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Search results 1 to 100 out of 104 for Pot1b

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Type Details Score
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Wang Y
Year: 2011
Journal: Blood
Title: Essential roles for Pot1b in HSC self-renewal and survival.
Volume: 118
Issue: 23
Pages: 6068-77
Publication
First Author: He H
Year: 2006
Journal: EMBO J
Title: POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination.
Volume: 25
Issue: 21
Pages: 5180-90
Publication
First Author: Hagiwara M
Year: 2013
Journal: Biochem Biophys Res Commun
Title: POT1b regulates phagocytosis and NO production by modulating activity of the small GTPase Rab5.
Volume: 439
Issue: 3
Pages: 413-7
Publication
First Author: He H
Year: 2009
Journal: Mol Cell Biol
Title: Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita.
Volume: 29
Issue: 1
Pages: 229-40
Publication
First Author: Autexier C
Year: 2008
Journal: Genes Dev
Title: POT of gold: modeling dyskeratosis congenita in the mouse.
Volume: 22
Issue: 13
Pages: 1731-6
Publication
First Author: Hockemeyer D
Year: 2006
Journal: Cell
Title: Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres.
Volume: 126
Issue: 1
Pages: 63-77
Publication
First Author: Hockemeyer D
Year: 2008
Journal: Genes Dev
Title: Engineered telomere degradation models dyskeratosis congenita.
Volume: 22
Issue: 13
Pages: 1773-85
Publication
First Author: Kibe T
Year: 2010
Journal: Mol Cell Biol
Title: Telomere protection by TPP1 is mediated by POT1a and POT1b.
Volume: 30
Issue: 4
Pages: 1059-66
Publication
First Author: Lagunas AM
Year: 2019
Journal: Mol Cancer Res
Title: Paracrine Interaction of Cancer Stem Cell Populations Is Regulated by the Senescence-Associated Secretory Phenotype (SASP).
Volume: 17
Issue: 7
Pages: 1480-1492
Publication
First Author: Palm W
Year: 2009
Journal: Mol Cell Biol
Title: Functional dissection of human and mouse POT1 proteins.
Volume: 29
Issue: 2
Pages: 471-82
Publication
First Author: Frescas D
Year: 2014
Journal: Mol Cell Biol
Title: TRF2-tethered TIN2 can mediate telomere protection by TPP1/POT1.
Volume: 34
Issue: 7
Pages: 1349-62
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kappei D
Year: 2013
Journal: EMBO J
Title: HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment.
Volume: 32
Issue: 12
Pages: 1681-701
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Overbeek PA
Year: 2011
Journal: MGI Direct Data Submission
Title: Direct Data Submission for Overbeek Lentiviral Transgenic Lines
Publication
First Author: Denchi EL
Year: 2009
Journal: DNA Repair (Amst)
Title: Give me a break: how telomeres suppress the DNA damage response.
Volume: 8
Issue: 9
Pages: 1118-26
Publication
First Author: Wang Y
Year: 2013
Journal: J Clin Invest
Title: p16(INK4a) protects against dysfunctional telomere-induced ATR-dependent DNA damage responses.
Volume: 123
Issue: 10
Pages: 4489-501
Publication
First Author: Wu L
Year: 2006
Journal: Cell
Title: Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres.
Volume: 126
Issue: 1
Pages: 49-62
Publication
First Author: Wang Y
Year: 2016
Journal: Aging Cell
Title: Dysfunctional telomeres induce p53-dependent and independent apoptosis to compromise cellular proliferation and inhibit tumor formation.
Volume: 15
Issue: 4
Pages: 646-60
Publication
First Author: Gong Y
Year: 2017
Journal: Genes Dev
Title: PHF11 promotes DSB resection, ATR signaling, and HR.
Volume: 31
Issue: 1
Pages: 46-58
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Doksani Y
Year: 2013
Journal: Cell
Title: Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation.
Volume: 155
Issue: 2
Pages: 345-356
Publication
First Author: Hockemeyer D
Year: 2007
Journal: Nat Struct Mol Biol
Title: Telomere protection by mammalian Pot1 requires interaction with Tpp1.
Volume: 14
Issue: 8
Pages: 754-61
Publication
First Author: Wu P
Year: 2008
Journal: Mol Cell Biol
Title: No overt nucleosome eviction at deprotected telomeres.
