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Search results 1 to 100 out of 146 for Polq

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
10721 | POLQ
Type: gene
Organism: human
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Gene
535323 | POLQ
Type: gene
Organism: cattle
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Gene
418326 | POLQ
Type: gene
Organism: chicken
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Gene
566079 | polq
Type: gene
Organism: zebrafish
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Gene
713828 | POLQ
Type: gene
Organism: macaque, rhesus
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Gene
733897 | polq
Type: gene
Organism: frog, western clawed
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Gene
288079 | Polq
Type: gene
Organism: rat
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Gene
488003 | POLQ
Type: gene
Organism: dog, domestic
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Gene
460619 | POLQ
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2155399 | Polq
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
113510 | HELQ
Type: gene
Organism: human
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Publication
21883722 | J:189375
First Author: Li Y
Year: 2011
Journal: Genes Cells
Title: Comparison of two POLQ mutants reveals that a polymerase-inactive POLQ retains significant function in tolerance to etoposide and γ-irradiation in mouse B cells.
Volume: 16
Issue: 9
Pages: 973-83
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Publication
15542845 | J:94088
First Author: Shima N
Year: 2004
Journal: Mol Cell Biol
Title: The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm.
Volume: 24
Issue: 23
Pages: 10381-9
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Publication
12663541 | J:82700
First Author: Shima N
Year: 2003
Journal: Genetics
Title: Phenotype-based identification of mouse chromosome instability mutants.
Volume: 163
Issue: 3
Pages: 1031-40
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Publication
16890500 | J:115989
First Author: Masuda K
Year: 2006
Journal: DNA Repair (Amst)
Title: Absence of DNA polymerase theta results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes.
Volume: 5
Issue: 11
Pages: 1384-91
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Publication
25642960 | J:219558
First Author: Mateos-Gomez PA
Year: 2015
Journal: Nature
Title: Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.
Volume: 518
Issue: 7538
Pages: 254-7
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Publication
29079701 | J:258323
First Author: Schimmel J
Year: 2017
Journal: EMBO J
Title: Mutational signatures of non-homologous and polymerase theta-mediated end-joining in embryonic stem cells.
Volume: 36
Issue: 24
Pages: 3634-3649
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Publication
25275444 | J:243811
First Author: Yousefzadeh MJ
Year: 2014
Journal: PLoS Genet
Title: Mechanism of suppression of chromosomal instability by DNA polymerase POLQ.
Volume: 10
Issue: 10
Pages: e1004654
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Publication
17449470 | J:122996
First Author: Masuda K
Year: 2007
Journal: J Biol Chem
Title: DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes.
Volume: 282
Issue: 24
Pages: 17387-94
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Publication
25642963 | J:219787
First Author: Ceccaldi R
Year: 2015
Journal: Nature
Title: Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair.
Volume: 518
Issue: 7538
Pages: 258-62
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Protein Coding Gene
MGP_CAROLIEiJ_G0020725 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0022798 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0022763 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0022735 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0022764 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0022528 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2155399 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0023211 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0022054 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0022499 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022631 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0022606 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0022699 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0022625 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0023226 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0021794 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0022098 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016426 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0021625 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16222339 | J:103365
First Author: Zan H
Year: 2005
Journal: EMBO J
Title: The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation.
Volume: 24
Issue: 21
Pages: 3757-69
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Publication
32234782 | J:287298
First Author: Carvajal-Garcia J
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Mechanistic basis for microhomology identification and genome scarring by polymerase theta.
Volume: 117
Issue: 15
Pages: 8476-8485
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Publication
29058711 | J:340661
First Author: Mateos-Gomez PA
Year: 2017
Journal: Nat Struct Mol Biol
Title: The helicase domain of Polθ counteracts RPA to promote alt-NHEJ.
Volume: 24
Issue: 12
Pages: 1116-1123
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Publication
28687761 | J:249698
First Author: Zelensky AN
Year: 2017
Journal: Nat Commun
Title: Inactivation of Pol θ and C-NHEJ eliminates off-target integration of exogenous DNA.
Volume: 8
Issue: 1
Pages: 66
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Publication
16436048 | J:111913
First Author: Ukai A
Year: 2006
Journal: Genes Cells
Title: Role of DNA polymerase theta in tolerance of endogenous and exogenous DNA damage in mouse B cells.
Volume: 11
Issue: 2
Pages: 111-21
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Publication
27453047 | J:249194
First Author: Wyatt DW
Year: 2016
Journal: Mol Cell
Title: Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks.
Volume: 63
Issue: 4
Pages: 662-673
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GXD Expression
GXD Expression
     
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: Kidney
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: Brain
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3283428
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: Small Intestine
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3526893
Assay Type: Northern blot
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1893928
Stage: TS28
Assay Id: MGI:3531214
Age: postnatal adult
Specimen Label: colon
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Brain
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Sk. Muscle
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Lung
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Testis
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Spleen
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3531215
Age: postnatal adult
Specimen Label: Kidney
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3531215
Age: embryonic day 7.0
Specimen Label: Embryo 7d
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3531215
Age: embryonic day 11.0
Specimen Label: Embryo 11d
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3531215
Age: embryonic day 15.0
Specimen Label: Embryo 15d
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:3526894
Assay Type: RT-PCR
Annotation Date: 2005-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3531215
Age: embryonic day 17.0
Specimen Label: Embryo 17d
Detected: true
Specimen Num: 12
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Publication
12794064 | J:85120
First Author: Marini F
Year: 2003
Journal: J Biol Chem
Title: POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308.
Volume: 278
Issue: 34
Pages: 32014-9
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Publication
16172387 | J:101409
First Author: Masuda K
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.
Volume: 102
Issue: 39
Pages: 13986-91
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Publication
18485835 | J:138141
First Author: Martomo SA
Year: 2008
Journal: DNA Repair (Amst)
Title: Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.
Volume: 7
Issue: 9
Pages: 1603-8
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Publication
28570559 | J:241704
First Author: Takata KI
Year: 2017
Journal: PLoS Genet
Title: Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance.
Volume: 13
Issue: 6
Pages: e1006818
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Publication
36580665 | J:337724
First Author: Vekariya U
Year: 2023
Journal: Blood
Title: DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.
Volume: 141
Issue: 19
Pages: 2372-2389
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Gene
487837 | HELQ
Type: gene
Organism: dog, domestic
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Gene
461278 | HELQ
Type: gene
Organism: chimpanzee
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Gene
539372 | HELQ
Type: gene
Organism: cattle
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Gene
562952 | helq
Type: gene
Organism: zebrafish
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Gene
707364 | HELQ
Type: gene
Organism: macaque, rhesus
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Gene
100485183 | helq
Type: gene
Organism: frog, western clawed
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Publication
36077614 | J:328883
 
First Author: Smolinska A
Year: 2022
Journal: Cancers (Basel)
Title: DNA Polymerase Theta Plays a Critical Role in Pancreatic Cancer Development and Metastasis.
Volume: 14
Issue: 17
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Publication
28176781 | J:244154
 
First Author: Zan H
Year: 2017
Journal: Nat Commun
Title: Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination.
Volume: 8
Pages: 14244
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Publication
32492419 | J:306456
First Author: Farini D
Year: 2020
Journal: Cell Rep
Title: A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.
Volume: 31
Issue: 9
Pages: 107703
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:346132
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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