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Search results 1 to 100 out of 475 for Por

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0.039s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: pig, domestic
Gene
Type: gene
Organism: guinea pig
Gene
Type: gene
Organism: hamster, Chinese
Gene
Type: gene
Organism: rabbit, European
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Por ED
Year: 2012
Journal: J Biol Chem
Title: β-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel.
Volume: 287
Issue: 44
Pages: 37552-63
Publication
First Author: Uehara S
Year: 2022
Journal: Sci Rep
Title: Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism.
Volume: 12
Issue: 1
Pages: 14907
Author
Publication
First Author: Finn RD
Year: 2009
Journal: Biochem J
Title: Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway.
Volume: 417
Issue: 1
Pages: 43-54
Publication
First Author: Finn RD
Year: 2007
Journal: J Pharmacol Exp Ther
Title: Conditional deletion of cytochrome P450 oxidoreductase in the liver and gastrointestinal tract: a new model for studying the functions of the P450 system.
Volume: 322
Issue: 1
Pages: 40-7
Publication
First Author: Barzi M
Year: 2017
Journal: Nat Commun
Title: A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism.
Volume: 8
Issue: 1
Pages: 39
Publication
First Author: Levová K
Year: 2011
Journal: Toxicol Sci
Title: Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model.
Volume: 121
Issue: 1
Pages: 43-56
Publication
First Author: Lee C
Year: 2013
Journal: Drug Metab Dispos
Title: The role of cytochrome P450-dependent metabolism in the regulation of mouse hepatic growth hormone signaling components and target genes by 3-methylcholanthrene.
Volume: 41
Issue: 2
Pages: 457-65
Publication  
First Author: Malacarne PF
Year: 2022
Journal: Int J Mol Sci
Title: Epoxyeicosatrienoic Acid and Prostanoid Crosstalk at the Receptor and Intracellular Signaling Levels to Maintain Vascular Tone.
Volume: 23
Issue: 11
Publication  
First Author: Reed L
Year: 2019
Journal: Toxicol Appl Pharmacol
Title: Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine.
Volume: 366
Pages: 64-74
Publication  
First Author: Lopez M
Year: 2022
Journal: Front Physiol
Title: Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling.
Volume: 13
Pages: 1056369
Publication
First Author: Henderson CJ
Year: 2015
Journal: Biochem J
Title: Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability.
Volume: 465
Issue: 3
Pages: 479-88
Publication
First Author: D'Agostino J
Year: 2012
Journal: J Biol Chem
Title: Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes.
Volume: 287
Issue: 21
Pages: 17777-88
Publication  
First Author: Wang H
Year: 2016
Journal: Sci Rep
Title: Oscillating primary transcripts harbor miRNAs with circadian functions.
Volume: 6
Pages: 21598
Publication
First Author: Panda SP
Year: 2013
Journal: PLoS One
Title: Conditional deletion of cytochrome p450 reductase in osteoprogenitor cells affects long bone and skull development in mice recapitulating antley-bixler syndrome: role of a redox enzyme in development.
Volume: 8
Issue: 9
Pages: e75638
Publication
First Author: Schmidt K
Year: 2009
Journal: Mol Cell Biol
Title: Cholesterol metabolism: the main pathway acting downstream of cytochrome P450 oxidoreductase in skeletal development of the limb.
Volume: 29
Issue: 10
Pages: 2716-29
Publication
First Author: Ribes V
Year: 2007
Journal: Dev Biol
Title: Rescue of cytochrome P450 oxidoreductase (Por) mouse mutants reveals functions in vasculogenesis, brain and limb patterning linked to retinoic acid homeostasis.
Volume: 303
Issue: 1
Pages: 66-81
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Ohgiya S
Year: 1994
Journal: Biochim Biophys Acta
Title: Mouse NADPH-cytochrome P-450 oxidoreductase: molecular cloning and functional expression in yeast.
Volume: 1186
Issue: 1-2
Pages: 137-41
Publication  
First Author: Ahlawat S
Year: 2014
Journal: Sci Rep
Title: Mice deficient in intestinal epithelium cytochrome P450 reductase are prone to acute toxin-induced mucosal damage.
Volume: 4
Pages: 5551
Publication
First Author: Zhang QY
Year: 2009
Journal: Drug Metab Dispos
Title: An intestinal epithelium-specific cytochrome P450 (P450) reductase-knockout mouse model: direct evidence for a role of intestinal p450s in first-pass clearance of oral nifedipine.
Volume: 37
Issue: 3
Pages: 651-7
Publication
First Author: Weng Y
Year: 2007
Journal: Cancer Res
Title: Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice.
Volume: 67
Issue: 16
Pages: 7825-32
Publication
First Author: Henderson CJ
Year: 2003
Journal: J Biol Chem
Title: Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase.
