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Search results 1 to 100 out of 1058 for Ppargc1a

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0.053s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression    
Probe: MGI:6181057
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191133
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Ppargc1a
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6181057
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191133
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Ppargc1a
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6181057
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191133
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Ppargc1a
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:6181057
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191133
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Ppargc1a
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6181057
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191133
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Ppargc1a
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6181057
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191133
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Ppargc1a
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6181057
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191133
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Ppargc1a
Detected: true
Specimen Num: 6
Publication
First Author: Valtat B
Year: 2013
Journal: Diabetes
Title: Fetal PGC-1α overexpression programs adult pancreatic β-cell dysfunction.
Volume: 62
Issue: 4
Pages: 1206-16
Publication
First Author: Tsunemi T
Year: 2012
Journal: Sci Transl Med
Title: PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.
Volume: 4
Issue: 142
Pages: 142ra97
Publication
First Author: Wende AR
Year: 2007
Journal: J Biol Chem
Title: A role for the transcriptional coactivator PGC-1alpha in muscle refueling.
Volume: 282
Issue: 50
Pages: 36642-51
Publication  
First Author: Soyal SM
Year: 2019
Journal: Neurobiol Dis
Title: The PPARGC1A locus and CNS-specific PGC-1α isoforms are associated with Parkinson's Disease.
Volume: 121
Pages: 34-46
Publication
First Author: Russell LK
Year: 2004
Journal: Circ Res
Title: Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner.
Volume: 94
Issue: 4
Pages: 525-33
Publication
First Author: Tran MT
Year: 2016
Journal: Nature
Title: PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.
Volume: 531
Issue: 7595
Pages: 528-32
Publication
First Author: Han SH
Year: 2017
Journal: J Am Soc Nephrol
Title: PGC-1α Protects from Notch-Induced Kidney Fibrosis Development.
Volume: 28
Issue: 11
Pages: 3312-3322
Publication    
First Author: Rosenkranz SC
Year: 2021
Journal: Elife
Title: Enhancing mitochondrial activity in neurons protects against neurodegeneration in a mouse model of multiple sclerosis.
Volume: 10
Publication
First Author: Quattrocelli M
Year: 2022
Journal: Sci Adv
Title: Muscle mitochondrial remodeling by intermittent glucocorticoid drugs requires an intact circadian clock and muscle PGC1α.
Volume: 8
Issue: 7
Pages: eabm1189
Publication    
First Author: Lynch MR
Year: 2019
Journal: JCI Insight
Title: TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance.
Volume: 5
Publication
First Author: Larson-Casey JL
Year: 2021
Journal: FASEB J
Title: Post-translational regulation of PGC-1α modulates fibrotic repair.
Volume: 35
Issue: 6
Pages: e21675
Publication
First Author: Guo X
Year: 2014
Journal: Am J Pathol
Title: PGC-1α signaling coordinates susceptibility to metabolic and oxidative injury in the inner retina.
Volume: 184
Issue: 4
Pages: 1017-29
Publication
First Author: Ho BS
Year: 2019
Journal: Sci Rep
Title: Progressive expression of PPARGC1α is associated with hair miniaturization in androgenetic alopecia.
Volume: 9
Issue: 1
Pages: 8771
Publication
First Author: Wang J
Year: 2020
Journal: Biochem Biophys Res Commun
Title: PGC-1α regulate critical period plasticity via gene × environment interaction in the developmental trajectory to schizophrenia.
Volume: 525
Issue: 4
Pages: 989-996
Publication
First Author: Jang C
Year: 2016
Journal: Nat Med
Title: A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.
Volume: 22
Issue: 4
Pages: 421-6
Publication
First Author: Hasumi Y
Year: 2014
Journal: Hum Mol Genet
Title: Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation.
Volume: 23
Issue: 21
Pages: 5706-19
Publication
First Author: Shoag J
Year: 2013
Journal: Mol Cell
Title: PGC-1 coactivators regulate MITF and the tanning response.
Volume: 49
Issue: 1
Pages: 145-57
Publication  
First Author: Huang Z
Year: 2014
Journal: Nat Commun
Title: The stem cell factor/Kit signalling pathway regulates mitochondrial function and energy expenditure.
Volume: 5
Pages: 4282
Publication
First Author: Bayer H
Year: 2017
Journal: Neurobiol Dis
Title: ALS-causing mutations differentially affect PGC-1α expression and function in the brain vs. peripheral tissues.
Volume: 97
Issue: Pt A
Pages: 36-45
Publication
First Author: Hallenborg P
Year: 2016
Journal: Am J Physiol Endocrinol Metab
Title: p53 regulates expression of uncoupling protein 1 through binding and repression of PPARγ coactivator-1α.
