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Search results 1 to 100 out of 113 for Ppp1cb

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Saadat M
Year: 1994
Journal: Jpn J Genet
Title: Chromosomal localization of human, rat, and mouse protein phosphatase type 1 beta catalytic subunit genes (PPP1CB) by fluorescence in situ hybridization.
Volume: 69
Issue: 6
Pages: 697-700
Publication
First Author: Deneyer N
Year: 2019
Journal: Biochim Biophys Acta Gene Regul Mech
Title: HOXA2 activity regulation by cytoplasmic relocation, protein stabilization and post-translational modification.
Volume: 1862
Issue: 9
Pages: 194404
Publication
First Author: Schmutz I
Year: 2011
Journal: PLoS One
Title: Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock.
Volume: 6
Issue: 6
Pages: e21325
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Chang AN
Year: 2018
Journal: J Biol Chem
Title: The dominant protein phosphatase PP1c isoform in smooth muscle cells, PP1cβ, is essential for smooth muscle contraction.
Volume: 293
Issue: 43
Pages: 16677-16686
GXD Expression      
Probe: MGI:3764710
Assay Type: RT-PCR
Annotation Date: 2007-12-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640517
Stage: TS17
Assay Id: MGI:3764709
Age: embryonic day 10.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4867668
Assay Type: Western blot
Annotation Date: 2011-01-13
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:4867677
Age: embryonic day 13.0
Image: S3
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:4353202
Assay Type: Western blot
Annotation Date: 2009-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287128
Stage: TS28
Assay Id: MGI:4353213
Age: postnatal week 4
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4353188
Assay Type: RT-PCR
Annotation Date: 2009-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287128
Stage: TS28
Assay Id: MGI:4353209
Age: postnatal week 4
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4353179
Assay Type: RT-PCR
Annotation Date: 2009-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287128
Stage: TS28
Assay Id: MGI:4353205
Age: postnatal week 4
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4353202
Assay Type: Western blot
Annotation Date: 2009-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716128
Stage: TS28
Assay Id: MGI:4353213
Age: postnatal week 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4353188
Assay Type: RT-PCR
Annotation Date: 2009-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716128
Stage: TS28
Assay Id: MGI:4353209
Age: postnatal week 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4353179
Assay Type: RT-PCR
Annotation Date: 2009-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716128
Stage: TS28
Assay Id: MGI:4353205
Age: postnatal week 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4353202
Assay Type: Western blot
Annotation Date: 2009-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:4353213
Age: postnatal week 4
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4353188
Assay Type: RT-PCR
Annotation Date: 2009-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:4353209
Age: postnatal week 4
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4353179
Assay Type: RT-PCR
Annotation Date: 2009-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716828
Stage: TS28
Assay Id: MGI:4353205
Age: postnatal week 4
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4353202
Assay Type: Western blot
Annotation Date: 2009-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1784128
Stage: TS28
Assay Id: MGI:4353213
Age: postnatal week 4
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4353188
Assay Type: RT-PCR
Annotation Date: 2009-08-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1784128
Stage: TS28
Assay Id: MGI:4353209
Age: postnatal week 4
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:4353179
Assay Type: RT-PCR
Annotation Date: 2009-08-17
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1784128
Stage: TS28
Assay Id: MGI:4353205
Age: postnatal week 4
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:2452537
Assay Type: RNA in situ
Annotation Date: 2007-12-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1640517
Stage: TS17
Assay Id: MGI:3764549
Age: embryonic day 10.5
Detected: false
Specimen Num: 1
Publication
First Author: Ohkura H
Year: 1989
Journal: Cell
Title: The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases.
Volume: 57
Issue: 6
Pages: 997-1007
Publication
First Author: Gräff J
Year: 2010
Journal: Learn Mem
Title: Protein phosphatase 1-dependent transcriptional programs for long-term memory and plasticity.
Volume: 17
Issue: 7
Pages: 355-63
Publication
First Author: Llorian M
Year: 2004
Journal: Biochem J
Title: SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1.
Volume: 378
Issue: Pt 1
Pages: 229-38
Publication
First Author: Luo X
Year: 2011
Journal: Diabetes
Title: Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis.
Volume: 60
Issue: 5
Pages: 1435-45
Publication
First Author: Parra M
Year: 2007
Journal: Genes Dev
Title: Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes.
Volume: 21
Issue: 6
Pages: 638-43
Publication
First Author: Brüchert N
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Inhibitor-2 prevents protein phosphatase 1-induced cardiac hypertrophy and mortality.
Volume: 295
Issue: 4
Pages: H1539-46
Publication
First Author: Garcia-Haro L
Year: 2012
Journal: FEBS Lett
Title: Glucose-dependent regulation of AMP-activated protein kinase in MIN6 beta cells is not affected by the protein kinase A pathway.
Volume: 586
Issue: 23
Pages: 4241-7
Publication
First Author: Lee HM
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1.
Volume: 108
Issue: 39
Pages: 16451-6
Publication
First Author: Traweger A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Protein phosphatase 1 regulates the phosphorylation state of the polarity scaffold Par-3.
Volume: 105
Issue: 30
Pages: 10402-7
Publication  
First Author: Liu WB
Year: 2008
Journal: Mol Vis
Title: Differential expression of the catalytic subunits for PP-1 and PP-2A and the regulatory subunits for PP-2A in mouse eye.