Volume: 28
Issue: 18
Pages: 5724-35
Publication
First Author: Mirman Z
Year: 2018
Journal: Nature
Title: 53BP1-RIF1-shieldin counteracts DSB resection through CST- and PolĪ±-dependent fill-in.
Volume: 560
Issue: 7716
Pages: 112-116
GXD Expression      
Probe: MGI:3692937
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3692938
Age: postnatal adult
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3692950
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3692954
Age: postnatal
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3692937
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3692938
Age: postnatal adult
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:3692950
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3692954
Age: postnatal
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3692937
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3692938
Age: postnatal adult
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3692950
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3692954
Age: postnatal
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3692937
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3692938
Age: postnatal adult
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:3692937
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3692938
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3692950
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3692954
Age: postnatal
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3692937
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3692938
Age: embryonic day 7.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3692937
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3692938
Age: embryonic day 11.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3692937
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3692938
Age: embryonic day 15.0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3692937
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3692938
Age: embryonic day 17.0
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3692950
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:3692954
Age: embryonic day 7.0
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3692950
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:3692954
Age: embryonic day 11.0
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:3692950
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3692954
Age: embryonic day 15.0
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:3692950
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3692954
Age: embryonic day 17.0
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:3692937
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3692938
Age: postnatal adult
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:3692950
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3692954
Age: postnatal
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3692937
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3692938
Age: postnatal adult
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:3692950
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3692954
Age: postnatal
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3692950
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:3692954
Age: postnatal
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3692937
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3692938
Age: postnatal adult
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3692950
Assay Type: RT-PCR
Annotation Date: 2007-01-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3692954
Age: postnatal
Detected: true
Specimen Num: 2
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Interaction Experiment
Description: POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination.
Interaction Experiment
Description: POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination.
Interaction Experiment
Description: POT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombination.
Publication
First Author: Baumann P
Year: 2010
Journal: FEBS Lett
Title: Pot1 and telomere maintenance.
Volume: 584
Issue: 17
Pages: 3779-84
Publication
First Author: Trujillo KM
Year: 2005
Journal: J Biol Chem
Title: Extended DNA binding site in Pot1 broadens sequence specificity to allow recognition of heterogeneous fission yeast telomeres.
Volume: 280
Issue: 10
Pages: 9119-28
Publication
First Author: Surovtseva YV
Year: 2007
Journal: EMBO J
Title: Arabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance.
Volume: 26
Issue: 15
Pages: 3653-61
Publication
First Author: Wu Y
Year: 2013
Journal: J Proteome Res
Title: Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation.
Volume: 12
Issue: 1
Pages: 316-27
Protein Domain
Type: Family
Description: In most eukaryotes, their chromosome ends are composed of a single stranded overhang that contains GT-rich repeats and are bound by telomerase ribonucleoproteins (RNPs).This entry represents a group of telomere binding proteins, including the protection of telomeres protein 1 (POT1) from humans/fission yeast/plants, the telomere end binding proteins (TEBP) alpha from the hypotrichous ciliate Oxytricha nova and Cdc13 from Saccharomyces cerevisiae. They are ribonucleoproteins (RNPs) that play an important role in telomere maintenance, but the precise roles played in end protection and telomere length regulation seem to vary considerably between organisms [, ]. In fission yeast, POT1 prevents access of telomerase to the 3'-end and protects against exonucleolytic degradation []. However, in humans, POT1 might function predominantly in telomere length regulation rather than in the protection of telomeres []. In Arabidopsis, there are several POT-like proteins, including POT1a, POT1b and POT1c []. POT1a and POT1b are components of telomerase rather than telomere capping components []. In Saccharomyces cerevisiae an OB-fold containing protein called Cdc13 plays a similar role as POT1, such as single-stranded G-rich telomeric DNA binding and telomere maintenance [, ].
Protein
Organism: Mus musculus
Length: 640  
Fragment?: false
Protein
Organism: Mus musculus
Length: 640  
Fragment?: false
Protein
Organism: Mus musculus
Length: 352  
Fragment?: false
Protein
Organism: Mus musculus
Length: 325  
Fragment?: false
Protein
Organism: Mus musculus
Length: 623  
Fragment?: false