Volume: 310
Issue: 2
Pages: E116-28
Publication
First Author: Yu B
Year: 2018
Journal: Cell Stem Cell
Title: PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ.
Volume: 23
Issue: 2
Pages: 193-209.e5
Publication
First Author: Sjögren RJO
Year: 2021
Journal: Diabetologia
Title: Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes.
Volume: 64
Issue: 9
Pages: 2077-2091
Publication
First Author: Hasumi H
Year: 2012
Journal: J Natl Cancer Inst
Title: Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN.
Volume: 104
Issue: 22
Pages: 1750-64
Publication
First Author: Choi J
Year: 2023
Journal: Mol Cancer Res
Title: Dynamic Intestinal Stem Cell Plasticity and Lineage Remodeling by a Nutritional Environment Relevant to Human Risk for Tumorigenesis.
Volume: 21
Issue: 8
Pages: 808-824
Publication
First Author: Pérez S
Year: 2019
Journal: J Pathol
Title: Obesity causes PGC-1α deficiency in the pancreas leading to marked IL-6 upregulation via NF-κB in acute pancreatitis.
Volume: 247
Issue: 1
Pages: 48-59
Publication
First Author: Zhang Y
Year: 2018
Journal: Autophagy
Title: TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose.
Volume: 14
Issue: 11
Pages: 1959-1975
Publication
First Author: Besse-Patin A
Year: 2017
Journal: Gastroenterology
Title: Estrogen Signals Through Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α to Reduce Oxidative Damage Associated With Diet-Induced Fatty Liver Disease.
Volume: 152
Issue: 1
Pages: 243-256
Publication
First Author: Long J
Year: 2016
Journal: J Clin Invest
Title: Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy.
Volume: 126
Issue: 11
Pages: 4205-4218
Publication
First Author: Sweeney TE
Year: 2010
Journal: PLoS One
Title: Differential regulation of the PGC family of genes in a mouse model of Staphylococcus aureus sepsis.
Volume: 5
Issue: 7
Pages: e11606
Publication
First Author: Sawada N
Year: 2014
Journal: Cell Metab
Title: Endothelial PGC-1α mediates vascular dysfunction in diabetes.
Volume: 19
Issue: 2
Pages: 246-58
Publication
First Author: Sweeney TE
Year: 2011
Journal: PLoS One
Title: A toll-like receptor 2 pathway regulates the Ppargc1a/b metabolic co-activators in mice with Staphylococcal aureus sepsis.
Volume: 6
Issue: 9
Pages: e25249
Publication
First Author: Salazar G
Year: 2020
Journal: Autophagy
Title: SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence.
Volume: 16
Issue: 6
Pages: 1092-1110
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Jäger S
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha.
Volume: 104
Issue: 29
Pages: 12017-22
Publication
First Author: Puigserver P
Year: 1998
Journal: Cell
Title: A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.
Volume: 92
Issue: 6
Pages: 829-39
Publication
First Author: Ruas JL
Year: 2012
Journal: Cell
Title: A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy.
Volume: 151
Issue: 6
Pages: 1319-31
Publication
First Author: Cho Y
Year: 2013
Journal: J Biol Chem
Title: Peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells.
Volume: 288
Issue: 35
Pages: 25207-18
Publication
First Author: Svensson K
Year: 2016
Journal: PLoS One
Title: Loss of Renal Tubular PGC-1α Exacerbates Diet-Induced Renal Steatosis and Age-Related Urinary Sodium Excretion in Mice.
Volume: 11
Issue: 7
Pages: e0158716
Publication
First Author: Wang J
Year: 2019
Journal: Neuropsychobiology
Title: Mice Lacking the Transcriptional Coactivator PGC-1α Exhibit Hyperactivity.
Volume: 78
Issue: 4
Pages: 182-188
Publication
First Author: Buch BT
Year: 2020
Journal: FASEB J
Title: Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in an age-specific manner.
Volume: 34
Issue: 6
Pages: 8653-8670
Publication
First Author: Kärkkäinen O
Year: 2019
Journal: Cardiovasc Res
Title: Heart specific PGC-1α deletion identifies metabolome of cardiac restricted metabolic heart failure.
Volume: 115
Issue: 1
Pages: 107-118
Publication
First Author: Patten IS
Year: 2012
Journal: Nature
Title: Cardiac angiogenic imbalance leads to peripartum cardiomyopathy.
Volume: 485
Issue: 7398
Pages: 333-8
Publication  
First Author: Novak EA
Year: 2023
Journal: Front Immunol
Title: Epithelial NAD(+) depletion drives mitochondrial dysfunction and contributes to intestinal inflammation.