Volume: 278
Issue: 15
Pages: 13480-6
Publication
First Author: Wang XJ
Year: 2005
Journal: Biochem J
Title: Relationship between hepatic phenotype and changes in gene expression in cytochrome P450 reductase (POR) null mice.
Volume: 388
Issue: Pt 3
Pages: 857-67
Publication
First Author: Pass GJ
Year: 2005
Journal: Cancer Res
Title: Role of hepatic cytochrome p450s in the pharmacokinetics and toxicity of cyclophosphamide: studies with the hepatic cytochrome p450 reductase null mouse.
Volume: 65
Issue: 10
Pages: 4211-7
Publication
First Author: Kunne C
Year: 2014
Journal: Biochim Biophys Acta
Title: FXR-dependent reduction of hepatic steatosis in a bile salt deficient mouse model.
Volume: 1842
Issue: 5
Pages: 739-46
Publication
First Author: Shen AL
Year: 2002
Journal: J Biol Chem
Title: Association of multiple developmental defects and embryonic lethality with loss of microsomal NADPH-cytochrome P450 oxidoreductase.
Volume: 277
Issue: 8
Pages: 6536-41
Publication
First Author: Gu J
Year: 2003
Journal: J Biol Chem
Title: Liver-specific deletion of the NADPH-cytochrome P450 reductase gene: impact on plasma cholesterol homeostasis and the function and regulation of microsomal cytochrome P450 and heme oxygenase.
Volume: 278
Issue: 28
Pages: 25895-901
Publication
First Author: Wu L
Year: 2005
Journal: J Pharmacol Exp Ther
Title: Transgenic mice with a hypomorphic NADPH-cytochrome P450 reductase gene: effects on development, reproduction, and microsomal cytochrome P450.
Volume: 312
Issue: 1
Pages: 35-43
Publication
First Author: Weng Y
Year: 2005
Journal: J Biol Chem
Title: Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype.
Volume: 280
Issue: 36
Pages: 31686-98
Publication
First Author: Chipinda I
Year: 2011
Journal: Toxicol Appl Pharmacol
Title: Discrimination of haptens from prohaptens using the metabolically deficient Cpr(low/low) mouse.
Volume: 252
Issue: 3
Pages: 268-72
Publication  
First Author: Yao Y
Year: 2013
Journal: Neurosci Lett
Title: Suppression of cytochrome P450 reductase expression promotes astrocytosis in subventricular zone of adult mice.
Volume: 548
Pages: 84-9
Publication
First Author: Zhang Y
Year: 2013
Journal: PLoS One
Title: Suppression of cytochrome p450 reductase enhances long-term hematopoietic stem cell repopulation efficiency in mice.
Volume: 8
Issue: 7
Pages: e69913
Publication
First Author: Wei Y
Year: 2010
Journal: J Pharmacol Exp Ther
Title: Generation of a mouse model with a reversible hypomorphic cytochrome P450 reductase gene: utility for tissue-specific rescue of the reductase expression, and insights from a resultant mouse model with global suppression of P450 reductase expression in extrahepatic tissues.
Volume: 334
Issue: 1
Pages: 69-77
Publication
First Author: Wu L
Year: 2003
Journal: Genesis
Title: Conditional knockout of the mouse NADPH-cytochrome p450 reductase gene.
Volume: 36
Issue: 4
Pages: 177-81
Publication
First Author: Liu S
Year: 2013
Journal: Toxicol Appl Pharmacol
Title: The role of renal proximal tubule P450 enzymes in chloroform-induced nephrotoxicity: utility of renal specific P450 reductase knockout mouse models.
Volume: 272
Issue: 1
Pages: 230-7
Publication
First Author: Arlt VM
Year: 2005
Journal: Cancer Res
Title: Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols.
Volume: 65
Issue: 7
Pages: 2644-52
Publication
First Author: Mutch DM
Year: 2006
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver.
Volume: 291
Issue: 1
Pages: G63-72
Publication
First Author: Conroy JL
Year: 2010
Journal: Nat Neurosci
Title: Opioids activate brain analgesic circuits through cytochrome P450/epoxygenase signaling.
Volume: 13
Issue: 3
Pages: 284-6
Publication  
First Author: Fang C
Year: 2012
Journal: Neuroscience
Title: Neurobehavioral abnormalities in a brain-specific NADPH-cytochrome P450 reductase knockout mouse model.
Volume: 218
Pages: 170-80
Publication
First Author: Li Z
Year: 2012
Journal: Toxicol Sci
Title: PAH particles perturb prenatal processes and phenotypes: protection from deficits in object discrimination afforded by dampening of brain oxidoreductase following in utero exposure to inhaled benzo(a)pyrene.
Volume: 125
Issue: 1
Pages: 233-47
Publication
First Author: Shephard EA
Year: 1989
Journal: Ann Hum Genet
Title: Isolation of a human cytochrome P-450 reductase cDNA clone and localization of the corresponding gene to chromosome 7q11.2.