Volume: 14
Pages: 762-73
Publication
First Author: Rock JR
Year: 2007
Journal: Gene Expr Patterns
Title: Identification of genes expressed in the mouse limb using a novel ZPA microarray approach.
Volume: 8
Issue: 1
Pages: 19-26
Publication
First Author: Bose SK
Year: 2016
Journal: Endocrinology
Title: Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.
Volume: 157
Issue: 12
Pages: 4943-4960
Publication
First Author: Jiang CH
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: The effects of aging on gene expression in the hypothalamus and cortex of mice.
Volume: 98
Issue: 4
Pages: 1930-4
Publication
First Author: Alldred MJ
Year: 2015
Journal: J Comp Neurol
Title: Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice.
Volume: 523
Issue: 1
Pages: 61-74
Publication      
First Author: Lexicon Genetics Inc
Year: 2005
Journal: MGI Direct Data Submission
Title: NIH initiative supporting placement of Lexicon Genetics, Inc. mice into public repositories
Publication
First Author: Cobellis G
Year: 2005
Journal: Nucleic Acids Res
Title: Tagging genes with cassette-exchange sites.
Volume: 33
Issue: 4
Pages: e44
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics, the Protein Information Resource and the Protein Ontology Consortium
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
DO Term
GO Term
Publication
First Author: Lee JH
Year: 2010
Journal: J Biol Chem
Title: Identification and characterization of a novel human PP1 phosphatase complex.
Volume: 285
Issue: 32
Pages: 24466-76
Publication
First Author: Ito M
Year: 2004
Journal: Mol Cell Biochem
Title: Myosin phosphatase: structure, regulation and function.
Volume: 259
Issue: 1-2
Pages: 197-209
Publication
First Author: Zagórska A
Year: 2010
Journal: Sci Signal
Title: New roles for the LKB1-NUAK pathway in controlling myosin phosphatase complexes and cell adhesion.
Volume: 3
Issue: 115
Pages: ra25
Publication
First Author: Tang PM
Year: 1991
Journal: J Biol Chem
Title: Molecular cloning and expression of the regulatory (RG1) subunit of the glycogen-associated protein phosphatase.
Volume: 266
Issue: 24
Pages: 15782-9
Publication
First Author: Ceulemans H
Year: 2002
Journal: J Biol Chem
Title: Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1.
Volume: 277
Issue: 49
Pages: 47331-7
Publication
First Author: Connor JH
Year: 2001
Journal: Mol Cell Biol
Title: Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.
Volume: 21
Issue: 20
Pages: 6841-50
Publication
First Author: Mi J
Year: 2007
Journal: Cancer Res
Title: Protein phosphatase-1alpha regulates centrosome splitting through Nek2.
Volume: 67
Issue: 3
Pages: 1082-9
Publication
First Author: Song H
Year: 2015
Journal: Autophagy
Title: ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation.
Volume: 11
Issue: 8
Pages: 1308-25
Publication
First Author: Nie H
Year: 2013
Journal: Nat Med
Title: Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis.
Volume: 19
Issue: 3
Pages: 322-8
Protein Domain
Type: Family
Description: Serine/threonine-protein phosphatase PP1 () is a complex of a catalytic subunit, either PPP1CA, PPP1CB or PPP1CC, with one or more regulatory or targeting subunits. Example targeting subunits are PPP1R12A and PPP1R12C, which mediate binding of PP1 to myosin [,,]; PPP1R3A, which mediates binding to glycogen in the skeletal muscle []; PPP1R7, []; PPP1R15A, which mediates binding to EIF2S1 []. The phosphatase associates with any one of many other regulatory proteins to form a complex that dephosphorylates a specific target protein. For example, centrosome splitting is regulated by the association of NEK2 with PP1 via the PPP1CA subunit [], binding to ATG16L1 antagonizes casein kinase 2-mediated phosphorylation of ATG16L1 affecting the fate of cadiomyocytes []and association with TNF-a induces phosphorylation of FOXP3 which controls regulatory T cell function []. PP1 is required for the cell cycle [], cell division, glycogen metabolism [], muscle contraction []and protein synthesis. PPP1CA and PPP1CB are components of the PTW/PP1 phosphatase complex [].This entry includes the catalytic subunit gamma (PPP1CC) from mammals, Dis2 from fission yeasts and Glc7 from budding yeasts. Glc7 is also a component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB [].
Protein Domain
Type: Family
Description: This entry includes the catalytic subunits PP1-alpha (PPP1CA).Serine/threonine-protein phosphatase PP1 () is a complex of a catalytic subunit, either PPP1CA, PPP1CB or PPP1CC, with one or more regulatory or targeting subunits. Example targeting subunits are PPP1R12A and PPP1R12C, which mediate binding of PP1 to myosin [,,]; PPP1R3A, which mediates binding to glycogen in the skeletal muscle []; PPP1R7, []; PPP1R15A, which mediates binding to EIF2S1 []. The phosphatase associates with any one of many other regulatory proteins to form a complex that dephosphorylates a specific target protein. For example, centrosome splitting is regulated by the association of NEK2 with PP1 via the PPP1CA subunit [], binding to ATG16L1 antagonizes casein kinase 2-mediated phosphorylation of ATG16L1 affecting the fate of cadiomyocytes []and association with TNF-a induces phosphorylation of FOXP3 which controls regulatory T cell function []. PP1 is required for the cell cycle [], cell division, glycogen metabolism [], muscle contraction []and protein synthesis. PPP1CA and PPP1CB are components of the PTW/PP1 phosphatase complex [].