Volume: 14
Pages: 1231700
Publication
First Author: Hou Y
Year: 2022
Journal: Cell Mol Gastroenterol Hepatol
Title: Epithelial SMYD5 Exaggerates IBD by Down-regulating Mitochondrial Functions via Post-Translational Control of PGC-1α Stability.
Volume: 14
Issue: 2
Pages: 375-403
Publication
First Author: Cunningham KE
Year: 2016
Journal: J Biol Chem
Title: Peroxisome Proliferator-activated Receptor-γ Coactivator 1-α (PGC1α) Protects against Experimental Murine Colitis.
Volume: 291
Issue: 19
Pages: 10184-200
Publication
First Author: Tadaishi M
Year: 2011
Journal: PLoS One
Title: Skeletal muscle-specific expression of PGC-1α-b, an exercise-responsive isoform, increases exercise capacity and peak oxygen uptake.
Volume: 6
Issue: 12
Pages: e28290
Publication
First Author: Su X
Year: 2015
Journal: PLoS One
Title: PGC-1α Promoter Methylation in Parkinson's Disease.
Volume: 10
Issue: 8
Pages: e0134087
Publication
First Author: Kleiner S
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Development of insulin resistance in mice lacking PGC-1α in adipose tissues.
Volume: 109
Issue: 24
Pages: 9635-40
Publication
First Author: Sczelecki S
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Loss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation.
Volume: 306
Issue: 2
Pages: E157-67
Publication
First Author: Gill JF
Year: 2019
Journal: Aging Cell
Title: Peroxisome proliferator-activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging.
Volume: 18
Issue: 5
Pages: e12993
Publication
First Author: de Smalen LM
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Impaired age-associated mitochondrial translation is mitigated by exercise and PGC-1α.
Volume: 120
Issue: 36
Pages: e2302360120
Publication
First Author: Finley LW
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction.
Volume: 109
Issue: 8
Pages: 2931-6
Publication
First Author: Handschin C
Year: 2007
Journal: J Biol Chem
Title: Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals.
Volume: 282
Issue: 41
Pages: 30014-21
Publication
First Author: Handschin C
Year: 2007
Journal: J Clin Invest
Title: Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk.
Volume: 117
Issue: 11
Pages: 3463-74
Publication
First Author: Geng T
Year: 2010
Journal: Am J Physiol Cell Physiol
Title: PGC-1alpha plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle.
Volume: 298
Issue: 3
Pages: C572-9
Publication
First Author: Svensson K
Year: 2016
Journal: FASEB J
Title: Skeletal muscle PGC-1α modulates systemic ketone body homeostasis and ameliorates diabetic hyperketonemia in mice.
Volume: 30
Issue: 5
Pages: 1976-86
Publication
First Author: Schnyder S
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: Muscle PGC-1α is required for long-term systemic and local adaptations to a ketogenic diet in mice.
Volume: 312
Issue: 5
Pages: E437-E446
Publication  
First Author: Fujiwara T
Year: 2023
Journal: JCI Insight
Title: PGC-1α-mediated angiogenesis prevents pulmonary hypertension in mice.
Volume: 8
Issue: 17
Publication
First Author: Chandra R
Year: 2017
Journal: Biol Psychiatry
Title: A Role for Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1α in Nucleus Accumbens Neuron Subtypes in Cocaine Action.
Volume: 81
Issue: 7
Pages: 564-572
Publication
First Author: Leone TC
Year: 2005
Journal: PLoS Biol
Title: PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.
Volume: 3
Issue: 4
Pages: e101
Publication
First Author: Gong B
Year: 2013
Journal: Neurobiol Aging
Title: Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models.
Volume: 34
Issue: 6
Pages: 1581-8
Publication
First Author: Jun HJ
Year: 2014
Journal: Diabetes
Title: NT-PGC-1α activation attenuates high-fat diet-induced obesity by enhancing brown fat thermogenesis and adipose tissue oxidative metabolism.
Volume: 63
Issue: 11
Pages: 3615-25
Publication
First Author: Burgess SC
Year: 2006
Journal: J Biol Chem
Title: Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice.
Volume: 281
Issue: 28
Pages: 19000-8
Publication
First Author: Xiang Z
Year: 2011
Journal: J Neurosci
Title: Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease.
Volume: 31
Issue: 26
Pages: 9544-53
Publication
First Author: Kim J
Year: 2016
Journal: PLoS One
Title: Regulation of Brown and White Adipocyte Transcriptome by the Transcriptional Coactivator NT-PGC-1α.
Volume: 11
Issue: 7
Pages: e0159990