Volume: 53
Issue: Pt 4
Pages: 291-301
GXD Expression    
Probe: MGI:2653750
Assay Type: RT-PCR
Annotation Date: 2003-04-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2653763
Age: postnatal adult
Image: 3
Specimen Label: P450 reductase +
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:2653750
Assay Type: RT-PCR
Annotation Date: 2003-04-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:2653778
Age: embryonic day 3.5
Image: 3
Specimen Label: P450 reductase +
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5912421
Assay Type: Western blot
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1742822
Stage: TS22
Assay Id: MGI:5912429
Age: embryonic day 14.5
Image: 4
Specimen Label: forefoot
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5912421
Assay Type: Western blot
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1745922
Stage: TS22
Assay Id: MGI:5912429
Age: embryonic day 14.5
Image: 4
Specimen Label: hindfoot
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5912421
Assay Type: Western blot
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:5912429
Age: embryonic day 14.5
Image: 4
Specimen Label: skin
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5912421
Assay Type: Western blot
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1654222
Stage: TS22
Assay Id: MGI:5912429
Age: embryonic day 14.5
Image: 4
Specimen Label: nose
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5912421
Assay Type: Western blot
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672822
Stage: TS22
Assay Id: MGI:5912429
Age: embryonic day 14.5
Image: 4
Specimen Label: lung
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5912421
Assay Type: Western blot
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:5912429
Age: embryonic day 14.5
Image: 4
Specimen Label: liver
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5912419
Assay Type: RT-PCR
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:5912428
Age: embryonic day 16.5-17.5
Image: 4
Specimen Label: liver +
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5912419
Assay Type: RT-PCR
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1872125
Stage: TS25
Assay Id: MGI:5912428
Age: embryonic day 16.5-17.5
Image: 4
Specimen Label: clavicle +
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5912419
Assay Type: RT-PCR
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1872225
Stage: TS25
Assay Id: MGI:5912428
Age: embryonic day 16.5-17.5
Image: 4
Specimen Label: scapula +
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5912419
Assay Type: RT-PCR
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752525
Stage: TS25
Assay Id: MGI:5912428
Age: embryonic day 16.5-17.5
Image: 4
Specimen Label: skin +
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5912419
Assay Type: RT-PCR
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610525
Stage: TS25
Assay Id: MGI:5912428
Age: embryonic day 16.5-17.5
Image: 4
Specimen Label: heart +
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5912419
Assay Type: RT-PCR
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271525
Stage: TS25
Assay Id: MGI:5912428
Age: embryonic day 16.5-17.5
Image: 4
Specimen Label: muscle +
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5912419
Assay Type: RT-PCR
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:5912439
Age: embryonic day 7.5
Specimen Label: E7.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5912419
Assay Type: RT-PCR
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:5912439
Age: embryonic day 9.5
Specimen Label: E9.5
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5912419
Assay Type: RT-PCR
Annotation Date: 2017-11-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:5912439
Age: embryonic day 10.5
Specimen Label: E10.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6315836
Assay Type: RT-PCR
Annotation Date: 2019-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842623
Stage: TS23
Assay Id: MGI:6315844
Age: embryonic day 14.5-15.5
Specimen Label: Red +
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6315836
Assay Type: RT-PCR
Annotation Date: 2019-07-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1842622
Stage: TS22
Assay Id: MGI:6315844
Age: embryonic day 14.5-15.5
Specimen Label: Red +
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6315836
Assay Type: RT-PCR
Annotation Date: 2019-07-02
Strength: Present
Sex: Female
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:6315853
Age: postnatal adult
Specimen Label: Red +
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7517170
Assay Type: RT-PCR
Annotation Date: 2023-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1671522
Stage: TS22
Assay Id: MGI:7518217
Age: embryonic day 14.5-15.5
Specimen Label: Red +
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7517170
Assay Type: RT-PCR
Annotation Date: 2023-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3704522
Stage: TS22
Assay Id: MGI:7518223
Age: embryonic day 14.5
Specimen Label: Red +
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3724846
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3516422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421498
Age: embryonic day 14.5
Image: MH1423; Specimen C1563
Specimen Label: MH1423; Specimen C1563
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1380475
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2966328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5538832
Age: postnatal day 84
Image: GUDMAP:15499
Specimen Label: GUDMAP:15499
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3724846
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5421498
Age: embryonic day 14.5
Image: MH1423; Specimen C1563
Specimen Label: MH1423; Specimen C1563
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1380475
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1912823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827335
Age: embryonic day 14.5
Image: euxassay_003208_06
Specimen Label: euxassay_003208_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1380475
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1912823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827335
Age: embryonic day 14.5
Image: euxassay_003208_07
Specimen Label: euxassay_003208_07
Detected: true
Specimen Num: 7