2006
Journal: Cancer Res
Title: Onset of abnormal blood and lymphatic vessel function and interstitial hypertension in early stages of carcinogenesis.
Volume: 66
Issue: 7
Pages: 3360-4
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Publication
26240351 | J:226564
First Author: Chen YW
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities.
Volume: 112
Issue: 33
Pages: E4556-64
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Publication
18381412 | J:133309
First Author: Busuttil RA
Year: 2008
Journal: Cancer Res
Title: Mutation frequencies and spectra in DNA polymerase eta-deficient mice.
Volume: 68
Issue: 7
Pages: 2081-4
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Publication
15939880 | J:99721
First Author: Martomo SA
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification.
Volume: 102
Issue: 24
Pages: 8656-61
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2153448
Age: postnatal adult
Specimen Label: heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2153448
Age: postnatal adult
Specimen Label: brain
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2153448
Age: postnatal adult
Specimen Label: spleen
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2153448
Age: postnatal adult
Specimen Label: lung
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2153448
Age: postnatal adult
Specimen Label: liver
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2153448
Age: postnatal adult
Specimen Label: skeletal muscle
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2153448
Age: postnatal adult
Specimen Label: kidney
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2153448
Age: postnatal adult
Specimen Label: testis
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2153450
Age: postnatal adult
Specimen Label: spleen
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2153450
Age: postnatal adult
Specimen Label: thymus
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2153450
Age: postnatal adult
Specimen Label: liver
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2153450
Age: postnatal adult
Specimen Label: lung
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2153450
Age: postnatal adult
Specimen Label: testis
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2152956
Assay Type: Northern blot
Annotation Date: 2001-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:2153450
Age: postnatal adult
Specimen Label: skin
Detected: true
Specimen Num: 6
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Publication
18485835 | J:138141
First Author: Martomo SA
Year: 2008
Journal: DNA Repair (Amst)
Title: Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.
Volume: 7
Issue: 9
Pages: 1603-8
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Publication
22615128 | J:189124
First Author: Saribasak H
Year: 2012
Journal: J Exp Med
Title: DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions.
Volume: 209
Issue: 6
Pages: 1075-81
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Publication
27481099 | J:276485
 
First Author: Fritzen R
Year: 2016
Journal: DNA Repair (Amst)
Title: A single aspartate mutation in the conserved catalytic site of Rev3L generates a hypomorphic phenotype in vivo and in vitro.
Volume: 46
Pages: 37-46
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Publication
19414788 | J:150294
First Author: Faili A
Year: 2009
Journal: J Immunol
Title: A backup role of DNA polymerase kappa in Ig gene hypermutation only takes place in the complete absence of DNA polymerase eta.
Volume: 182
Issue: 10
Pages: 6353-9
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Publication
17114294 | J:117079
First Author: Dumstorf CA
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer.
Volume: 103
Issue: 48
Pages: 18083-8
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Publication
16443401 | J:107217
First Author: Martomo SA
Year: 2006
Journal: DNA Repair (Amst)
Title: Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota.
Volume: 5
Issue: 3
Pages: 392-8
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Publication
15824086 | J:98037
First Author: Delbos F
Year: 2005
Journal: J Exp Med
Title: Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse.
Volume: 201
Issue: 8
Pages: 1191-6
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Publication
26727495 | J:232141
First Author: Lange SS
Year: 2016
Journal: PLoS Genet
Title: The Polymerase Activity of Mammalian DNA Pol ζ Is Specifically Required for Cell and Embryonic Viability.
Volume: 12
Issue: 1
Pages: e1005759
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Publication
22733395 | J:193520
First Author: Brun J
Year: 2013
Journal: Int J Cancer
Title: Oncolytic Vaccinia virus safely and effectively treats skin tumors in mouse models of xeroderma pigmentosum.
Volume: 132
Issue: 3
Pages: 726-31
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Publication
17190840 | J:125298
First Author: Delbos F
Year: 2007
Journal: J Exp Med
Title: DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse.
Volume: 204
Issue: 1
Pages: 17-23
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Publication
22244149 | J:203607
First Author: Ito W
Year: 2012
Journal: Genes Cells
Title: Stalled Polη at its cognate substrate initiates an alternative translesion synthesis pathway via interaction with REV1.
Volume: 17
Issue: 2
Pages: 98-108
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Publication
14657033 | J:87113
First Author: Guo C
Year: 2003
Journal: EMBO J
Title: Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis.
Volume: 22
Issue: 24
Pages: 6621-30
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Publication
10856884 | J:59222
First Author: Dai G
Year: 2000
Journal: J Endocrinol
Title: Three novel paralogs of the rodent prolactin gene family.
Volume: 166
Issue: 1
Pages: 63-75
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Publication
27694478 | J:268403
First Author: Zhou L
Year: 2017
Journal: FASEB J
Title: Role of FEN1 S187 phosphorylation in counteracting oxygen-induced stress and regulating postnatal heart development.
Volume: 31
Issue: 1
Pages: 132-147
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Protein
I6L9K1
Organism: Mus musculus/domesticus
Length: 556  
Fragment?: false
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Pathway
R-MMU-110320 | Translesion Synthesis by POLH
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Allele
Polh<em1Smoc> | MGI:7291749
Name: polymerase (DNA directed), eta (RAD 30 related); endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Polh<tm1.1Rak> | MGI:3614412
Name: polymerase (DNA directed), eta (RAD 30 related); targeted mutation 1.1, Raju Kucherlapati
Allele Type: Targeted
Attribute String: Null/knockout
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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